• Title/Summary/Keyword: miR-21

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Efficient Extraction Method of Black Tea using Mineral Water and Antioxidant and Anti-inflammatory Activity of Extract (미네랄 워터를 이용한 블랙티의 효율적 추출 방법 및 추출물의 항산화와 항염 효능)

  • Kim, Eun-Mi;Jung, Jiyong;Kim, Hyung-Min;Hwang, Kyeong Hwan;Kim, Hyoung-June;Park, Won-Seok
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.48 no.1
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    • pp.47-53
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    • 2022
  • In this study, the conditions for efficiently extracting polyphenols contained in black tea were optimized. In order to confirm the polyphenol content according to the degree of fermentation, the polyphenol content in black tea of the three fermentation degrees was compared. As the degree of fermentation increased, the polyphenol content increased, and it was confirmed that the theabrownin content, the largest in size, increased significantly. In addition, it was confirmed that the amount of theabrownin extraction increased by about 150% or more compared to other extraction water when extracting using mineral water, which was hard water. The antioxidant effects of black tea extract and the theabrownin was confirmed using ABTS assay. As a result, both extracts had antioxidant effects, and IC50 values were confirmed to be 10.60 ppm and 13.21 ppm, respectively. And also, the anti-inflammatory effect of the theabrownin was confirmed that the mRNA expression of IL-8 increased by UVB irradiation was inhibited in a concentration dependent manner by the theabrownin. In addition, when theabrownin was treated with 10 ppm, the mitochondrial function decreased by UVB irradiation was restored to 86 ± 1.9% compared to the control group. Therefore, we concluded that theabrownin could protect mitochondrial damage caused by UVB irradiation.

Influence of Emotional Intelligence, Communication Competence, and Interpersonal Competence on Adaptation to College Life in Nursing Students (간호대학생의 감성지능, 의사소통능력, 대인관계유능성이 대학생활적응에 미치는 영향)

  • Young-Hee Cho;Eun-Mi Lee;Yun-Jeong Oh
    • Journal of Industrial Convergence
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    • v.21 no.11
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    • pp.117-124
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    • 2023
  • This study is a descriptive research study to determine the relationship between nursing students' emotional intelligence, communication competence, interpersonal competence, and adaptation to college life, and to identify factors that adaptation to college life. The subjects of the study were 173 nursing students attending a university in G City, and data collection was conducted from September 10 to October 10, 2022 Descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis were performed on the collected data using SPSS 25.0 program. The results showed a significant positive correlation between emotional intelligence(r=.760, p<.001), communication competence(r=.600, p<.001), and interpersonal competence(r=.451, p<.001). Factors that have a significant impact on adaptation to college life include emotional intelligence(𝛽=.543, p<.001), communication competence(𝛽=.433, p=.001), and interpersonal competence(𝛽=.283, p<.031). The total explanatory power of these variables on adaptation to college life was 59.9%, and emotional intelligence was confirmed to be the main influencing factor.

Effect of Integrated-Simulation Practice Education on Nursing Students' Communication Ability, Learning Confidence, Clinical Reasoning Competence, and Clinical Performance (통합시뮬레이션 실습 교육이 간호대학생의 의사소통능력, 학습자신감, 임상추론역량, 임상수행능력에 미치는 효과)

  • Mi-Jung Kim;Eun-Ha Na
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.683-692
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    • 2024
  • This study aimed to examine the effects of integrated simulation practice education for nursing college students on their communication skills, self-efficacy in learning, clinical reasoning ability, and clinical performance through a pre-post quasi-experimental design with a single group. The participants were 41 fourth-year nursing college students from a university located in G City, and the intervention took place from September to November 2023 over a period of nine weeks. The collected data were analyzed using SPSS 23.0, and the research findings are as follows. First, after simulation practice education, significant effects were observed in self-efficacy in learning (t=-2.21, p=.033), clinical reasoning ability (t=-2.97, p=.005), and clinical performance (t=-2.84, p=.007), but no significant difference was found in communication skills (t=-.224, p=.824). Second, after simulation classes for nursing students, clinical performance showed significant positive correlations with communication skills (r=.650, p<.001), self-efficacy in learning (r=.440, p<.001), and clinical reasoning ability (r=.824, p<.001). Based on these results, integrated simulation practice education for nursing students appears to be an effective educational method for enhancing their self-efficacy in learning, clinical reasoning ability, and clinical performance. To improve nursing students' clinical performance, it is necessary to operate simulation practices with various scenarios.

Analysis of CRLB Performances with CAF under Multiple Emitters (CAF 이용 다중 발기하에서의 CRLB 성능 분석)

  • Lee, Young-kyu;Yang, Sung-hoon;Lee, Chang-bok;Park, Young-Mi;Lee, Moon-Seok
    • Journal of Institute of Control, Robotics and Systems
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    • v.21 no.6
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    • pp.589-594
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    • 2015
  • In this paper, we described the Cramer-Rao Lower Bound (CLRB) performances of Time Difference of Arrival (TDOA) and Frequency Difference of Arrival (FDOA) methods when there are multiple emitters. The TDOA and FDOA values between two receivers can be simultaneously estimated by using the so-called Complex Ambiguity Function (CAF). In the case of multiple emitters, there exist Inter Symbol Interferences (ISIs) in the measurement data. Therefore, it is required to reduce the effect of ISI and provide a performance evaluation method of TDOA and FDOA estimations. In order to eliminate the ISIs, using of a filter bank before calculating CAF is proposed when the carrier frequencies of the emitters are different to one another. Angle of Arrival (AOA) or Received Signal Strength (RSS) methods before calculating CAF were proposed to reduce the ISIs when the carrier frequencies are the same. In order to evaluate the CRLB of TDOA and FDOA estimations, we employed the conditional probability distribution method and described the numerical comparison results.

Bone Mineral Density and Factors influencing Bone Mineral Density in College Women (일 대학 여대생의 골밀도와 골밀도에 영향을 주는 요인)

  • Chon, Mi-Young;Jeon, Hye-Won;Kim, Myoung-Hee
    • Women's Health Nursing
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    • v.18 no.3
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    • pp.190-199
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    • 2012
  • Purpose: The purpose of this study was to identify the levels of bone mineral density (BMD) and to explain the factors influencing BMD among female college students in Korea. Methods: A cross-sectional study was conducted with 144 college women. Lifestyle factors were determined by self-report questionnaire. Body composition was measured by body composition analyzer and bone mineral density was measured by ultrasound bone densitometry. Data were analyzed using SPSS for windows, version 19.0. Results: The mean BMD at calcaneus site was 0.56$g/cm^2$ (mean T-score=-0.22). The incidence of osteopenia was 21.5%. Factors predicting BMD were menarche age (r=-.22, p=.009) and height (r=-.18, p=.030) with 7% of explained variance. Conclusion: These results suggest that health care professionals need to provide young women with program that is intended to affect their intention toward osteoporosis preventive behavior change.

First Record of Two Euplotes Ciliates (Ciliophora: Spirotrichea: Euplotida) from Korea

  • Park, Mi-Hyun;Kim, Se-Joo;Min, Gi-Sik
    • Animal Systematics, Evolution and Diversity
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    • v.26 no.1
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    • pp.21-27
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    • 2010
  • Two marine euplotid ciliates, i.e. Euplotes cristatus Kahl, 1932 and E. minuta Yocom, 1930, were collected from the public waterfront of Incheon on the Yellow Sea and from the Songjeong Beach, Busan, in the Strait of Korea, respectively. These two species were verified as unrecorded species in Korea. These species were described based on live observation, protargol impregnation, and silver nitrate impregnation. In addition, the small subunit ribosomal DNA (SSU rDNA) sequences of the two species were compared with previously known sequences of the Euplotes species. Euplotes cristatus has an elongated oval form, size in vivo of $60-84{\times}38-68\;{\mu}m$, 35-50 adoral zone of membranelles (AZM), 10 frontoventral cirri (FVC), 5 transverse cirri (TC), 4-5 caudal cirri (CC), 8 dorsal kineties (DK), 10-16 dorsal cilia of middle DK, and silverline system of single-vannus type. Euplotes minuta has a small ovoid form ($44-53{\times}26-35\;{\mu}m$ in vivo), 31-41 AZM, 10 FVC, 5 TC, 4 CC, 9 DK, 10-12 dorsal cilia of middle DK, and silverline system of single-vannus type.

Bone Mineral Density, Body Mass Index, Stress, and Health Promotion Lifestyle of Female College Students (일 대학 여대생의 골밀도, 체질량지수, 스트레스 및 건강증진 생활양식)

  • Kim, Chun-Mi;Kim, Eun-Man
    • Research in Community and Public Health Nursing
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    • v.21 no.3
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    • pp.333-340
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    • 2010
  • Purpose: The purpose of this study was to examine the bone mineral density (BMD), body mass index (BMI), stress, and health promotion lifestyle of female college students and to assess relations among them. Methods: A total of 220 female college students were assessed through anthropometric measurements and bone mineral density test using quantitative ultrasound. In addition, the subjects were asked about stress and health promotion lifestyle with a self-rating questionnaire. Collected data were processed with the SPSS/WIN 12.0 program. Results: 1) Of the students, 67.8% had weight control experience. The percentage of the osteoporosis, osteopenia and normal groups were 2.8%, 53.5% and 43.8%, respectively, and the percentage of the underweight, normal and overweight groups according to BMI were 27.9%, 57.2% and 14.9%, respectively. 2) The levels of stress and health promotion lifestyle were 2.9 and 2.3, respectively. 3) There was a positive correlation between BMD and BMI (r=.196, p<.01). There was a negative correlation between stress and health promotion lifestyle (r=-.35, p<.01). 4) Weight control experience made negative effects on BMD and BMI. Conclusion: The findings of this study suggest the necessity of new health promotion programs to increase bone density of female college students. Stress management programs are also needed.

Influence of Perception of Patient rights and Ethical Values on Biomedical Ethics Awareness in Nursing Students (간호대학생의 환자권리에 대한 인식과 윤리적 가치관이 생명의료윤리의식에 미치는 영향)

  • Kim, Mi Sook;Jeon, Min Kyung
    • Journal of East-West Nursing Research
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    • v.24 no.1
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    • pp.1-9
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    • 2018
  • Purpose: The purpose of this study was to identify nursing students' perception of patient rights, their ethical values and biomedical ethics awareness, and to examine the factors affecting the nursing students' biomedical ethics awareness. Methods: The participants of this study were 273 nursing students in B and K metropolitan city. Data collection was conducted through the structured questionnaires from March 2 to March 25, 2016. Data were analyzed using t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, and multiple regression analysis with SPSS WIN v 21.0. Results: The mean scores of nursing students' perception of patient rights, ethical values and biomedical ethics awareness were $4.56{\pm}0.38$, $3.26{\pm}0.31$, $2.91{\pm}0.20$, respectively. Biomedical ethics awareness was positively correlated with the nursing students' perceptions of patient rights (r=.38, p<.001) and ethical values (r=.25, p<.001). Factors affecting the nursing students' biomedical ethics awareness were the perception of patient rights (${\beta}=.36$, p<.001) and ethical values (${\beta}=.13$, p=.023). Conclusion: The results suggest that nursing educational program should include perception of patient rights and ethical values to foster biomedical ethics awareness for nursing students.

Effect of Professional Autonomy, Communication Satisfaction, and Resilience on the Job Satisfaction of Intensive Care Unit Nurses (중환자실 간호사의 전문직자율성, 의사소통만족도, 회복탄력성이 직무만족도에 미치는 영향)

  • Park, Eun Jin;Lee, Yun Mi
    • Journal of Korean Critical Care Nursing
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    • v.11 no.2
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    • pp.63-74
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    • 2018
  • Purpose : This study aimed to identify the factors influencing job satisfaction in intensive care unit (ICU) nurses. Method : Using a cross-sectional design, data collected from 145 ICU nurses working at two university hospitals with more than 1,200 beds located in B and Y city were analyzed. The instruments used for this study assessed autonomy, communication satisfaction, resilience, and job satisfaction. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficient, and multiple linear regression analysis. Results : Job satisfaction was significantly correlated with communication satisfaction (r=.60, p < .001) and resilience (r=.34, p < .001). Further, job satisfaction was influenced by communication satisfaction (${\beta}=.48$, p < .001), working at a surgery ICU (${\beta}=.21$, p =.008), and dissatisfaction with nursing (${\beta}=-.24$, p =.005). The explanatory power of this model was 44.7%. Conclusion : These results suggest the need for programs to improve communication satisfaction and nursing satisfaction.

Knowledge, Performance and Stress about Care for Delirium in Orthopedic Hospital Nurses (정형외과병원 간호사의 섬망간호에 대한 지식, 수행 및 스트레스)

  • Kim, Mi Young;Eun, Young
    • Journal of muscle and joint health
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    • v.20 no.1
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    • pp.72-80
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    • 2013
  • Purpose: This study was conducted to investigate the correlation among nurses' knowledge, performance, and stress about care for delirium. Methods: The data were collected using the instruments for knowledge about nursing care (50 items), performance (23 items), and stress (20 items). Descriptive statistics and Pearson's correlation coefficient were used to analyze the data of 222 participants. Results: Nursing knowledge were different by clinical experience (F=3.12, p=.016), position at work (t=-2.54, p=.012), experience in caring patients with delirium (t=3.90, p<.001), and conflicts with other disciplines on matters related to delirium (t=4.00, p=.001). The difference in performance were associated with age (F=4.19, p=.001), clinical experience (F=2.67, p=.003), and whether there was a guideline for managing the patients with delirium (t=2.30, p=.022). Stress of nurses was different by whether they had a religion or not (t=-2.41, p=.017). The knowledge of care for delirium had the positive relationship with performance (r=.21, p=.001) and negative relationship with stress (r=-.29, p=.001). Conclusion: It is necessary to develop educational program and guideline for improving the knowledge and performance in care for delirium among nurses working at orthopedic hospitals.