• Natural Product Sciences
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• v.15 no.1
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• pp.22-26
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• 2009

Phytochemical investigation of the roots of Echiochilon fruticosum resulted in the isolation of two naphthoquinone derivatives. Compound 1 was identified as anhydroalkanin while compound 2 was identified as a new derivative 5-hydroxy 8-methoxy 2-(4-methylpent-1,3-dienyl) naphthalene-1,4-dione named as echiochiloquinone. In addition, caffeic acid 3, caffeic acid methyl ester 4 were isolated. The structures were determined by physical, chemical and spectral methods. The anti-inflammatory activity of the root extracts and compound 2 was evaluated utilizing both cotton pellet-induced and carragenin-induced rat paw edema. The ulcerogenic effect was also studied.

• Food Science and Biotechnology
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• v.14 no.5
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• pp.656-660
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• 2005

The relationship between the gas chromatographic (GC) patterns of sauce made of barley bran and ranked order in sensory analysis was investigated by multiple regression analysis (MRA). Most of the 42 barley bran sauce samples comprised about 34 peaks, in which the content of 9, 12-octadecanoic acid methyl ester was the highest, followed by those of 2-furanmethanol and 2-furancarboxaldehyde. It is difficult to estimate the aroma quality of barley bran sauce samples on the basis of only one peak. The 34 aroma compounds of the 42 samples were analyzed by an MRA model featuring six transformations. The most precise fit was calculated from the absolute value transformed with the root square of each peak, and the multiple determination coefficient showed that 91.6% of the variation in the sensory score could be explained on the basis of GC data.

• Natural Product Sciences
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• v.17 no.2
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• pp.80-84
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• 2011

Five known compounds, cimigenol (1), 25-O-acetylcimigenol (2), cimigenol 3-O-${\beta}$-D-xylopyranoside (3), ferulic acid methyl ester (4), and visnagin (5), were isolated from Cimicifugae Rhizoma (Ranunculaceae). The chemical structures of these compounds were determined on the basis of spectroscopic analyses including 2D NMR. Compounds 1 - 5 were evaluated for their cytotoxic activity against the HL-60, MCF-7, and A549 cancer cell lines in in vitro. Among them, compounds 4 and 5 showed moderate inhibitory activity against HL-60 cancer cell lines with $IC_{50}$ values of 24.8 and 18.1 ${\mu}M$, respectively.

• Biomolecules & Therapeutics
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• v.8 no.4
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• pp.305-310
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• 2000

The present study examined the effect of a methanol extract of Evodiae Fructus on the blood pressure in spontaneously hypertensive rats (SHR). The systolic blood pressure was measured after rats were pretreated with phentolamine, propranolol, or $N_{\omega}$-nitro-$_{L}$-arginine methyl ester(NAME) and subsequently received methanol extract of Evodiae Fructus. In SHR, intraperitoneal administration of methanol extract of Evodiae Fructus (0.5 mg/kg) produced antihypertensive effect that lasted for at least 4 hours. Antihypertensive effect of Evodiae Fructus was more stronger than that with $\alpha$-adrenergic receptor antagonist phentolamine and was not affected by $\beta$-adrenergic receptor antagonist propranolol. The antihypertensive effect of Evodiae Fructus was abolished by pretreatment of NAME. Our findings suggest Evodiae Fructus has an hypertensive effect, which may be mediated through nitric oxide synthesis.s.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1995.04a
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• pp.111-111
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• 1995

1. 혈압 및 맥박 실험 Acetylcholine과 상엽 수층분획을 단독으로 정맥에 투여한 경우 각각에서 농도 의존적으로 일시적인 혈압 강하 효과가 나타났고 빈맥 현상이 관찰되었다. Nitric Oxide 합성효소 억제제인 N$^{G}$ -Nitro-L-Arginine Methyl Ester(10 mg/kg I. v)를 전처리한 경우 위 두 약물에 의한 혈압강하효과는 공히 증가되어졌다. 또한 두 약물에 의한 혈압강하 효과는 Atropine Sulfate(1 mg/kg i.v) 전처리로 완전히 차단되었다. Cholinesterase 억제제인 Physostigmine (0.05 mg/kg i.v) 전처리는 상엽의 혈압강하 효과에 아무런 영향을 나타내지 못하였다. 2. 장관 실험 Acetylcholine과 상엽 수층분획을 organ bath에 첨가한 경우 각각에서 농도 의존적으로 장관 수축력을 증가시켰다. 혈압반응에서와 같이 장관실험에서도 두 약물에 의한 장관 수축력의 증가는 Atropine Sulfate(1$\times$$10^{-5}$ M)의 존재하에서는 완전히 차단되어졌다. 이상의 결과로부터 상엽 수층분획은 Acetylcholine과 유사한 작용을 지닌 물질을 함유하는 것으로 사료된다.

• New & Renewable Energy
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• v.3 no.2 s.10
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• pp.17-23
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• 2007

대두유로부터 생산된 바이오디젤과 바이오디젤 혼합 연료유를 대상으로 지방산메틸에스터 함량과 화학적 분석을 통해 산화 특성과 오일의 수명 예측 연구를 수행하였다. 바이오디젤, 경유, BD5, BD20은 산화가 진행될수록 산가(Acid number), 동점도(Kinematic Viscosity) 및 밀도(Density)는 증가하였다. 산가 측정결과의 활용에 의해 임의의 온도조건에서 정확한 사용수명을 예측하기 위하여 화학속도론에 의거하여 각각의 연료에 대한 사용수명식을 도출하였다. 도출된 사용수명식으로부터 바이오디젤이 가장 빠르게 산화가 진행되었고 바이오디젤 혼합량이 증가할수록 사용수명이 단축되는 것을 확인할 수 있었다.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.387-387
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• 2011

ITO (Indium-Tin Oxide)는 전기전도도, 가시광선투과도가 높으며, 패터닝하기 쉬운 장점을 가지나 Indium의 자원 고갈에 의한 재료비 상승의 문제점을 가지고 있어, 이를 대체하기 위한 연구가 진행되고 있다. 본 연구에서는 ITO 대신 AZO (ZnO:Al)를 기판온도에 따라 마그네트론 DC 스퍼터를 이용하여 소다라임 글래스에 증착하여 투명전극의 전기, 광학적 특성을 분석하였다. 조건에 따라 증착된 AZO 투명전극위에 유기 태양전지 흡수층으로 Poly (3-hexylthiophene) (P3HT)와 (phenyl-C61-butyric acid methyl ester (PCBM)를 사용하였으며, Glass/AZO/P3HT:PCBM/PEDOT:PSS/Ag의 구조를 갖는 Inverted 유기 태양전지를 제작하여 ITO 투명전극에 제작된 유기태양전지와의 특성을 비교, 분석 하였다.

• Textile Coloration and Finishing
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• v.26 no.3
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• pp.272-276
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• 2014

The functional materials have been developed as a promising research topic toward the end uses for organic materials and applications. In this study, fluorescein based dye was synthesized by three step reaction. We have designed and synthesized the colorimetric dye through the reactions of fluorescein and methoxy group and ethylene diamine and squaric acid. The structure of the non-fluorescent spirolactam was elucidated by $^1H$-NMR, LC-Mass and FT-IR analyzes. Further studies are in progress to understand the effects of various substituent during the recognition process and to develop fluorescein based sensors for cations or anions.

• Journal of Food Hygiene and Safety
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• v.9 no.2
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• pp.89-94
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• 1994

A simple, safe, and sensitive gas chromatographic method using packed column and electron capture detector to analyze 2, 4-D herbicide in imported lemon, grapefruit, and orange was described and its usefulness evaluated. In this scheme of analysis the acid herbicide was converted into its alkyl esters by an one-step reaction prior to analysis. The herbicide in the fruits was extracted with ethyl acetate and partitioned against dichloromethane for purification, and the extracts finished partitioning were derivatized with alcohol, using sulfuric acid as a catalyst to form the corresponding alkyl derivatives. The analytical scheme studiedwas found to be applicable for the herbicide in the fruits without a column clean-up procedure. The mean recoveries of the herbicide for lemon samples fortified at 0.1 mg/kg and 1.0 mg/kg were 93% and 95%, respectively. The detection limit was 0.5 $\mu\textrm{g}$/kg for 2.4-D methyl ester.

• Archives of Pharmacal Research
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• v.28 no.10
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• pp.1156-1160
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• 2005

An iridoid glycoside, oldenlandoside III (5) was isolated from the n-butanol fraction of methanol extracts of the aerial parts of Oldenlandia diffusa Roxb. along with six others previously characterized iridoid glycosides; geniposidic acid (1), scandoside (2), feretoside (3), 10-O-ben-zoylscandoside methyl ester (4), asperulosidic acid (6) and deacetylasperulosidic acid (7). Compounds 1, 2, and 7 inhibited LDL-oxidation, and showed $63.3{\pm}2.0,\;62.2{\pm}1.6,\;and\;63.8{\pm}1.5\%$ inhibition, respectively, at a concentration of 20 ${\mu}g/mL$.