• Title/Summary/Keyword: methods and techniques

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Trend of In Silico Prediction Research Using Adverse Outcome Pathway (독성발현경로(Adverse Outcome Pathway)를 활용한 In Silico 예측기술 연구동향 분석)

  • Sujin Lee;Jongseo Park;Sunmi Kim;Myungwon Seo
    • Journal of Environmental Health Sciences
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    • v.50 no.2
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    • pp.113-124
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    • 2024
  • Background: The increasing need to minimize animal testing has sparked interest in alternative methods with more humane, cost-effective, and time-saving attributes. In particular, in silico-based computational toxicology is gaining prominence. Adverse outcome pathway (AOP) is a biological map depicting toxicological mechanisms, composed of molecular initiating events (MIEs), key events (KEs), and adverse outcomes (AOs). To understand toxicological mechanisms, predictive models are essential for AOP components in computational toxicology, including molecular structures. Objectives: This study reviewed the literature and investigated previous research cases related to AOP and in silico methodologies. We describe the results obtained from the analysis, including predictive techniques and approaches that can be used for future in silico-based alternative methods to animal testing using AOP. Methods: We analyzed in silico methods and databases used in the literature to identify trends in research on in silico prediction models. Results: We reviewed 26 studies related to AOP and in silico methodologies. The ToxCast/Tox21 database was commonly used for toxicity studies, and MIE was the most frequently used predictive factor among the AOP components. Machine learning was most widely used among prediction techniques, and various in silico methods, such as deep learning, molecular docking, and molecular dynamics, were also utilized. Conclusions: We analyzed the current research trends regarding in silico-based alternative methods for animal testing using AOPs. Developing predictive techniques that reflect toxicological mechanisms will be essential to replace animal testing with in silico methods. In the future, since the applicability of various predictive techniques is increasing, it will be necessary to continue monitoring the trend of predictive techniques and in silico-based approaches.

Intelligent Marketing and Merchandising Techniques for an Internet Shopping Mall (인터넷 쇼핑몰에서의 지능화된 마케팅과 상품화 계획 기법)

  • Ha, Sung-Ho;Park, Sang-Chan
    • Asia pacific journal of information systems
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    • v.12 no.3
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    • pp.71-88
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    • 2002
  • In this paper, intelligent marketing and merchandising methods utilizing data mining and Web mining techniques are proposed for online retailers to survive and succeed in gaining competitive advantage in a highly competitive environment. The first part of this paper explains the procedures of one-to-one marketing based on customer relationship management(CRM) techniques and personalized recommendation lists generation. The second part illustrates Web merchandising methods utilizing data mining techniques, such as association and sequential pattern mining. We expect that our Web marketing and merchandising methods will both provide a currently operating Internet shopping mall with more selling opportunities and give more useful product information to customers.

The Comparison of Singular Value Decomposition and Spectral Decomposition

  • Shin, Yang-Gyu
    • Journal of the Korean Data and Information Science Society
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    • v.18 no.4
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    • pp.1135-1143
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    • 2007
  • The singular value decomposition and the spectral decomposition are the useful methods in the area of matrix computation for multivariate techniques such as principal component analysis and multidimensional scaling. These techniques aim to find a simpler geometric structure for the data points. The singular value decomposition and the spectral decomposition are the methods being used in these techniques for this purpose. In this paper, the singular value decomposition and the spectral decomposition are compared.

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Classification Methods for Fault Diagnosis of an Air Handling Unit (공조 시스템의 고장진단을 위한 분류기술 연구)

  • Lee, Won-Yong;Shin, Dong-Ryul;House, John M.
    • Proceedings of the KIEE Conference
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    • 1998.07b
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    • pp.420-422
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    • 1998
  • All Fault Detection and Diagnosis(FDD) methods utilize classification techniques. The objective of this study was to demonstrate the application of classification techniques to the problem of diagnosing faults in data generated by a variable-air-volume(VAV) air-handling unit(AHU) simulation model and to describe the characteristics of the techniques considered. Artificial neural network classifier and fuzzy clustering classifier were considered for fault diagnostics.

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Ultrafine Particle Toxicities, Current Measurement Techniques and Controls (Ultrafine Particle의 독성, 측정방법 및 관리)

  • Lee, Su-Gil;Kim, Seong-Soo
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.3
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    • pp.203-215
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    • 2010
  • This study is an overview of toxicities and measurement techniques of ultrafine particles (UFPs), and their exposure controls. UFPs are ubiquitous in many working situations. Exposure to UFPs is possibly causing adverse health symptoms including cardio-respiratory disease to humans. In order to measure exposure levels of airborne UFPs, there are current available measurement guidelines, instruments and other techniques (i.e. contour mapping, control banding). However, these risk assessment techniques including measurement techniques, controls and guidelines are dependent on background levels, metrics (e.g. size, mass, number, surface area, composition), environmental conditions and controls. There are no standardized measurement methods available and no generic and specific occupational exposure standards for UFPs. It is thought that there needs to be more effort to develop Regulations and Exposure Standards for generic UFPs should be based on more exposure data, health surveys, toxicological data and epidemiological data. A carefully considered hierarchy of controls can also reduce the maximum amount of airborne UFPs being emitted from diverse sources in industries.

A Study on the Development of Measurement Techniques for Thermal Flows in MEMS

  • Ko Han-Seo;Yang Sang-Sik;Yoo Jai-Suk;Kim Hyun-Jung
    • Journal of Electrical Engineering and Technology
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    • v.1 no.3
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    • pp.387-395
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    • 2006
  • A review on advanced flow visualization techniques is presented particularly for applications to micro scale heat and mass transport measurements. Challenges, development and applications of micro scale visualization techniques are discussed for the study of heating/evaporating thin films, a heated micro channel, and a thermopneumatic micro pump. The developed methods are (1) Molecular Tagging Fluorescence Velocimetry (MTFV) using 10-nm caged seeding molecules (2) Micro Particle Velocimetry (MPIV) and (3) Ratiometric Laser Induced Fluorescence (LIF) for micro-resolution thermometry. These three methods are totally non-intrusive techniques and would be useful to investigate the temperature and flow characteristics in MEMS. Each of these techniques is discussed in three-fold: (1) its operating principle and operation, (2) its application and measurement results, and (3) its future challenges.

The Effects of PNF Techniques on Lymphoma in the Upper Limbs (상지의 림프종에 적용한 PNF 기법의 효과)

  • Kim, Dae-Kyeong;Ha, Kyung-Jin
    • PNF and Movement
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    • v.10 no.2
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    • pp.1-8
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    • 2012
  • Purpose : The purpose of study was aimed to identify whether the painless dynamic PNF techniques makes any differences in reducing lymphedema by applying this technique to lymphedema patients, and to provide the basic reference data for the purpose of applying to lymphedema patients. Methods : A total of 40 women participated in this study, and they did PNF techniques before applying lymph compression bandages. Group 1 of 20 subjects performed PNF techniques three times a week with 30 minutes each time. Group 2 of 20 subjects only practiced edema reducing massaging for 30 minutes. Results : In addition, the interaction between treatment method and treatment time was significant (p<.0001), which indicates that the changes in edema rates by measurement times appear differently according to treatment methods. In this study, it means that the 'PNF techniques' group has a steeper slope of decline than the 'message' group. Conclusion : In conclusion, both massaging and PNF techniques helped to lower edema rates. Four weeks after the beginning of treatment, PNF techniques was exhibited as generating a large degree of decline in edema rates than massaging.

Raman Chemical Imaging Technology for Food and Agricultural Applications

  • Qin, Jianwei;Kim, Moon S.;Chao, Kuanglin;Cho, Byoung-Kwan
    • Journal of Biosystems Engineering
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    • v.42 no.3
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    • pp.170-189
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    • 2017
  • Purpose: This paper presents Raman chemical imaging technology for inspecting food and agricultural products. Methods The paper puts emphasis on introducing and demonstrating Raman imaging techniques for practical uses in food analysis. Results & Conclusions: The main topics include Raman scattering principles, Raman spectroscopy measurement techniques (e.g., backscattering Raman spectroscopy, transmission Raman spectroscopy, and spatially offset Raman spectroscopy), Raman image acquisition methods (i.e., point-scan, line-scan, and area-scan methods), Raman imaging instruments (e.g., excitation sources, wavelength separation devices, detectors, imaging systems, and calibration methods), and Raman image processing and analysis techniques (e.g., fluorescence correction, mixture analysis, target identification, spatial mapping, and quantitative analysis). Raman chemical imaging applications for food safety and quality evaluation are also reviewed.

State of the Art of Anti-Screen Capture Protection Techniques

  • Lee, Young;Hahn, SangGeun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.15 no.5
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    • pp.1871-1890
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    • 2021
  • The transition toward a contactless society has been rapidly progressing owing to the recent COVID-19 pandemic. As a result, the IT environment of organizations and enterprises is changing rapidly; in particular, data security is expanding to the private sector. To adapt to these changes, organizations and companies have started to securely transfer confidential data to residential PCs and personally owned devices of employees working from home or from other locations. Therefore, organizations and companies are introducing streaming data services, such as the virtual desktop infrastructure (VDI) or cloud services, to securely connect internal and external networks. These methods have the advantage of providing data without the need to download to a third terminal; however, while the data are being streamed, attacks such as screen shooting or capturing are performed. Therefore, there is an increasing interest in prevention techniques against screen capture threats that may occur in a contactless environment. In this study, we analyze possible screen capture methods in a PC and a mobile phone environment and present techniques that can protect the screens against specific attack methods. The detection and defense for screen capture of PC applications on Windows OS and Mac OS could be solved with a single agent using our proposed techniques. Screen capture of mobile devices can be prevented by applying our proposed techniques on Android and iOS.

A Study on the Characteristics of the Manufacturing Method of Handbags by Brand

  • Youshin Park
    • Journal of Fashion Business
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    • v.27 no.6
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    • pp.66-84
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    • 2023
  • Handbags are a part of fashion and while their significance and value are increasing, research on this topic is lacking. This study defines handbags and categorizes the materials used for making handbags, sewing methods, expression techniques, and terminologies related to accessories. A total of 1,743 handbags that were released from the Spring 2020 to Fall 2023, Ready-to-Wear collections by 8 selected brands (Hermes, Dior, Fendi, Chanel, Louis Vuitton, Prada, Gucci, and Alexander McQueen), were analyzed. Out of these, 732 unique designs, excluding those with only color variations, were studied. The most common sewing methods were 'Cut, sewing, and edge painting', 'Cylinder arm sewing', 'Cut, edge painting, and sewing', and 'Inverted seam', in that order. Slim strap designs primarily used the 'Cut, sewing, and edge painting' method, whereas the body, especially with narrow and hard leather, was best suited for the 'Cylinder arm sewing machine'. For expression techniques, the most frequently used methods were 'Quilting', 'Metal Eyelet', 'Embossing', 'Printing', 'Punching', and 'Weaving', respectively. The characteristics of each brand's production methods, expression techniques, and accessories were as follows: First, the exposure of logos and monograms is prominent. Unlike clothing, handbags often prominently feature the brand's logo or monogram. Second, signature quilting is a prominent feature. Quilting effectively conveys the brand's signature style, providing cushioning, volume, and pattern effects. Third, sustainable development is a growing trend. Brands are increasingly applying eco-friendly and socially responsible designs.