• Title, Summary, Keyword: metabolic risk

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The Relationship between Metabolic Syndrome and Korean Cardiocerebrovascular Risk Assessment: for Male Researchers in a Workplace (대사증후군과 뇌심혈관질환 발병위험도 평가와의 연관성: 일개 사업장 남성 근로자를 대상으로)

  • Yoon, Jong-Wan;Yi, Kyung-Jin;Lee, Sang-Yun;Oh, Jang-Gyun
    • Journal of Preventive Medicine and Public Health
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    • v.40 no.5
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    • pp.397-403
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    • 2007
  • Objectives: The prevalence of metabolic syndrome has recently increased, Payments from the Korea Labor Welfare Corporation for compensation for mortality in workers caused by cardiovascular and cerebrovascular diseases have also increased in Korea in recent years. The association of metabolic syndrome and cardiocerebrovascular disease has been investigated by several researchers in recent studies, This study was conducted in an attempt to characterize the relationship between metabolic syndrome and Korean cardiocerebrovascular disease risk assessment, and to provide basic data to group health practices for the prevention of cardiocerebrovascular disease. Methods: Health examinations were previously conducted for 1526 male researchers at a private laboratory. The prevalence by age and the odds ratio of metabolic syndrome scores into the "cardiocerebrovascular risk group" (sum of low, intermediate, and high risk groups) of the Korean cardiocerebrovascular disease risk assessment were assessed, in an effort to elucidate the associations between metabolic syndrome and cardiocere brovascular disease risk assessment. Results: The prevalence of metabolic syndrome and inclusion in the cardiocerebrovascular risk group was 11,7% and 22.1% respectively. The severity of metabolic syndrome and cardiocerebrovascular risk assessment showed that individuals in their 40's and 50's were at higher risk than those in their 30's (p<0,001). The age-adjusted odds ratio of metabolic syndrome to cardiocere brovascular risk group inclusion was 5.6. Conclusions: An active prevention program for cardiocerebrovascular disease needs to begin in the 40's, as the prevalence of metabolic syndrome and the risk group of cardiocerebrovascular risk assessment peak in the 40's age group. The odds ratio between metabolic syndrome and the cardiocerebrovascular risk group was high, which indicates that metabolic syndrome scores should be utilized as guidelines during the consultation and behavioral modification program for the workplace prevention of cardiocerebrovascular diseases in group health practices.

The Association between hs-CRP Concentration of Blood and Metabolic Syndrome in the Residents of a Rural Community (일부 농촌지역 주민들의 혈중 hs-CRP 농도와 대사증후군 위험인자와의 관계)

  • Kim, Jong-Im
    • Korean Journal of Community Nutrition
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    • v.15 no.6
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    • pp.796-805
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    • 2010
  • This study investigated the correlations and risk distribution differences between high sensitivity C-reactive protein (hs-CRP) and the diagnosis factors of metabolic syndrome among the residents of a rural community. Two thousand adults aged from 40 to 70 were recruited and 1,968 subjects were included in the study after excluding those with infectious disease or with hs-CRP higher than 10 mg/L in blood. The subjects were then divided into three groups of hs-CRP to examine the correlations and risk ratio with the risk factors of metabolic syndrome. There was a tendency of hs-CRP increasing according to the number of risk factors of metabolic syndrome. The risk ratio with hs-CRP according to metabolic syndrome significantly increased by 2.0 and 2.2 times in the intermediate and high risk group, respectively, compared with the low risk group. The risk ratio with the risk factors of metabolic syndrome according to hs-CRP rose in abdominal obesity, triglyceride, and W/Ht in the intermediate risk group of hs-CRP. The risk ratio also surged in high pressure, W/Ht, ex-drinking (1.7 times), exsmoking (2.0 times) and current smoking (2.0 times) in the high risk group. The results indicate that hs-CRP is related to the risk factors of metabolic syndrome and that it's very important to manage obesity including abdominal obesity and W/Ht and everyday habits including drinking and smoking.

Factors Affecting Metabolic Syndrome in a Rural Community (한 농촌지역 주민들의 대사증후군 관련요인)

  • Kim, Jong-Im
    • Korean Journal of Health Education and Promotion
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    • v.26 no.1
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    • pp.81-92
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    • 2009
  • Objectives: This study set out to investigate the relationship among the factors of metabolic syndrome diagnosis criteria, their risk factors including general characteristics, and the distribution of the diagnosis criteria and risk among the adult residents of a rural community. Methods: Among 1,968 residents, those who had three or more of the risk factors of metabolic syndrome, which include blood pressure, blood glucose, triglyceride, abdominal obesity, and HDL-C, were categorized as the metabolic syndrome group. And their correlations were analyzed. Results: As for the risk ratio with five factors of the metabolic syndrome diagnosis criteria, it was high according to age and smoking. In addition, the results show that body fat percentage, hs-CRP, insulin, BMI, PP2, total cholesterol, and W/Ht also had much impact on increasing the risk ratio of the metabolic syndrome diagnosis criteria. It turned out that metabolic syndrome was affected by the body mass index(BMI), insulin, waist to height ratio(W/Ht), and hs-CRP. It was 2.51 times crude odds ratio that BMI over the 25kg/m2 in the ratio of the fact of metabolic syndrome and adjusted for sex odds ratio 2.50times and W/Ht was 3.31times, adjusted for sex odds ratio 3.25 times. Conclusion: BMI, W/Ht and smoking of the general characteristics seem to have close relationships with high correlations between the metabolic syndrome diagnosis criteria and the risk factors. Thus there is an urgent need to evaluate them and take interventions and monitoring measures for the clustering of risk factors.

Prevalence Rates and Risk Factors of Metabolic Disorder in Urban Adults assessed in Home Visits (가정방문을 통한 일 광역시 성인의 대사증후군 유병률 및 위험요인 조사)

  • Kim, Jong-Im
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.16 no.1
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    • pp.12-21
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    • 2009
  • Purpose: The survey-based study aimed to determine the distribution and clustering tendency of metabolic syndrome risk factors in urban residents, and cluster odds ratios. Methods: Cluster sampling involved 827 urban participants and analysis of the collected data. Results: Regarding the prevalence of metabolic syndrome risk factors used for diagnosis, abdominal obesity was higher in women(69.5%) than in men(34.3%), high blood pressure was higher in men(57%) than in women(46.5%), and blood sugar was higher in men(6.9%) than in women(5.7%). Clustering increased with increasing body mass index(BMI), weight:height ratio(W/Ht) and abdominal obesity Risk factors for females were 1.7 times higher than for males. Participants with a family history of metabolic syndrome displayed related risk factors 1.5 times more than participants without a family history. Participants having a BMI ranking them as obese were 9.5 times more likely to display metabolic syndrome risk factors than non-obese participants. Obese participants were 20 times more likely to display risk factors than non-obese participants. Conclusion: BMI, W/Ht and abdominal obesity correlate with clustering of metabolic syndrome risk factors. The risk is increased by smoking and family history. Exercise weight control and non-smoking are recommended for comprehensive management of clustering of metabolic syndrome risk factors.

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Comparison of oral health status by metabolic syndrome risk factors in workers (일부지역 근로자의 대사증후군 위험요인별 분류와 구강건강상태 비교)

  • Ku, In-Young;Moon, Seon-Jeong;Lee, Myeong-Seon;Ka, Kyung-Hwan
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.4
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    • pp.581-588
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    • 2013
  • Objectives : The aim of the study si to investigate correlation between metabolic syndrome risk factors and oral health status in workers and to propose the integrated and effective management measures. Methods : Subjects were 4,600 workers in industrial company. Data by medical checkup and oral examination were collected from July 13, 2010 to September 12, 2010. Self-reported questionnaire included general characteristics, job description, smoking, drinking, and metabolic syndrome risk factor indicators. Gingivitis, dental calculus and missing tooth tended to have more metabolic syndrome risk factors. Data were analyzed by descriptive statistics, chi-square test, correlation analysis, logistic regression using SPSS version 18.0. Results : Dental caries revealed 1.146 times higher than the control group. Risk group showed the following results; gingivitis was 1.317 times higher in risk group and 1.612 times in metabolic syndrome. Dental calculus was 1.532 times higher in risk group and 1.557 times in metabolic syndrome. Mssing teeth were 1.976 higher in metabolic syndrome. Conclusions : Metabolic syndrome risk factors had close correlation to poor raol health status. It is necessary to establish the effective plan for the oral health in workers.

Associations between Sarcopenia and Metabolic Risk Factors: A Systematic Review and Meta-Analysis

  • Du, Yang;Oh, Chorong;No, Jaekyung
    • Journal of Obesity & Metabolic Syndrome
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    • v.27 no.3
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    • pp.175-185
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    • 2018
  • Background: Metabolic risk factors can impact sarcopenia, but the direct relationship of metabolic risk factors with sarcopenia has not been examined. Our purpose was to investigate the effects of metabolic risk factors on sarcopenia in older adults. Methods: Sixteen studies were found through a search of electronic databases and were subjected to a meta-analysis to investigate the differences in metabolic risk factors between patients with sarcopenia and controls. The random-effects standardized mean difference ${\pm}95%$ confidence interval was calculated as the effect size. Results: The results showed that body mass index (BMI), fasting glucose, systolic blood pressure (SBP), diastolic blood pressure (DBP), triglycerides (TG), homeostasis model assessment of insulin resistance (HOMA-IR), high-density lipoprotein cholesterol (HDL-C), and total cholesterol (d=3.252, d=2.039, d=2.956, d=2.579, d=2.123, d=1.195, d=-0.991, and d=1.007, respectively) all had relationships with sarcopenia. In addition, the effect sizes of all male groups for all variables were higher than those of the female groups. However, only the between-sex effect size of HOMA-IR (P<0.01) was significant, while those for BMI, fasting glucose, SBP, DBP, TG, HDL-C, low-density lipoprotein cholesterol, and total cholesterol were not. Finally, the metabolic risk factors appeared to be significantly related to loss of skeletal muscle. Conclusion: Nutrition and appropriate exercise to enhance muscle strength and quality in the elderly reduce the occurrence of sarcopenia, thereby reducing the incidence of metabolic diseases.

Association between Metabolic Syndrome and Physical Fitness in Postmenopausal Women

  • Ku, Min-Ju;Shin, Kyung-A;Ko, Kwang-Jun;Oh, Jae-Keun
    • Biomedical Science Letters
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    • v.18 no.1
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    • pp.63-70
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    • 2012
  • The research is performed in order to know the relationship between the metabolic syndrome and the physical fitness targeted for menopausal women (over 45 years). All subjects were divided into 4 groups; group without risk factors of metabolic syndrome (MS-0: n=74), group having one risk factor of metabolic syndrome (MS-1: n=68), group having two risk factors of metabolic syndrome (MS-2: n=44), and group having more than three risk factors of metabolic syndrome (MS ${\geq}$ 3: n=30). All groups' height, weight, body mass index and percent of body fat were measured. High density lipoprotein cholesterol (HDL), triglyceride, glucose and blood pressure (BP) levels were measured. Their cardiorespiratory ($VO_2max$) endurance, muscular strength, muscle endurance, and flexibility were measured. HDL, triglyceride, glucose and BP levels in MS-1, MS-2, and MS ${\geq}$ 3 group were significantly greater than those of MS-0 group. The endurance ($VO_2max$) in MS ${\geq}$ 3 group was higher than that of MS-0 group. Multiple regression with the risk factors of metabolic syndrome and the physical fitness showed a statistical significance in only $VO_2max$. We found that the risk factors of the metabolic syndrome adversely affect postmenopausal women's $VO_2max$ and that a decreased $VO_2max$ may have prognostic value for the prediction of metabolic syndrome.

Metabolic Risk Profile and Cancer in Korean Men and Women

  • Ko, Seulki;Yoon, Seok-Jun;Kim, Dongwoo;Kim, A-Rim;Kim, Eun-Jung;Seo, Hye-Young
    • Journal of Preventive Medicine and Public Health
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    • v.49 no.3
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    • pp.143-152
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    • 2016
  • Objectives: Metabolic syndrome is a cluster of risk factors for type 2 diabetes mellitus and cardiovascular disease. Associations between metabolic syndrome and several types of cancer have recently been documented. Methods: We analyzed the sample cohort data from the Korean National Health Insurance Service from 2002, with a follow-up period extending to 2013. The cohort data included 99 565 individuals who participated in the health examination program and whose data were therefore present in the cohort database. The metabolic risk profile of each participant was assessed based on obesity, high serum glucose and total cholesterol levels, and high blood pressure. The occurrence of cancer was identified using Korean National Health Insurance claims data. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards models, adjusting for age group, smoking status, alcohol intake, and regular exercise. Results: A total of 5937 cases of cancer occurred during a mean follow-up period of 10.4 years. In men with a high-risk metabolic profile, the risk of colon cancer was elevated (HR, 1.40; 95% CI, 1.14 to 1.71). In women, a high-risk metabolic profile was associated with a significantly increased risk of gallbladder and biliary tract cancer (HR, 2.05; 95% CI, 1.24 to 3.42). Non-significantly increased risks were observed in men for pharynx, larynx, rectum, and kidney cancer, and in women for colon, liver, breast, and ovarian cancer. Conclusions: The findings of this study support the previously suggested association between metabolic syndrome and the risk of several cancers. A high-risk metabolic profile may be an important risk factor for colon cancer in Korean men and gallbladder and biliary tract cancer in Korean women.

Gender difference in the association of metabolic syndrome with hs-CRP Concentration of Blood

  • Park, Se-Kwon
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.2
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    • pp.86-96
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    • 2012
  • The high sensitivity C-reactive protein (hs-CRP) as one of the typical acute phase reactants is used for predictive factor of the cardiovascular disease and diabetes mellitus. In addition, there are claims that must be included as factors of metabolic syndrome. This research examined the relationship between the concentration of hs-CRP in blood and risk factors of the metabolic syndrome by gender, and the rates of metabolic syndrome depending on the hs-CRP level based on the general public who took the comprehensive medical check-up at Chonbuk National University Hospital in the Jeonbuk province. The subjects aged 17-87 years were participated, and 2,000 people were included as the final subjects except the persons with more than 10 mg/L of the hs-CRP of blood level. The hs-CRP concentrations increased according to the number of risk factors of metabolic syndrome in both men and women. In regards to the risk ratio of metabolic syndrome based on hs-CRP level in blood according to gender, the risk ratio increased by 3.07 times in male and 4.55 times in female intermediate risk group and 3.60 times in male and 6.15 times in female high risk group compared to hs-CRP low risk group. As a result, there was a proportional relation between hs-CRP level and the occurrence of metabolic syndrome, and it occurs more frequently among women than men.

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Relation of serum total antioxidant status with metabolic risk factors in Korean adults

  • Kwak, Ho-Kyung;Yoon, Sun
    • Nutrition Research and Practice
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    • v.1 no.4
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    • pp.335-340
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    • 2007
  • The purpose of the present study was to examine the relation of total antioxidant status (TAS) to metabolic risk factors in Korean adults. Anthropometric measures, blood pressure, serum lipids and fasting glucose were determined in 406 men and women. TAS was measured by using commercially available Randox kit. Serum TAS was significantly positively correlated with body weight (p=0.004), body mass index (BMI) (p=0.033), waist circumference (p=0.017), total cholesterol (p=0.038) and triglyceride (TG) (p<0.001). The mean TAS of hypertriglyceridemic subjects (TG ${\geq}$150 mg/dl) was significantly higher than that of subjects whose TG was lower than 150 mg/dl (p=0.001). When central obesity, TG, high density lipoprotein cholesterol, fasting glucose and blood pressure were considered as metabolic risk factors, TAS was shown to be elevated with increased number of metabolic risk factors (p=0.004). The positive association between TAS and a number of metabolic risk factors suggests that increased TAS may not always indicate one's healthier condition. In order to help understand TAS as a marker of total antioxidant capacity in humans with various metabolic conditions, it is needed to clarify the factors affecting TAS in relation to changes in metabolic risk factors.