• Title/Summary/Keyword: metabolic heat

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Ethanol Extract of Ulmus pumila Ameliorates Heat Stress through the Induction of Heat Shock Proteins Expression in RAW264.7 Macrophage Cells

  • dela Cruz, Joseph;Byambaragchaa, Munkhzaya;Choi, Seok-Geun;Hwang, Seong-Gu
    • Journal of Animal Environmental Science
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    • v.20 no.4
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    • pp.147-154
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    • 2014
  • Heat stress is a significant burden to animal production in most areas of the world. Improving our knowledge of physiological and metabolic mechanisms of acclimation may contribute to the development of procedures that may help to maintain health and production efficiency under hot temperature. The effect of Ulmus pumila (UP) extract in inducing Heat Shock Proteins (HSPs) expression in heat-stressed RAW264.7 macrophage cells was investigated. Cell viability assay showed a dose dependent increase in cells after treatment with UP for 24 hours. RT-PCR and western blot analysis showed that increasing concentrations of UP induce the expression of Heat Shock Factor 1 (HSF1) and dose dependently upregulated the expression of Heat shock protein 70 (Hsp70) and Hsp90. LPS-induced nitric oxide was dose-dependently reduced while phagocytic activity greatly recovered with UP treatment. These data demonstrated that UP can be a potential candidate in the development of cytoprotective agent against heat stress.

Computer Simulation for Calculation of Thermal Insulation in Korean Folk Clothes (한복의 보온력 평가를 위한 컴퓨터 시뮬레이션)

  • 권오경;성수광
    • Journal of the Korean Society of Clothing and Textiles
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    • v.21 no.7
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    • pp.1153-1161
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    • 1997
  • The insulation provided by clothing system is usually expressed in terms of a coo units and its distribution of the body, directly affect convective, conductive, and radiant heat loss from the skin to the environment Evaporated heat loss is dependent upon fabric permeability, the amount of body surface area covered by clothing, and the pumping of air between the body and garment layers. Persons at low to medium activity levels, dressed in conventional apparel in door environments, usually do not lose a large amount of heat through evaporation. Thermal manikin technology is used to measure the resistance to heat transfer provided by clothing systems. The reciprocal of this value, 6.45 W/m2.$^{\circ}C$ is often used in calculations for convenience. The purpose of this study was to implement a research program for calculation the insulation value (clo), body surface area and basal metabolic rate of selected clothing system. The project provided for the building of an insulation data base for use in evaluating and comparing new and improved garments.

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Cow Residual Feed Intake(RFI) monitoring and metabolic abnormality prediction system using wearable device for Milk cow and Beef

  • Chang, Jin-Wook;Kwak, Ho-Young
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.10
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    • pp.139-145
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    • 2021
  • In this paper, by using the cattle feed intake, rumination, and in heat monitoring technology, RFI (Residual Feed Intake) monitoring and wearable devices and PCs for predicting abnormalities in budding target web and smart A monitoring system using a phone application was designed and implemented. With the development of this system, the farmer is expected to increase economic efficiency. By analyzing the feed intake, it is possible to identify the difference between the recommended feed amount based on the cow's weight and the feed amount consumed by the cow, and it is expected that early detection of metabolic disorders (abnormality of metabolism) is possible. Farmers using the results of this thesis can distinguish the cows with the most efficient performance, and the 6-axis motion sensor signals input from the wearable device attached to the cow's skin (neck) and the microphone attached to the wearable device. It is possible to measure the cow's rumination and feed intake through the sound of the cow's throat. In the future, improvements will be made to measure additional vital signs such as heart rate and respiration.

Analysis of Poly(3-Hydroxybutyrate) Granule-Associated Proteome in Recombinant Escherichia coli

  • Han Mee-Jung;Park Si-Jae;Lee Jeong-Wook;Min Byoung-Hoon;Lee Sang-Yup;Kim Soo-Jin;Yoo Jong-Shin
    • Journal of Microbiology and Biotechnology
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    • v.16 no.6
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    • pp.901-910
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    • 2006
  • Poly(3-hydroxybutyrate) [P(3HB)] is a microbial polyester intracellularly accumulated as distinct granules in numerous microorganisms as an energy and carbon storage material. Recombinant Escherichia coli harboring the heterologous P(3HB) biosynthesis genes accumulates large amounts of P(3HB) granules, yet the granule-associated proteins have not been identified. Therefore, this study reports on an analysis of the P(3HB) granule-associated proteome in recombinant E. coli. Fiye proteins out of 7 spots identified were found to be involved in functions of translation, heat-stress responses, and P(3HB) biosynthesis. Two of the major granule-associated proteins, IbpA/B, which are already known to bind to recombinant proteins forming inclusion bodies in E. coli, were further analyzed. Immunoblotting and immunoelectron microscopic studies with IbpA/B antibodies clearly demonstrated the binding and localization of IbpA/B to P(3HB) granules. IbpA/B seemed to play an important role in recombinant E. coli producing P(3HB) by stabilizing the interface between the hydrophobic P(3HB) granules and the hydrophilic cytoplasm. Thus, IbpA/B were found to act like phasins in recombinant E. coli, as they are the major proteins bound to the P(3HB) granules, affect the morphology of the granules, and reduce the amount of cytosolic proteins bound to the P(3HB) granules.

Consideration of the Exterior Syndrome Caused And Therpeutical Methods by Warm Heat Pathogen (온열사(溫熱邪)의 의한 외감표증(外感表證)의 발생기전(發生機轉)과 치법(治法)에 대한 소고)

  • Lee, Sang Ryong;Lee, Chang Hyun;Lee, Kwang Gye;Kim, Jun Ho
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.577-587
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    • 2012
  • Warm disease: Any of various heat disease characterizer by rapid onset and shifts, pronounced heat signs, and a tendency to form dryness and damage yin. Exterior heat sign: exterior heat patterns are characterizer by pronounced heat signs, such as a red sore pharynx and a relatively red tongue with dry fur, the pulse is floating and rapid, cough and the production of thick white or yellow phlegm. If wind-heat evil exist in weifen, it becomes exterior syndrome, and a remedy about that is dispelling wind-heat but when wind-heat evil invades in nasal and throat part so the disease occurs, you need to add relieving sore throat worsens invades in lung it makes disharmony of diffuse in lungs. So a remedy about it is diffuse the lung. disharmony of diffuse in lungs makes metabolic disorder of qi and liquid and humor malfunction therefore it occurs cough and heat-phlegm syndrome. heat from weifen invades the whole of lungs and form lung heat. So a remedy about lung heat is clearing away lung heat, this lung heat makes inevitably bleed in lungs, therefore a remedy in this case is clearing the lung to stop bleeding, or moistening the lung. Exterior heat sign means that exterior syndrome coexists with heat syndrome and it means that a remedy of this syndrome need to mix prescriptions for relieving exterior syndrome and heat-clearing prescriptions to treat this syndrome.

Metabolic Heat Production and Rectal Temperature of Newborn Calves

  • Mundia, C.M.;Yamamoto, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.3
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    • pp.304-307
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    • 1997
  • Rectal temperature (Tr), skin surface temperatures (Ts), and heart rate (HR) were measured continuously from birth (day 1) till day 7, while resting heat production (HP) was measured in a chamber on days 1, 3, 5 and 7, in order to study the characteristic variation of Tr in newborn calves by heat balance methods. Despite constant levels of milk being given to the newborn calves each day, daily mean resting HP was lowest on the day of birth, then increased to peak on day 3 and then decreased slightly thereafter. Daily mean HR was higher on days 2, 3 and 4, than on other days. Tr exhibited diurnal rhythms and daily mean Tr was low on day 1, high on day 3, and then decreased slightly after day 3. Daily average mean skin temperature (mTs) was similar on all days. Mean body temperature (Tb) exhibited diurnal rhythms and had a similar range between days, suggesting that heat balance and thermoregulation were carried out effectively on each day. The variation of Tb appeared to be synchronized with that of HP and suggested that newborn calves might use variations in the levels of Tb to facilitate the body's required levels of heart loss.

Biomechanics of Elliptical Trainer As an both Heat and Work - Related Experiment of a Fundamental Engineering Education : Energy Expenditure and Metabolic Cost (열과 일이 연관된 공학기초교육 실험으로써 Elliptical Trainers(ET) 생체역학 - 역학적 에너지 소비량 및 대사 소비량)

  • Hwang, Un-Hak
    • The Journal of Korean Institute for Practical Engineering Education
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    • v.2 no.1
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    • pp.146-153
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    • 2010
  • The physics theory applied to the elliptical health trainers can be a good example in engineering education. From the point of view of the physics education the measurement of mechanical and thermal energy expenditure in elliptical trainers can be related to the muscle activity, quantity of motion, and metabolic cost. We realized that the low speed training is effective for high basal metabolism due to increasing the muscle activity even if the high speed training is effective for training down. Elliptical Trainer may provide an effective oxygen exhaustion and thus effective training down. However, the metabolic cost does not have much relation to the amount of training under the high speed of trainer.

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CYTOTOXICITY OF DENTURE BASE RESINS (의치상 레진의 세포독성에 관한 연구)

  • Kim Seong-Kyun;Chang Ik-Tae;Heo Seong-Joo;Keak Jai-Young
    • The Journal of Korean Academy of Prosthodontics
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    • v.40 no.4
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    • pp.309-322
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    • 2002
  • The purpose of this study was to investigate the cytotoxicity and mutagenicity of denture base resins. According to manufacturer's instructions, resin specimens were made. Group 1 : heat-polymerizing acrylic resin (Luciton $199^{(R)}$) Group 2 : heat-polymerizing acrylic resin containing polyhedraloligosilsesquioxane(POSS resin) Group 3 : auto-polymerizing acrylic resin (Repair $Acrylic^{(R)}$) Group 4 : direct relining auto-polymerizing acrylic resin (Tokuso $Rebase^{(R)}$). Fresh specimens 24 hrs. and 72 hrs. soaked specimens in distil)ed water were made. Responses with metabolic assay and mutagenesis assay to eluates from resin specimens were measured. Cultures with medium alone provided controls. Cytotoxicity was assessed with agar overlay test. The results were as follows; 1. Group 4 showed higher cytotoxicity than Group 1, Group 2 and Group 3 in fresh, 24-an4 72-hour immersion caries (p<.05). Group 3 showed higher cytotoxicity than Group 2 in fresh cases and showed higher cytotoxicity than Group 1 and Group 2 in 24-and 72-hour immersion cases (p<.05) . Group 1 and Group 2 showed no significant difference. 2. All acrylic denture base resins skewed significant increase of cell activity as immersion time increased (p<.05). 3. Auto-polymerizing acrylic denture base resins skewed higher cytotoxicity than heat-polymerizing acrylic denture base resins (p<.05). 4. All acrylic denture base resins showed lower mutagenicity than controls (p<.05).

A Study on Thermal Satisfaction of Domestic Heat Wave Reduction Facilities (국내 폭염 저감 시설의 온열 만족도에 대한 연구)

  • Jun, Yong-Joon;Park, Lyool;Park, Kyung-Soon
    • Journal of the Korean Society for Geothermal and Hydrothermal Energy
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    • v.18 no.1
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    • pp.1-11
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    • 2022
  • As abnormal climates occur due to the increase in greenhouse gases at home and abroad, various problems such as human casualties, crop damage, energy depletion, and economic loss due to heat diseases, which are one of the extreme climate phenomena, are following one after another. In response, the government has established the 'Climate Crisis Response Special Committee' since 2018, when it recorded the greatest damage in history due to heat waves, and has been carrying out budget formation and reform of laws and systems every year to respond to heat waves. However, in relation to the heat wave damage reduction facility that is being expanded with a large budget, there is no prior research related to the degree of heat loss due to the use of the facility, the difference in effects between specific groups, and the economic effect that comes back compared to the invested budget. Therefore, from a midto long-term perspective, it is expected that it will be difficult to establish a clear direction for policy making. Therefore, in this study, representative facilities were selected according to the principle of heat reduction among the currently expanded heat damage reduction facilities, and a questionnaire survey was conducted for users of each reduction facility (waterfall, awning, pond, and elastic pavement). Accordingly, the change in the sense of heat according to the use of the heat damage reduction facility was checked, and the change in the sense of heat according to the group characteristics (gender, age, metabolic rate) was analyzed to examine the characteristics of the relationship between the facility and the users.

Comparison of Health Status and Mibyeong Characteristics between Cold Syndrome and Heat Syndrome by Cold Heat Syndrome Differentiation Score (한열변증 점수를 이용한 한증과 열증의 건강 상태와 미병 특징 비교)

  • Joo, Jong-Cheon;Lee, Siwoo;Park, Soo-Jung
    • The Journal of Korean Medicine
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    • v.39 no.1
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    • pp.13-21
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    • 2018
  • Objectives: The objective of this study is to develop the diagnostic tool to distinguish between cold syndrome (CS) and heat syndrome (HS). Methods: A total of 1,753 subjects were divided into three groups, those are CS group, intemediate group, and HS group, by the mean and standard deviation of the cold heat syndrome differentiation score using 7 point scale consisting of 9 items. Demographic characteristics, diseases history, health status, Mibyeong, syndrome differentiation were analyzed. Results: CS is characterized by women, elderly, and low body mass index. CS has a history of thyroid disease, cataract, depression, osteoporosis, and HS has a history of prostatomegaly. CS receives less social psychosocial stress than HS, and the quality of life associated with health status is lower than HS. CS group has the tendency to be tired, painful, sleepless, dyspeptic and anxious. Conclusions: CS is a set of symptoms associated with decreased energy metabolism and decreased metabolic function, and is more likely to be unhealthy than HS.