• Title/Summary/Keyword: meta-analysis method

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Evaluation of Cost-Effectiveness of Medical Nutrition Therapy : Meta-Analysis (메타분석을 이용한 임상영양서비스의 비용-효과성 평가)

  • 김현아;양일선;이해영;이영은;박은철;남정모
    • Journal of Nutrition and Health
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    • v.36 no.5
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    • pp.515-527
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    • 2003
  • Objectives: A meta-analysis of the literatures was conducted to evaluate the cost-effectiveness of medical nutrition therapy by dietitians. Methods : The 30 studies were identified from a computerized search of published research on MEDLINE, Science-Direct and the PQD database until May, 2002 and a review of reference lists. The main search terms were“dietitian”,“dietary intervention”,“nutrition intervention”, “cost”,“cost-effectiveness”and“cost-benefit analysis”. The subgroup analysis was performed by publication year, study design, intervention provider, type of patient (in/out-patient) and type of cost (total cost/direct cost). Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. Results : The 30 studies were identified using the electric database search and bibliographies. The 17 trials were eligible for inclusion criteria, then the systematic review and a meta-analysis were conducted on effectiveness and cost-effectiveness of medical nutrition therapy. The quality of the studies was evaluated using the quality assessment tool for observational studies. The quality score was 0.515 $\pm$ 0.121 (range : 0.279-0.711, median : 0.466). The meta-analysis of 17 studies based on the random effect model showed that medical nutrition therapy was highly effective in treating the diseases (effect size 0.3092 : 95% confidence interval 0.2282-0.3303). The vote-counting method, one of meta-analysis methods, was applied to evaluate the cost-effectiveness of medical nutrition therapy conducted by dietitians. Two criteria (method 1, method 2) for voting were used. The calculated p-values for method 1 (more conservative method) and method 2 (less conservative method) were 0.1250 and 0.0106, respectively. Medical nutrition therapy by dietitians was significantly cost-effective in the method 2. Conclusion. This meta-analysis showed that the effectiveness of medical nutrition therapy was statistically significant in treating disease (effect size 0.3092), and that the cost-effectiveness of medical nutrition therapy was statistically significant in the method 2 (less conservative method) of vote counting. (Korean J Nutrition 36(5): 515~527, 2003)

The Review on the Evidence-Based Study of Acupuncture - Systematic review and Meta-analysis - (침(鍼)의 근거중심적(根據中心的) 연구동향(硏究動向)에 관(關)한 고찰(考察) - Systematic review & Meta-analysis를 중심으로 -)

  • Back, Yong-Hyeon;Park, Dong-Seok;Kang, Sung-Keel
    • Journal of Acupuncture Research
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    • v.19 no.3
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    • pp.138-155
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    • 2002
  • Objective : The purpose of this study is to work on the problems and on the direction of the study regarding the evidence-based study of Acupuncture. Methods : We reviewed the PubMed electronic database. Eight articles of systematic review without meta-analysis and six articles without meta-analysis were selected. Results : In the study of eight articles of systematic review without meta-analysis, there were two articles on effectiveness of acupuncture and one on non-effectiveness of acupuncture. Four articles were about the changes according to the quality of randomized controlled trials. Also, one article was about the side-effect of acupuncture. In the study of six articles of systematic review with meta-analysis, there were two articles on Odds Ratio, two on Relative Risk, one on number-needed-to-treat, and two on 18 predefined methodological criteria. Conclusion : As the quality of RCTs was high, positive response decreased and as the quality of RCTs was low, positive response increased. For the study of evidence-based acupuncture, it is necessary that we conduct research on well-planned placebo acupuncture, large sample size, statistical method, method of searching and assessing literature and method of meta-analysis.

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Meta-analysis of the programming learning effectiveness depending on the teaching and learning method

  • Jeon, SeongKyun;Lee, YoungJun
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.11
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    • pp.125-133
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    • 2017
  • Recently, as the programming education has become essential in school, discussion of how to teach programming has been important. This study performed a meta-analysis of the effect size depending on the teaching and learning method for the programming education. 78 research data selected from 45 papers were analyzed from cognitive and affective aspects according to dependent variables. The analysis from the cognitive aspect showed that there was no statistically significant difference in the effect size depending on whether or not the teaching and learning method was specified in the research paper. Meta-analysis of the research data where the teaching and learning method was designated displayed significances in CPS, PBL and Storytelling. Unlike the cognitive aspect, the analysis from the affective aspect showed that the effect size of the research data without the specified teaching and learning method was larger than those with specified teaching and learning method with a statistical significance. Meta-analysis of the data according to the teaching and learning method displayed no statistical significance. Based upon these research results, this study suggested implications for the effective programming education.

A Meta-analysis of the Effects of Smoking Prevention Programs in Korea (흡연예방프로그램 효과에 대한 메타분석)

  • Park Eun-Ok
    • Journal of Korean Academy of Nursing
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    • v.34 no.6
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    • pp.1004-1013
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    • 2004
  • Purpose: The purpose of this paper was to describe the characteristics of smoking prevention programs in Korea, to estimate overall effect size of Korean smoking prevention programs, and to investigate effect size variations by program modality and instruction method. Method: Meta-analysis was performed on2l programs in 20 studies. Result: The estimation of overall effect size for knowledge and attitude was not possible because effect sizes were not homogeneous in this meta-analysis. However, effect sizes of studies that were socially influential programs or active/interactive methods were larger than information-oriented programs or passive/non-interactive methods in the pictures. The effects for behavioral outcomes were generally not as positive and not statistically significant. Q statistics showed that variations among effect sizes within program modality and instruction method classifications were heterogeneous. Conclusion: The results from this meta-analysis support the continued use of socially influential programs and active/interactive methods for smoking prevention programs. Because behavioral effect might be the fundamental objective of smoking prevention programs, the present results indicate that smoking prevention programs should consider adopting more effective programs.

Meta-analysis on the Effects of Exercise Therapy and Physiotherapy on Pain in Korean Patients with Chronic Low Back Pain (만성요통환자를 대상으로 운동치료 및 물리치료가 통증에 미치는 효과에 대한 메타분석)

  • Kim, Sung-Kyu;Lim, Bee-Oh
    • Korean Journal of Applied Biomechanics
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    • v.30 no.1
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    • pp.63-72
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    • 2020
  • Objective: The purpose of this study was to investigate meta-analysis on the effects of exercise therapy and physiotherapy on pain in korean patients with chronic low back pain. Method: Meta-analysis was performed on the type and method of treatment. A total of 23 experimental studies were coding into 31 individual studies, into types, methods, visual analogue scale (VAS), each pre/post value of the effect size was calculated by meta-analysis. Results: Sling exercise, stretching, thermal therapy, kinesio-taping, lumbar stabilization exercise, electrotherapy is large effect size (ES ≥ .08). In addition, big effects occurred in order of treatment period is more than 9 weeks, three times a week. Conclusion: Our results indicated that persistent treatment of chronic back pain is the most effective method of self-sufficiency rather than temporary relief.

Reliability Analysis for Structure Design of Automatic Ocean Salt Collector Using Sampling Method of Monte Carlo Simulation

  • Song, Chang Yong
    • Journal of Ocean Engineering and Technology
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    • v.34 no.5
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    • pp.316-324
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    • 2020
  • This paper presents comparative studies of reliability analysis and meta-modeling using the sampling method of Monte Carlo simulation for the structure design of an automatic ocean salt collector (AOSC). The thickness sizing variables of structure members are considered as random variables. Probabilistic performance functions are selected from strength performances evaluated via the finite element analysis of an AOSC. The sampling methods used in the comparative studies are simple random sampling and Sobol sequences with varied numbers of sampling. Approximation methods such as the Kriging model is applied to the meta-model generation. Reliability performances such as the probability failure and distribution are compared based on the variation of the sampling method of Monte Carlo simulation. The meta-modeling accuracy is evaluated for the Kriging model generated from the Monte Carlo simulation and Sobol sequence results. It is discovered that the Sobol sequence method is applicable to not only to the reliability analysis for the structural design of marine equipment such as the AOSC, but also to Kriging meta-modeling owing to its high numerical efficiency.

Optimization of a Train Suspension using Kriging Meta-model (크리깅 메타모델에 의한 철도차량 현수장치 최적설계)

  • Lee, Kwang-Ki;Lee, Tae-Hee;Park, Chan-Kyoung
    • Proceedings of the KSME Conference
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    • 2001.06c
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    • pp.339-344
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    • 2001
  • In recent engineering, the designer has become more and more dependent on the computer simulations such as FEM (Finite Element Method) and BEM (Boundary Element Method). In order to optimize such implicit models more efficiently and reliably, the meta-modeling technique has been developed for solving such a complex problems combined with the DACE (Design and Analysis of Computer Experiments). It is widely used for exploring the engineer's design space and for building meta-models in order to facilitate an effective solution of multi-objective and multi-disciplinary optimization problems. Optimization of a train suspension is performed according to the minimization of forty-six responses that represent ten ride comforts, twelve derailment quotients, twelve unloading ratios, and twelve stabilities by using the Kriging meta-model of a train suspension. After each Kriging meta-model is constructed, multi-objective optimal solutions are achieved by using a nonlinear programming method called SQP (Sequential Quadratic Programming).

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A step-by-step guide to Meta-analysis with dichotomous outcomes using RevMan in dental research (치의학 연구에서 RevMan을 이용한 이분형 결과변수를 분석하기 위한 메타분석의 단계적 안내)

  • Park, Su-Hyeon;Lim, Hoi-Jeong
    • The Journal of the Korean dental association
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    • v.56 no.1
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    • pp.18-40
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    • 2018
  • Meta-analysis is a statistical method that combines the results of individual studies on the same topic. This method is becoming popular, due to providing the combined result that individual studies cannot provide and giving a more precise result. Despite meta-analysis having such significance, there were few Korean guides for the use of the Review Manager (RevMan) software. This study will provide a step-by-step guide, using orthodontic mini-screw as a dental example, to help researcher carry out meta-analysis more easily and accurately.

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Effect of Aflatoxin on Feed Conversion Ratio in Broilers: A Meta-analysis

  • Suganthi, R. Umaya;Suresh, K.P.;Parvatham, R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.12
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    • pp.1757-1762
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    • 2011
  • Aflatoxins are natural contaminants of poultry feeds and feed ingredients and cause liver damage, immunosuppression, reduction in performance and mortality in broilers. A number of studies have been carried out to study the effects of aflatoxin on feed conversion ratio in broilers. The results on feed conversion ratio of 10 research articles in broilers fed with aflatoxin from first day of age to six weeks of age were compiled and were subjected to meta-analysis. Chi-square test and $Tau^2$ (heterogeneity co-efficient) were applied to test for significance of heterogeneity of studies. To integrate results, fixed effect model by Inverse Variance method (IV method) was used when heterogeneity was insignificant and otherwise random effect model by DerSimonian and Laird Method (DL method) was used. The results of meta-analysis showed that the adverse effect of aflatoxin on feed conversion ratio at the end of first week was negligible, second week was medium and third to six weeks was very large.

New Method for Combining P-values in Meta-Analysis (메타분석에서 새로운 P-Value 결합 방법)

  • Seon, Jeongyeon;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.26 no.5
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    • pp.797-806
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    • 2013
  • Meta-analysis is used in variety of areas to synthesize the results of previous studies. Among the methods for Meta-analysis, combining p-values is the simplest method; in addition Tippett (1931), Fisher (1932), Stuoffer at al. (1949), proposed various methods to combine p-values. We propose a new method to combine p-values based on exponential distribution. A Monte Carlo simulation study compares the power of the proposed methods with previous methods.