• Title/Summary/Keyword: metB

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The Clinical Studies for Muscle Energy Techniques on Patients with Nuchal Pain Caused by Traffic Accidents (교통사고로 유발된 경항통 환자의 근에너지기법(MET)의 효과에 대한 임상적 연구)

  • Jeon, Tae-Dong;Lee, Han-Gil;Hong, Seo-Yuong;Heo, Dong-Seok;Yoon, Il-Ji
    • Journal of Korean Medicine Rehabilitation
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    • v.19 no.1
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    • pp.125-134
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    • 2009
  • Objectives : The purpose of this study is to find out the effects of muscle energy techniques on nuchal pain caused by traffic accidents. Methods : The 20 patients were divided into 2 groups: group A was treated except muscle energy techniques and group B was treated with muscle energy techniques. Both groups were treated with acupunture treatment, physical theraphy and herbal medication. Patients were evaluated by McGill Pain Questionnaire-Short Form(SF-MPQ), Pain Disability Index(PDI) and Neck Disability Index(NDI) in traffic accident patients. Results : 1. Both Group were significantly decreased in sensory of SF-MPQ, VAS, PDI and NDI after 7 days of treatment. 2. Group B compared with the Group A was significantly decresed in VAS, PDI after 7 days of treatment. Conclusions : We found out that muscle energy techniques is considered to be effective and useful on nuchal pain caused by traffic accidents.

NOx Emission Characteristics of Diesel Passenger Cars Met Euro 6a, 6b and 6d Regulations on Off-cycles (Off-cycle에서 Euro 6a, 6b 및 6d 규제 만족 디젤 자동차의 NOx 배출 특성)

  • Kim, Jeonghwan;Kim, Sungwoo;Kim, Kiho
    • Journal of ILASS-Korea
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    • v.23 no.3
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    • pp.136-148
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    • 2018
  • Major countries have tighten their NOx regulation of diesel passenger cars. In the case of the EU, the regulation has been toughen up to 6.25 times since 2000. Despite the regulation the NOx concentration of the ambient has not been reduced proportionally. As these issues, to reduce NOx emission practically, Korea and the EU introduced the real-world driving emission (RDE) regulation and the test method that will be applied after 2017. In this paper, for the regulation to make a soft landing in Korea, 6 diesel passenger cars which met Euro 6a~6d regulation and were equipped with LNT/SCR were tested at a chassis dynamometer with environmental chamber applying the off-cycles (FTP, US06, SC03, HWFET and CADC) and several ambient conditions (-7 and $14^{\circ}C$) as well as certification modes (NEDC, WLTC@ $23^{\circ}C$). The result of the test showed that the ambient temp. and the engine load as a test mode impacted the NOx emission of the cars while the vehicles with SCR emitted NOx lower than with LNT. Additionally, to propose an effective RDE test method, the above result was compared with the results of the other papers which tested RDE using the same cars.

Evaluation of the Thermal Environment and Comfort in Apartment complex using Unsteady-state CFD simulation (Unsteady-state CFD 시뮬레이션을 이용한 여름철 공동주택 외부공간의 온열환경 및 쾌적성 평가)

  • Jeon, Mi-Young;Lee, Seung-Jae;Kim, Ji-Yoeng;Leigh, Seung-Bok;Kim, Taeyeon
    • KIEAE Journal
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    • v.10 no.4
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    • pp.67-73
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    • 2010
  • As more and more people desire to live in an apartment complex with a comfortable outdoor space, many construction company became interested in outdoor design. In order to increase the use of outdoor space and create the most pleasant environment, outdoor thermal environment and comfort should be evaluated quantitatively from the design stage. This study utilized ENVI-met 3.1 model to analyze outdoor thermal environment in apartment complex, and evaluated outdoor thermal comfort in 6 points of apartment complex. The physiologically equivalent temperature(PET) was employed as a outdoor thermal index. Playground B had a poor thermal environment with the maximum PET $43^{\circ}C$ (Very hot). Because shading by building and tree didn't affect outdoor thermal environment of playground B. To design comfortable outdoor space from the view point of thermal environment, the factors influencing Mean radiant temperature(MRT) and wind speed should be considered in design stage. Since it is difficult to control outdoor thermal environment compared with indoor environment, we should take into account an assessment for outdoor thermal environment and comfort in outdoor design stage.

Fiber Quality of Seven Mangrove Wood Species

  • ANDIANTO;Imam WAHYUDI;Rita Kartika SARI;Gustan PARI
    • Journal of the Korean Wood Science and Technology
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    • v.52 no.4
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    • pp.393-403
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    • 2024
  • As an archipelagic country, Indonesia is surrounded by large and small islands. Many mangrove plant species are found along the coasts surrounding large and small islands. Besides their conservation value, mangrove plants provide various benefits, including the use of their leaves, fruit, bark, and wood as raw materials in pharmaceutical and other industries. Additionally, mangrove wood is a potential raw material for pulp and paper production. It is essential to study the fiber dimensions of the wood to identify the appropriate characteristics of raw material for pulp and paper. Therefore, in this study, we comprehensively analyzed the differences in the wood fiber dimensions of seven mangrove species from the Indramayu Regency, West Java Province, namely Avicennia alba, Bruguiera gymnorhiza, Bruguiera cylindrica, Hibiscus tiliaceus, Sonneratia ovata, Sonneratia caseolaris, and Excoecaria agallocha. For this analysis, maceration followed the Forest Product Laboratory guidelines, and preparation followed the Sass method. The fiber length, diameter, and lumen diameter were measured using a light microscope. Based on the values of the length and dimension derivatives, the fibers of these mangrove wood species were grouped into quality classes II or III for use as raw materials for the pulp and paper industry. The wood fibers of H. tiliaceus, A. alba, S. caseolaris, and E. agallocha met the quality class criterion II, whereas wood species fibers of B. gymnorhiza, B. cylindrica, and S. ovata met the quality class criterion III.

Effects of Dietary Combinations of Vitamin A, E and Methionine on Growth Performance, Meat Quality and Immunity in Commercial Broilers

  • Lohakare, J.D.;Choi, J.Y.;Kim, J.K.;Yong, J.S.;Shim, Y.H.;Hahn, T.-W.;Chae, B.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.4
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    • pp.516-523
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    • 2005
  • The experiment was conducted to study the effect of dietary combinations of vitamin A (VA), vitamin E (VE) and methionine (Met) on growth performance, meat quality and immunity in commercial broilers. Ross chicks (n=3,630) were allocated to five experimental treatments with three replicates per diet. The dietary treatments were: VA 8,000 IU, VE 10 IU (diet 1); VA 12,000 IU, VE 10 IU (diet 2); VA 8,000 IU, VE 100 IU (diet 3); VA 12,000 IU, VE 100 IU (diet 4) and; VA 12,000 IU, VE 100 IU/kg diet and 20% Met higher than other groups (diet 5). The Met content in diet 1 to diet 4 were as per the requirement suggested by NRC. Separate vitamin premixes were prepared for each treatment diet as per the requirement of study. The 35 d study revealed significantly (p<0.0001) higher weight gains in broilers fed diet 3 and diet 5, than in the rest of the groups during starter phase (0-3 weeks) only. The feed intake did not vary significantly at all phases of study, but feed efficiency was significantly (p<0.05) lower in diet 1 during starter and overall phase (4-5 weeks). The bone strength and bone composition, except bone calcium, remained unaffected due to experimental diets studied after 35 d of experimental feeding. The thio-barbituric acid reactive substances (TBARS) were significantly (p=0.0013) lower in the breast meat in group 5, followed by group 3, than in the rest of the groups. The immune studies conducted, antibody titers to sheep red blood cells, thickness index to phytohaemagglutinin-P, and heterophil: lymphocyte ratio, did not show any significant difference among treatments. It could be concluded that supplementation of VA, VE and Met at higher levels could be beneficial to broilers only during the starter phase.

A Pilot Study for the Construction of Sasang - Constitutionally Differentiated Model of the Metabolic Syndrome with Focus on 40 $\sim$ 49 year old Taeumin (대사증후군의 체질병증 모델 구축을 위한 예비연구 - 40대 태음인을 중심으로 -)

  • Kim, Yun-Hee;Lee, Jun-Hee;Lee, Eui-Ju;Koh, Byung-Hee
    • Journal of Sasang Constitutional Medicine
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    • v.21 no.2
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    • pp.123-136
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    • 2009
  • 1. Objectives : This study is a pilot study to construct of metabolic syndrome model with constitutional type. We focused on the correlation of Metabolic syndrome(MetS) and ordinary symptoms with Taeumin at 40. 2. Methods : 32 subjects who had taken health examinations and diagnosis of Sasang constitution from Oct 1, 2008 to Dec 31, 2008 at Kyung-Hee medical center were included and underwent B-mode ultrasonography for measurement of intima-media thickness of common carotid arteries. MetS was defined by the criteria of the criteria of the National Cholesterol Education Program Adult Treatment Panel III. 3. Results and Conclusions : Mean intima-media thickness of common carotid artery was higher in subjects with MetS compared with control subjects(0.56$\pm$0.12 vs 0.54$\pm$0.08mm) however. The ordinary symptoms shown to differentiate the MetS group and the control group were related to "dark urine color," "dryness of eyes," and "night sweat". Therefore, these ordinary symptoms can be said to be indicators of the Taeumin with Mets syndrome.

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Biodegradation of Crude oil by Marine Bacterium Pseudomonas sp. CHCS-2 and Composition of the Biosurfactant (해양세균 Pseudomonas sp. CHCS-2에 의한 원유분해 및 생물유화제의 성분 분석)

  • 김학주;김봉조;하순득;황선희;공재열
    • KSBB Journal
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    • v.14 no.2
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    • pp.192-197
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    • 1999
  • marine bacterium Pseudomonas sp. CHCS-2 produced the biosurfactant in the culture broth which contained 2%(w/v) arabian light crude oil and the productivity of biosurfactant was increased with the addition of glucose. The crude oil in the culture broth was degraded by this strain and carbon chain of $_nC_{12}~_nC_{22}$ was completely degradaded during the incubation for 196 h. The crude biosurfactant was purified by Amberlite XAD-7, Sepharose CL-4B and DEAE-Sepharose CL-6B column chromatography. Therefore, 0.21g/L of the purified biosurfactnat was obtained. The purified biosurfactant was a type of lipoprotein and the molecular weight was estimated as 67kDa by SDS-PAGE. The lipid composition was identified as octadecanoic acid by gas chromatography/mass spectrometry. And then, the N-terminal amino acid sequence of the protein was determined as Ser-Val-lle-Asn-Thr-lle-X-Met-lle-Gly-Gln-Gln- and the sequence did not show homology to any other known lipoprotein. Therefore, the purified lopoprotein was predicted novel biosurfactant.

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3-Deoxysappanchalcone Inhibits Cell Growth of Gefitinib-Resistant Lung Cancer Cells by Simultaneous Targeting of EGFR and MET Kinases

  • Jin-Young Lee;Seung-On Lee;Ah-Won Kwak;Seon-Bin Chae;Seung-Sik Cho;Goo Yoon;Ki-Taek Kim;Yung Hyun Choi;Mee-Hyun Lee;Sang Hoon Joo;Jin Woo Park;Jung-Hyun Shim
    • Biomolecules & Therapeutics
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    • v.31 no.4
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    • pp.446-455
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    • 2023
  • The mechanistic functions of 3-deoxysappanchalcone (3-DSC), a chalcone compound known to have many pharmacological effects on lung cancer, have not yet been elucidated. In this study, we identified the comprehensive anti-cancer mechanism of 3-DSC, which targets EGFR and MET kinase in drug-resistant lung cancer cells. 3-DSC directly targets both EGFR and MET, thereby inhibiting the growth of drug-resistant lung cancer cells. Mechanistically, 3-DSC induced cell cycle arrest by modulating cell cycle regulatory proteins, including cyclin B1, cdc2, and p27. In addition, concomitant EGFR downstream signaling proteins such as MET, AKT, and ERK were affected by 3-DSC and contributed to the inhibition of cancer cell growth. Furthermore, our results show that 3-DSC increased redox homeostasis disruption, ER stress, mitochondrial depolarization, and caspase activation in gefitinib-resistant lung cancer cells, thereby abrogating cancer cell growth. 3-DSC induced apoptotic cell death which is regulated by Mcl-1, Bax, Apaf-1, and PARP in gefitinib-resistant lung cancer cells. 3-DSC also initiated the activation of caspases, and the pan-caspase inhibitor, Z-VAD-FMK, abrogated 3-DSC induced-apoptosis in lung cancer cells. These data imply that 3-DSC mainly increased mitochondria-associated intrinsic apoptosis in lung cancer cells to reduce lung cancer cell growth. Overall, 3-DSC inhibited the growth of drug-resistant lung cancer cells by simultaneously targeting EGFR and MET, which exerted anti-cancer effects through cell cycle arrest, mitochondrial homeostasis collapse, and increased ROS generation, eventually triggering anti-cancer mechanisms. 3-DSC could potentially be used as an effective anti-cancer strategy to overcome EGFR and MET target drug-resistant lung cancer.

Properties of Sunglass Lenses by Non-Destructive Test for the Sunglass Standards (비파괴식 검사를 통한 선글라스의 품질에 관한 연구)

  • Lim, Yong-Moo;Shim, Moon-Sik;Sim, Hyun-Seog;Kim, Sang-Moon
    • Journal of Korean Ophthalmic Optics Society
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    • v.6 no.1
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    • pp.125-131
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    • 2001
  • In this study, we compared the properties of 23 high and 55 low price sunglass lenses with the standards in the ordinary optical properties, materials, coloration, UV, IR and luminous transmittance, color acceptance for traffic signal, chromaticity and contrast sensitivity. The ordinary optical properties of the lenses met comparatively the requirements of the KS standard. The HIGH-type and LOW-type lenses were primarily made by glass and acrylate, respectively. In the coloration, HIGH-type was in group around neutral color but LOW-type was distributed widely on the line between 570 nm and 485 nm. There are fails in 7% of HIGH-type and 18% of LOW-type in the stimulus purity of the luminous transmittance. Wavelength of the UV/VIS cut-off was over 350 nm for HIGH-type but 6% of LOW-type was under 350 nm. In the erythemal UV, all HIGH-type met the needs of standards but 5 LOW-type failed with DIN standard In the near UV, KS standard worked in stringency, and HIGH-type showed more failure than LOW-type. The characteristics of the IR transmittance of HIGH-type was better than that of LOW-type. In the color acceptance of traffic signal, all HIGH-type met the needs of ANSI standards but 21.8% of LOW-type failed with the standard. In the contrast sensitivity tested with various coloured sunglasses, the value increased with increasing of Land decreasing of test distance. In view of the results so far, HIGH-type met with excellent properties as compared with LOW-type.

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NOx Emission Characteristics of Diesel Passenger Cars Met Euro 6a and 6b Regulations on Off-cycles (Off-cycle에서 Euro 6a 및 6b 규제 만족 디젤 자동차의 NOx 배출 특성)

  • Kim, Sung-Woo;Lim, Jae-Hyuk;Kim, Ki-Ho
    • Journal of Power System Engineering
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    • v.21 no.6
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    • pp.68-78
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    • 2017
  • Major countries have tighten their NOx regulation of diesel passenger cars. In the case of the EU, the regulation has been toughen up to 6.25 times since 2000. Despite the regulation the NOx concentration of the ambient has not been reduced proportionally. Futhermore, some manufacturers were disclosed using a defeat device for meeting the regulation illegally. As these issues, to reduce NOx emission practically, Korea and the EU introduced the real-world driving emission(RDE) regulation and the test method that will be applied after 2017. Also, the US has used the test equipment(PEMS) to detect a defeat device. In this paper, for the regulation to make a soft landing in Korea, 4 diesel passenger cars which met Euro 6a~6b regulation and were equipped with LNT/SCR were tested at a chassis dynamometer with environmental chamber applying the off-cycles(FTP, US06, SC03, HWFET and CADC) and several ambient condition(-7 and $14^{\circ}C$) as well as certification mode(NEDC, WLTC@ $23^{\circ}C$). The result of the test showed that the ambient temp. and the engine load as a test mode impacted the NOx emission of the cars while the vehicles with SCR emitted NOx lower than with LNT. Additionally, to propose an effective RDE test method, the above result was compared with the results of the other papers which tested RDE using the same cars.