• 제목/요약/키워드: mental effect

검색결과 1,469건 처리시간 0.028초

노년기 영성과 불안.우울 및 삶의 질과의 관계 (The Relationship of Spiritual Well-being and Anxiety, Depression and Quality of Life in Active Old Age)

  • 염형욱;정성덕;서완석;구본훈;배대석
    • Journal of Yeungnam Medical Science
    • /
    • 제22권1호
    • /
    • pp.27-42
    • /
    • 2005
  • 본 연구는 노인의 영적인 안녕 정도를 측정하여 그들의 영적 안녕정도가 불안, 우울 및 삶의 질에 어떠한 영향을 미치고 있는 것인지를 검토하고, 불안 및 우울과 같은 노인의 정신 건강 상태를 평가할 때 영적 안녕이 중요한 요인으로 인정되는지 여부를 평가하기 위하여 활동성 노인 184명을 대상으로 실시하였다. 영적 안녕 정도는 영적 안녕 척도를 사용하였는데 두 개의 하위 척도인 종교적 안녕과 실존적 안녕으로 평가를 하였으며, 불안과 우울은 불안 우울 통합척도를 사용하여 측정하였다. 삶의 질에 대한 평가는 삶의 질에 대한 척도를 이용하여 주관적인 삶에 대한 느낌(QOL1)과 전반적인 삶에 대한 만족도(QOL2)로 나누어 평가하였다. 먼저, 영적 안녕 정도에 유의하게 영향을 미친 정신사회적인 요인들에는 교육을 받은 경우(p<.001), 종교가 있을 때(p<.001), 종교에 대한 만족도가 높을 경우(p<.001), 신체적으로 건강할수록(p<.01), 신체적 병력이 없는 경우(p<.05), 생활에 대한 만족도가 높을 경우(p<.001) 영적안녕척도 점수가 유의하게 높은 것으로 나타났으며, 특히 실존적 안녕척도 점수에서 유의한 차이를 나타내었다. 다음으로, 영적 안녕 정도와 삶의 질을 향상시켜주면서 불안과 우울을 감소시켜준 공통적인 정신사회적 요인으로는 종교의 만족 정도, 신체적 건강 상태 및 생활의 만족 정도 등으로 평가되었다. 마지막으로, 영적안녕척도점수와 불안, 우울 및 삶의 질 간의 관계를 살펴보고자 상관관계 분석을 한 결과, 영적안녕정도와 불안, 우울 및 삶의 질이 유의한 상관관계가 있는 것으로 나타났으며, 중다 회귀분석을 통해 평가한 결과, 영적 안녕 정도 중 특히 실존적 안녕 정도가 높을수록 불안 우울 통합 척도의 불안(p<.001)과 우울(p<.001) 모두가 낮아졌으며, 삶의 질 척도 중 삶에 대한 주관적인 느낌에 대한 척도 점수(QOL1)는 유의하게 감소(p<.001)하였고, 삶에 대한 전반적인 만족도(QOL2)는 유의하게 증가(p<.001)하였다. 따라서 종교적 안녕 정도보다 실존적 안녕 정도가 더 밀접한 영향을 미쳤다. 이상과 같이 활동성 노인에게 있어 영적 안녕 정도와 불안, 우울 및 삶의 질이 유의한 상관관계가 있었으며 노인 정신건강에 대한 평가를 실시할 경우 영적안녕이 중요한 요인이 됨을 검증해 볼 수 있었다.

  • PDF

도교의학(道敎醫學)에 관한 연구(硏究) (한의학(韓醫學)과 연관(聯關)된 부분(部分)을 중심(中心)으로) (The study of the relation between the medicine of Taoism and oriental medicine)

  • 이병서;윤창열
    • 대한한의학원전학회지
    • /
    • 제6권
    • /
    • pp.252-305
    • /
    • 1993
  • I have studied the relation between a Taoist(道家) and the oriental medicine(韓醫學), it is summerized as following. 1. According to the relation between a Taoist(道家) and the oriental medicine, Lao-tzu(老子)' mathematical principle that had an influence on Three yin-three yang(三陰三陽) theory of the oriental medicine, idea of natural philosopy(自然無爲) and the freedom from avarace(無慾) on the oriental medicine. 2. Vital essence and energy theory(精氣設) in a Taoist not only can be seen in Lao-tzu' Do dug gyung(老子道德經), Maengza(孟子), Guanza(管子), but also its principle has something to do with Nei Ching's Vital essence and energy theory(精氣設). 3. Danjungpa(丹鼎派) can be divided into Naedansul(內丹術) which preserves through the breath and Oedansul(外丹術) which makes one a Taoist hermit. If he takes magic portions(金丹), they had a great effect on Yangsanghak(養生學) and was actually concerned with oriental doctors who was known to us. 4. If medicine of Taoism is classified, it can be divided into three categories. Boiled solution(渴液), Pharmacopea "Ben cao"(本草), Acupuncture & moxibustion(針灸), Magic portions(外丹) are used in the first category. Chinese setting-up and Therapeutic exercises(導引), Josik(調息), Naedan(內丹), Byugok(辟榖), Naeshi(內視), Banjung(房中) belong to second category. The religious contents such as Bu(符), Jeum(占), Cheum(籤), Ju(呪), Je(齊), Gido(祈禱), taboo are implied in third category. 5. In the history of the medicine of Taoism and oriental medicine, they are called animism, shamanism, Mu(巫) or Ye(毉), not separated at first period. In the end of junguk(戰國時代), Ye(醫) was clearly distinguished from Mu(巫) and then Mu(巫) was developed into medicine of Taoism and ye(毉) into the present form of oriental medicine. 6. The oriental medicine doctors that are concerned with Taoism are Bakgo(伯高), Geyugu(鬼臾區), Soyu(少兪), Noigong(雷公), Pyujak(篇鵲), Sunuyi(淳于意), Hwata(華陀), Hwangbomil(皇甫謐), Hangang(韓康), Dongbong(童奉), Heuson(許遜), Galhong(葛洪), Dohongyung(陶弘景), Damlan(曇鸞), uyjajang(葦慈藏), Sonsanak(孫思邈), Wanguing(王氷), Jegonghwalbul(濟公活佛), Yuwanso(劉完素), Judonge(朱丹溪), Leesijin(李時珍), Johakmin(趙學敏), Ougu1(吳杰) etc. 7. The view of a human body in the medicine of Taoism affected the oriental medicine on the ground that man was regarded as a microcosm(小宇宙), so he was compared to a nation or heaven and earth. 8. The anatomy of medicine of Taoism gave a detail description of five visceras and each organs, the heart, center of mental function, Mirie(尾閭) which has an relationship to the training of Naedan(內丹修練). In this resrect, as it is accord with the acupunture point of oriental medicine, therefore we can find that Taoism influenced oriental medicine, also explicit study was achieved. 9. Acient people believed that the goo in the human lxxIy, one of the characteristics of the medicine of Taoism cured the patients and then protected him from the disease. If a man was taken ill, they had him cured by making the god's name which corresponded to its disease, calling him communicating with him, and asking him to deprive him of illness. This treatment was used to live and be kept young eternally. In this respects, we can see that they emphasized on the attitude of Bulchiyibeung chimibeung(不治己病治末病) and psychological treatment. 10. Samsi thoery(三尸說) that one's fortune, disaster, health, and disease in the world are at the mercy of his good or bad conduct, is concerned with Taoism and treatment with the oriental medicine. 11. Guchung(九蟲) is more closly associated with the religious aspect rather than with the medical aspect. Because of the similarity of the mcdern parasitism, its study has an important meaning. 12. The respect for the human life is reflected in jeunsi(傳屍), with Samsi-guchung theory(三尸九蟲說), which is considered as mxIern tuberculosis.

  • PDF

중학교 남학생들의 건강관리 실천과 이에 영향을 미치는 요인 조사 연구 (A Study OR Investigation of the Factors having Affect on Junior Highschool Boys관 Practice of Health Care)

  • 기경숙
    • 대한간호학회지
    • /
    • 제15권1호
    • /
    • pp.59-75
    • /
    • 1985
  • Accepting the health as the fundamental human right, the nation and society came to admit the duty to give it to all the people. Korean government is expanding the Primary Health Care as one of the policies for developing the people's health by the lead of community. Like this current situation the School Health Service which is the center of community Health Service schould be active to keep, promote and maintain the health of students and teachers. This investigation was attempted to help to establish the basis of the Health Education Program which would perform the health education efficiently and bring the reforming of student's health control, by measuring the degree of junior high school student's practice concerning health care and con-firming the relationship of knowledge, concern and level of health. The subjects for this study were made up 296 boys at the third grade in a school, located in Seoul. The tool for this study was questionaire. Data were collected for five days, September 22∼26, 1983. The investigators explained the students how to answer the questions of the survey questionaire and then collected the survey cards immediately. The data were analyzed by means of percentages, Pearson Correlation Coefficient and Stepwise Multiple Regression. The results of this study are as follows. 1. The subjects' reaction to the practice concerning Health Care; According to the average proportion of practice concerning health care, subjects' practice in the aspect of Infectious Disease Care is the highest 82.4% and they showed their practice in the aspect of the accident prevention by 77.5% and in the aspect of mental health by 74.8%. Their practice in the aspect of personal hygiene and daily lifehabit is the lowest 71.2%. 2. Health Knowledge; The whole mark distribution of health knowledge is ranged from the lowest 4 point to the highest, 30 point, therefore point range is 26.0. The Average point is 16.58. 11.2% of students solved more than two thirds of personal knowledge levels. 81.4% of students did more than one third of them. 7.415 of students did less than one third of them. 3. Health Concern; The Students of the average 3.99 point respond positively to the question about the health concern, ‘They think health is more important than money’, this is the highest rate. The students of the average 2.78 respond“when they are sick, they enter the appointed hospital where they own choose”, while it is the lowest. 4. Subjects' response to the health level are at follow: Very healthy 26.0%, healthy 47.0%, less healthy 10.5%, 34.9% of them have ever been sick within two weeks, the number of symptoms they reported amount to 114 and the number of cases poi one person is 0.35. 5. The hypotheses test about the practice concerning health care and the factor which effect on it. 1) The main first hypothesis:“The more knowledge of health the subjects have, the better they practice health care.”was accepted. (r=0.1582, p <0.05) 2) The minor first hypothesis:“The more interest in health subjects have, the better they practice”was accepted. (r=0.4354, p <0.001) 3) The minor second hypothesis;“The healthier subjects are, the better they practice health care”was accepted. (r=0.1069, p<0.05) As other test, partical correlation test is performed in other refine whether health knowledge, a fact influencing the students practice concerning health care, is associated with the practice after controlling the third variables. First, after controlling health concern, the correlation of health knowledge and practice concerning health care was kept. (r=0.1347, p <0.005) Second, after controlling health level, the correlation of health knowledge and practice concerning health care was kept. (r=0.1526, p <0.005) And finally, after controlling economic state, the correlation of health knowledge and practice concern-ing health care was kept. (r=0.1413, p <0.05) Additionally Stepwise Multiple Regression between practice concerning health care and variables. 1.6591 of compliance was explained with the know-ledge (F=5.584, p <0.05), 20.0% of compliance was explained with the health concern added to knowledge. (F=63,213, p <0.005) As the above, health knowledge obviously have effects on the practice about the health care. But, contrary to researcher's expectation, health concern has more affects than health knowledge. Therefore, we must grope the plan to enhance health concern through the regular curriculum and systematic health education for students. Besides, we must study further on, to find the factors which have affect on the practice concerning health care.

  • PDF

소아 청소년 정신과 입원 환자에서 Risperidone의 효과 및 안정성에 관한 연구 (THE EFFICACY AND SAFETY OF RISPERIDONE IN CHILD & ADOLESCENT PSYCHIATRIC INPATIENT)

  • 박정현;김붕년
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • 제16권2호
    • /
    • pp.239-250
    • /
    • 2005
  • 목적 : 소아 청소년 정신과 환자에서 비전형 항정신병약물인 risperidone에 대한 효과 및 안전성에 대한 자료를 얻고자 하였다. 방법 : 2001년 1월에서 2002년 6월까지 서울대병원 소아 청소년 정신과 병동에 입원한 환자 중 risperidone이 사용되었던 5.4세에서 17.3세 사이의 환자 31명(남 18, 여 : 13)을 대상으로 후향적인 진료기록지 검토를 시행하였다. 결과 : Risperidone이 사용된 주된 정신과 진단은 정신분열병 및 기타 정신증, 정신병적 증상이 동반된 I형 양극성 장애, 뚜렛장애, 자폐스펙트럼 질환, 혼합형 표현성 및 수용성 언어장애, 주의력결핍 과잉행동장애 및 품행장애, 강박장애 등이었으며 이 중 12명에서 정신지체가 동반되었다. Risperidone사용의 주된 목표 증상은 정신병적 증상(n=13, $41.9\%$), 공격성, 충동성, 과잉행동, 상동증 등과 같은 행동 증상(n=10, $32.3\%$), 만성적이고 심한 틱 증상 (n=8, $25.8\%$)이었다. Risperidone의 효과는 risperidone의 목표 증상에 대한 CGI(Clinical Global Improvement)로 평가되었는데 $67.7\%$에서 중등도 이상의 호전을 보였고 평균 7.5개월 동안 치료효과가 유지되었다. Risperidone의 평균 하루 사용량은 $0.05{\pm}0.1mg/kg$이었으며, 정신병적증상군이 0.07mg/kg로 다른 두 증상군(0.04mg/kg)에 비해 의미 있게 높았다. 부작용으로는 체중증가(n=23)가 가장 흔하였으며 그 외 추체외로계 증상(n=15), 자율신경계증상(n=6), 진정작용(n=5), 고프로락틴혈증(n=2) 등 다양한 부작용이 보고되었다. 그러나 부작용으로 인해 약물을 변경한 경우는 없었으며 외래 마지막 방문 시 $90\%$에서 risperidone을 유지하고 있어 약물내약성은 비교적 우수한 것으로 평가되었다. 결론 : 비전형 항정신병 약물인 risperidone은 정신병적 증상, 공격성, 충동성, 과잉행동, 상동행동을 포함하는 행동증상, 만성적이고 심각한 틱증상 등 다양한 소아 청소년 정신병리의 치료에 비교적 안전하고 효과적인 약물이 될 수 있을 것으로 평가된다. 향후 risepridone의 효과 및 안전성에 대한 보다 장기적이고 체계적인 연구가 필요할 것이다.

  • PDF

난임여성의 정서적 특성에 따른 산림치유 프로그램 요구 분석 (Analysis of Forest Therapy Program Needs according to Emotional Characteristics of Subfertile Women)

  • 부서윤;신창섭
    • 한국환경생태학회지
    • /
    • 제34권1호
    • /
    • pp.72-84
    • /
    • 2020
  • 본 연구의 목적은 난임 여성을 위한 산림치유 프로그램 개발의 기초자료를 제공하는 데 있다. 본 연구는 탐색적 연구로 난임 여성의 정서적 특성과 정서적 특성에 따른 산림치유 요구도가 무엇인지 밝혀내어 산림치유 프로그램 개발과 운영을 위한 기초 자료를 제공할 것이다. 본 연구는 서울 소재 난임 전문병원에 내왕하는 난임 여성 200명을 대상으로 난임 여성의 정서적 특성과 산림치유 프로그램 요구도에 대한 33항목을 설문한 조사연구이다. 자료 분석은 SPSS 21.0 프로그램을 이용하여 난임여성의 정서적 특성과 산림치유 프로그램에 대한 요구 사이의 상관관계와 중요도를 파악하고자 빈도분석과 교차분석, 일원분산분석을 진행하였다. 난임 여성들의 정서적 특성은 임신에 대한 압박감, 불안 및 두려움, 우울, 절망감, 무기력, 외로움, 슬픔, 수치심 및 죄책감, 조급함과 답답함, 분노 및 과민함 등으로 나타났다. 난임 여성의 임신에 대한 압박감, 우울, 절망감, 무기력, 외로움, 슬픔과 분노와 과민함, 불안 및 두려움이 높게 나타났다. 난임 여성의 정서적 특성에 따른 산림치유 프로그램 요구도 차이를 알 수 있었다. 임신에 대한 압박감과 수치심 및 죄책감에 따라서 난임 부부 산림치유 프로그램의 운영 형태가 유의한 차이가 있는 것으로 나타났다. 불안과 두려움에 따라서 프로그램 참여 경험이 유의한 차이가 나타났고, 우울, 절망감, 무기력, 외로움, 슬픔에 따라서는 산림치유 프로그램에 참여하지 못하는 이유에 유의한 차이가 있는 것으로 나타났다. 조급함과 답답함에 따라서는 희망하는 산림치유 프로그램 동반 참여자에 대해 유의한 차이가 있는 것으로 나타났다. 분노와 과민함에 따라서 산림치유 프로그램 참여경험 및 난임 여성을 위한 산림치유 프로그램을 통한 자조모임의 효과에 대해 유의한 차이가 있는 것으로 나타났다. 본 연구의 분석 결과가 난임 여성의 심신건강 증진을 위한 산림치유 프로그램을 개발하는 데 기초자료로 활용되기를 기대한다.

뇌졸중 환자의 주간 재활간호센터에 대한 요구 (The Needs for Rehabilitation Day Care Center in Stroke Patients)

  • 고선화;이명하
    • 가정∙방문간호학회지
    • /
    • 제9권2호
    • /
    • pp.114-128
    • /
    • 2002
  • In order to provide information for the establishment and maintenance of a rehabilitation day care center for stroke patients. this study is to assess needs for the rehabilitation day care center of the stroke patients and to identify the factors influencing the needs for the center. The data were collected face-to-face interview with 223 stroke patients. using a structured questionnaire. from September 24. 2001 to November 20. 2001. Major findings are as follows. 1. Most of the participants($94.6\%$) needed rehabilitation day care center for stroke patients. $95.5\%$ of participants were willing to use the rehabilitation day care center. 2. Also the score of the needs for the center's health services was $2.84\pm60$ out of 4.00. In regards to the sub-contents. while the physical exercise therapy showed the highest mark($3.54\pm71$) in the needs. the following marks showed physical therapy($3.48\pm79$), training for the memory. thinking and judgment($3.30\pm93$). training for ADL($3.09\pm99$). health education program($3.04\pm93$). In the meantime. the expected effects from the use of the center are $2.89\pm61$ out of 4 and its sub-contents showed that the center would promote their physical and mental well-being($3.30\pm74$) and the center would be more effective than in home care($3.12\pm70$). 3. Meanwhile. the desired frequency of use in the future and distance had significant interrelation with their families living together(p<.05). In addition those who paid to use it differentiated significantly according to their ages and the types of insurance they had(p<.05). 4. The needs in degrees of speech disorder therapy and hobbies & amusements. the patients with other disease had significantly higher degrees than those patients without it (p<.05). Also in regard to the need degrees for physical therapy. healthy education programs and individual counseling including their families. the degrees of the patients with speech disorders were significantly lower than those of the patients without the disorder (p<.05). On the other hand. the patients with speech disorders were significantly higher than those patients without it in the need degree of the speech disorder therapy (p=.000). And the needs in degree concerning about speech disorder therapy. physical exercise therapy. training for ADL. medicinal substances therapy and family education were negatively correlated with the ADL (r=-.236$\sim$.305, (p<.005). 5. Finally. the expected effect of using the rehabilitation day care center showed significant differences statistically according to whether or not they had other disease (p<.05). In conclusion. the study showed the stroke patients were willing to use the center and had a high requirements for it and they especially had relatively high need degrees for the physical exercise therapy. physical therapy. training for memory. thinking and judgment. and healthy education program. And significant factors for the use of the center were their ages. types of insurance. family cohabitation. complications and speech disorders. ADL and so forth. Accordingly. the rehabilitation day care center needs to be established for the stroke patients and the center should develop rehabilitation care programs. which are individual and special programs customized for each patient's characteristics and health conditions.

  • PDF

농촌주민의 흡연 및 음주 실태와 이에 영향을 미치는 요인분석 (An Analysis of Determinants of Smoking and Drinking of Community people in Rural area)

  • 남철현
    • 보건교육건강증진학회지
    • /
    • 제6권1호
    • /
    • pp.48-59
    • /
    • 1989
  • The study was designed. to analyse the factors effecting to smoking and drinking of community people in rural area. The study has been surveyed through interviews by trained college students for 1,846 residents who live in rural area(Eup or Myun office is located)for 20days(from 3rd. to 22M. in August, 1988) The summary and conclusions are as follows. 1. The number of answers on the questionaires was 1846. And the percent of man was 55.7 %(woman 44.3 %). Among age group 20-29 years group with 30.4 % was larger than any other group. Anaverage age of answers was 38.6 years. 2.In the period of residence, 21.5 % of the residents lived within 5 years(This group was larger than any other group). In occupations, workers in agriculture and fishing was more than other job occupants. In education, the percent of high school graduates was 44.0 %(higher than any other group) 3.The smoking rate of rural residents was 41.8 %and man's smoking rate was 76.0 % (woman's smoking rate was 7.6 %). These rates were higher than the rates in 1985 (The smoking rate of nation was 32.0 %). First of all, woman's smoking rate increased rapidly 4.As for smoking amount, in male 52.8% of smokers smoked a cigarette case (20 cigarettes) in a day, and 16.9 % of smokers smoked more than one cigarette case. In female 42.5 % of woman smokers smoked a half case in a day and the rate of non-smokers diminished to 77.8 % 5.The rate of non-smokers in 21-29 years group was higher than any other group and a smoking rate increased as an age increased. However, a smoking amount decreased as an age increased. This suggests that people are more concerning about their health as their ages increase.. 6.The smoking rate of college graduates was 58.8 %(higher than any other group) and in a smoking amount 36.4 % of college graduates, 29.8 % of high school graduates smoked more than a cigarette case in a day. This shows that people in a higher education group smoke more than those in other groups. 7.As for non-smoking rate, students, service job workers, company employees, and teachers was 54.1%, 43.4%. 40.1% and 39.5%. respectively. As for smoking rate, workers in agriculture and fishing was the highest level of all job employees. Public officers smoked less than the workers in agriculture and the smoking rate of teachers was less than that of public officers. with regard to smoking amount. above one cigarette case in a day was 39.9 % in public officers, 39.2 % workers in agriculture and fishing, 37.9 % in businessmen, 34.2 % in teachers, 31.9 % in service job employees and 31.6 % in a company employees. 8.The variables which had an effect on smoking were sex (B=.1701), job(B=.1688), education(B=.1671), age(B=.1125). These variables were significant in P<0.05 statistically. Explanatory variance level was 19% 9.The drinking rate of community residents was 61.8% and man's drinking rate was 81.7%(woman's drinking rate was 38.9%). As drinking rate 18.0%(the highest rate) of man drinkers drank 3 bottles of beer in a general drinking and 12.1% of them drank more than 10 bottles. 12.1% (the highest rate)of woman drinkers drank 2 cups of beer. The rising rate of woman's drinking of alcohol was remarkable. 10.Each non-drinking rate of age groups was 27.6% (in 20-30 years group), 28.0% (in 30-39 years group), 28.9%(in 40-49 years group) and 32,6%(in 50-59 years group), 10,7%(the highest rate) of 20-29 and 30-39 years groups drank above 3 bottles. 7.5% of 20-29 years group and 7.7% of 30-39 years group drank above 10 bottles. In 40-49 years group, 14.4 % of them drank a bottle and 8.1% of them drank above 10 bottles. In 50-59years group, 14,2% of them drank 2 bottles and 5.3 % of them drank above 10 bottles. This shows that a drinking rate decresed as an age increased. 11.Non-drinking rate was higher as an education level was lower. Each non-drinking rate of non-educated group, elementary school group, middle school group and high school group was 41.0 % of high school graduates and 14.5 % of college graduates drank 3 bottles of beer. 9.7 %(the highest rate) of college graduates drank above 10 bottles, in general drinking. 12.Each non-drinking rate of businessmen, farmers, service job workers, and students was 31.3%, 28.2%, 26.8% and 25.9%. However, Each drinking rate of public officers, company employees and teachers was 73.3 %, 72.2 % and 68.4 %. This tells us that the drinking rate of mental workers is higher than that of physical workers. 14.9 % of farmers and 14.4 % of public officers drank 3 bottles at a time. 10.5 % of teachers and 9.9 % of public officers drank above 10 bottles. 13.The variables which affect on drinking were sex(B=.1545), education(B=.1476), job(B=.1064), and age(B=.1052). These variables were significant in the level of 0.05 % and explanatory variance level was 18 %. 14.Government have to educate people and demonstrate the health hazards caused by smoking and over-drinking. Especially, No-smoking campaign for woman and education not to over drink for professional job workers are necessary.

  • PDF

한국재래닭의 ADSL 유전자 내 단일염기변이를 이용한 경제형질과의 연관성 분석 (Identification of Novel Single Nucleotide Polymorphisms on ADSL Gene Using Economic Traits in Korean Native Chicken)

  • 이진아;전세아;오재돈;박경도;최강덕;전광주;이학교;공홍식
    • 한국가금학회지
    • /
    • 제36권3호
    • /
    • pp.207-213
    • /
    • 2009
  • 퓨린 합성의 반응을 촉진시키며 뇌기능장애, 성장장애 그리고 에너지대사에 핵심적인 역할을 하는 ADSL(Adenylosuccinate lyase)의 exon 영역을 중심으로 PCR을 수행하여 DNA 염기서열 분석을 통해 한국재래닭에서 단일염기다형성을 확인하였다. 염기분석 결과 총 11개(intron 5: T7724C, C7732T intron 8: G10108T intron 9: A10356T, G10375A, A10402 intron 10: A12716T, T12717A intron 12: C15491T exon 13: C15542T, C15550T)를 확인할 수 있었으며 특히 exon 13지역의 변이들은 각각 아미노산이 바뀌는 missense mutation 임이 확인되었다(Alanine$\rightarrow$Valine, Proline$\rightarrow$Serine). 또한 C15542T 변이는 NCBI의 SNP 데이터베이스에 등록된 것으로 확인되었고, C15550T는 SNP 데이터베이스에 등록되지 않은 신규 변이지역으로 확인되었다. 이는 단백질 발현이 향상되는 3'UTR 지역 근처인 exon 13 부위이며 추가적으로 ADSL 유전자의 아미노산 변이가 닭 집단의 성장 및 에너지 대사와의 연관성 검증을 통해 본 연구 결과는 중요하게 활용될 것으로 기대된다.

한국판 식사태도검사-26(The Eating Attitude Test-26 : KEAT-26) 의 타당화 (A Validation of The Korean Version of Eating Attitude Test-26)

  • 이민규;고영택;이혜경;황을지;이영호
    • 정신신체의학
    • /
    • 제9권2호
    • /
    • pp.153-163
    • /
    • 2001
  • 본 연구는 KEAT-26의 변별 타당도를 알아보고 이 척도의 진단적(분류적) 효율성을 알아보기 위해서 이루어졌다. 참여자는 여성 식사장애 환자 108명, 체형관리센터에서 체형관리프로그램에 참여하고 있는 여성 179명, 체대운동여학생 120명, 일반여자대학생 227명 그리고 일반여자 183명(총 817명)이었다. 변량분석과 ROC(Receiver Operating Characteristic Curve) 곡선 분석을 통해서 이 척도의 타당화를 시도하였다. 그 결과 KEAT-26 총점수가 집단간에 통계적으로 유의한 차이를 보였으며, 사후 검증에서 식사장애 환자집단이 다른 모든 집단보다 KEAT-26 점수가 유의하게 높았다. 그리고 각 집단에 따른 KEAT-26의 4 개 하위 요인점수의 차이 검증에서 모든 하위요인들에서 집단의 주 효과가 유의하였으나, 사후검증에서 요인 IV의 변별력이 떨어졌다. ROC 곡선 분석을 통하여 이 척도의 분류적인 효용성과 최대의 가질 때의 절단접수를 알아본 결과 식사장애 환자와 정상인 집단을 분류할 때 평균 약 80%이상의 효용성이 있으나 식사장애 고위험 집단을 변별할 때는 평균 약 69%의 효용성을 보였다. 특히, 최고의 효용성을 보일 때의 절단점수를 효면, 식사장애환자와 체형관리자를 분류할 때 절단점이 25점, 식사장애환자와 일반 여자를 분류할 때 분류점수는 19 점, 삭사장애환자 대 체대운동여학생의 분류 점수는 23점, 식사장애환자 대 일반여대생의 절단점은 21점이었다. 이민규 등(1998)이 제안한 T점수 65에 해당하는 KEAT-26의 총점 22점을 절단점수로 했을 때 이 척도의 민감도 54%, 특이도 84%, 효율성은 평균 80% 이었다. 본 연구 결과 KEAT-26온 한국 사람이 겪고 있는 식사문제에 관련된 연구에 필요한 신뢰롭고 타당한 도구임을 밝혀졌다. 또한 본 연구결과는 이 척도가 임상적인 이용 뿐 만 아니라 역학조사 동의 목적으로 식사문제가 있는 사람을 선별하는데도 유용한 도구임을 지지해 준다.

  • PDF

DACUM 기법에 의한 1급 응급구조사의 직무분석 (Task Analysis of Paramedics of Korea Based on DACUM Method)

  • 배기숙;고봉연;이정은;이인모;최근명;김수태
    • 한국응급구조학회지
    • /
    • 제15권1호
    • /
    • pp.5-23
    • /
    • 2011
  • Objective : This study grasps specific task on paramedics who plays a great role in the emergency scene, thereby eliciting definition of job called paramedics and analyzing occupation by DACUM method. Thus, the aim is to suggest working-level guidelines on the task of paramedics. Methods : It targeted paramedics who are working at hospitals, fire stations, and industries in Seoul and Gyeonggi area from Oct. 11, 2010 to Nov. 30. A total of 608 copies of questionnaire were analyzed by DACUM method. A research tool on occupational analysis consisted of 8 pieces for duty, 43 pieces for task, and 149 pieces for task elements. In order to survey performance frequency, importance, and difficulty by element, each task was developed by this research team, and each task was analyzed and finally elicited through workshop of DACUM method. Results : The occupational definition of paramedics, which was defined through this DACUM, was elicited as 'professional job of performing emergency medical care on the scene, during transferring, or within medical institution in order to maintain life and prevent wound deterioration, targeting a person who is put in emergency situation.' Task element, whose performance frequency was indicated to be the highest, was in order of checking mental status($2.76{\pm}0.497$), checking vital signs($2.70{\pm}0.578$), and airway/c-spine immobilization($2.69{\pm}.546$). Especially, defibrillation stood at $2.23{\pm}.655$ points. Task element, whose performance frequency was low, was in order of caring sexual abuse victims($1.32{\pm}0.563$), performing cricothyrotomy($1.36{\pm}0.618$), and caring cardiac arrest victims($1.40{\pm}0.636$). Importance of task was in order of airway/c-spine immobilization ($2.88{\pm}0.338$), maintenance of respiration($2.88{\pm}0.351$), caring cardiac arrest victims($2.87{\pm}0.349$), and performing CPR($2.87{\pm}0.361$). Task element, whose importance is low, was indicated to be in order of enema($2.29{\pm}0.736$), urinary catheterization($2.35{\pm}0.664$), and nasogastric intubation($2.35{\pm}0.667$). Task element, whose difficulty was shown to be the highest, was indicated to be in order of caring cardiac arrest victims during pregnancy ($2.60{\pm}0.559$), caring cardiovascular injury($2.59{\pm}0.546$), and labor management($2.53{\pm}0.533$). Conclusion : Based on the results of this study, the job performance work table(Dacom chart) of paramedics is suggested to be used, thereby being applied to development in education and curriculum of paramedics. It is necessary to evaluate usefulness of the job performance work table by estimating effect of education for paramedics based on the job performance work table of paramedics.