• Journal of Periodontal and Implant Science
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• v.29 no.1
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• pp.31-40
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• 1999

Many factors may affect periodontal changes during the physiologic conditions of woman(e.g. puberty, menstrual cycle, pregnancy, menopause). Recently many research has focused on the immunological changes of host, but the exact mechanism is not clear. Collagen is a major constituent of periodontium, and collagenase specifically digests the collagen and plays a role in destruction of periodontal tissue. So, I suppose that it participates with the cytokines in the inflammation of gingiva and vascular response during the changes of female sex hormones. Because there are some evidences of the existence of the receptors of estrogen and progesterone in the gingiva, it may be a target tissue of female sex hormones. In this experiment, gingival fibroblast and periodontal ligament cell were cultured in the presence of various concentrations of estrogen or progesterone corresponding to the menstrual cycle and pregnancy. Collagenase activity of the supernatant of culture media was determined by Spectrophotometric collagenase assay. The enzyme activity was calculated by the % decrease of the coated collagen. 1. The estrogen at both concentrations had no effect on the activity of collagenase of the gingival fibroblast. 2. The progesterone had some effect on the collagenase activity of the gingival fibroblast at low and high concentration of menstrual cycle, and elevated the enzyme activity at all range of pregnancy concentrations. 3. In periodontal ligament cells, estrogen elevated the enzyme activity at the early pregnancy concentration and progesterone elevated at the concentration just before menstruation. In this experiment, pregesterone elevated the collagenase activity of gingival fibroblast and periodontal ligament cells. But the mechanism of the up-regulation of the enzyme activity was not confirmed. The more experiments of direct effect of progesterone on gingival at the molecular level(e.g. northern blot analysis) can reveal the exact mechanism.

• Women's Health Nursing
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• v.18 no.3
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• pp.170-179
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• 2012

Purpose: The purpose of this study was to identify menstrual distress, coping method and relief of symptoms among female nurses who worked with 3-shift. Methods: A total of 185 participants were recruited from November 18, 2011 to January 30, 2012. The measurement included menstrual distress and coping method questionnaire and relief of symptoms. The data were analyzed using t-test, ANOVA, Pearson's correlation coefficients with SPSS 19.0 Results: The level of menstrual distress was moderate (mean 3.0), and there were significant differences in menstrual distress by age, education, stress, regularity of menstrual cycle. Among the coping methods, coping according to menstrual cycle specific was the most frequently used, followed by active recognizing coping, active behavioral coping, and avoidance coping. Among the degree of symptom relief, symptom relief score was the highest when used coping according to menstrual cycle specific. Menstrual distress was associated with stress, adequate amount of sleep, dysmenorrhea and number of coping method total. Conclusion: Nurses experienced moderate levels of menstrual distress and used various types of coping to relieve it. There is a need for hospital nurses to develop an effective nursing intervention to relieve the menstrual distress and utilize active coping methods.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.1
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• pp.56-69
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• 2012

Objectives: This study was conducted to investigate the relationship between menstrual conditions and items of health checkup examinations in female university students for prediction of reproductive health. Methods: Data from the 2011's medical examination participants(990 students among total 1,699 students) of ${\bigcirc}{\bigcirc}$ University University in Korea were analyzed for this study. Menstrual condition, Sa-sang constitution and other surveys were checked through self-administered questionnaire, health checkup were measured anthropometric variables, CBC, B/C and U/A. Results: In the 46.4% of total participants appeared menstrual disorder of menstrual cycle or menstrual amount, the irregular period of menstrual cycle have a influence on menstrual amount. stress was relatively heavy factor of causing irregularity of menstrual cycle and amount, RBC, cholesterol, ABO type and Sa-sang constitution had some connection with menstrual amount. Conclusions: Among the items of health checkup examinations, stress, RBC, cholesterol, ABO type and Sa-sang constitution were related with the change of menstrual cycle and amount.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.62-70
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• 2011

Objectives: The purpose of this study is to investigate the relationship between cold hypersensitivity and common health indexes including dyspepsia, headache, defecation, leucorrhea, and menstruation in young women. Methods: 40 outpatients who visited Kangnam Kyung-Hee Oriental Hospital from January, 2010 to November, 2011 were analyzed. The experimental group consisted of 20 patients diagnosed with cold hypersensitivity, while the control group consisted of 20 patients who were not. All patients were subjected to Digital Infrared Thermal Imaging(DITI), and those with thermal difference greater than $2^{\circ}C$ between anterior thigh and top of feet were diagnosed with cold hypersensitivity. The subjective characteristics of dyspepsia, headache, defecation, leucorrhea, and menstruation were obtained through inquiry by residents at the hospital. The relationship between cold hypersensitivity, dyspepsia, headache, defecation, leucorrhea, and menstruation was analyzed with Independent T-test using SPSS for Windows (version 17.0). Results: Means of defecation, leucorrhea, dysmenorrhea in cold hypersensitivity group were higher than control group without significant statistical difference. Dyspepsia appeared statistically higher in experimental group with significance while headache was the same in both groups. Means of menstrual cycle and menstrual coagulation were higher in non-cold hypersensitivity group, but there was no statistical difference. Conclusions: Results suggest that dyspepsia is common in cold hypersensitivity and treatment of cold hypersensitivity may relieve accompanying digestive problems.

• Journal of Veterinary Science
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• v.21 no.3
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• pp.48.1-48.18
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• 2020

Background: Mature oocytes at the metaphase II status (MII-stage oocytes) played an important role in assisted reproductive technology in non-human primates. Objectives: In order to improve the proportion of MII-stage oocytes retrieval, three different superovulation protocols were performed on 24 female cynomolgus monkeys. Methods: All the monkeys received once-daily injection of follicle-stimulating hormone (25 international unit [IU]) on day 3 of the menstruation, 3-day intervals, twice daily for 8-12 days until the time of human chorionic gonadotropin (1,500 IU) injection, on the 14-17th day of menstruation collecting oocytes. The difference between protocol I and protocol II was that 0.1 mg the gonadotropin-releasing hormone agonist was injected on day 1 of the menstruation, while the difference between personalized superovulation protocol and protocol II was that oocytes could be collected on the 14-17th day of menstrual cycle according to the length of each monkey. Results: The total number of oocytes harvested using the personalized superovulation protocol was much higher than that using protocol I (p < 0.05), and the proportion of MII-stage oocytes was significantly greater than that from either superovulation protocol I or II (p < 0.001 and p < 0.01 respectively), while the proportion of immature oocytes at the germinal vesicle was less than that from superovulation protocol I (p < 0.05). Conclusions: The personalized superovulation protocol could increase the rate of MII-stage oocytes acquired, and successfully develop into embryos after intracytoplasmic sperm injection, and eventually generated fetus.

• Women's Health Nursing
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• v.14 no.4
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• pp.314-322
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• 2008

Purpose: Dysmenorrhea is one of the most common gynecologic complaints of young women. This study investigated the changes in the menstrual cycle during test evaluations according to perfectionism and testing anxiety among high school girls in order to provide information for care of dysmenorrhea. Method: Data collection was done from July 14 to 18, 2008 by self administered questionnaires with 300 high school girls. Result: The subjects experienced amenorrhea(35.3%), changes in the menstrual cycle(66.3%), changes in menstrual duration(50.0%), changes in amount of menstruation(47.7%), and increases in menstrual pain during testing evaluations. There were significant differences in changes of menstrual patterns, physical symptoms, and menstrual pain during test evaluations between a high perfectionist group and low perfectionist group. Also, there were significant differences in changes of menstrual patterns, physical symptoms, and menstrual pain during test evaluations between a high testing anxiety group and low testing anxiety group. Perfectionism and testing anxiety showed a positive relationship with changes in menstrual patterns, physical symptoms, and menstrual pain. Conclusion: As perfectionism and testing anxiety seem to contribute to changes in the menstrual cycle during test evaluations, school health-care providers should screen routinely for dysmenorrhea and give more attention to health education on this topic to girls.

• Journal of Oriental Medical Thermology
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• v.2 no.1
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• pp.6-10
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• 2003

Purpose : Man is a homoiothermal animal. But by various causes, body temperature can be changed to $1^{\circ}C$. Basal temperature is a very useful method in many fields of OB&GY area. So we observed the change of body temperature according to menstrual cycle. Materials and Methods : We observed 3 female who have very regular 30 days menstrual cycle. The Observation started before the onset of menstruation and body temperature was checked in the same time (11:00 am) of a day. To evaluate the change of body temperature, we examined three points of body. And to observe the body temperature we used the D.I.T.I(Dorex, Inc., USA). Results : On this study we couldn't find the typical biphasic change of body temperature but most of the materials showed the elevation of body temperature on the 14th day. Between the examined three points, the lowest point was showed more typical biphasic change of body temperature.

• Journal of Chest Surgery
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• v.41 no.2
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• pp.285-288
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• 2008

Recurrent pneumothorax was associated with the menstrual cycle in two women 20 to 30 years age; this is referred to as catamenial pneumothorax. This form of pneumothorax occurs within 72 hours before or after the onset of menstruation. The pathophysiology underlying this condition is unknown. We report here on two cases of catamenial pneumothorax that were successfully treated by partial resection of the diaphragm.

• Korean Journal of Adult Nursing
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• v.14 no.1
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• pp.144-153
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• 2002

Purpose: The purpose of this study was to describe the premenstrual syndrome and the relationships among premenstrual syndrome, automatic thought, and perfectionism. Methods: The 164 subjects were selected from a nursing college in Tae-Jeon. The data were collected using the PAF, ATQ-N, and MPS from April 10th to May 10th, 2001. Results: The results of this study were as follows : 1. There was no significant difference in premenstrual syndrome due to menarche, duration of menstruation, and menstrual cycle, but significant difference in premenstrual syndrome due to amount of menstruation and regularity of menstrual cycle. 2. The subjects experienced mild premenstrual syndrome. The severe premenstrual syndromes above the mean were who subjects reported general physical discomfort, fatigue, low mood and loss of pleasure, lability and atypical depressive features, et. al., and those below the mean experienced hostility/anger, increased well-being, miscellaneous mood/behavior change, impulsive syndrome and miscellaneous physical changes, et. al. 3. The score of mean premenstrual syndrome was 236.55, that of automatic thought was 31.41 and that of perfectionism was 185.97. The premenstrual syndrome score was similar to those of other studies and subjects had low automatic thought and moderate perfectionism. 4. There were significant correlations among premenstrual syndrome, automatic thought, and perfectionism (P <. 001). 5. Automatic thought and perfectionism accounted for 17 percent of premenstrual syndrome. Conclusions: For future research, it was recommended that the study to identify major factors affecting premenstrual syndrome and the relationships between them with various subjects should be done and effective nursing intervention for premenstrual syndrome should be developed.

• Women's Health Nursing
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• v.10 no.3
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• pp.226-234
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• 2004

Purpose: This study was to examine health status, reproductive health problems and the degree of prenatal management in working women. Method: The subjects were 902 married working women among 2,000 women selected by cluster sampling. The work area was classified to product factory, school, office, etc. After an Informed consent was obtained, participants were asked to fill out a self-administered questionnaire. The instruments included a questionnaire, parity check list, menstrual problems and gynecologic problem check list. Result: Many women have experienced menstrual cycle change during the past year. There was a significant difference in general health, menstrual regularity, reproductive health and prenatal management by occupation type. 40.6 percent of the subjects have gynecological problems such as menstrual cycle change, perineal inflammation, irregular vaginal bleeding, amenorrhea, ovarian/uterine disease, infertility, or abortion. Prenatal care was received in only 28.5% of the total subjects. In addition, 16.3% answered they had experienced low birth weight babies. Conclusion: We can conclude that working woman have changes in menstruation cycle and in reproductive health status. Therefore, we suggest that some occupational characteristics may affect subject's reproductive health, these should be clear and avoided as much as possible.