• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.23-31
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• 2004

Background: Obesity is associated with menstrual disorder. Especially, upper-body obesity affects on female reproductive function. Objectives: The goals were to investigate relation between fat distribution and menstrual disorder in obese pre-menopausal Korean females. The hypothesis were tested that there is a relation between upper body obesity and menstrual disorder. Design: A cross-sectional evaluation of 66 Females (baseline age $32.15{\pm}7,32)$ with body mass index $31.22{\pm}4.05\;kg/m^2$. Body composition was measured using bioimpedence analysis (BIA) and anthropometry was done by same observer. VAS and Multidimensional verval rating scale(MVRS) were checked for menstrual pain. Dual-Energy X-ray Absorptiometry (DXA) was measured for evaluating body fat distribution. Menstrual disorder and body fat distribution were compared using statistical methods. Results: TLFR and WH ratio was higher in menstrual cyclic disorder group than controls. There was negative relationship between VAS and TLFR. Conclusions: The data shows that disorder of menstrual cycle was associated with upper body obesity. WH ratio could be one of the factor of menstrual disorder. VAS was correlated with lower body obesity. Further studies for role of upper body fat distribution on female reproductive function and relationship between menstrual pain and fat distribution thought to be needed.

• Clinical and Experimental Pediatrics
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• v.49 no.12
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• pp.1257-1262
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• 2006

The age of puberty represents a very critical time in the life history of every young woman. The menarche stands as primary indicator of the onset of sexual maturation in females. By late adolescence, 75% of girls experience some problem associated with menstruation. Delayed, irregular, painful, and heavy menstrual bleeding are leading reasons for physician office visits by adolescents, and dysmenorrhea is the leading reason for school absenteeism among girls. This article discusses normal menstrual function during adolescence, then reviews the clinical presentation, evaluation, and management of adolescent dysmenorrhea, dysfunctional uterine bleeding, amenorrhea, and polycystic ovary syndrome.

• Journal of Nutrition and Health
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• v.32 no.1
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• pp.50-63
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• 1999

This study was conducted with 20 female gymnasts and 23 age-matched controls to examine the relationship of diet, menstrual function and bone mineral density (BMD). The results obtained are summarized as follows : Energy intake of gymnasts was 968.9$\pm$421.4kcal, and energy expenditure was 2091.4$\pm$361kcal showing negative energy balance(-1,122.5$\pm$534.6kcal). The average intakes of calcium, iron, vitamin A, thiamin, riboflavin and niacin did not meet the Recommended Dietary Allowances for their age groups. Mean age at menarche in gymnasts is 15.8$\pm$1.2 years compared with 11.8$\pm$2.8 years in age-matched controls. The profile of estradiol, progesterone, and luteinizing hormone was lower than age-matched controls but not significant. Athletic amenorrheic gymnasts(n=12) have the menstrual irregularity(n=10) and amenorrhea(n=2). A number of variables as such nutritional deficiency in diet, negative energy blasnce and hypogonadotropic hormonal status were included. The bone mineral density (BMD) of female gymnasts were significantly higher than controls for the lumbar neck(p<0.001), trochanter(p<0.01), and Ward's triangle(p<0.001), but there were no significant differences for the lumbar spine and forearm. The lumbar spine BMD had a positive correlation with age and lean body weight. The femoral neck BMD was significantly associated with age, group and lean body mass. The trochanter BMD had significant relationship with group, body mass index, energy expenditure and follicular stimulating hormone. Ward's triangle BMD were related to body mass index and follicular stimulating hormone. The significant association was deterced between forearm BMD and age and lean body weight. The major finding of this investigation is that the BMD of gymnasts were higher than age-matched controls despite the fact that gymnasts as a group had inadequate dietary calcium and a higher propensity to have an interruption of their menstrual cycle. These data indicate that grymnsts involved in sports producing significant impact loading on the skeleton had greater femoral neck, trochanter and Ward's triangle bone density than age-matched controls.

• Clinical and Experimental Reproductive Medicine
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• v.17 no.2
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• pp.159-165
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• 1990

It has been reported that endogenous opioid peptides play a role in the control of the reproductive function. The goal of this study was to evaluate changs in the serum levels of ${\beta}$-endorphin during hyperstimulated menstrual cycle and their relationship to serum prolactin levels. Serum ${\beta}$-endorphin and prolactin levels were measured during menstrual cycles of 10 normal cylic women hyperstimulated by human menopausal gonadotropin (HMG) and of 10 women by clomiphene/HMG among in vitro fertilization candidates. The results were summarized as follows. 1. In clomiphene/HMG hyperstimulated menstrual cycle the mean serum ${\beta}$-endorphin level insignificantly on 2 day before aspiration of oocyte compared to basal level and reached maximum level on 1 day after aspiration. 2. There was a significant peak of the mean serum ${\beta}$-endorphin level on 1 day before aspiration in HMG hyperstimulated menstrual cycle. 3. On the same day from aspiration, there was no significant differences in the mean serum ${\beta}$-endorphin levels between HMG and clomiphene/HMG hyperstimulated cycles. 4. No significant correlation was noted between serum ${\beta}$-endorphin levels and prolactin levels.

• The Journal of Korean Obstetrics and Gynecology
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• v.26 no.2
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• pp.46-65
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• 2013

Purpose: Generally menstrual disorder caused by functional deficiency of ovary is not treated clinically because it manifests as normal process of growth. In this study we collected experimental group having several or severe menstrual disorder and we tried to find out whether there is any relationship between menstrual disorders and the function of Thoroughfare and Conception vessels or not. Methods: First, this study was researched to learn the meaning and the symptoms of 'the emaciation of Thoroughfare and Conception vessels', and to learn the relationship between menstrual disorders and 'the emaciation of Thoroughfare and Conception vessels' through literature review. And we set up a experimental group who have two or more menstrual disorders or severe degree of menstrual disorders(N=97) and control group who don't have menstrual disorders(N=97) as a result of the menstruation survey. Afterwards we conducted the DSOM in both experimental group and control group. Results and Conclusions: The meaning of 'the emaciation of Thoroughfare and Conception vessels' is deficiency of qi and blood from the Thoroughfare and Conception vessels. As a result, the female reproductive system is difficult to be worked properly with deficiency of skin, muscles, bone, and vessels. Symptoms of the emaciation of Thoroughfare and Conception vessels are classified into drying, skinny body, feeling of cold, menstrual disorders, pain and personality traits. In this study, severity of drying, skinny body, feeling of cold, menstrual disorders, pain and personality traits is significantly higher in experimental group than in control group. Like this, symptoms of 'the emaciation of Thoroughfare and Conception vessels' appear with menstrual disorders because disorder of circulation is occurred by qi and blood deficiency of Thoroughfare and Conception vessels. It is appropriate to identify this case as 'the emaciation of Thoroughfare and Conception vessels' pattern and necessary to treat actively through regulating qi and blood in advance.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.101-110
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• 2007

Purpose: Oligomenorrhea is clinically important because it can be progressed to amenorrhea. The purpose of this study is to analyse Autonomic Nerve Function of some oligomenorrheic patients by using HRV(Heart Rate Variability). Methods: We studied 35 patients visiting OO Oriental Hospital from 1st November 2006 to 31th May 2007. One woman who takes antidepressant is excluded. 17 oligomenorrheic group and 17 normal menstrual cycle group were compared with HRV. The SPSS 12.0 for windows was used to analyze the data and Mann Whitney U-test were used to verify the results. Results: Mean PR, LF norm, LF/HF ratio of oligimenorrheic group are higher than normal menstrual cycle group. But there is no statistically significance. SDNN, RMS-SD, ln TP, ln VLF, ln LF, ln HF, HF norm of oligimenorrheic group are lower than normal menstrual cycle group. But there is no statistically significance. Conclusion: It can be suggested that oligomenorrhea can be related to increased activities of sympathetic nerve and decreased activities of general autonomic nerve function. But, we need study with more subjects for settling this.

• Clinical and Experimental Reproductive Medicine
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• v.46 no.1
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• pp.1-7
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• 2019

With the progress of regenerative medicine, mesenchymal stem cells (MSCs) have received attention as a way to restore ovarian function. It has been reported that MSCs derived from bone marrow, adipose, umbilical cord blood, menstrual blood, and amniotic fluid improved ovarian function. In light of previous studies and advances in this field, there are increased expectations regarding the utilization of MSCs to restore ovarian function. This review summarizes recent research into potential applications of MSCs in women with infertility or primary ovarian insufficiency, including cases where these conditions are induced by anticancer therapy.

• Nutritional Sciences
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• v.8 no.2
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• pp.118-124
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• 2005

To examine the eating attitudes, weight concerns, dietary intake, and menstrual function of Korean female elite athletes, 109 subjects in seven sports disciplines (rhythmic gymnastics, synchronized swimming, badminton, volleyball, Taekwondo, field hockey, and soccer) responded to a questionnaire consisted of three parts; eating attitudes and behavior(Eating Attitude Test-26; EAT26), body weight perception (Body Dissatisfaction Index: BDI) and weight control behavior, and menstrual history and status. They also recorded three-day dietary intake. Body weight (43.6$\pm$4.3 kg) and body mass index (16.7$\pm$1.4 kg/$m^2$) in rhythmic gymnasts were lower than those in other athletes (P<0.05). EAT26 scores were not different among sport events (12.3$\pm$6.5 total), however, eating disturbances (EAT26 score$\geq$20) were highly prevalent in aesthetic athletes ($30\%$) than in others ($5\%$). More than half of the athletes perceived themselves overweight and four fifth of the athletes desired to reduce weight about 4.4 kg. The gymnasts consumed the lowest caloric intake (1028:t371) while the volleyball players did the highest (2995$\pm$342 kcal/d) (P<0.05). The BDI score was not different among sport events. Three fourth of the athletes experienced weight control, and the most frequently used weight reduction method was exercise followed by using robber suits, diet, and sauna. About $40\%$ of the subjects reported irregular menstrual cycles, but menstrual dysfunction ($\leq$6 menses/yr) was only $5\%$. Generally, the Korean female elite athletes desired to reduce weight from their current body weight. No differences in eating attitude and body dissatisfaction were noticed among athletic disciplines. However, eating disturbances were highly prevalent in aesthetic athletes who also reported much less energy intake than the recommend daily energy intake. It appeared that weight reduction methods were not properly practiced in these population. Menstrual dysfunction was minimally reported.

• Journal of the Korean Society for information Management
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• v.40 no.4
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• pp.1-31
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• 2023

This study conducted user experience evaluation by introducing various text mining techniques along with topic modeling techniques for mobile menstrual cycle measurement applications that are closely related to women's health and analyzed the results by combining them with a honeycomb model. To evaluate the user experience revealed in the menstrual cycle measurement application review, 47,117 Korean reviews of the menstrual cycle measurement application were collected. Topic modeling analysis was conducted to confirm the overall discourse on the user experience revealed in the review, and text network analysis was conducted to confirm the specific experience of each topic. In addition, sentimental analysis was conducted to understand the emotional experience of users. Based on this, the development strategy of the menstrual cycle measurement application was presented in terms of accuracy, design, monitoring, data management, and user management. As a result of the study, it was confirmed that the accuracy and monitoring function of the menstrual cycle measurement of the application should be improved, and it was observed that various design attempts were required. In addition, the necessity of supplementing personal information and the user's biometric data management method was also confirmed. By exploring the user experience (UX) of the menstrual cycle measurement application in-depth, this study revealed various factors experienced by users and suggested practical improvements to provide a better experience. It is also significant in that it presents a methodology by combines topic modeling and text network analysis techniques so that researchers can closely grasp vast amounts of review data in the process of evaluating user experiences.

• Journal of Korean Academy of Nursing
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• v.29 no.4
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• pp.829-840
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• 1999

This study was conducted to construct a hypothetical model of depression in Korean adolescent women and validate the fit of the model to the empirical data. The data were collected from 345 high school girls in Seoul, from May 1 to June 30, 1998. The instruments were the Body Mass Index, Physical Satisfaction Scale, Family Adaptatibility and Cohesion Evaluation Scale III, Family Satisfaction Scale, CES-D and School Adptation Scale. The data were analyzed using descriptive statistics with the pc -SAS program. The Linear Structural Relationship(LISREL) modeling process was used to find the best fit model which would predict the causal relationships among the variables. The overall fit of the hypothetical model to the data was moderate ［X$^2$＝69.6(df＝17, p＝.000), GFI ＝0.95, AGFI＝0.90, RMR＝0.087, NNFI＝0.86, NFI＝0.90］. The predictable variables, especially menstrual symptoms, physical symptoms and family function, had a significant direct effect on depression. but school life adaptation did not have a significant direct effect. These variables explained 18.1% of the total variance.