• 한방재활의학과학회지
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• 제19권1호
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• pp.155-167
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• 2009

Objectives : Psychological comorbidities are high in patients with obesity and are associated with a variety of medical and dietary problems. This study aims to examine the association between psychological factors and obesity. Methods : This study was performed in pre-menopausal obese($BMI{\geq}25kg/m^2$, waist circumference ${\geq}85cm$) women in Seoul, in 2008 (n=35). Every patient underwent the obesity treatment program. The program included dietary and exercise education, and abdominal mesotherapy for 6 weeks. Simple anthropometry including weight, BMI and Computed Tomography (CT) including Subcutaneous adipose tissue (SAT), Visceral adipose tissue (VAT) and Visceral adipose tissue/Subcutaneous adipose tissue ratio (VSR) were done. To assess psychological factors, the Rosenberg self-esteem scale (SES) questionnaire, Beck depression inventory (BDI) questionnaire and stress response inventory(SRI) questionnaire were administered. Results : 1. All of the obesity indicators (except VSR) decreased significantly after the obesity treatment program. 2. There was a significant relationship between self esteem (SES score) and visceral obesity (VAT and VSR) measured at the end of the program. 3. During the intervention, the more weight, BMI, and subcutaneous adipose tissue decreased, the more self-esteem (SES) increased. There was no relationship between depression (BDI) and obesity. And the change in stress response (SRI) was associated with the change of deep subcutaneous adipose tissue and total abdominal adipose tissue. Conclusions : This study proves that visceral obesity may contribute to low self-esteem, and there is a possibility that the other psychological factors could also be related with obesity in Korean obese women. Individualised antiobesity therapy may be required depending on the patient's psychological characteristics and weight loss could be helpful in order to treat psychological problem in obese patients.

• 생물정신의학
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• 제23권4호
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• pp.199-204
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• 2016

Objectives Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is to examine whether menopause is related to cognitive decline among women with depressive disorders. We hypothesized that postmenopausal depressed women show generally poorer performance than premenopausal depressed women on various cognitive function tests. Methods With a retrospective chart review, we identified a total of 87 female patients (45 premenopausal patients and 42 postmenopausal patients) who were hospitalized with depressive disorders from 2000 to 2016. Demographic and clinical variables and cognitive test results were compared between two groups. Results Education year is longer in premenopausal group than postmenopausal group whereas clinical characteristics (illness duration, recurrence, and symptom severity) and mean Intelligence Quotient (IQ) were similar between two groups. The postmenopausal group took longer time for Bender-Gestalt Test (BGT) recall, Trail Making Test (TMT)-A, and TMT-B than the premenopausal group. After controlling for age and education, significant difference was remained for BGT recall (p = 0.029). Conclusions Postmenopausal state may be related with decline of visuospatial memory function, in particular, among depressed female patients. Other areas of cognitive function including complex attention, verbal memory, auditory memory, and working memory might be interpreted while considering age and education level.

• Journal of Ginseng Research
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• 제37권1호
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• pp.30-36
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• 2013

The aim of this review was to assess the effectiveness of ginseng as a treatment option for managing menopause symptoms. We searched the literature using ll databases from their inception to 26 September 2012 and included all randomised clinical trials (RCTs) that compared any type of ginseng to a placebo controls in postmenopausal women. The methodological quality of all studies was assessed using a Cochrane risk of bias tool. Four RCTs met our inclusion criteria. Most RCTs had high risk of bias. One RCT showed that Korean red ginseng (KRG) significantly improved sexual arousal and global health compared with placebo. Another RCT reported the superiority of KRG over placebo for treating menopause symptoms on Kupperman's index and menopausal rating score. The third RCT failed to show a significant effect of KRG on hot flash frequency compared to placebo. The fourth RCT found beneficial effects of ginseng compared to placebo on depression and well-being. In conclusion, the evidence on ginseng as an effective treatment for managing menopause symptoms is limited. Most of the RCTs are burdened with a high risk of bias. Thus firm conclusions cannot be drawn. Rigorous studies seem warranted.

• Journal of Menopausal Medicine
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• 제24권3호
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• pp.143-149
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• 2018

Lack of adequate sleep has become increasingly common in our 24/7 modern society. Reduced sleep has significant health consequences including metabolic and cardiovascular disorders, and mental problems including depression. In addition, although the increase in life expectancy has provided a dream of longevity to humans, the occurrence of osteoporosis is a big obstacle to this dream for both male and female. It is known that insomnia and bone health problems, which are very critical conditions in human life, interestingly, share a lot of pathogenesis in recent decades. Nevertheless, due to another side effects of the synthetic drugs being taken for the treatment of insomnia and osteoporosis, patients have substantial anxiety for the safety of drugs with therapeutic expectation. This review examines the pathogenesis shared by sleep and osteoporosis together and herbal medicine, which has recently been shown to be safe and efficacious in the treatment of both diseases other than synthetic drugs. We suggestions for how to treat osteoporosis. These efforts will be the first step toward enabling patients to have comfortable and safe prescriptions through a wide selection of therapeutic agents in the future.

• Journal of Menopausal Medicine
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• 제23권3호
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• pp.156-159
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• 2017

Some species of traditional herbal medicine has a history of use, most traditional natural herbs have been used for various diseases such as diabetes, hypertension, and obesity. Among them, Passiflora incarnata L. is a traditional natural medicine, flowers as well as berries, roots, and leaves have been used as a medicine. It has been used as a natural medicine for the treatment of insomnia and anxiety for a longtime in Europe, and it has been used primarily for sedation tea in North America. Moreover, Passiflora incarnata L. is widely used anti-asthmatic, analgesic and sedation in Brazil. In other words, Passiflora incarnata L. has been used to treat a sedative, dysmenorrhea, insomnia, cancer, etc. in many countries. Present review of the plants showed a wide range of pharmacological activity in anxiolytic relax the clinical disease, such as anti-inflammatory, anxiety and antioxidant. In addition, Passiflora incarnata L. affects menopause symptoms such as vasomotor symptoms, insomnia, and depression. This review aims to provide the latest information on specific functional components of Passiflora incarnata L. especially the results of clinical trials will provide new insights into opportunities for the future development of natural medicines and doors will be used for purposes of analysis.

• 생물정신의학
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• 제6권2호
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• pp.235-239
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• 1999

본 연구는 폐경기 여성에서의 에스트로젠 치료에 따른 우울정도와 주의집중력의 차이를 평가하기 위해 폐경이 된 지 1년이 지난 폐경기 여성을 대상으로 사용군과 비 사용군으로 나누어 각각 30명을 대상으로 했다. 검사 도구는 한흥무 등(1986)이 표준화 한 Beck의 Beck depression inventory(BDI)를 사용하여 사용군과 비사용군으로 나누어 평가하였다. 그리고 주의 집중력의 평가는 K-WAIS(염태호 등 1992)의 소검사 항목인 숫자외우기와 바꿔쓰기을 사용하였다. 에스트로젠 사용군과 비사용군에서 각각의 검사 항목에 대해 t-test로서 유의한 차이가 있는지 비교하였다. 더불어 사용군과 비사용군에서 혈중 에스트라디올 농도를 측정하여 각 검사항목과 상관관계가 있는지 Pearson's correlation(r)를 통해 확인하였다. 결과는 BDI와 숫자외우기 중 바로 따라 외우기에서만 유의한 차이가 있었으며 다른 항목에서는 차이가 없었다. 그리고 혈중 에스트라디올 농도와 검사 항목간의 유의한 상관관계는 없었다. 본 실험을 통해 에스트로젠이 폐경기 여성에서 우울증상의 경감에 효과적이나 기억력 및 주의집중력에는 효과가 없음을 확인할 수 있었다.

• 대한한방부인과학회지
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• 제35권3호
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• pp.105-121
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• 2022

Objectives: It is a statistical analysis study to examine the results of CaPSPI (Diagnostic System for Climacteric and Postmenopausal Syndrome Pattern Identification), developed for objective defecation of climacteric and postmenopausal syndrome. Methods: Total 341 people's questionnaire responses were statistically analyzed. 275 people involved in developing CaPSPI 2018 (E) and 146 people involved in 2019-2020 study of research1,3). Results: The frequency of diagnosis for examination was the highest at liver depression, 93.8% for 320 times, the lowest at heartheat, 62.8% for 214 times. The frequency of treatment for examination was the highest at liver depression, 54.3% for 185 times, and the lowest at dual deficiency of heart-spleen, 16.7% for 57 times. The diagnosis ratio was the lowest at dual deficiency of heart-spleen, 19.72%, and the highest at liver depression, 57.81%. As a result of comparing these diagnoses with the Kupperman's index, all showed significant differences. As a result of comparing these disease elements, all showed significant differences. The correlation between diagnosis and dialectic elements was found to have similar results with the korean medical pathology, and in 7 dialectics except for heartheat, the treatment version was more severe or progressing to perjury than for examination. Conclusions: The CaPSPI shows the characteristics of korean medicine well, and it is needed to utilize the high correlative disease elements to upgrade the system.

• 정신신체의학
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• 제25권2호
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• pp.176-184
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• 2017

연구목적 중년 우울증 여성은 안면 홍조 증상을 자주 경험한다. 우울증과 안면 홍조 간의 연관성은 아직 명확하지 않다. 따라서, 본 연구에서는 안면 홍조가 있는 우울증 여성과 안면 홍조가 없는 우울증 여성을 대상으로 호르몬 농도, 기능적 신체 증상, 폐경에 대한 태도 및 스트레스대처 방식을 비교하여 그 특성에 대해 알아보고자 하였다. 방 법 안면 홍조가 있는 우울증 여성 33명과 안면 홍조가 없는 우울증 여성 33명이 연구에 참여하였다. 안면 홍조 증상은 일주일에 걸쳐 전향적으로 일일 증상 척도를 통해 확인하였다. 연구 대상자의 스트레스 대처 방식은 스트레스 대처 방식 설문지를 통해 평가하였다. 신체 증상은 환자 건강 설문지(Patient Health Questionnaire-15, PHQ-15)로 평가하였다. 성 호르몬 농도는 방사성면역분석법으로 측정하였다. 간편 세계보건기구 삶의 질 평가도구(Brief World Health Organization Quality of Life Assessment Instrument, WHOQOL-BREF)를 이용하여 삶의 질을 평가하였다. 결 과 스트레스 대처 방식에 있어서, 안면 홍조가 있는 우울증 여성이 문제-중심의 대처 방식과($13.15{\pm}3.17$) 사회적 지지에 대한 탐색($11.83{\pm}2.84$) 항목이 안면 홍조 증상이 없는 우울증 여성에 비해 적었다(각각 $15.17{\pm}3.1$, p=0.028 ; $14.25{\pm}3.22$, p=0.009). 안면 홍조가 있는 우울증 여성이 폐경 후에 대하여 상대적으로 부정적 태도를 보였으나, 통계적 유의성은 근사치로 불충분하였다(p=0.059). 본 연구에서는 PHQ-15로 평가한 신체 증상과 성호르몬 농도에서 두 군 간의 차이를 발견하지 못 하였다. WHOQOL-BREF에 따른 사회적 대인 관계의 점수는 안면 홍조가 없는 군보다($9.71{\pm}1.65$ ; p=0.044) 안면 홍조가 있는 군에서($8.62{\pm}2.04$) 유의하게 낮았다. 결 론 우울증이 있는 중년 여성에서, 안면 홍조 증상은 스트레스에 대한 대처 방식의 영향을 받는 것으로 나타났다. 우울증 여성에서 안면 홍조 증상은 삶의 질에 부정적 영향을 주므로, 임상가는 안면 홍조가 있는 우울증 환자에서 적극적으로 안면 홍조에 대하여 치료적인 접근을 해야 할 것이다. 항우울제 혹은 소량의 호르몬 치료에 반응이 없는 우울증 환자에서, 인지 행동 치료 또는 스트레스 관리가 효과적일 수 있겠다. 추후 안면 홍조 및 우울증과 관련된 위험 요인에 대한 인과 관계를 명확하게 하기 위해서는 객관적인 방법을 통한 종적 연구가 필요할 것으로 생각된다.

• 융합정보논문지
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• 제8권1호
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• pp.59-67
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• 2018

본 연구의 목적은 불쾌증상이론에 근거하여 폐경기 이후 여성의 우울증상에 영향을 미치는 융합적 요인을 분석하기 위하여 시행되었다. 연구 방법은 제 6기 2015년 국민건강영양조사 자료를 사용하여 분석한 이차 자료 분석 연구이다. 폐경을 경험한 1,298명을 대상으로 우울 증상, 생리적 요인, 상황적 요인 및 심리적 요인을 조사하였다. 연구 결과, 우울 증상에 영향을 미치는 예측요인은 소득수준(${\beta}=-.14$, p<.001), 건강상태(${\beta}=.24$, p<.001), 스트레스(${\beta}=-.20$, p<.001)로 나타났다. 모형의 설명력은 14.1%로 통계적으로 유의하였다. 이와 같은 연구결과는 바탕으로 폐경기 이후 여성의 우울 증상을 개선시키기 위해서는 소득수준, 건강상태, 스트레스를 고려한 간호중재가 필요하다.

• 대한간호학회지
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• 제7권1호
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• pp.73-79
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• 1977

This study was carried on between June first and July thirty-first 1976 using as subjects women living in the areas of Pusan, Kyoung Sang Buk Do and Kyoung Sang Nam Do. The subjects were divided into 3 groups according to different environments and styles of life, namely married life, widowhood and religious life and according to ages ranging between 45 and 55. Each of these 3 groups of women of .menopausal age consisted of 50 persons and totalling a group of 150. The subjects were chosen according to random sampling and the Cornell Medical Index was applied to discover physical and mental health status with the following results : 1. The total mean scores for complaints in the group of widows was 46.00, in the group of Married women was 37.10 and in the Sisters was 34.30 showing highest scores for the widows and lowest for the Sisters. 2. The mean score percentages for physical and mental complaints 28.80 and 16.50 respectively for the Widows:27.00 and 10.80 for the Married and 24.30 and 10.20 for the Sisters. 3. The highest number of mean scores for physical items was for digestive system complaints which showed a score of 5.04, 4.78 and 4.90 respectively for Widows, Married women and Sisters among the psychic status items all 3 groups showed highest scores for complaints of inadequacy: 5.52, 3.40 and 3.64 respectively. 4. In comparing the 2 groups of Married women and Widows, the highest significant differences appeared in the items of depression and sensitivity but there was also some significant difference in the items of inadequacy, anger, miscellaneous diseases and genito-urinary system complaints. 5. In comparing the Married women and Religious groups the highest significant differences according from the highest were as follows : cardiovascular system, sensitivity, tension, nervous system, frequent illnesses and anxiety.