• Title/Summary/Keyword: memory effect function

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Ameliorating Effect of Taraxacum platycarpum Extract in the Scopolamine-induced Cholinergic Blockade Mouse Model (Scopolamine으로 유도된 콜린성 신경계 차단 동물모델에서 포공영(Taraxacum platycarpum) 추출물의 기억력 개선효과)

  • Kwon, Yubeen;Park, Ho Jae;Shin, Bum Young;Ryu, Jong Hoon
    • Korean Journal of Pharmacognosy
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    • v.48 no.2
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    • pp.119-124
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    • 2017
  • Taraxacum platycarpum H. Dahl. (Compositae) has been used as an anti-inflammatory or anti-cancer agent in the clinic. Although its antidepressant effect has been reported, however, its cognitive function is not investigated until yet. In the present study, we investigated whether the water extract of T. platycarpum (WETP) could improve cognitive function in cholinergic blockade-induced amnesia mouse model using the passive avoidance or Y-maze task. WETP (12.5, 25 or 50 mg/kg) significantly ameliorated the scopolamine-induced cognitive impairment both in the passive avoidance test and the Y-maze test. In addition, WETP significantly inhibited acetylcholinesterase (AChE) activity measured by an ex vivo study using the mouse whole brain. These results suggest that WETP alleviates the cognitive dysfunction caused by the cholinergic blockade, in part, via AChE inhibition, and that it may be a useful for treating cognitive dysfunction.

The Effect of Congruency and Familiarity of Background Music in TV Advertising on the Music's Role as a Retrieval Cue

  • Hwang, Insuk;Kim, Hwa-Kyung
    • Asia Marketing Journal
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    • v.16 no.4
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    • pp.1-18
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    • 2015
  • Assuming that not all background music in advertising function as effective retrieval cues for the advertised messages, this study proposes that we should be able to distinguish the retrieval cue effect of music from the simple ad exposure effect. This study tries to identify which specific characteristics of music are related to the retrieval cue effect. Our experiment focuses on congruency and familiarity of music as key characteristics of music which affect the effectiveness of the music's role as a retrieval cue for the advertised messages. We used four groups of subjects to test the retrieval cue effect of the background music. Each group was exposed to one of the four different types of background music and was again sub-divided into an experimental and a control group (i.e., a total of eight independent sub-groups were included in the experiment.) The first two sub-groups were exposed to the experimental advertisement with the background music of high congruency and high familiarity. After the ad exposure, the background music was provided as a retrieval cue to only one of the two sub-groups. Comparison of the memory performance between the two sub-groups will reveal the net retrieval cue effect of the music of high congruency and high familiarity. Similarly, another two sub-groups watched the same ad but with the background music of high congruency and low familiarity. Also the same ad but with the music of low congruency/ high familiarity was shown to another two sub-groups and that of low congruency and low familiarity music was to another two. Among the two sub-groups with the same music, only one group had the music cue at the memory tasks. One hundred and seventy four undergraduate students at the college of one of authors in Asia participated in the study. Their ages ranged from 18 to 24 with a median of 20. The sample was composed of 51.7 percent male subjects. They were randomly assigned to each of the eight sub-group. The results show that the music highly congruent with the advertised message facilitates the message retrieval, while the low congruency music cue does not. It was also found that the low familiarity music cue improves memory performance only when the music is perceived as congruent with the advertised message. From a theoretical and practical perspective, this study provides boundary conditions for effective retrieval and suggests that the congruent music specifically created for the ad is a more effective retrieval cue than other types of music cues.

Effect of slurries on the dishing of Shallow Trench Isolation structure during CMP process

  • Lee, Hoon;Lim, Dae-Soon;Lee, Sang-Ick
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2002.10b
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    • pp.443-444
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    • 2002
  • The uniformity of field oxide is critical to isolation property of device in STI, so the control of field oxide thickness in STI-CMP becomes enormously important. The loss of field oxide in shallow trench isolation comes mainly from dishing and erosion in STI-CMP. In this paper, the effect of slurries on the dishing was investigated with both blanket and patterned wafers were selected to measure the removal rate, selectivity and dishing amount. Dishing was a strong function of pattern spacing and types of slurries. Dishing was significantly decreased with decreasing pattern spacing for both slurries. Significantly lower dishing with ceria based slurry than with silica based slurry were achieved when narrow pattern spacing were used. Possible dishing mechanism with two different slurries were discussed based on the observed experimental results.

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A Novel Method for Virtual Machine Placement Based on Euclidean Distance

  • Liu, Shukun;Jia, Weijia
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.7
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    • pp.2914-2935
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    • 2016
  • With the increasing popularization of cloud computing, how to reduce physical energy consumption and increase resource utilization while maintaining system performance has become a research hotspot of virtual machine deployment in cloud platform. Although some related researches have been reported to solve this problem, most of them used the traditional heuristic algorithm based on greedy algorithm and only considered effect of single-dimensional resource (CPU or Memory) on energy consumption. With considerations to multi-dimensional resource utilization, this paper analyzed impact of multi-dimensional resources on energy consumption of cloud computation. A multi-dimensional resource constraint that could maintain normal system operation was proposed. Later, a novel virtual machine deployment method (NVMDM) based on improved particle swarm optimization (IPSO) and Euclidean distance was put forward. It deals with problems like how to generate the initial particle swarm through the improved first-fit algorithm based on resource constraint (IFFABRC), how to define measure standard of credibility of individual and global optimal solutions of particles by combining with Bayesian transform, and how to define fitness function of particle swarm according to the multi-dimensional resource constraint relationship. The proposed NVMDM was proved superior to existing heuristic algorithm in developing performances of physical machines. It could improve utilization of CPU, memory, disk and bandwidth effectively and control task execution time of users within the range of resource constraint.

A Study on the Behavior of Combustion Wave Propagation and the Structure of Porous TiNi Body during Self-propagating High-temperature Synthesis Process

  • Kim, Ji-Soon;Gjuntera, Victor E.;Kim, Jin-Chun;Kwon, Young-Soon
    • Journal of Powder Materials
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    • v.17 no.1
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    • pp.29-35
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    • 2010
  • We produced cylindrical porous TiNi bodies by Self-propagating High-temperature Synthesis (SHS) process, varying the heating schedule prior to ignition of a loose preform compact made from (Ti+Ni) powder mixture. To investigate the effect of the heating schedule on the behaviour of combustion wave propagation and the structure of porous TiNi shape-memory alloy (SMA) body, change of temperature in the compact during SHS process was measured as a function of time and used for determining combustion temperature and combustion wave velocity. Microstructure of produced porous TiNi SMA body was observed and the results were discussed with the combustion characteristics. From the results it was concluded that the final average pore size could be controlled either by the combustion wave velocity or by the average temperature of the preform compact prior to ignition.

Over-Sampling Rate for Accurate Evaluation of MLFMM Transfer Function (MLFMM의 Transfer 함수의 정확한 계산을 위한 오버샘플링 비율)

  • Lee, Hyunsoo;Rim, Jae-Won;Koh, Il-Suek
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.10
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    • pp.811-816
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    • 2018
  • When applying the MLFMM algorithm to a large scattering problem, the accuracy of the calculation of the transfer function has a crucial effect on the final simulation results. The numerical accuracy for the double integral on the unit sphere is strongly dependent on the sampling number. With an increasing the sampling points, the overall required memory and running time of the MLFMM simulation also increases. Hence, an optimal over-sampling rate for the number of the sampling points is numerically obtained, which is verified for a real large scattering problem.

The Coupling Effects of Excitatory and Inhibitory Connections Between Chaotic Neurons Having Gaussian-shaped Refractory Function With Hysteresis

  • Park, Changkyu;Lee, Ju-Jang
    • 제어로봇시스템학회:학술대회논문집
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    • 1998.10a
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    • pp.356-361
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    • 1998
  • Neural Networks, modeled succinctly from the real nervous system of a living body, can be categorized into two folds; artificial neural network(ANN) and biological neural network(BNN). While the former has been developed to solve practical problems using function approximation capability, pattern classification) clustering algorithm, etc, the latter has been focused on verifying the information processing capability to which brain research gives an impetus, by mimicking real biological systems. However, BNN suffers Iron severe nonlinearities dealt with. A bridge between two neural networks is chaotic neural network(CNN), which simply delineate the real nor-vous system and comprises almost all the ANN structures by selecting parameters. Main research theme of this area is to develop an explanation tool to clarify the information processing mechanism in biological systems and its extension to engineering applications. The CNN has a Gaussian-shaped refractory function with hysteresis effect and the chaotic responses of it have been observed fur a wide range of parameter space. Through the examination of the coupling effects of excitatory and inhibitory connections, the secrets of information processing and memory structure will appear.

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Effect of chemical in post Ru CMP Cleaning solutions on abrasive particle adhesion and removal (Post Ru CMP Cleaning에서 연마입자의 흡착과 제거에 대한 chemical의 첨가제에 따른 영향)

  • Kim, In-Kwon;Kim, Tae-Gon;Cho, Byung-Gwun;Son, Il-Ryong;Park, Jin-Goo
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.11a
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    • pp.529-529
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    • 2007
  • Ruthenium (Ru) is a white metal and belongs to platinum group which is very stable chemically and has a high work function. It has been widely studied to apply Ru as an electrode material in memory devices and a Cu diffusion barrier metal for Cu interconnection due to good electrical conductivity and adhesion property to Cu layer. To planarize deposited Ru layer, chemical mechanical planarization(CMP) was suggested. However, abrasive particle can induce particle contamination on the Ru layer surface during CMP process. In this study, zeta potentials of Ru and interaction force of alumina particles with Ru substrate were measured as a function of pH. The etch rate and oxidation behavior were measured as a function of chemical concentration of several organic acids and other acidic and alkaline chemicals. PRE (particle removal efficiency) was also evaluated in cleaning chemical.

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The Effect of Cognitive Occupational Therapy in Community Living Elders with Mild Cognitive Impairment and Dementia (지역사회에 거주하는 경증인지장애노인과 치매환자에게 적용한 인지작업치료의 효과)

  • Chong, Bok-Hee
    • Journal of Digital Convergence
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    • v.11 no.3
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    • pp.317-325
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    • 2013
  • The purpose of this study is to evaluate the cognitive functional improvement of cognitive occupational therapy using cognitive function, activities of daily living (ADL) executive function and depression tests in community living elders with mild cognitive impairment (MCI) and dementia. Thirty two elders who diagnosed MCI (n=13) and dementia (n=19) were enrolled in this study. They visited to local elder welfare office and nursing care home from Feb. 2012 to Jun. 2012. They received occupational activity program in terms of physical activity, cognitive function and occupational function of Craft as the manner of a session per week for 8 weeks. The cognitive function, executive function, depression score were improved in both group. Furthermore in MCI participants, cognitive function scores for concentration and memory functions were significant improved more than dementia subjects. Further studies dealing with the development of novel occupational program for cognitive function improvement and its preventive effects were needed.

The Neuroprotective Effect of White Ginseng (Panax ginseng C. A. Meyer) on the Trimethyltin (TMT)-Induced Memory Deficit Rats (Trimethyltin으로 유도된 기억장애 흰쥐에서 백삼의 신경보호효과)

  • Lee, Seung-Eun;Shim, In-Sop;Kim, Geum-Soog;Yim, Sung-Vin;Park, Hyun-Jung;Shim, Hyun-Soo;Ye, Min-Sook;Kim, Seung-Yu
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.6
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    • pp.456-463
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    • 2011
  • The present study examined the effects of Korean white ginseng (WG, Panax ginseng C. A. Meyer) on the learning and memory function and the neural activity in rats with trimethyltin (TMT)-induced memory deficits. The rats were administered with saline or WG (WG 100 or 300 mg/kg, p.o.) daily for 21 days. The cognitive improving efficacy of WG on the amnesic rats, which was induced by TMT, was investigated by assessing the Morris water maze test and by performing immunohistochemistries on choline acetyltransferase (ChAT), acetylcholinesterase (AchE), cAMP responsive element binding protein (CREB) and brain derived neurotrophic factor (BDNF). The rats treated with TMT injection (control group) showed impaired learning and memory of the tasks, but the rats treated with TMT injection and WG administration produced significant improvement of the escape latency to find the platform in the Morris water maze at the 2nd and 4th days compared to that of the control group. In the retention test, the WG 100 and WG 300 groups showed significantly increased crossing number around the platform compared to that of the control group (p < 0.001). Consistently with the behavioral data, result of immunohistochemistry analysis showed that WG 100 mg/kg significantly alleviated the loss of BDNF-ir neurons in the hippocampus compared to that of the control group (p < 0.01). Also, treatment with WG has a trend to be increased the cholinergic neurons in the hippocampal CA1 and CA3 areas as compared to that of the control group. These results suggest that WG may be useful for improving the cognitive function via regulation of neurotrophic activity.