• Clinical and Experimental Pediatrics
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• v.49 no.7
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• pp.790-795
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• 2006

Purpose : This study was performed to compare the therapeutic effects according to duration of medium-dose aspirin(50-60 mg/kg/day) therapy at the acute stage of Kawasaki disease(KD). Methods : Total 87 patients with KD were enrolled in this study. We performed retrospective analysis of clinical characteristics and echocardiographic findings based on medical records. Patient were randomly divided into 2 groups according to the duration of aspirin therapy at the acute stage of KD. Long-term group(LG, n=55) was administered medium-dose aspirin for 2 weeks after diagnosis of KD, and short-term group(SG, n=32) for 48 hours after intravenous immunoglobulin(IVIG) administration. The parameters of therapeutic effects were duration of fever after IVIG administration, incidence of unresponsive patients to single administration of IVIG, and development of transient dilatation or aneurysm of coronary arteries. Results : There was no significant difference in the duration of fever after IVIG between the both group(LG $1.7{\pm}1.1$ days, SG $1.8{\pm}1.1$ days; P=0.588). The incidences of unresponsive patient to the single administration of IVIG were 5.5 percent, 6.3 percent in the each group. Transient dilatation of coronary arteries occurred at 18.2 percent(10/55) in the LG, and 15.6 percent(5/32) in the SG(P=0.761). Prevalence of coronary aneurysm after subacute stage were 7.3 percent(4/55) in the LG, and 9.4 percent(3/32) in the SG(P=0.728). Conclusion : There was no significant difference in the therapeutic effects between long-term(2 weeks) and short-term(48 hours) administration of medium-dose aspirin at the acute stage of KD.

• Weed & Turfgrass Science
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• v.6 no.1
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• pp.61-66
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• 2017

The appropriate level of irrigation for turfgrasses is vital to the performance of the turfgrass as well as conservation of water. Linear gradient irrigation system (LGIS) facilitates long-term study of turf performance under continuous irrigation gradients at extreme ends of the irrigation scale. The objectives of this study were to: a) determine the minimum irrigation requirements and relative drought resistance in three warm season turfgrasses; and b) evaluate the medium to long-term effects of irrigation levels on turf persistence, weed invasion, and susceptibility to diseases. Results suggest that grasses differed in drought resistance and persistence under variable irrigation regimes. Irrigation (Ep) required for consistent acceptable turf quality for respective grasses was Cynodon dactylon x C. transvaalensis (61%), Zoysia matrella L. Merr (73%), and Stenotaphrum secundatum 'Palmetto' (86%). Brown patch infection was most prevalent in Stenotaphrum secundatum 'Palmetto' at 12 and 125% Ep irrigation. Cynodon dactylon x C. transvaalensis and Zoysia matrella L. Merr were better able to adapt to the various irrigation regimes, and this ability allowed these species to resist drought, and maintain turf coverage which in turn, kept weeds and the occurrence of diseases at bay. Ranking these grasses for their drought tolerance abilities showed that Cynodon dactylon x C. transvaalensis had the most outstanding resistance against drought, followed by Zoysia matrella L. Merr, and lastly, Stenotaphrum secundatum 'Palmetto'. Despite having the highest irrigation requirement, Stenotaphrum secundatum 'Palmetto' was still not able to maintain persistence at high irrigation regimes. Likewise, this grass also lost turf coverage at low irrigation levels.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.1
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• pp.45.2-46
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• 2017

3C 84 (NGC 1275) is one of the most famous radio galaxies and a lot of VLBI observations have been conducted to date because of its brightness and proximity (z = 0.0176; 1 mas = 0.36 pc). The source is entering a significantly active phase with long-term increase in radio flux at cm wavelengths since 2005, and the increased activity at very-high-energy (VHE) gamma rays. In order to study properties of sub-pc-scale structure and the circumnuclear environment in 3C 84, we have conducted multi-epoch VLBI observations with the Korean VLBI Network (KVN) at 86 and 129 GHz, and monthly monitoring by the KVN and VERA Array (KaVA) at 43 GHz from 2015 August. Following the report in the previous KAS meeting (cf. 2016 KAS Autumn Annual Meeting, [구 GC-10]), we present further results mainly on the basis of twelve-epoch observations with KaVA at 43 GHz. Through the monthly monitoring with KaVA, we found that peak intensity of the pc-scale southern lobe (C3) was increased from $2.60\;Jy\;beam^{-1}$ in 2015 October to $9.80\;Jy\;beam^{-1}$ in 2016 June, corresponding to a flux increase of 3.7 times in eight months. We also detected change in direction of motion of C3 from transversal to outward with respect to C1, concurrently with the beginning of its flux increase in 2015 October. We consider that these phenomena are due to interaction of C3 with the ambient medium, and are related to the gamma-ray flare which has been detected with VHE gamma-ray telescopes such as MAGIC and VERITAS.

• Korean Journal of Organic Agriculture
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• v.26 no.4
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• pp.585-597
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• 2018

The purpose of this study is to analyze the cases of Asan-si and Hongseong-gun in Chungcheongnam-do to derive the direction of development of the school meal support center and improvement of the school meal policy in connection with local food. We conducted a survey on the importance and performance of school meal support policy and local food supply policy for nutritionists in two areas. In addition, we identified the issues to be improved intensively and the issues to be continuously managed over the medium to long term, and suggested directions for improvement using IPA. As a result of the importance-performance analysis of school meal support policy and local food supply policy, both Asan-si and Hongseong-gun. focused on improving the price and quality of local food.

• Journal of Korea Multimedia Society
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• v.22 no.8
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• pp.897-912
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• 2019

The growth of domestic fashion industry market went sluggish affected by long-term slow growth and shrinking consumer sentiment since 2012, and the entire market has shown a slight growth since 2017. Yet only some conglomerates or global businesses experience this growth. Small and medium-sized fashion companies or rising fashion designers in South Korea, face real limitations and problems poor capital, lack of professional workforce, experience, information and educational opportunity as well as difficulty of acquiring distribution network, which lead to further polarization between conglomerates and small businesses. Thus, this study proposed mobile virtual viewer system-based collaborative application prototype capable of overcoming limitations and problems drawn by analyzing business environment of domestic brands launched by rising fashion designers. Especially, through applied template-based 3D virtual fashion design technology and performing the entire process in the virtual reality beyond spatial and temporal restraints, it is assumed that more effective and efficient outcomes can be obtained compared to the previous method.

• Journal of Pharmaceutical Investigation
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• v.38 no.3
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• pp.157-162
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• 2008

The aim of the study was to formulate the stable amlodipine maleate tablet by selecting and combining of suitable ingredients. Amlodipine tablets were designed by using different manufacturing methods or formulations. Dissolution rate at 30 min of newly formulated tablets was over 98% in 0.1 M HCl medium. After 4 months storage under accelerated condition, the changes of appearance, loss on drying, content and total impurity were investigated. For long-term stability tests, two formulations of K017 (direct compressed tablets consisting of microcrystalline cellulose and pregelatinized starch) and K018 (wet granulated tablets by OpadryAMB) were stored under $25^{\circ}C$, 60% RH for 24 months. Under the accelerated condition, moisture content in K017 formulation was increased as 5.96% for 4 months, while other formulations with anhydrous monobasic phosphoric potassium or by wet granulation showed higher increase in moisture content compared to K017. In addition, K017 formulation showed a low decrease in contents and total relative substance as 0.8% and 0.7%, respectively. Similar stability of amlodipine in K017 was obtained under the long-term stability test. These results indicate that the K017 combined with microcrystalline cellulose and pregelatinized starch as ingredients is very stable formulation to protect active substance from moisture contact and sustain stability. Therefore, suitable combination of ingredients such as microcrystalline cellulose and pregelatinized starch could attribute to enhance the stability of moisture-labile drug such as amlodipine maleate.

• East Asian Economic Review
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• v.17 no.1
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• pp.27-53
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• 2013

In this paper, we look at the relationship between international trade and the rule of law, using the World Justice Project Rule of Law Index, which include index figures on human rights, limits on government powers, transparency and regulatory efficiency. Based on regression analyses using the rule of law index figures and international trade figures (merchandise trade, service trade, exports and imports as percentage of GDP,) international trade and basic human rights seem to have little relationship; but trade has a close positive relationship with strong order and security. Somewhat surprisingly, regulatory transparency and effective implementation seems to have little or no effect on international trade and vice versa. International trade shows a clear positive relationship with the country's criminal justice system, but the relationship with the civil justice system is not as clear as such. For regulatory implementation and civil justice, services trade positively affect these institutions, but these institutions in turn affect exports more strongly than services trade. Finally, the effect of trade on rule of law is stronger on a medium to long term (10-20 year) time horizon.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.30 no.3
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• pp.71-81
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• 2007

Government-driven informatization support projects for small and medium companies turn into collaborative information technology alliances between mother companies and their suppliers. These collaboration efforts are driven by a mother company that can influence and support its suppliers. A mother company establishes a proprietary evaluation system for suppliers' informatization level and enforces the suppliers to use their ERP (Enterprise Resource Planning) systems above a certain level. This paper presents a Samsung Electronics case to find determinant factors for ERP system usage level. This case study aims at providing long-term strategies for the collaboration project and helping the suppliers effectively pursue their informatization projects. Furthermore, the case study will reveal issues and tasks for the mother companies to accomplish sustainable success for their suppliers' informatization.

• Geomechanics and Engineering
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• v.32 no.4
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• pp.397-409
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• 2023

This study examines two traditional approaches (non-linear elastic and elasto-plastic) in association with 2D and 3D FEM analyses of a box-section pile embedded in sand. A particular emphasis is placed on stress singularities concerning both reentrant corners of the pile section and the resulting tension zones. From the experience gained in this study, non-linear elastic soil models are less restrictive when one considers stress singularities and their possible effects on convergence of the solution. At least for monotonic loading, when compared with field tests, non-linear elastic models yield better results than the plasticity ones. On the other hand, although elasto-plastic models are not limited to monotonic loading, they are much more sensitive to stress singularities. For this reason, a spherical elastic region is necessary at the pile tip to ensure convergence. Without this region, one must artificially impose an apparent cohesion to limit the tension stresses within a sand medium.

• The Korean Journal of Pharmacology
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• v.29 no.2
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• pp.237-244
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• 1993

The effect of nicotine on the secretion of $[Met^{5}]-enkephalin$ (ME) in addition to proenkephalin A (proENK) mRNA levels and effects of indomethacin, nordihydroguaiaretic acid (NDGA), and captopril on nicotine-induced responses were studied in bovine adrenal medullary chromaffrin (BAMC) cells. Long-term exposure of BAMC cells to nicotine at a concentration of $10{\mu}M$ significantly increased proENK mRNA level and the secretion of ME into the medium. Treatment of BAMC cells with NDGA (a lipoxygenase inhibitor, $10{\mu}M$), indomethacin (a cycloooxygenase inhibitor) or captopril (an angiotensin converting enzyme inhibitor) alone did not affect ME secretion and proENK mRNA levels. The pretreatment of BAMC cells with NDGA inhibited the increased ME secretion and proENK mRNA level induced by nicotine. However, indomethacin and captopril did not affect nicotine-induced responses. Our results indicate that neuronal regulations of ME secretion and proENK mRNA level induced by nicotine in BAMC cells are in part mediated by a lipoxygenase-but not cyclooxygenase-and endogenous renin-angiotensin pathway.