• Title/Summary/Keyword: medicinal herbs

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Analysis of Main Single Medicinal Herbs for Anti-Obesity Miyoung Song, Hojun Kim Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dongguk University Received: November (비만에 작용하는 주요 본초의 항비만 효과 분석)

  • Song, Miyoung;Kim, Hojun
    • Journal of Korean Medicine for Obesity Research
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    • v.13 no.2
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    • pp.51-57
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    • 2013
  • Objectives: This study was conducted to analyze anti-obesity effects of the main single medicinal herbs which have effects on obesity or metabolic syndrome. Methods: We selected the 8 main single medicinal herbs, and then 3 databases were searched using search words "obesity", and "each scientific name of selected 8 main herbs". Results and Conclusions: Only Ephedra sinica and Panax ginseng were analyzed through 3 methods, in vitro, animal studies and randomized controlled trial (RCT)s, Ephedra sinica was shown weight loss effects in RCTs, but Panax ginseng couldn't. Other 6 selected medicinal herbs were not verified in RCTs, all had anti-obesity effects in high fat fed mice (or rats) and the others except for Radix notoginseng and Radix puerariae had inhibitory effects on lipid accumulation in 3T3-L1 cells.

Neuroprotective Effects of Medicinal Herbs in the Transient Focal Ischemia

  • Oh, Jin-Kyung;Jung, Ji-Wook;Ahn, Nam-Yoon;Oh, Hye-Rim;Ryu, Jong-Hoon
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2003.11a
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    • pp.64-64
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    • 2003
  • It is thought that highly reactive oxygen radicals generated at the ischemia-reperfusion in case of strokes play an important role in damaging the brain. We examined the neuroprotective effects from the several medicinal herbs in the transient ischemic rat model and compared their effects with the free radical scavenging activities. Transient ischemia was induced by intraluminal occusion of the right middle cerebral artety for 120 min and reperfusion was continued for 22 h in rats. The free radical scavenging properties of medicinal herbs were examined in vitro by determination of the interaction with the 1,l-diphenyl-2-picrylhydrazyl (DPPH) stable free radical. Aqueous extracts of 11 medicinal herbs (200 mg/kg) were orally administered, promptly prior to reperfusion and 2 h after reperfusion. Total infarction volume in the ipsilateral hemisphere of ischemia reperfusion rats was significantly lowered by the treatment of 7 medicinal herbs (Sophora flavescens, Lycopus lucidus, Sanguisorba officinalis, Caesalpinia sappan, Albizia julibrissin, Rubia akane, Psoralea corylifolia, Prunella vulgaris). However, all of these medicinal herbs did not show antioxidative activities. These results suggest that neuroprotective effects of several drugs are not always correlated with their antioxidative properties.

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Naturally Occurring of Sulfur Dioxide in Medicinal Herbs(Crude Drug Materials) and Its Origin (생약재중 천연유래 이산화황 함유량 및 그 출처)

  • Kang, Kil-Jin;Oh, Geum-Soon;Kim, Hyung-Il;Choi, Yong-Hoon;Kim, Yong-Jae;Chung, Youn-Chan
    • Korean Journal of Food Science and Technology
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    • v.33 no.5
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    • pp.514-520
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    • 2001
  • Naturally occurring sulfur dioxide in medicinal herbs(crude drug materials) and its origin was investigated. Sulfur dioxide content in 28 kinds (101 samples) of medicinal herbs was studied by two different methods, Monnier-Williams and acid-distillation ion chromatography. Generally, less than 5 ppm of sulfur dioxide was found from the tested herbs. In some herbs, Monnier-Williams method showed higher level of sulfur dioxide than acid-distillation ion chromatography probably due to the presence of volatile organic acid presence in herbs. Naturally occurring sulfur dioxide measured in medicinal herbs may be derived from sulfur compounds of medicinal herbs.

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Tasks for the Separation of Prescribing and Dispensing medicinal herbs in Traditional Korean Medicine (한의약분업과 관련된 여러 가지 문제)

  • Lee, Hai-Woong;Kim, Hoon;Kim, Gyeong-Cheol;Kim, Jong-Hwan;Shin, Woo-Jin;Park, Dong-Il;Hwang, Won-Duk
    • Journal of Korean Medical classics
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    • v.23 no.1
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    • pp.133-142
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    • 2010
  • Preconditions for the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine are classification of medicinal herbs for general public and special medical uses, establishment of national medicinal herb distribution company of governmental base, restriction in purchase of medicinal herbs for special medical use, partnership between doctors and pharmacists of Traditional Korean Medicine, and coverage of herbal medicine-based medication in national health insurance, etc. The number of Traditional Korean Medicine Pharmacists which was born during 'the herbal medicine conflict' initiated in 1993, goes over 1,000 and will increase by 120 annually. The number of Traditional Korean Medical Doctors is over 17,000 and increases by 850 annually. So in order to engage partnership between two groups, the government have to arrange the number of outputs of each group. Standardization and classification of diagnosis and diseases in Traditional Korean Medicine is a matter of course in the separation of prescribing and dispensing medicinal herbs. Related societies and academies need to do researches with governmental fund first. After these works, we can launch a task force team for implementation of process for the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine properly. Entering the national health insurance system for full coverage of Korean Medicine care service will be essential for the patients. Implementation the separation of prescribing and dispensing medicinal herbs in Traditional Korean Medicine would be the core of health insurance coverage for medication.

Analysis of Sulfur Dioxide Residue in Commercial Medicinal Herbs in Seoul (2009) (2009년 서울지역 유통 한약재의 이산화황 잔류실태 분석)

  • Yoon, Yong-Tae;Lee, Sung-Deuk;Park, Ae-Sook;Shin, Young;Kim, Hwa-Soon;Kim, Yoo-Kyung;Choi, Byung-Hyun
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.5
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    • pp.345-360
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    • 2010
  • This study was conducted to investigate the content of sulfur dioxide residues in medicinal herbs in Seoul in 2009. Sulfur dioxide in the samples were determined by Monnier-Williams's modified method. A total of 1,821 samples of 205 different types of herbs were collected from Kyung-Dong Herb markets and Oriental medicine hospitals in Seoul. Of these samples, 642 samples were domestic, and 1,179 samples were imported. Of the 1,821 samples, 61 (3.3%, 31 types) failed to meet the regulations for sulfur dioxide residues of KFDA in medicinal herbs. Among these 61 unsuitable samples, 17 (7 types) were domestic, and 44 samples (26 types) were imported. The content of sulfur dioxide in the domestic medicinal herbs ranged from 0 to 809 mg/kg, while those in imported medicinal herbs ranged from 0 to 4,481 mg/kg. Approximately 84.6% of the samples contained less than 10 mg/kg of sulfur dioxide and about 10.0% of samples contained more than 30 mg/kg of sulfur dioxide.

Korean Medicinal Herb Extracts Inhibit Melanin Formation in Clone M-3 Mouse Melanocyte Cell Lines

  • Park, Kap-Joo;Choo, Dong-Wan;Lee, Hyung-Hoan
    • Korean Journal of Environmental Biology
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    • v.22 no.2
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    • pp.336-340
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    • 2004
  • In order to search for anti -melanin formation agents from Korean medicinal herbs, we selected 21 Korean medicinal herbs, based on a review of Korean traditional medicine books and the recommendations of Korean traditional medical doctors. We tested for inhibition effect of melanin pigmentation of Clone M-3 mouse melanocyte cell lines when we treated the extracts of 21 medicinal herbs in the mouse melanocyte cell lines, respectively. Among 21 medicinal herb extracts, 5 extracts showed a inhibition effect of melanin formation. The sample Phaseolus radiatus L, Cordyceps militaris, Pinellia ternata, Phellinus linteus and Citrus junos Tanaka showed a significantly little formation of melanin pigments compared with control groups. Especially extract of Citrus junos Tanaka was more potent than the others. These results suggest that extract of Korean Citrus junos may represents an excellent candidate for inhibition of melanin pigmentation at in vitro level.

Study on local medicinal herbs in Bonchojeonghwa Chapter of Grass ("본초정화(本草精華)" 초부(草部) 향약명(鄕藥名)에 관(關)한 연구(硏究))

  • Lee, Deok-Ho;Eom, Dong-Myung;Kim, Hong-Kyoon
    • Korean Journal of Oriental Medicine
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    • v.11 no.1
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    • pp.1-18
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    • 2005
  • As a result of study on the names of local medicinal herbs which described in Chobu (Chapter of Grass) of Korean medical book Bonchojeonghwa, we came to the following conclusions. 1) Compared with the existing domestic medical books' local medicinal herb names, those of Donguibogam had the closest relationship with Bonchojeonghwa. Out of local medicinal herb names described in Chobu of Bonchojeonghwa, a third is only shown in Bonchojeonghwa, and another third is same as those in Donguibogam. 2) The notation of local medicinal herb names in Bonchojeonghwa is not so consistent as Donguibogam. In Bonchojeonghwa, we can see many examples of inconsistent notations over the same thing. Moreover, there are some examples, which are suspected to be an expression of dialect. 3) In spite of close similarity between the names of local medicinal herbs in Bonchojeonghwa and Donguibogam, the author of Bonchojeonghwa doesn't seem to directly refer to or quote Donguibogam, because it doesn’t make sense that the author of Bonchojeonghwa intentionally referred to regular, consistent Donguibogam in irregular, inconsistent way. 4) In spite of very low possibility of direct reference or quotation among Bonchojeonghwa, Donguibogam and Bangyakhappyon, there are many examples of common format in its notation way on local medicinal herbs, which cannot be explained only as coincidence. And it tells us that there must be another publication which had been referred to or quoted by the said three medical books. 5) From the fact that there are a lot of examples of local medicinal herb names which doesn't show palatalization, or labialization, the names of local medicinal herbs described in Bonchojeonghwa must be the expression around 17th century.

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HF-IFF: Applying TF-IDF to Measure Symptom-Medicinal Herb Relevancy and Visualize Medicinal Herb Characteristics - Studying Formulations in Cheongkangeuigam - (HF-IFF: TF-IDF를 응용한 병증-본초 연관성(relevancy) 측정과 본초 특성의 시각화 -청강의감 방제를 대상으로-)

  • Oh, Junho
    • The Korea Journal of Herbology
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    • v.30 no.3
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    • pp.63-68
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    • 2015
  • Objectives : We applied the term weighting method used in the field of data search to quantify relevancy between symptoms and medicinal herbs, and, based on this, we aim to introduce a method of visualizing the characteristics of medicinal herbs. Methods : We proposed HF-IFF, an adaptation of TF-IDF, which is a term weighting measurement method adapted in the field of data search. Using this method, we deduced relevancy between symptoms and medicinal herbs In Cheongkangeuigam that was published in 1984 by organizing the medical theory of Cheongkang, Kim Younghoon, and visualized this as a graph in order to compare the characteristics of medicinal herbs used for different symptoms. Results : HF-IFF is the product of HF and IFF, where HF is the frequency of the relevant medicinal herb for a set of symptoms, and IFF is the inverse of the number of formulations (FF) containing that herb. A total of 251 types of medicinal herb are used in Cheongkangeuigam, and 1538 formulations are classified according to 67 types of symptom. The overall mean for HF-IFF was 0.491, with a maximum of 4.566 and a minimum of 0.013. Conclusions : In spite of several limitations, we were able to use HF-IFF to measure relevancy between symptoms and medicinal herbs, with formulations as an intermediate. We were able to use the quantified results to visually express the characteristics of the herbs used for symptoms by bubble chart and word-cloud from HF-IFF.