• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.4109-4114
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• 2015

Background: Full-field digital mammography (FFDM) with dense breasts has a high rate of missed diagnosis, and digital breast tomosynthesis (DBT) could reduce organization overlapping and provide more reliable images for BI-RADS classification. This study aims to explore application of COMBO (FFDM+DBT) for effect and significance of BI-RADS classification of breast cancer. Materials and Methods: In this study, we selected 832 patients who had been treated from May 2013 to November 2013. Classify FFDM and COMBO examination according to BI-RADS separately and compare the differences for glands in the image of the same patient in judgment, mass characteristics display and indirect signs. Employ Paired Wilcoxon rank sum test was used in 79 breast cancer patients to find differences between two examine methods. Results: The results indicated that COMBO pattern is able to observe more details in distribution of glands when estimating content. Paired Wilcoxon rank sum test showed that overall classification level of COMBO is higher significantly compared to FFDM to BI-RADS diagnosis and classification of breast (P<0.05). The area under FFDM ROC curve is 0.805, while that is 0.941 in COMBO pattern. COMBO shows relation of mass with the surrounding tissues, the calcification in the mass, and multiple foci clearly in breast cancer tissues. The optimal sensitivity of cut-off value in COMBO pattern is 82.9%, which is higher than that in FFDM (60%). They share the same specificity which is both 93.2%. Conclusions: Digital Breast Tomosynthesis (DBT) could be used for the BI-RADS classification in breast cancer in clinical.

• Journal of Korea Multimedia Society
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• 제25권3호
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• pp.451-460
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• 2022

Recently, several deep learning studies have been reported to automatically identify the location of diagnostic devices using endoscopic data. In previous studies, there was no design to determine whether the configuration of the dataset resulted in differences in the accuracy in which artificial intelligence models perform image classification. Studies that are based on large amounts of data are likely to have different results depending on the composition of the dataset or its proportion. In this study, we intended to determine the existence and extent of accuracy according to the composition of the dataset by compiling it into three main types using larynx, esophagus, gastroscopy, and laryngeal endoscopy images.

• Journal of Physiology & Pathology in Korean Medicine
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• 제23권1호
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• pp.97-103
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• 2009

The status and the property of a tongue are the important indicators to diagnose one's health like physiological and clinicopathological changes of inner organs. However, the tongue diagnosis is affected by examination circumstances like a light source, patient's posture, and doctor's condition. To develop an automatic tongue diagnosis system for an objective and standardized diagnosis, classifying tongue coating is inevitable but difficult since the features like color and texture of the tongue coatings and substance have little difference, especially in the neighborhood on the tongue surface. The proposed method has two procedures; the first is to acquire the color table to classify tongue coatings and substance by automatically separating coating regions marked by oriental medical doctors, decomposing the color components of the region into hue, saturation and brightness and obtaining the 2nd order discriminant with statistical data of hue and saturation corresponding to each kind of tongue coatings, and the other is to apply the tongue region in an input image to the color table, resulting in separating the regions of tongue coatings and classifying them automatically. As a result, kinds of tongue coatings and substance were segmented from a face image corresponding to regions marked by oriental medical doctors and the color table for classification took hue and saturation values as inputs and produced the classification of the values into white coating, yellow coating and substance in a digital tongue diagnosis system. The coating regions classified by the proposed method were almost the same to the marked regions. The exactness of classification was 83%, which is the degree of correspondence between what Oriental medical doctors diagnosed and what the proposed method classified. Since the classified regions provide effective information, the proposed method can be used to make an objective and standardized diagnosis and applied to an ubiquitous healthcare system. Therefore, the method will be able to be widely used in Oriental medicine.

• Progress in Medical Physics
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• 제30권2호
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• pp.39-48
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• 2019

Deep learning has been applied to various medical data. In particular, current deep learning models exhibit remarkable performance at specific tasks, sometimes offering higher accuracy than that of experts for discriminating specific diseases from medical images. The current status of deep learning applications to molecular imaging can be divided into a few subtypes in terms of their purposes: differential diagnostic classification, enhancement of image acquisition, and image-based quantification. As functional and pathophysiologic information is key to molecular imaging, this review will emphasize the need for accurate biomarker acquisition by deep learning in molecular imaging. Furthermore, this review addresses practical issues that include clinical validation, data distribution, labeling issues, and harmonization to achieve clinically feasible deep learning models. Eventually, deep learning will enhance the role of theranostics, which aims at precision targeting of pathophysiology by maximizing molecular imaging functional information.

• Proceedings of the KOSOMBE Conference
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.546-549
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• 1997

3D medical image reconstruction techniques are useful to figure out complex 3D structure from the set of 2D sections but their implementations are difficult due to processor's limitation and their computational complexity. In this paper, we propose a new speed optimization technique or accelerating the volume rendering algorithm. In addition, the whole procedure or reconstructing the medical images are constructed by using Visual C++ 5.0 under PC environment. They include classification, shading and ray-casting.

• Proceedings of the KOSOMBE Conference
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.133-136
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• 1997

The human chromosome analysis is widely used to diagnose genetic disease and various congenital anomalies. Many researches on automated chromosome karyotype analysis has been carried out, some of which produced commercial systems. However, there still remains much room or improving the accuracy of chromosome classification. In this paper, We propose an optimal pattern classifier by neural network to improve the accuracy of chromosome classification. The proposed pattern classifier was built up of multi-step multi-layer neural network(MMANN). We reconstructed chromosome image to improve the chromosome classification accuracy and extracted three morphological features parameters such as centromeric index(C.I.), relative length ratio(R.L.), and relative area ratio(R.A.). This Parameters employed as input in neural network by preprocessing twenty human chromosome images. The experiment results show that the chromosome classification error is reduced much more than that of the other classification methods.

• The KIPS Transactions:PartD
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• 제10D권1호
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• pp.109-116
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• 2003

In this paper, a CORBA-based collaborative medical image analysis and visualization system, which provides high accessibility and usability of the system for the users on distributed environment is introduced. The system allows us to manage datasets and manipulates medical images such as segmentation and volume visualization of computed geometry from biomedical images in distributed environments. Using Bayesian classification technique and an active contour model the system provides classification results of medical images or boundary information of specific tissue. Based on such information, the system can create real time 3D volume model from medical imagery. Moreover, the developed system supports collaborative work among multiple users using broadcasting and synchronization mechanisms. Since the system is developed using Java and CORBA, which provide distributed programming, the remote clients can access server objects via method invocation, without knowing where the distributed objects reside or what operating system it executes on.

• Journal of Biomedical Engineering Research
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• 제17권4호
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• pp.545-552
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• 1996

Researches on chromosome are very significant in cytogenetics since a gene of the chromosome controls revelation of the inheritance plasma The human chromosome analysis is widely used to diagnose genetic disease and various congenital anomalies. Many researches on automated chromosome karyotype analysis has been carried out, some of which produced commercial systems. However, there still remains much room for improving the accuracy of chromosome classification. In this paper, we propose an algorithm for reconstruction of the chromosDme image to improve the chromosome classification accuracy. Morphological feature parameters are extracted from the reconstructed chromosome images. The reconstruction method from chromosome image is the 32 direction line algorithm. We extract three morphological feature parameters, centromeric index(C.I.), relative length ratio(R.L.), and relative area ratio(R.A.), by preprocessing ten human chromosDme images. The experimental results show that proposed algorithm is better than that of other researchers'comparing by feature parameter errors.

• Journal of Biomedical Engineering Research
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• 제19권2호
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• pp.189-198
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• 1998

3D medical image reconstruction techniques are useful to figure out complex 3D structures from the set of 2D sections. In the paper, 3D medical image reconstruction system is constructed under PC environment and programmed based on modular programming by using Visual C++ 4.2. The whole procedures are composed of data preparation, gradient estimation, classification, shading, transformation and ray-casting & compositing. Three speed optimization techniques are used for accelerating 3D medical image reconstruction technique. One is to reduce the rays when cast rays to reconstruct 3D medical image, another is to reduce the voxels to be calculated and the other is to apply early ray termination. To implement 3D medical image reconstruction system based on PC, speed optimization techniques are experimented and applied.

• Journal of Korea Multimedia Society
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• 제21권2호
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• pp.130-137
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• 2018

Recently, human life is getting longer due to change of living environment and development of medical technology, and silver medical technology has been in the limelight. Geriatric skin disease is difficult to detect early, and when it is missed, it becomes a malignant disease and is difficult to treatment. Melanoma is one of the most common diseases of geriatric skin disease and initially has a similar modality with the nevus. In order to overcome this problem, we attempted to perform a feature analysis in order to attempt automatic detection of melanoma-like lesions. In this paper, one is first order analysis using information of pixels in radiomic feature. The other is a gray-level co-occurrence matrix and a gray level run length matrix, which are feature extraction methods for converting image information into a matrix. The features were extracted through these analyses. And classification is implemented by SVM.