• Archives of Pharmacal Research
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• 제10권2호
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• pp.80-87
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• 1987

To get a better insight into the exxistence and the role of a Na-Ca exchange mechanism in smooth muscle, the effect of Na substitution with sucrose on tension development, cellular Ca uptake and $^{45}Ca$ efflux was investigated using isolated cat ileal longitudinal muscle strips. Experimental results were summarized as follows;1) Exposure of the cat ileal longitudinal muscle to Na-free solution induced a contraction, and the magnitude of the contraction increased after incubation of the muscle strips with ouabain ($2{\times10^{-}5}$M) for 1hr. 2) Cellular Ca uptake in Na-free solution increased with an increase in Na content of the Na-loading media, and a linear relationship existed between tissue Na content and cellular Ca uptake for 10 min 3) After tissues were equilibrated in PSS containing $^{45}Ca$ for 2hr, cellular Ca uptake decreased with rising the external Na concentration. 4)Removal of medium Na or inhibition of the Na-K pump decreased the rate of $^{45}Ca$ efflux. These results strongly suggested that Na substitution increases cellular Ca uptake and decreases the rate of $^{45}Ca$ efflux via a Na-Ca exchange mechanism.

• Journal of Microbiology
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• 제34권2호
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• pp.179-183
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• 1996

Streptoccus Pneumoniae (pneumococcus), the most common cause of bacterial pneumonia, has an ample polysaccharide (PS) capsule that is highly antigenic and is the source of PS vaccine. This investigation was undertaken to optimize the culture conditions for the production of capsulard PS by type 1 pneumococcus. Among several culture media, brain heart infusion (BHI) and Casitone based media were found to support luxuriant growth of pneumococcus type 1 at the same level. Because BHI medium is rather expensive and more complex than the Casitone based media, the Casitone based media was uwed to study optimization of the culture condition. The phase of growth which accomodated maximum PS production was logarithmic phase. Concentrations of glucose greater than 0.2% did not ehnahce growth or PS production. Substitution of netrogen sources with other resources or supplementation of various concentrations of metal ion (with the exception of calcium ion) had adverse affects on growth and PS production. On the other hand, low level aeration was beneficial for increased PS production. Addition of 3 mg/1 concentration of methionine, phenylalanine, and threonine were found to enhance growth and PS production. The synerigistic effect of all the favorable conditions observed in pneumococcal growth assays provided a two-fold cummulative increase in capsular PS production.

• 미생물학회지
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• 제31권3호
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• pp.203-207
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• 1993

Five different secretion vectors were constructed by varying the signal sequences and .alpha.-antitrypsin (.alpha.1-AT) a numan secretory protein, was produced from yeast cells. The signal sequences used are those of acid phosphatase (PH05) and .alpha.-factor (M f.alphal1) of Saccharomyces cerevisiae, glucoamylase (STA1) of Saccharomyces diastaticus, and human .alpha.1-AT. Four vectors directed the efficient secretion of .alpha.1-AT ito the culture media. The secretion vector carrying the glucoamylase signal sequence (pGAT11) showed the highest efficiency of secretion. About 70% of .alpha.1-AT produce dwere secreted into the media. The endo H treatment of partially purified .alpha.1-AT indicates that the secreted .alpha.1-AT appeared to be glycosylated. This glycosylation pattern was altered when amino acid substitution mutations were introduced at the three glycosylation sites of .alpha.-AT.

• Nuclear Engineering and Technology
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• 제50권5호
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• pp.639-647
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• 2018

In this study, the effects of selecting water/silver nanofluid as both a coolant and a reactivity controller during the first operating cycle of a light water nuclear reactor are investigated. To achieve this, coupled neutronic-thermo-hydraulic analysis is employed to simulate the reactor core. A detailed VVER1000/446 reactor core is modeled in monte carlo code (MCNP), and the model is verified using the porous media approach. Results show that the maximum required level of silver nanoparticles is 1.3 Vol.% at the beginning of the cycle; this value drops to zero at the end of cycle. Due to substitution of water/boric acid with water/Ag nanofluid, reactor operation time at maximum power extends to 357.3 days, and the energy generation increases by about 27.3%. The higher negative coolant temperature coefficient of reactivity in the presence of nanofluid in comparison with the water/boric acid indicates that the reactor is inherently safer. Considering the safety margins in the presence of the nanofluid, minimum departure from nucleate boiling ratio is calculated to be 2.16 (recommendation is 1.75).

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XII)
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• pp.249-252
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• 2003

Maximal production of heteropolysaccharide-7(PS-7) with a batch culture for 48 hr was $10.0\;g/{\ell}$ and its conversion rate from 2% (w/v) glucose to PS-7 was 50%. After substitution of media, production of PS-7 continued and reached its maximal production. The highest productivity occurred when the fresh medium, which contained all ingredients, for the production of PS-7 was substituted. Higher production of PS-7 was maintained at a dilution rate of 0.0125, which was established as the optimal dilution rate for the production of PS-7 by B. indica HS-2001.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2017년도 하계학술대회
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• pp.91-94
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• 2017

본 연구에서는 Component-Substitution (CS)기반 영상 융합 방법 중 가장 빠른 처리 속도를 보이는 IHS 기법의 분광 왜곡 현상을 해결하기 위하여 히스토그램을 통해 분광 왜곡 현상을 분석하고 평균 필터링을 통해 분광 왜곡 현상을 해결한다. 제안하는 방법의 성능 평가를 위하여 아리랑 3 호로 촬영한 서울 지역 위성 영상에 IHS 방법과 제안하는 방법을 적용하여 주관적으로 비교하고 객관적으로는 Q4, SAM, ERGAS 의 지표를 사용하여 비교한다. 주관적 비교 결과 제안하는 방법이 분광 왜곡을 감소시킴을 보이며, 객관적 비교 결과 IHS 기법 대비 향상된 Q4, SAM, ERGAS 을 보인다.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2003년도 춘계학술발표대회 논문집
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• pp.192-195
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• 2003

Digital art brought about first in 19s6s by Laposky Ben and became a area of new art. Also, digital art gives new possibility to systematize concept and actions in whole art and to invent some media which can carry the sense experience with space. However, reason that has often cynical meaning is appearing in preconception which technology falls off humanity. Because of digital technology, space production can become dreary, so it is necessary to sensuous production that connects digital with space which contains meaning of interior space. The purpose of this study is to find out spare which can be communicated from viewpoint of interaction through spatial substitution and characteristics of various expression production which have been involved newly in digital art area.

• 물과 미래
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• 제24권1호
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• pp.109-117
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• 1991

포화-비포화 영역에서 transient흐름 해석을 위해 유체의 연속방정식과 Darcy 법칙으로부터 다공질 매체에서의 흐름 지배방정식을 유도하였다. 수치해는 가중잔차원리에 입각한 Galerkin 유한요소법으로 구하며, 시간도함수항에는 유한차분법을 적용하였다. 해석에서는 실제 자연상태에서 발생되는 부정호우자료를 이용하고 이때의 지표하 흐름 해석에 필요한 강우 주상도는 제 손실성분을 고려한 초과우량 추정모형으로부터 얻었다. 비포화 토양에서의 흐름을 고려하기 위해 투수계수, 압력수두 및 체적함수비의 상호 함수관계를 이용하였다. 모형은 대칭인 2차원으로서 비등방성, 이질 토층으로 구성하였다.

• Korean Journal of Hydrosciences
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• 제2권
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• pp.13-24
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• 1991

The governing partial differential equation of flow in porous media is developed on the bases of the continuity equation of fluid for transient flow through a saturated-unsaturated zone, and substitution of Dercy's law. The numerical solution is obtained by the Galerkin finite element method based on the principle of weighted residuals. The analysis is carried out by using the unsteady storm data observed and the functional relationships between the hydraulic conductivities, capillary pressure heads, and volumetric water contents under saturated-unsaturated conditions. As the results the hydraulic conductivities, rates of change of storage and initial moisture conditions are significantly influened on the responses of subsurface flow on a hillslope.

• 한국유기농업학회지
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• 제30권1호
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• pp.37-50
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• 2022

This study analyzes the impact of Import beer demand on Anti-Japanese sentiment. Recently anti-Japanese sentiment heightened by the media was found to be drastically reducing the consumption of Japanese beer in the domestic imported beer market. Thus, the study used the import demand function of imported beer to analyze the impact of the 'Priming Effect' on the consumption of imported beer by anti-national sentiment, indicating a significant drop in Japanese beer consumption in other countries. Therefore, this study used the imported beer import demand function by country to analyze the impact of the priming effect on imported beer consumption according to anti-national sentiment. As a result, in the case of imported beer consumption in other countries, it was estimated that indirect consumption substitution occurred considerably.