• The Korean Journal of Pain
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• v.36 no.2
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• pp.163-172
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• 2023

Background: Synaptic plasticity contributes to nociceptive signal transmission and modulation, with calcium/calmodulin-dependent protein kinase II (CaMK II) playing a fundamental role in neural plasticity. This research was conducted to investigate the role of CaMK II in the transmission and regulation of nociceptive information within the nucleus accumbens (NAc) of naïve and morphine-tolerant rats. Methods: Randall Selitto and hot-plate tests were utilized to measure the hindpaw withdrawal latencies (HWLs) in response to noxious mechanical and thermal stimuli. To induce chronic morphine tolerance, rats received intraperitoneal morphine injection twice per day for seven days. CaMK II expression and activity were assessed using western blotting. Results: Intra-NAc microinjection of autocamtide-2-related inhibitory peptide (AIP) induced an increase in HWLs in naïve rats in response to noxious thermal and mechanical stimuli. Moreover, the expression of the phosphorylated CaMK II (p-CaMK II) was significantly decreased as determined by western blotting. Chronic intraperitoneal injection of morphine resulted in significant morphine tolerance in rats on Day 7, and an increase of p-CaMK II expression in NAc in morphine-tolerant rats was observed. Furthermore, intra-NAc administration of AIP elicited significant antinociceptive responses in morphine-tolerant rats. In addition, compared with naïve rats, AIP induced stronger thermal antinociceptive effects of the same dose in rats exhibiting morphine tolerance. Conclusions: This study shows that CaMK II in the NAc is involved in the transmission and regulation of nociception in naïve and morphine-tolerant rats.

• Coupled systems mechanics
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• v.12 no.3
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• pp.199-220
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• 2023

This article presents a new analytical model to study the effect of porosity on the shear correction factors (SCFs) of functionally graded porous beams (FGPB). For this analysis, uneven and logarithmic-uneven porosity functions are adopted to be distributed through the thickness of the FGP beams. Critical to the application of this theory is a determination of the correction factor, which appears as a coefficient in the expression for the transverse shear stress resultant; to compensate for the assumption that the shear strain is uniform through the depth of the cross-section. Using the energy equivalence principle, a general expression is derived from the static SCFs in FGPB. The resulting expression is consistent with the variationally derived results of Reissner's analysis when the latter are reduced from the two-dimensional case (plate) to the one-dimensional one (beam). A convenient algebraic form of the solution is presented and new study cases are given to illustrate the applicability of the present formulation. Numerical results are presented to illustrate the effect of the porosity distribution on the (SCFs) for various FGPBs. Further, the law of changing the mechanical properties of FG beams without porosity and the SCFare numerically validated by comparison with some available results.

• Structural Engineering and Mechanics
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• v.40 no.3
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• pp.335-346
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• 2011

This paper deals with the bifurcations of non-semi-simple eigenvalues at critical point of Hopf bifurcation to understand the dynamic behavior of the system. By using the Puiseux expansion, the expression of the bifurcation of non-semi-simple eigenvalues and the corresponding topological structure in the parameter space are obtained. The zero-order approximate solutions in the vicinity of the critical points at which the multiple Hopf bifurcation may occur are developed. A numerical example, the flutter problem of an airfoil in simplified model, is given to illustrate the application of the proposed method.

• The Journal of the Acoustical Society of Korea
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• v.19 no.1E
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• pp.27-37
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• 2000

This paper presents a simplified analytical formulation for computing acoustic power radiation from a rectangular plate exposed to random forces such as turbulent boundary layer pressure fluctuations and arbitrary mechanical force in a subsonic flow field. The expression for the acoustic power is derived using modal expansion method and light fluid loading is assumed on the plate. In order to simplify the formulation for acoustic power due to combined excitations of mechanical forces and turbulent pressures, it is assumed that the structural damping of the plate is small and excitations are broadband random forces having frequency spectra above the convective coincidence. Under these assumptions, an approximate solution for the broadband acoustic power radiation from a plate excited by both turbulent pressures and arbitrary mechanical forces is obtained and evaluated considering the effect of modal coupling on the radiated acoustic power. An efficient method is also suggested to compute modal acoustic impedance in a moving fluid medium by using averaged Green function.

• Tribology and Lubricants
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• v.24 no.2
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• pp.90-95
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• 2008

An elastic-plastic contact analysis is developed using a semi-analytical method. The elastic contact is solved within a Hertz theorem. The reciprocal theorem with initial strains is then introduced, to express the surface geometry as a function of contact stress and plastic strains. The irreversible nature of plasticity leads to an incremental formulation of the elastic-plastic contact problem, and an algorithm to solve this problem is set up. Closed form expression, which give residual stresses and surface displacements from plastic strains, are obtained by integration of the reciprocal theorem. The distribution of contact stress, residual stress and plastic strain are obtained by the changed surface geometry.

• Journal of Power Electronics
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• v.18 no.3
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• pp.817-825
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• 2018

In this paper, a current hysteresis control with good decoupling properties for doubly-fed brushless induction machines (BDFIMs) has been proposed based on a generalized vector model. The independent control of the reactive power and speed for BDFIMs has been achieved by controlling the d-axis and the q-axis current of the control windings (CW). The proposed vector control method has been developed for the power winding (PW) flux frame. Experimental verification of a type Y180M-4 BDFIM prototype with 1/4 pole-pairs has been presented. Evidence of its good performance has been shown through experimental results.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.450-450
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• 2000

This paper presents a software design simulation method for controlling multiple mechanism carrier system (MMCS), which is mainly used in a wrapping machine or a case packing machine. This method uses a mechanical tool-work interactive model proposed in this paper, in order to represent the interactive behaviors between some tools and a work driven by their tools, in which low effect states of a work are defined. Based on this method, a 3-D simulation system has been built. It consists of shape modeling of each device, behavior definitions of tools, and control logic using if-then expression. By applying it to a ase packing machine having about 30 mechanical devices and 100 inputs/outputs for control, the effectiveness of this method has been shown in general verification of control logic specification in an early software design phase and the possibility of smooth communication tool between mechanical and software designers.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.48 no.11
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• pp.604-610
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• 1999

Vibration of a rotor-bearing system driven by an electric motor is a coupled phenomenon between mechanical characteristics and magnetic origins through the air-gap. With the advent of new high-energy magnets together with high precision motor applications, magnetic sources of vibration are becoming more serious. This paper investigates the transient whirl responses of a rotor system with purely mechanical origins and compares it with that of magnetically coupled origins. A perturbation method is applied to model the magnetic field associated with rotor eccentricity. Electromagnetic forces are obtained by the Maxwell stress method, which utilizes the analytical expression of radial flux density distribution. The FEM was applied to a rotor-motor system to illustrate magnetically coupled effects in rotor dynamics. Results show that magnetically coupled sources significantly affect the vibration of the rotor-motor system.

• KIEE International Transactions on Power Engineering
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• v.4A no.4
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• pp.227-235
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• 2004

This paper presents a new theoretical approach to energy-based power system analysis for multibus power transmission systems. On the basis of mechanical analogy, an exact energy integral expression is derived for lossy multi-bus systems through rigorous energy analysis. A simple rigid rod model of mechanical power transfer system is introduced to address the physical meanings of potential energy terms associated with transfer conductances as well as transfer susceptances. Finally, energy-based analysis has been proposed to show that the energy function has all information of the power system characteristics.

• Journal of Aerospace System Engineering
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• v.15 no.2
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• pp.1-9
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• 2021

In this paper, a thickness compensation function is introduced to consider the shear deformation and warping effect resulting from increased thickness in the composite multi-cell wing box. The thickness compensation function is used to perform the structure optimization of the multi-cell. It is determined by minimizing the error of an analytical formula using solid mechanics and the Ritz method. It is used to define a structural performance prediction expression due to the increase in thickness. The parameter is defined by the number of spars and analyzed by the critical buckling load and the limited failure index as a response. Constraints in structural optimization are composed of displacements, torsional angles, the critical buckling load, and the failure index. The objective function is the mass, and its optimization is performed using a genetic algorithm.