• 한국전문물리치료학회지
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• 제27권2호
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• pp.111-117
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• 2020

Background: The Functional Assessment of Chronic Illness Therapy (FACIT) for Dyspnea was developed to assess multidimensional dyspnea using two subscales (experience of dyspnea and functional limitation) and a total score. Objects: This study aimed to assess the reliability and validity of the Korean version of the FACIT-dyspnea 10-item short form questionnaire (FACIT-dyspnea-K). Methods: Subjects were 163 patients with cancer. Dyspnea-related scales (modified Medical Research Council scale [mMRC], European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 [EORTC QLQ-C30], Hospital Anxiety and Depression [HAD], and WHO Performance Scale) were used to validate the FACIT-dyspnea-K. Results: Internal consistency was confirmed by Cronbach's alpha values of 0.90 and 0.95 in factors 1 and 2, respectively. Convergence validity was determined by comparing the two factors and total score of the FACIT-dyspnea-K with conceptually related assessment tools measuring the physical and emotional effects of dyspnea, with which correlations ranged from 0.364 to 0.567. Criterion validity was established by significant differences in the FACIT-dyspnea-K score between groups when the patients were classified by performance status as assessed by the WHO performance scale. Furthermore, the FACIT-dyspnea-K showed notable correlations with other dyspnea scales (mMRC, EORTC QLQ-C30, and HAD) for cancer patients (r = 0.28 to 0.54). The test-retest reliability of the two factors and total score of the FACIT-dyspnea-K appeared to be excellent (Cronbach's alpha = 0.96 to 0.97). Conclusion: This study supports FACIT-dyspnea-K as a valid and reliable instrument to assess the dyspnea experience of cancer patients in clinical settings.

• 대한지역사회영양학회지
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• 제4권2호
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• pp.139-148
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• 1999

This study was designed to assess the iron nutritional status of girls at puberty in Kangnung area. The subjects consisted of 161 adolescents in sixth-grade in primary school and first-grade in middle school girls. Anthropometric measurements were taken for body weight, height, percentage of body fat, and circumferences of waist and hip. Nutrient intakes were assessed by modified 24-hour recall method. Food models and other measuring tools were also used. Fasting blood samples were obtained and analyzed for hemoglobin(Hb) concentration, hematocrit(Hct), serum iron(FE) and total iron binding capacity(TIBC). Mean values for Hb, Hct, Fe, TIBC, TS and serum ferritin were $13.6{\pm}0.9g/dl$, $39.6{\pm}3.9%, 91.3{\pm}36.3{\mu}g/dl$, $327.9{\pm}45.2{\mu}g/dl$, $28.3{\pm}11.8%$ and $37.4{\pm}24.2ng/ml$, respectively. Prevalence of iron deficiency greatly varied by indices from 4.8% when judged by Hb to 18.4% by serum Fe concentration. The Hb concentration was positively correlated with Hct(r=0.641), serum iron(r=0.266) and transferrin saturation(r=0.237)(p<0.05). On the other hand, serum ferritin concentration showed significantly negative correlation with TIBC(r=-0.572). Mean daily intake of iron was 14.94mg and heme iron intake was 1.13mg and which was 7.6% of total iron intake. Total absorbable iron calculated by the method of Mosen was 1.38mg and bioavailability of dietary iron was 9.3%. These results suggest that the prevalence of iron deficiency of pubertal girls is very high, therefore the guidelines for diet and social supports, such as, school food service system should be provided to improve their iron status in middle school students.

• Environmental Analysis Health and Toxicology
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• 제14권1_2호
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• pp.1-12
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• 1999

Recently, several new methods for the detection of genetic damages in vitro and in vivo based on molecular biological techniques were introduced according to the rapid progress in toxicology combined with cellular and molecular biology. Among these methods, mouse lymphoma thymidine kanase (tk) gene forward mutation assay, single cell gel electrophoresis (comet assay) and transgenic animal and cell line model as a target gene of lac I (Big Blue) and lac Z (Muta Mouse) gene mutation are newly introduced based on molecular toxicological approaches. The mouse lymphoma tk$\^$+/-/ gene assay (MOLY) using L5178Y tk$\^$+/-/ mouse lymphoma cell line is one of the mammalian forward mutation assays, and has many advantages and more sensitive than hprt assay. The target gene of MOLY is a heterozygous tk$\^$+/-/ gene located in 11 chromosome, so it is able to detect the wide range of genetic changes like point mutation, deletion, rearrangement, and mitotic recombination within tk gene or deletion of entire chromosome 11. The comet assay is a rapid, simple, visual and sensitive technique for measuring and analysing DNA breakages in mammalian cells, Also, transgenic animal and cell line models, which have exogenous DNA incorporated into their genome, carry recoverable shuttle vector containing reporter genes to assess endogenous effects or alteration in specific genes related to disease process, are powerful tools to study the mechanism of mutation in vivo and in vitro, respectively. Also in vivo acridine orange supravital staining micronucleus assay by using mouse peripheral reticulocytes was introduced as an alternative of bone marrow micronucleus assay. In this respect, there was an International workshop on genotoxicity procedure (IWGTP) supported by OECD and EMS (Environmental Mutagen Society) at Washington D. C. in March 25-26, 1999. The objective of IWGTP is to harmonize the testing procedures internationally, and to extend to finalization of OECD guideline, and to the agreement of new guidelines under the International Conference of Harmonization (ICH) for these methods mentioned above. Therefore, we introduce and review the principle, detailed procedure, and application of MOLY, comet assay, transgenic mutagenesis assay and supravital staining micronucleus assay.

• 전기학회논문지
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• 제57권3호
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• pp.514-517
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• 2008

Ubiquitous healthcare (U-healthcare) system is one of potential applications of embedded system. Conventional U-healthcare systems are used in health monitoring or chronic disease care based on measuring and transmission of various vital signs. However, future U-healthcare system can be of benefit to more people such as stroke patients which have limited activity by providing them proper medical care as well as continuous monitoring. Recently, an electric brain stimulation treatments have been found to be a better way compared to conventional ones and many are interested in using the method toward the treatment of stroke. In this study, we proposed a remote medical treatment system using ZigBee-based wireless electric brain stimulator that can help them to get a treatment without visiting their doctors. The developed remote medical treatment system connects the doctors to the brain stimulator implanted in the patients via the internet and ZigBee communication built in the brain stimulator. Also, the system receive personal information of the connected patients and cumulate the total records of electric stimulation therapy in a database. Doctors can easily access the information for better treatment planning with the help of graphical visualization tools and management software. The developed remote medical treatment system can extend their coverage to outdoors being networked with hand-held devices through ZigBee.

• 기본간호학회지
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• 제13권3호
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• pp.447-456
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• 2006

Purpose: This study was done to examine symptom experiences and related factors in angina patients. Method: The participants were 92 patients admitted to C university hospital between October and December 2004. The tools used were a questionnaire on symptom experience related to angina developed by Gensini(Coronary Angiographic Gensini Score). Global Assessment of Recent Stress Scale and a tool measuring performance of health behavior. Results: The mean score for symptom experience was relatively low (M=27.65, SD=18.44) as was the score for coronary severity (Gensini score) was 16.30 point (SD=18.04). The mean score for perceived stress was moderate (M=30.16, SD=12.26). Compliance was relatively good in these patients with angina (M=61.55, SD=7.60). Analysis of the correlation of symptom experience showed a statistically significant positive relationship with perceived stress (r=.410, p=.000). There was significant negative relationship (r=-.251, p=.016) between symptom experience and compliance. In the regression analysis, symptom experience was found to be significantly influenced by stress ($R^2$=.168, p=.000), age ($R^2$=.057, p=.002), and economic status ($R^2$=.061, p=.007). These variables explained 26.2% of the variance in symptom experience. Conclusion: The results of this study provide evidence that symptoms of angina can present not only as chest pain itself but also with fatigue, shortness of breath, and sleep disturbance as the most common symptoms.

• Imaging Science in Dentistry
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• 제47권1호
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• pp.11-15
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• 2017

Purpose: This study was performed to investigate the intra- and inter-observer variability in linear measurements with axial images obtained by PreXion (PreXion Inc., San Mateo, USA) and i-CAT(Imaging Sciences International, Xoran Technologies Inc., Hatfield, USA) CBCT scanners, with different voxel sizes. Materials and Methods: A cylindrical object made from nylon with radiopaque markers (phantom) was scanned by i-CAT and PreXion 3D devices. For each axial image, measurements were taken twice in the horizontal(distance A-B) and vertical (distance C-D) directions, randomly, with a one-week interval between measurements, by four oral radiologists with five years or more experience in the use of these measuring tools. Results: All of the obtained linear measurements had lower values than those of the phantom. The statistical analysis showed high intra- and inter-observer reliability (p=0.297). Compared to the real measurements, the measurements obtained using the i-CAT device and PreXion tomography, on average, revealed absolute errors ranging from 0.22 to 0.59 mm and from 0.23 to 0.63 mm, respectively. Conclusion: It can be concluded that both scanners are accurate, although the linear measurements are underestimations, with no significant differences between the evaluators.

• 한방재활의학과학회지
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• 제28권3호
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• pp.87-96
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• 2018

Objectives The purpose of this study is to provide more whiplash injury-specific measurement tools for Korean patients by measuring the validity and reliability of Korean version of Whiplash Disability Questionnaire (WDQ). Methods Bilingual clinicians translated the original WDQ into Korean. After consensus conference between researchers, it was back-translated into English. The pre-final version was completed and administered to 71 hospitalized patients diagnosed with whiplash injury. Validity was evaluated by concurrent validity. Reliability was assessed using Cronbach's ${\alpha}$ and intraclass correlation coefficient. Results The Korean WDQ showed good reliability with high internal consistency and intra-class correlation coefficient (Cronbach's ${\alpha}=0.96$, intraclass correlation coefficient [ICC]=0.82). Concurrent validity demonstrated positive correlations between Neck Disability Index, 36-Item Short Form Health Survey and WDQ. Conclusions The Korean version of WDQ is a valid and reliable tool for use as a measurement of whiplash injury in Korean patients, and it will be a very useful evaluation tool for both clinicians and researchers.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2008년도 정기학술발표대회 논문집
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• pp.222-226
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• 2008

건설산업은 불확실성이 높은 산업으로 이에 따른 비용효용성 향상 및 경쟁력 강화를 위한 연구가 다각적으로 진행되어 왔다. 린 건설의 대표적인 요소기술인 라스트플래너 시스템은 기존의 상의하달식 의사결정체계를 개선한 하의상달식 접근방식으로서, 모든 참여주체가 함께 중 단기 공정계획을 검토 시행하는 체계이다. 이와 같은 린 건설은 최근 들어 건설프로젝트에서 주도적인 역할을 하고 있는 발주자의 적극적인 참여와 전체 생애주기를 총괄할 수 있는 리더역량을 요구하는 방향으로 논의가 전개되고 있다. 그러나 발주자가 참여하는 린 건설이 성공하기 위해서는 건설주체 상호간에 요구하는 니즈(needs)수준과 이를 개선하기 위한 전략들이 우선적으로 고려되어야 한다. 본 연구에서는 건설 시공과정에서의 참여주체 니즈 요소를 규명 분석하고, 중점관리항목과 이들 항목들의 개선가능성을 도출하는 방법, 그리고 이를 기반으로 한 발주자 참여형 린 건설 협업 모델을 제시하였다.

• 재활치료과학
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• 제7권2호
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• pp.9-16
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• 2018

목적 : 본 연구의 목적은 뇌손상 환자의 신경학적 변화 측정도구인 뇌전도의 측정도구 및 방법, 평가와 분석방법을 알아봄으로써 임상영역에서 뇌전도 측정 시 기초자료를 제시하는 것에 있다. 연구방법 : 전자 데이터 베이스인 Pubmed, Science Direct를 사용하였으며, 주요검색 용어로 'Electroencephalography', 'stroke', 'intervention OR training'을 사용하였다. 결과 : 뇌전도는 두뇌-컴퓨터 인터페이스(Brain-computer interface)를 이용하여 재활의 효과를 뇌의 활성화 상태 변화로 측정할 수 있는 도구로 기능적 뇌 재조직화 매커니즘을 확인할 수 있는 것으로 나타났다. 뇌전도 측정도구의 경우 다양한 채널, 전극의 형태 및 전극 부착 부위로 구성되어 있으며, 결과해석에 사용되는 주파수 또한 다양하게 나타났다. 결론 : 뇌전도는 중재에 대한 효과성을 신경학적으로 확인할 수 있을 뿐만 아니라 효율적인 작업치료를 위한 중재전략을 마련하는데 사용될 수 있을 것으로 사료된다.

• 대한기계학회논문집A
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• 제35권1호
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• pp.53-58
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• 2011

초정밀 소형공작기계는 초정밀가공분야에서 마이크로/메조 스케일 가공품의 정밀제조기술의 핵심으로 개발되어 왔다. 소형초정밀기계의 기하학적 오차는 가공품의 품질에 큰 영향을 미치기 때문에 반드시 분석 및 보정되어야 한다. 기존 소형공작기계의 기하학적 오차는 주로 레이저 간섭계로 측정되었으나 한번의 설치로 모든 기하학적 오차를 측정할 수 없고 까다로운 절차를 따라야 한다. 그 대안으로써 PSD 로 구성된 측정시스템이 개발되었으나 측정가능거리가 PSD 의 유효영역에 한정되었다. 본 논문에서는 측정가능거리를 확장시키고 설치오차를 최소화하여 6-자유도 기하학적 오차를 측정하는 시스템을 제안하고 민감도 해석과 실험을 통하여 이 측정 시스템의 정확도를 증명하였다.