• Title/Summary/Keyword: mean time delay

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Association Between Gastric Emptying Time and Incidence of Cardiovascular Diseases in Subjects With Diabetes

  • Park, Hyung-Min;Park, Seon-Young;Chung, Jin Ook;Cho, Dong Hyuk;Park, Chang-Hwan;Kim, Hyun-Soo;Chung, Dong Jin;Choi, Sung-Kyu;Rew, Jong-Sun;Chung, Min Young
    • Journal of Neurogastroenterology and Motility
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    • v.25 no.3
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    • pp.387-393
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    • 2019
  • Background/Aims Delayed gastric emptying (GE) is associated with high morbidity and mortality in subjects with diabetes. The aim of this study is to investigate associations between GE time and the major cardiovascular events (coronary heart diseases and ischemic stroke) in diabetic subjects with upper gastrointestinal (UGI) symptoms. Methods Among 259 subjects with chronic UGI symptoms who underwent gastric emptying study (GES) over 13 years, 122 diabetic subjects without gastric surgery and/or rapid GE were enrolled in this study. We also gathered data about baseline demographics, clinical characteristics, estimated GE half-time (GE T½) and incidence of cardiovascular events following GES. Results The mean age of subjects was 64.0 ± 17.4 years. There were 86 women and 104 subjects with type 2 diabetes. There were 52 (42.6%) subjects with normal GE, 50 (41.0.%) subjects with mild delayed GE, and 20 (16.4%) subjects with marked delayed GE. During follow-up (median, 207 weeks), cardiovascular events occurred in 7 (13.5%) subjects with normal GE, 4 (8.0%) subjects with mild delayed GE and 7 (35.0%) subjects with marked GE (P = 0.015). Univariate analysis showed that GE T½ was significantly associated with incidence of cardiovascular events (crude OR, 1.74; 95% CI, 1.12-2.69; P = 0.014). In a multivariate model, association between GE T½ and incidence of cardiovascular events remained statistically significant after adjustment for baseline characteristics and comorbidities (adjusted OR, 1.94; 95% CI, 1.21-3.12; P = 0.006). Conclusion A delay of GE was associated with an increased incidence of cardiovascular events in diabetic subjects with chronic UGI symptoms.

Understanding on MR Perfusion Imaging Using First Pass Technique in Moyamoya Diseases (Moyamoya 질환에서 1차 통과기법을 이용한 자기공명관류영상의 이해)

  • Ryu, Young-Hwan;Goo, Eun-Hoe;Jung, Jae-Eun;Dong, Kyung-Rae;Choi, Sung-Hyun;Lee, Jae-Seung
    • Korean Journal of Digital Imaging in Medicine
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    • v.12 no.1
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    • pp.27-31
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    • 2010
  • The purpose of this study was to investigated the usefulness of MR perfusion image comparing with SPECT image. A total of pediatric 30 patients(average age : 7.8) with Moyamoya disease were performed MR Perfusion with 32 channel body coil at 3T from March 01, 2010 to June 10, 2010. The MRI sequences and parameters were as followed : gradient Echo-planar imaging(EPI), TR/TE : 2000ms/50ms, FA : $90^{\circ}$, FOV : $240{\times}240$, Matrix : $128{\times}128$, Thickness : 5mm, Gap : 1.5mm. Images were obtained contrast agent administrated at a rate of 1mL/sec after scan start 10s with a total of slice 1000 images(50 phase/1 slice). It was measured with visual color image and digitize data using MRDx software(IDL version 6.2) and also, it was compared of measurement with values of normal and abnormal ratio to analyze hemodynamic change, and a comparison between perfusion MR with technique using Warm Color at SPECT examination. On MR perfusion examination, the color images from abnormal region to the red collar with rCBV(relative cerebral blood volume) and rCBF(relative cerebral blood flow) caused by increase cerebral blood flow with brain vascular occlusion in surrounding collateral circulation advancement, the blood speed relatively was depicted slowly with blue in MTT(Mean Transit Time) and TTP(Time to Peak) images. The region which was visible abnormally from MR perfusion examination visually were detected as comparison with the same SPECT examination region, would be able to confirm the identical results in MMD(Moyamoya disease)judgments. Hymo-dynamic change in MR perfusion examination produced by increase and delay cerebral blood flow. This change with digitize data and being color imaging makes enable to distinguish between normal and abnormal area. Relatively, MR perfusion examination compared with SPECT examination could bring an excellent image with spatial resolution without radiation expose.

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Performance Analysis of the Gated Service Scheduling for Ethernet PON (Ethernet PON을 위한 Gated Service 스케줄링의 성능분석)

  • 신지혜;이재용;김병철
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.41 no.7
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    • pp.31-40
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    • 2004
  • In this paper, we analyze mathematically the performance of the gated service scheduling in the Interleaved Polling with Adaptive Cycle Time(IPACT) was proposed to control upstream traffic for Gigabit Ethernet-PONs. In the analysis, we model EPON MAC protocol as a polling system and use mean value analysis. We divide arrival rate λ into three regions and analyze each region accordingly In the first region in which λ value is very small, there are very few ONUs' data to be transmitted. In the second region in which λ has reasonably large value, ONUs have enough data for continuous transmission. In the third region, ONUs' buffers are always saturated with data since λ value is very large. We obtain average packet delay, average Queue size, average cycle time of the gated service. We compare analysis results with simulation to verify the accuracy of the mathematical analysis. Simulation requires much time and effort to evaluate the performance of EPONs. On the other hand, mathematical analysis can be widely used in the design of EPON systems because system designers can obtain various performance results rapidly. We can design appropriate EPON systems for varioustraffic property by adjusting control parameters.

COMPARISON OF DEMOGRAPHIC, CLINICAL, PSYCHOLOGICAL CHARACTERISTICS BETWEEN CHILDHOOD AND ADOLESCENT-ONSET SCHIZOPHRENIA (소아기 발병 및 청소년기 발병 정신분열병 환아의 인구학적, 임상적, 심리학적인 특성)

  • Chungh Dong-Seon;Lim Myung-Ho;Kim Soo-Kyoung;Jung Gwang-Mo;Hwang Jun-Won;Kim Boong-Nyun;Shin Min Sup;Cho Soo-Churl;Hong Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.16 no.2
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    • pp.219-230
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    • 2005
  • Objectives : This study was designed to compare the demographic data, clinical characteristics, developmental delay, and psychological tests between childhood-onset and adolescent-onset schizophrenic in-patients. Methods Medical records of the 17 childhood-onset (very early onset) Schizophrenia and 16 adolescent-onset (early onset) Schizophrenia in-patients were reviewed. Sex, age, psychiatric past history, prodromal symptoms and period, subtype, co-morbid disease, developmental delay, prescribed drug and dosage, treatment response, intelligence quotient (IQ), and Rorschach test were evaluated. Results : The mean admission age of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 12.69$({\pm}2.34)$ and 15.13$({\pm}1.04)$ years. The mean onset age of childhood-onset(very early onset) group and adolescent-onset (early onset) group were 10.79$({\pm}1.95)$ and 14.46$({\pm}0.82)$ years. The mean prodromal period of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 15.94$({\pm}12.33)$ and 8.06$({\pm}6.10)$ month. The time to remission period of childhood-onset (very early onset) group and adolescent-onset (early onset) group were 50.58$({\pm}24.67)$ and 30.06$({\pm}18.04)$ days. Longer time to remission period in childhood-osnet (very early onset) group was associated with earlier age of onset. The mean of total IQ, performance IQ, verbal IQ were at an average level. Discussion : Childhood-onset (very early onset) group and adolescent-onset (early onset) group Schizophrenia had different clinical and psychological features including prodromal period, and IQ subtests.

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Accuracy Analysis of GNSS-based Public Surveying and Proposal for Work Processes (GNSS관측 공공측량 정확도 분석 및 업무프로세스 제안)

  • Bae, Tae-Suk
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.36 no.6
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    • pp.457-467
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    • 2018
  • Currently, the regulation and rules for public surveying and the UCPs (Unified Control Points) adapts those of the triangulated traverse surveying. In addition, such regulations do not take account of the unique characteristics of GNSS (Global Navigation Satellite System) surveying, thus there are difficulties in field work and data processing afterwards. A detailed procesure of GNSS processing has not yet been described either, and the verification of accuracy does not follow the generic standards. In order to propose an appropriate procedure for field surveys, we processed a short session (30 minutes) based on the scenarios similar to actual situations. The reference network in Seoul was used to process the same data span for 3 days. The temporal variation during the day was evaluated as well. We analyzed the accuracy of the estimated coordinates depending on the parameterization of tropospheric delay, which was compared with the 24-hr static processing results. Estimating the tropospheric delay is advantageous for the accuracy and stability of the coordinates, resulting in about 5 mm and 10 mm of RMSE (Root Mean Squared Error) for horizontal and vertical components, respectively. Based on the test results, we propose a procedure to estimate the daily solution and then combine them to estimate the final solution by applying the minimum constraints (no-net-translation condition). It is necessary to develop a web-based processing system using a high-end softwares. Additionally, it is also required to standardize the ID of the public control points and the UCPs for the automatic GNSS processing.

The Effects of Sensory Integration Intervention Combined With Auditory Perception Training on Sensory Processing, Visual Perception and Attention of Children With Developmental Delay: Single-Subject Design (청지각 훈련과 병행한 감각통합치료가 발달지연 아동의 감각처리, 시 지각 발달, 주의집중에 미치는 영향: 개별실험연구)

  • Park, Mi-Young;Lim, Young-Myung;Kim, Hee
    • The Journal of Korean Academy of Sensory Integration
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    • v.15 no.2
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    • pp.66-79
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    • 2017
  • Objective : The purpose of this study is investigate the effects of sensory integration combined with auditory treatment on the sensory processing, visual perception and attention ability of children with developmental delay. Methods : A combined treatment of auditory training and sensory integration therapy was implemented to 3 children aged 4 to 7 and diagnosed with developmental delay during 9 weeks period from December 2016 to January 2017. ABA' design which is one of single subject research designs was used in this study. Baseline A had 4 sessions, intervention B had 15 sessions, and baseline A' had 4 sessions, so 23 sessions were applied in total. During the baseline A and A 'periods, visual perception ability was measured by K-DTVP-2 (Korea Developmental Test Visual Perception-2) and sensory processing ability was evaluated by sensory profile. The maintenance time of attention was measured with the absence of intervention for the baseline period, and for the intervention period, it was measured at 10 minutes break time which was provided after the intervention. The children's attention time during a fine motor task provided were measured using video recorder with the interval recording method, and the interval for the evaluation was 30 seconds. Results : No statistically significant difference were found in the visual perception function and sensory processing scores before and after treatment. Attention of participant A enhanced significantly while that of participant B and C did not improve significantly. Conclusion : It is hard to conclude that sensory integration therapy combined with auditory perception training has positive effects on visual perception function and attention of children with developmental delays. However, there were significant increase in attention and improvements in behavior related to sensory processing for some cases in this study. In further study, longer intervention periods and valid measurement need to be applied in order to get better results. And it is proposed that more studies need to be done to enhance evidence of auditory perception training as a mean to facilitate attention and to prepare learning.

Real-Time Video Quality Assessment of Video Communication Systems (비디오 통신 시스템의 실시간 비디오 품질 측정 방법)

  • Kim, Byoung-Yong;Lee, Seon-Oh;Jung, Kwang-Su;Sim, Dong-Gyu;Lee, Soo-Youn
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.46 no.3
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    • pp.75-88
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    • 2009
  • This paper presents a video quality assessment method based on quality degradation factors of real-time multimedia streaming services. The video quality degradation is caused by video source compression and network states. In this paper, we propose a blocky metric on an image domain to measure quality degradation by video compression. In this paper, the proposed boundary strength index for the blocky metric is defined by ratio of the variation of two pixel values adjacent to $8{\times}8$ block boundary and the average variation at several pixels adjacent to the two boundary pixels. On the other hand, unnatural image movement caused by network performance deterioration such as jitter and delay factors can be observed. In this paper, a temporal-Jerkiness measurement method is proposed by computing statistics of luminance differences between consecutive frames and play-time intervals between frames. The proposed final Perceptual Video Quality Metric (PVQM) is proposed by consolidating both blocking strength and temporal-jerkiness. To evaluate performance of the proposed algorithm, the accuracy of the proposed algorithm is compared with Difference of Mean Opinion Score (DMOS) based on human visual system.

A channel parameter-based weighting method for performance improvement of underwater acoustic communication system using single vector sensor (단일 벡터센서의 수중음향 통신 시스템 성능 향상을 위한 채널 파라미터 기반 가중 방법)

  • Kang-Hoon, Choi;Jee Woong, Choi
    • The Journal of the Acoustical Society of Korea
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    • v.41 no.6
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    • pp.610-620
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    • 2022
  • An acoustic vector sensor can simultaneously receive vector quantities, such as particle velocity and acceleration, as well as acoustic pressure at one location, and thus it can be used as a single input multiple output receiver in underwater acoustic communication systems. On the other hand, vector signals received by a single vector sensor have different channel characteristics due to the azimuth angle between the source and receiver and the difference in propagation angle of multipath in each component, producing different communication performances. In this paper, we propose a channel parameter-based weighting method to improve the performance of an acoustic communication system using a single vector sensor. To verify the proposed method, we used communication data collected from the experiment conducted during the KOREX-17 (Korea Reverberation Experiment). For communication demodulation, block-based time reversal technique which is robust against time-varying channels were utilized. Finally, the communication results showed that the effectiveness of the channel parameter-based weighting method for the underwater communication system using a single vector sensor was verified.

An Electromagnetic Shock Wave Generator Employing a Solenoid Coil for Extracorporeal Shock Wave Therapy: Construction and Acoustical Properties (체외 충격파 치료술을 위한 솔레노이드 코일을 이용한 전자기식 충격파 발생기: 구성 및 음향학적 특성)

  • Choi Min Joo;Lee Jong Soo;Kang Gwan Suk;Paeng Dong Guk;Lee Yoon Joon;Cho Chu Hyun;Rim Geun Hie
    • The Journal of the Acoustical Society of Korea
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    • v.24 no.5
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    • pp.271-281
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    • 2005
  • An electromagnetic type shock wave generator suitable for extracorporeal shock wave therapy has been constructed by employing a solenoid coil. The Property of the shock waves produced by the shock wave generator was evaluated using a needle hydrophone. It was shown that, as the capacitor discharging voltage increased from 8 to 18 kV, the Positive Peak Pressure (P+) of the shock wave increased non-linearly from 10 to 77 Wa. In contrast. the negative peak Pressure (f) varied between -3.2 and -6.8 MPa. had its absolute maximum of -6.9 ma at 14 kV The peak amplitudes P+ measured repeatedly under the same voltage setting varied within $5\;\%$ from mean values and this is very small compared to about $50\;\%$ for electrohydraulic type shock wave generators. It could be observed, from the hydrophone signal recorded over 1 ms. several sequential acoustic impulses representing bubble collapses. namely. acoustic cavitation. induced by the shock wave. A technique based on wavelet transformation was used to accurately measure the time delay between the 1st and 2nd collapse known to be closely related to the shock strength. It was observed that the measured time delay increased almost linearly from 120 to $700\;{\mu}s$ with the shock wave Pressure P+ increasing from 10 to 77 MPa.

SonazoidTM versus SonoVue® for Diagnosing Hepatocellular Carcinoma Using Contrast-Enhanced Ultrasound in At-Risk Individuals: A Prospective, Single-Center, Intraindividual, Noninferiority Study

  • Hyo-Jin Kang;Jeong Min Lee;Jeong Hee Yoon;Jeongin Yoo;Yunhee Choi;Ijin Joo;Joon Koo Han
    • Korean Journal of Radiology
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    • v.23 no.11
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    • pp.1067-1077
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    • 2022
  • Objective: To determine whether Sonazoid-enhanced ultrasound (SZUS) was noninferior to SonoVue-enhanced ultrasound (SVUS) in diagnosing hepatocellular carcinoma (HCC) using the same diagnostic criteria. Materials and Methods: This prospective, single-center, noninferiority study (NCT04847726) enrolled 105 at-risk participants (71 male; mean age ± standard deviation, 63 ± 11 years; range, 26-86 years) with treatment-naïve solid hepatic nodules (≥ 1 cm). All participants underwent same-day SZUS (experimental method) and SVUS (control method) for one representative nodule per participant. Images were interpreted by three readers (the operator and two independent readers). All malignancies were diagnosed histopathologically, while the benignity of other lesions was confirmed by follow-up stability or pathology. The primary endpoint was per-lesion diagnostic accuracy for HCC pooled across three readers using the conventional contrast-enhanced ultrasound diagnostic criteria, including arterial phase hyperenhancement followed by mild (assessed within 2 minutes after contrast injection) and late (≥ 60 seconds with a delay of 5 minutes) washout. The noninferiority delta was -10%p. Furthermore, different time delays were compared as washout criteria in SZUS, including delays of 2, 5, and > 10 minutes. Results: A total of 105 lesions (HCCs [n = 61], non-HCC malignancies [n = 19], and benign [n = 25]) were evaluated. Using the 5-minutes washout criterion, per-lesion accuracy of SZUS pooled across the three readers (72.4%; 95% confidence interval [CI], 64.1%-79.3%) was noninferior to that of SVUS (71.4%; 95% CI, 63.1%-78.6%), meeting the statistical criterion for non-inferiority (difference of 0.95%p; 95% CI, -3.8%p-5.7%p). The arterial phase hyperenhancement combined with the 5-minutes washout criterion showed the same sensitivity as that of the > 10-minutes criterion (59.0% vs. 59.0%, p = 0.989), and the specificities were not significantly different (90.9% vs. 86.4%, p = 0.072). Conclusion: SZUS was noninferior to SVUS for diagnosing HCC in at-risk patients using the same diagnostic criteria. No significant improvement in HCC diagnosis was observed by extending the washout time delay from 5 to 10 minutes.