• Journal of Gastric Cancer
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• v.1 no.3
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• pp.180-186
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• 2001

Purpose: The prognosis for early gastric cancer (EGC) is favorable, and the 10-year disease-specific survival rate is reported to be around $90\%$. The absolute number of recurred EGC is too small to assess the risk factors, so recruitment of a large number of cases for statistical analysis is very difficult. We carried out this study to analyze the incidence and the patterns of recurrence of EGC and to identify the clinicopathological risk factors for recurrence of EGC. Materials and Methods: The authors retrospectively investigated the follow-up records of 1418 patients who underwent a curative resection for EGC from Jan. 1984 to Dec. 1999 at the Korea Cancer Center Hospital and analyzed them with special reference to cancer recurrence. Results: In this retrospective study of 1418 cases, 43 patients died of a recurrence of gastric cancer, and 105 patients died of unrelated causes. The five-year and the ten-year overall survival rates were $89.6\%$ and $81.7\%$, respectively, while the five-year and the ten-year diseasespecific survival rates were $96.5\%$ and $94.3\%$, respectively. The recurrence patterns of the 45 recurred EGC were hematogenous metastasis (19 cases), lymph node (L/N) metastasis (8 cases), locoregional recurrence (2 cases), peritoneal seeding (3 cases), and combined form (13 cases). The mean time interval to recurrence was 38.6 months, and the number of delayed recurred cases after 5 years was 10 ($22.2\%$). Of the clinicopathologic factors, depth of invasion, L/N metastasis, macroscopic type, lymphatic invasion, and vessel invasion, were significant risk factors in the univariate analysis. However, in the multivariate analysis, only L/N metastasis was an independent prognostic factor. Conclusion: Based on the results of this study, L/N metastasis is an independent prognostic factor. Thus, in patients with node-positive disease, adjuvant therapy might be considered, and long-term close follow-up might facilitate early detection and treatment of recurrent disease due to delayed recurrence.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.29 no.2
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• pp.94-97
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• 2018

Background and Objectives : Fourth branchial cleft cyst is a rare congenital anomaly which cause a recurrent cervical abscess. Complete excision of fourth branchial cleft cyst is difficult because of a complicated fistula tract. In addition to attempting chemocauterization with trichloroacetic acid (TCA) to avoid surgical complications, authors performed an electrocauterization to close internal opening of pyriform sinus. Materials and Methods : We reviewed ten patients of fourth branchial cleft cyst underwent TCA chemocauterization and electrocauterization simultaneously. Clinical characteristics including patient informations, medical records, treatment results were analyzed retrospectively. Results : Interval time until diagnosed with fourth branchial cleft cyst was variable from several days to decades. Five patients had a history of incision and drainage. Mean follow up period was 36.1 months and all patients were treated with no recurrence. Conclusion : TCA chemocauterization with electrocauterization can be a effective choice to reduce recurrence rate and ensure safety of patients of fourth branchial cleft cyst.

• Journal of Korean Society of Water and Wastewater
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• v.23 no.5
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• pp.599-608
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• 2009

This manuscript covers the results of field investigation and lab-scale experiments to design a double-layered biofilter system to control urban storm runoff. The biofilter system consisted of a coarse soil layer (CSL) for filtration and fine soil layer (FSL) for adsorption and biological degradation. The variations of flow rate and water quality of runoff from a local expressway were monitored for seven storm events. Laboratory column experiments were performed using seven kinds of soil and mulch to maximize pollutants removal. The site mean concentration (SMC) of storm runoff from the drainage area (runoff coefficient: 0.92) was measured to be 203 mg/L for SS, 307 mg/L for $TCOD_{Cr}$, 12.3 mg/L for TN, 7.3 mg/L for ${NH_4}^+-N$, and 0.79 mg/L for TP, respectively. This study employed a new design concept, to cover the maximum rainfall intensity with one month recurrence interval. Effective storms for last ten years (1998-2007) in seoul suggested the design rainfull intensity to be 8.8 mm/hr Single layer soil column showed the maximum removal rate of pollutants load when the uniformity coefficient of CSL was 1.58 and the silt/clay contents of FSL was virtually 7%. The removal efficiency during operation of double layer soil column was 98% for SS and turbidity, 75% for TCODCr, 56% for ${NH_4}^+-N$, 87% for TP, and 73-91% for heavy metals. The hydraulic conductivity of the soil column, 0.023 cm/sec, suggested that the surface area of the biofilter system should be about 1% of the drainage area to treat the rainfall intensity of one month recurrence interval.

• Korean Journal of Head & Neck Oncology
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• v.12 no.2
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• pp.147-152
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• 1996

For advanced head and neck cancers that originate in midline structures, bilateral neck dissection should be considered even if the lymph nodes were negative clinically. But, many complications and mortalities may occur in synchronous bilateral neck dissection at sacrifing of both internal jugular vein. Therefore several types of bilateral neck dissection have been proposed, but the effective and safe methods were not determined yet. So, we have prefered the method of synchronous bilateral neck dissection with preserving one internal jugular vein at least. We operated 21 patients who might be expected high incidences of bilateral neck metastases with above type of neck dissection. We analyzed the data of 21 cases(42 sides) retrospectively. The results were as follows: 1) The primary sites were transglottic(33%), supraglottic(29%), hypopharynx(29%) and tongue base(9%). 2) Types of neck dissection were RND(4 sides), MND(7 sides), FND(16 sides), and SND (15 sides). 3) Postoperative complications were minimal and did not influenced morbidity. 4) Mean interval time of neck recurrence was 21 months. Overall neck recurrent rate after bilateral neck dissecton was 19%. In 19%, neck recurrence from positive lymph nodes was 63% and from negative lymph nodes was 37%. As a results, synchronous bilateral neck dissection with preservation of one internal jugular vein minimally should be done in cases which were suspected high incidence of bilateral lymph node metastases for cure and prevention of neck recurrence.

• Wind and Structures
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• v.15 no.5
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• pp.355-367
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• 2012

Atmospheric boundary layer winds experience two types of effects due to friction at the ground surface. One effect is the increase of the wind speeds with height above the surface. The second effect, called the Ekman layer effect, entails veering - the change of the wind speed direction as a function of height above the surface. In this study a practical procedure is developed within a database-assisted design (DAD) framework that accounts approximately for veering effects on tall building design. The procedure was applied in a case study of a 60-story reinforced concrete building, which also considered the dependence of veering effects on the orientation of the building. Comparisons are presented between response estimates that do not account for veering, and account for veering conservatively. For the case studied in this paper veering effects were found to be small.

• Wind and Structures
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• v.37 no.2
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• pp.117-131
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• 2023

Korea Design Standard (KDS) will be updated with two major revisions on the assessment of wind load and performance-based wind design (PBWD). Major changes on the wind load assessment are the wind load factor and basic wind speed. Wind load factor in KDS is reduced from 1.3 to 1, and mean recurrence interval (MRI) for basic wind speed increases from 100 years to 500 years considering the reduction of wind load factor. Additional modification is made including pressure coefficient, torsional moment coefficient and spectrum, and aeroelastic instability. Combined effect of the updates of KDS code on the assessment of wind load is discussed with the case study on the specified sites and building. PBWD is newly added in KDS code to consider the cases with various target performance, vortex-induced vibration, aeroelastic instability, or inelastic behavior. Proposed methods and target performance for PBWD in KDS code are introduced.

• The Journal of the Korean bone and joint tumor society
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• v.18 no.1
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• pp.1-6
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• 2012

Purpose: The purpose of this study was to analyze the results of treatment and prognosis of Marjolin's ulcer compared with primary squamous cell carcinoma. Materials and Methods: Fourteen patients treated for Marjolin's ulcer were analyzed. Twenty patients with primary squamous cell carcinoma treated during the same time period was the control group. Mean age was 61.2 years. There were 24 males and 10 females. The locations, TNM stages, histological grades, recurrence, metastasis, and survival rate were analyzed and compared between two groups. Results: The mean follow-up period was 54.8 months (range, 12-168 months). Local recurrences were found in 6 cases, 5 ones in Marjolin's ulcer patients, and one case in primary squamous cell carcinoma patients. The mean time interval between the initial presentation and occurrence of local recurrences was 9 months (range, 2-20 months). There were 6 metastases. 2 (14.3%) metastases were found in Marjolin's ulcer patients, and 4 (20.0%) metastases in primary squamous cell carcinoma patients. Total events (metastasis or local recurrence) were found in 10 pateients, 6 of them in Marjolin's ulcer group, and the remaining four in primary group. 5-year disease-free survival rate was 64.3% in Marjolin's ulcer group and 95.0% in primary squamous cell carcinoma group. Conclusion: Squamous cell carcinomas originating as Marjolin's ulcers revealed higher recurrence rate and lower survival rate despite of aggressive treatment. Therefore, new treatment modalities should be developed for improving outcomes.

• Wind and Structures
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• v.11 no.6
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• pp.427-440
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• 2008

Estimates of wind-induced wind effects on tall buildings are based largely on 1980s technology. Such estimates can vary significantly depending upon the wind engineering laboratory producing them. We describe an efficient database-assisted design (DAD) procedure allowing the realistic estimation of wind-induced internal forces with any mean recurrence interval in any individual member. The procedure makes use of (a) time series of directional aerodynamic pressures recorded simultaneously at typically hundreds of ports on the building surface, (b) directional wind climatological data, (c) micrometeorological modeling of ratios between wind speeds in open exposure and mean wind speeds at the top of the building, (d) a physically and probabilistically realistic aerodynamic/climatological interfacing model, and (e) modern computational resources for calculating internal forces and demand-to-capacity ratios for each member being designed. The procedure is applicable to tall buildings not susceptible to aeroelastic effects, and with sufficiently large dimensions to allow placement of the requisite pressure measurement tubes. The paper then addresses the issue of accounting explicitly for uncertainties in the factors that determine wind effects. Unlike for routine structures, for which simplifications inherent in standard provisions are acceptable, for tall buildings these uncertainties need to be considered with care, since over-simplified reliability estimates could defeat the purpose of ad-hoc wind tunnel tests.

• Journal of Gastric Cancer
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• v.3 no.4
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• pp.191-194
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• 2003

Purpose: Neuroendocrine carcinomas of the stomach account for only about $0.3\%$ of all gastric tumors. The prognosis of this disease is very poor compared with the common type of gastric adenocarcinoma. The purpose of this retrospective study was to review the clinicopathologic features of 18 cases of this unusual gastric tumor and to establish a treatment strategy for this tumor. Materials and Methods: Excluding 2 cases of non-curative resection and 1 case of operative mortality, 18 cases of typical neuroendocrine carcinoma who had curative resection from January 1991 to December 2000 at Asan Medical Center were analyzed; 6841 gastric cancer patient were treated surgically during the same period. Results: The mean age at the time of diagnosis was 58.6 years (range: $35\∼75$ yr). Sixteen patients were male, and two were female. Eleven tumors ($61.1\%$) developed in the lower part of the stomach, three ($16.7\%$) in the middle part, and three ($16.7\%$) in the upper part. One tumor involved the entire stomach. Eight cases ($44.4\%$) were Borrmann type 2, and six case ($33.3\%$) were Borrmann type 3. The mean tumor size was 6.94 cm (range: $0.6\∼15$ cm). Nine cases ($50\%$) showed recurrence of the disease, and eight of them died within 20 months. Of the nine recurred cases, 7 cases ($77.8\%$) showed liver metastasis. The mean disease-free interval was 6.8 months (range: $2.5\∼11$ months) after surgical resection, and the mean survival was 17.9 months (range: $8\∼40$ months) for recurrence cases. One patient with liver metastasis was treated with a liver-wedge resection just after diagnosis and was still alive for 37.5 months postoperatively. There were 9 deaths after the median follow- up period of 40 months (range: $8\∼72$ months). Conclusion: Gastric neuroendocrine carcinomas frequently recur at the liver, even in early stage cancer, and have a poor prognosis. We experienced a case of successful control of hepatic metastasis by surgical resection and a case of a small cell carcinoma which was successfully controlled with systemic chemotherapy.

• Journal of Acupuncture Research
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• v.26 no.1
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• pp.29-37
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• 2009

Objectives : This study was performed to categorize and define causes of recurrent peripheral facial nerve palsy. Methods : 54 patients was identified with recurrent peripheral facial nerve palsy among 726 patients who visited the Facial Palsy Center in East-West Neo Medical Center between May 2006 and August 2008. We reviewed the medical records including gender, age, laterality, number of recurrence, primary onset age, interval between recurrences, accompanied disease(e.g. DM, HTN), and axonal loss. Results : Patients whose primary palsy onset was before their second decade had a higher possibility of recurrence and tended to recur more than twice. Double-episode ipsilaterally recurrent group showed definitely worse result of axonal loss compared with non-recurrent group and single-episode ipsilaterally recurrent group. But There was no statistically significant difference between mean axonal loss of the non-recurrent group and single-episode ipsilaterally recurrent group. Conclusions : This study was designed for 54 patients and further studies are necessary.