• 한국기계가공학회지
• /
• 제16권6호
• /
• pp.87-94
• /
• 2017

Hot stamping processes are possible for tensile strength 1.4 GPa but the strength reduction is appeared from the cooling performance unbalance. And the strength of roll forming process is below than that of hot stamping process owing to using the steel which is lower strength of boron steel. In this study, We provide roll forming process asssisted high-frequency induction heating to solve the problem of conventional one. The experiments were carried out at under various sill side part conditions: high-frequency induction heating conditions of 15, 18, 21, 24, 27 and 30 kW. The high-frequency induction heating temperature was checked with Infrared camera and the sill side parts of mechanical properties and microstructure were measured. The heating temperature of high frequency induction was measured to max $850^{\circ}C$ under the coil power of 30 kW. The tensile strength was 1.5 GPa and hardness was 490 Hv. The martensite structure was discovered under coil power of 30 kW. The weight of steel material sill side having thickness 1.5 mm and the boron steel sill side having thickness 1.2 mm were compared to weight effect. The boron steel sill side reduced 11.5% compared to steel. Consequently, manufacturing process of 1.5 giga-grade's sill side part was successfully realized by the roll forming assisted high-frequency induction heating methods.

• 한국정보과학회논문지:소프트웨어및응용
• /
• 제32권1호
• /
• pp.1-9
• /
• 2005

본 논문에서는 패턴 분류를 위한 수정된 퍼지 최대최소 신경망 모델을 제안하고 그의 유용성을 고찰한다. 이를 위하여 하이퍼박스 내에서 각 특징들에 대하여 가중치 요소론 갖는 새로운 하이퍼큐브 소속함수를 정의한다. 이 가중치 요소는 분류과정에서 임의의 클래스에 대한 각 특징의 상대적인 기여도를 반영한다. 본 연구에서는 이를 위하여 새롭게 정의된 하이퍼박스 생성, 확장 및 축소의 3단계로 이루어지는 학습 방법론을 소개한다. 또한 제안된 모델을 기반으로 하여 학습된 분류기로부터 하이퍼박스 소속함수와 연결가중치를 사용하여 주어진 클래스에 대한 특징의 연관도를 산출하는 형태의 이른바 특징 분석 기법을 제안한다. 이를 위하여 세부적으로 각 특징에 대하여 연관도 척도와 퍼지 소속함수간의 유사도 척도를 정의한다. 또한 실제 패턴 분류문제에 적용한 실험결과를 통하여 제안된 이론의 타당성을 평가한다.

• Journal of Pharmaceutical Investigation
• /
• 제30권4호
• /
• pp.235-239
• /
• 2000

Ipriflavone (3-phenyl-7-isopropoxy-4H-1-benzopyran-4-one, IP) is a well-known antiosteoporotic drug with poor bioavailability. In the previous study, we reported that the IP formulation prepared by spray-drying method with polyvinylpyrrolidone (PVP) (SIP) was very effective in improving the bioavailability of IP. In this study, we examined the effects of molecular weight and mixture ratios of PVP to IP on the systemic absorption of IP following oral administration of SIP at a dose of 50 mg/kg to rats. In the effect of molecular weight, the Cmax of spray-dried IP with PVP K30 (SIP-K30) was significantly higher than those of spray-dried IP with PVP 360 (SIP-360), spray-dried IP with PVP K90 (SIP-K90), and spray-dried IP with PVP K17 (SIP-K17) (p<0.05). The AUC of SIP-K30 was about 2, 3, and 5.5 times higher than those of SIP-360, SIP-K90, and SIP-K17, respectively. The AUC value of SIP-K30 was significantly greater than those of SIP-K17 and SIP-K90 (p<0.05) except for SIP-360. In the ratio of PVP K30 to drug, the $C_{max}$ and the AUC value of 3 : 7 IP-PVP solid dispersion were similar to those of 5 : 5 IP-PVP and significantly higher than those of the other solid dispersions (p<0.05). It was concluded that the spray-dried IP with PVP K30 at the ratio of 3:7 (w/w) was the best formulation for improving the bioavailability of IP.

• 한국작물학회지
• /
• 제47권2호
• /
• pp.75-79
• /
• 2002

This study conducted to elucidate the change of the cation content (Na$^{+}$, $K^{+}$, and $Ca^{2+}$), the L-proline content, and the sugar and starch content in the stems, roots, and leaves of three cultivars of the 30 days old seedling soybeans (Glycine max L. cv. Danwonkong, Hwang-keumkong, and Kwangankong) after 100 mM NaCl stress containing 1/2 Hoaglands nutrient solution in the sand culture. The reduction of the dry matter weight after 100 mM NaCl treatment among cultivars was higher in the order of Kwangankong, Danwonkong, and Hwang-keumkong. The highest reduction of the dry matter weight was occurred at the roots among three parts of plant. The Na$^{+}$ content increased with NaCl treatment in overall and specially greatly increased in roots and stems. The $K^{+}$ and $Ca^{2+}$ content decreased with NaCl treatment at the roots and stems. The $K^{+}$ content, however, at the leaves increased in all three cultivars with the NaCl treatment. The L-proline content with NaCl stress increased greatly. The increment of the L-proline content at the stems and roots of Hwangkeumkong was lower than that of other two cultivars, K wangankong and Danwonkong. The sugar content decreased with NaCl treatment at the stems and leaves. The starch content also decreased at the stems and leaves with NaCl treatment.aCl treatment.

• 한국식품조리과학회지
• /
• 제29권1호
• /
• pp.19-28
• /
• 2013

This study was carried out to investigate the quality characteristics and storage of noodle with added flowering cherry fruit powder. Wet noodles were prepared at concentration of 1, 2, and 3% (w/w) of the fruit based on flour weight. Moisture content of the noodles with or without flowering cherry fruit powder was 33.09~33.50%. Ca, K and Mg contents of flowering cherry fruit noodle were increasing at increasing concentrations of flowering cherry fruit powder. Cooked weight, volume, and water absorption decreased with increased fruit powder, whereas turbidity increased. For Hunter's color values of noodles, L (lightness) and b (yellowness) values decreased with increasing concentration of flowering cherry fruit powder, whereas a (redness) value increased. For mechanical characteristics of the noodles, adhesiveness of cooked noodle with flowering cherry fruit powder were higher than those of control. The pH of flowering cherry fruit noodle was lower than that of control during storage. Bacterial counts of wet noodle with flowering cherry fruit powders were lower than those of the control on the 10th day of storage at $5^{\circ}C$. From the sensory evaluation of 20's, texture, taste, and overall preference were not significantly different between the control and the fruit groups, but the color scores of 2% and 3% flowering cherry fruit noodle were significantly higher than that of 1% fruit noodle (p<0.05). In 40's sensory evaluation, color and overall preference scores of flowering cherry fruit noodle were significantly higher than those of control. In conclusion, the results of this study were suggested that the addition of flowering cherry fruit powder in combination with flour was tended to improve antimicrobial effects during storage when compared to control.

• Journal of Plant Biotechnology
• /
• 제45권4호
• /
• pp.328-332
• /
• 2018

Soybean [Glycine max (L.) Merr.] seed is an important dietary source of protein, oil, carbohydrate, isoflavone and other various nutrients for humans and animals. However, there are anti-nutritional factors in the raw mature soybeans. Kunitz trypsin inhibitor (KTI) protein and stachyose are the main anti-nutritional factors in soybean seed. The ${\alpha}^{\prime}$-subunit of ${\beta}$-conglycinin protein exhibit poor nutritional and food processing properties. The genetic removal of the KTI and ${\alpha}^{\prime}$-subunit proteins will improve the nutritional value of the soybean seed. The objective of this research was to develop a new soybean strain with KTI and ${\alpha}^{\prime}$-subunit protein free ($titicgy_1cgy_1$ genotype) and proper agronomic traits. A breeding population was developed from the cross of the Bl-1 and 15G1 parents. A total of 168 $F_2$ seeds from the cross of the BL-1 and 15G1 parents were obtained. The segregation ratios of 9: 3: 3: 1 ($104Ti\_Cgy_{1\_}:\;30Ti\_cgy_1cgy_1:\;21cgy_1cgy_1Ti\_:\;13titicgy_1cgy_1$) between the Ti and $Cgy_1$ genes in the $F_2$ seeds were observed (${\chi}^2=5.12$, P=0.5-0.10). Two $F_4$ plant strains with proper agronomical traits and $titicgy_1cgy_1$ genotype (free of both KTI and ${\alpha}^{\prime}$-subunit protein) were selected and harvested. 2 strains (S1 and S2) had yellow seed coats and hilum. The plant height of the S1 strain was 65 centimeters. The 100-seed weight was 29.2 g. The plant height of the S2 strain was 66 centimeters and 100-seed weight was 26.2 g. The two strains selected in this research will be used to improve the new cultivar that will be free of the KTI and ${\alpha}^{\prime}$-subunit proteins.

• 대한정형도수물리치료학회지
• /
• 제24권2호
• /
• pp.43-49
• /
• 2018

Background: In this study, the importance of constipation and back pain was assessed by regression analysis of the effects of stress, dietary habits, and water intake on constipation in women in their twenties and the influence of constipation and body mass index (BMI) To provide basic data. Methods: This study selected 109 having constipation of 120 students attending G University in Gwangju and eating habits, water intake level, stress and BMI. Trigger point at the tip of erector spina was palated with tenderness set in order to examine whether muscle tenderness and actual low back muscle tenderness level were same and left and right parts were measured three times and average of Max values was used. We examined the effect of constipation on low back pain and examined constipation and BMI to determine whether they affected low back pain. Results: There was no significant difference in eating habit although there was a significant difference in the effect of stress and water intake on constipation. Constipation had significant difference in back pain. However, there was no significant difference in BMI, normal weight, overweight, and obesity except for low body weight. Conclusions: This study found that constipation was associated with stress levels, water intake, and back pain. In conclusion, this study suggests basic data to prevent and treat constipation-related back pain, and recommends plenty of water intake, proper exercise and stress management to prevent constipation.

• 한국운동역학회지
• /
• 제31권3호
• /
• pp.176-182
• /
• 2021

Objective: The purpose of this study is to investigate whether the athletic knee show greater rotation and translation movement than non-athletic knee during the treadmill walking with their preferred speed in a complete gait cycle. Method: Thirty young and healthy male subjects participated in the study, fifteen handball players (mean age: 19.6 ± 1.4 years old, mean weight: 85 ± 11.9 Kg, mean height: 179.8 ± 4.7) and fifteen non-athletes (mean age: 22.8 ± 1.2 years old, mean weight: 74.5 ± 8.6 Kg, mean height: 175 ± 5.9). Three-dimensional positional coordinate of lower limb during treadmill walking were analyzed. Results: There were significant differences (t (22.014)=1.585, p=0.127 in the range of internal and external rotation with mean value for handball player (M=14.4513, SD=2.3839) was higher than non-athletes (M=13.3327, SD=1.337). The magnitude of the difference in the means (mean difference=1.11867, 95% CI: -0.34489 to 2.5822) was significant. There were also significant differences (t (17.956)=1.654, p=0.116 in the max abduction and adduction with mean value for handball player (M=5.7160, SD=2.49281) was higher than non-athletes (M=4.5773, SD=0.94667). The magnitude of the difference in the means (mean difference=1.138, 95% CI: -0.30805 to 2.58539) was significant. At significance level 0.05. Conclusion: Finding of this study suggest that to understand the actual characteristic of knee motion studies have to be done in different walking and running trial at variable speed.

• 한국의학물리학회지:의학물리
• /
• 제25권3호
• /
• pp.167-175
• /
• 2014

본 연구는 IMRT가 적용된 성문암 환자에 대하여 CBCT영상과 변형영상 정합기법을 이용하여 치료기간 동안 실제 환자에게 전달되는 선량 변화를 평가하고자 하였다. B-spline 알고리즘을 사용한 변형영상정합 시스템을 통해 치료 중 1주 간격으로 얻은 CBCT를 재구성하고 치료계획을 재계산하여 종양과 결정장기의 선량 분포를 비교하였다. 체중에 따른 체적변화는 3~5 주부터 평균 1.38~2.04 kg로 증가하였으며 체표면의 변화는 평균 2.1 mm로 감소하였다. 또한, 3주 이후의 경동맥에 전달된 선량은 계획되었던 값보다 최대 8.76%로 증가하였고, 갑상선샘은 26.4%로 감소하였다. 종양의 물리적의 평가인자인 PITV, TCI, rDHI, mDHI 그리고, CN은 치료 계획된 값보다 각각 평균 4.32%, 5.78%, 44.54%, 12.32% 그리고, 7.11%로 감소하였다. PTV에 대한 $D_{max}$는 평균 2.99% 증가하였고, $D_{mean}$, $V_{67.50}$, $D_{95}$는 각각 평균 1.52%, 5.78%, 11.94%로 감소하였다. 체중변화에 따른 체적의 변화가 없더라도 체형변화는 발생하였고, 좁은 여유마진을 가지는 IMRT는 이러한 변화에 민감하게 반응하였다. 성문암에 대한 IMRT 적용 시 환자의 체중변화를 관찰과 함께 변화를 기록하고 치료 중 변형영상정합 시스템을 이용하여 선량분포를 평가할 필요가 있다. 최종적으로 치료 중 실제 전달되는 선량평가는 적응형치료계획을 통하여 확인하고 정확한 선량전달이 필요하다고 사료된다.

• Food Science and Biotechnology
• /
• 제17권3호
• /
• pp.679-682
• /
• 2008

A lactic acid bacterium producing an antimicrobial substance against Escherichia coli O157:H7 was isolated from raw milk and identified as Lactobacillus amylovorus ME-1. In addition to E. coli O157 :H7, the antimicrobial substance also inhibited the growth of Bacillus cereus, Listeria monocytogenes, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pyrogenes, and Yersinia enterocolitica. The antimicrobial substance was stable at pH 2-12 and $121^{\circ}C$ for 15 min and insensitive to proteinase K, protease, amylase, and catalase. Purification of the antimicrobial substance was conducted through methanol and acetonitrile/ethylacetate extraction, ultrafiltration with a 500 Da cutoff, thin layer chromatography (TLC) with silicagel 60, and high performance liquid chromatography (HPLC) with a $C_{18}$ reverse phase column. The ${\lambda}_{max}$ of the purified antimicrobial substance was determined as 192 nm by ultra violet (UV) scanning, while the molecular weight was estimated as 453 Da based on the mass spectrum. Accordingly, the current results suggest that the antimicrobial substance from the L. amylovorus ME-1 was not a bacteriocin, but rather a new non-proteinaceous substance distinct from acidophilin, acidolin, diacetyl, and reuterin.