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New Design of Wind-Mill Type Ultrasonic motor with High Torque (고토크를 내는 풍차형 초음파 전동기의 새로운 설계)

  • 김우태;김진수
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2000.11a
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    • pp.181-183
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    • 2000
  • Ultrasonic Motors of Wind-Mill type(diameter in 11.35mm, thickness in 2.8mm, and 1.44g weight) using Piezoelectric Ceramics have been developed. In recent study, Maximum torque in 100$V_{max}$, 105.8kHz was 7.2 ${\mu}$N$.$m, and bidirectional revolution using single-phase AC was presented. However, it is difficult to use because of small torque. Thus, in present study, new type of Wind -Mill Type Ultrasonic Motor of was designed as stator' structure was changed

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Forensic Engineering Study on the Explosion Accident Investigation of the Centrifugal Casting Machine Using ADINA FSI (ADINA FSI를 활용한 원심주조기 폭발사고 원인 규명에 관한 법공학적 연구)

  • Kim, Eui-Soo;Kim, Jong-Hyuk;Kim, Moo-Gon
    • Journal of the Korean Society of Safety
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    • v.26 no.4
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    • pp.27-33
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    • 2011
  • Forensic Engineering is the area covering the investigation of products, structures that fail to perform or do not function as intended, causing personal injury or damage to property. To investigate explosion accident of the centrifugal casting machine in terms of the forensic engineering, in this paper, the computing simulation using ADINA FSI has performed to investigate that the effect of the Check-Pin fracture by the flow phenomena and molten metal weight and the mechanical properties test of the accident Check-Pin has performed using the instrumented indentation technique. Through these studies, the safety accident that may occur in centrifugal casting machine can be minimized by performing specialized and systematic investigation of the accident cause in terms of the forensic engineering.

The Effect of Vegetable Extracts on the Activity of Alcohol Dehydrogenase from Saccharomyces cerevisiae

  • Jung, Soon-Teck;Kang, Bae-Kwang
    • Preventive Nutrition and Food Science
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    • v.6 no.4
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    • pp.224-229
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    • 2001
  • We investigated the effects of bean sprouts (Glycine max), dropwort (Oenanthe javanica), and radish (Raphanus sativus var. hortensis for. acanthiformis) extracts on alcohol dehydrogenase (ADH). The extracts from three kinds of vegetables were prepared by extracting with boiling water, distilling water, and ethyl alcohol. Among extracts, boiling water extract showed the highest activating effect on ADH, respectively and distilled water extract had a greater effect on ADH activation than that of alcohol extract. The ADH facilitating effect of bean sprout extract by distilled water was significantly higher than dropwort or radish, hut the effect of the bean sprout extract by ethyl alcohol was lower than others. The facilitating effect on ADH of mixture extracts of bean sprout and dropwort were mixed at 1 : 1 mixture of boiled-water extract showed the highest effectiveness. And bean sprout extract separated below 3000 molecular weight (MW) range of extract fraction had greater ADH activity than large MW parts.

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Effect of temperature on pharmacokinetics of nalidixic acid and piromidic acid in black rockfish Sebastes schlegeli following oral administration (조피볼락, Sebastes schlegeli에 경구투여된 nalidixic acid 및 piromidic acid의 약물동태에 미치는 수온의 영향)

  • Jung, Sung-Hee;Seo, Jung-Soo;Jee, Bo-Young;Kim, Jin-Woo;Park, Myoung-Ae
    • Journal of fish pathology
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    • v.24 no.1
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    • pp.29-37
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    • 2011
  • Effects of temperature ($13{\pm}1.5^{\circ}C$, $23{\pm}1.5^{\circ}C$) on the pharmacokinetic properties of nalidixic acid (NA) and piromidic acid (PA) were studied after oral administration to cultured black rockfish, Sebastes schlegeli. Serum concentrations of NA and PA were determined using HPLC-UV detector after a single dosage of 60 mg/kg body weight. At $23{\pm}1.5^{\circ}C$, the peak serum concentrations of NA and PA, which attained at 24 h post-dose, were 5.87 and $0.43\;{\mu}g/ml$, respectively. At $13{\pm}1.5^{\circ}C$, the peak serum concentrations of NA and PA, which attained at 10 h post-dose, were 6.22 and $1.57\;{\mu}g/ml$, respectively. Better absorption of PA was noted at $13{\pm}1.5^{\circ}C$ compared to $23{\pm}1.5^{\circ}C$. However, absorption of NA was not affected significantly by temperature. The elimination of NA and PA from serum of black rockfish was considerably faster at $23{\pm}1.5^{\circ}C$ than at $13{\pm}1.5^{\circ}C$. The kinetic profile of absorption, distribution and elimination of NA and PA in serum were analyzed by fitting to a one compartment model, with WinNonlin program. The AUC, $T_{1/2}$, $T_{max}$ and $C_{max}$, respectively, were: $161.25\;{\mu}g{\cdot}h/ml$, 0.15 h, 12.29 h and $8.91\;{\mu}g/ml$ at $23{\pm}1.5^{\circ}C$, and $134.12{\mu}g{\cdot}h/ml$, 0.18 h, 8.79 h and $5.00\;{\mu}g/ml$ at $13{\pm}1.5^{\circ}C$ with NA; $41.57\;{\mu}g{\cdot}h/ml$, 0.58 h, 8.24 h and $0.21\;{\mu}g/ml$ at $23{\pm}1.5^{\circ}C$, and $40.36\;{\mu}g{\cdot}h/ml$, 0.59 h, 5.04 h and $1.20\;{\mu}g/ml$ at $13{\pm}1.5^{\circ}C$ with PA.

Pharmacokinetics of cefadroxil after oral administration in olive flounder, Paralichthys olivaceus (Cefadroxil의 경구투여에 따른 넙치(Paralichthys olivaceus)에서의 약물동태학 연구)

  • Lee, Ji-Hoon;Park, Kwan Ha
    • Journal of fish pathology
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    • v.31 no.1
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    • pp.23-34
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    • 2018
  • The pharmacokinetic properties of cefadroxil (CDX) were studied after oral administration for 7 days to cultured olive flounders (average 660 g), Paralichthys olivaceus. For examination of pharmaco-kinetic profiles, CDX of 45 to 225 mg/kg body weight was administered at two different water temperatures, $13{\pm}3^{\circ}C$ or $22{\pm}3^{\circ}C$. CDX concentrations were determined in muscle, plasma, gastrointestinal tract, hematopoietic organs and liver by HPLC-MS/MS. Muscle samples were taken at 0.25, 0.5, 1, 3, 7, 14 and 28 days post dose, whereas plasma, gastrointestinal tract, hematopoietic organs and liver concentrations were measured at 1, 3, 7, 14 and 28 days post-dosing. The kinetic profiles of $C_{max}$, $T_{max}$, $T_{1/2}$ of CDX were analyzed by fitting to a non-compartmental model with PKSolver program. The following pharmacokinetic parameters were obtained with oral administration of 45 and 225 mg/kg at 13 and $22^{\circ}C$ in muscle, plasma, gastrointestinal tract, hematopoietic organs and liver, respectively: $C_{max}$ (maximum tissue concentration)=$985.98-5,032.86{\mu}g/kg$, $5,670.99-38,922.23{\mu}g/l$, $2,457.27-10,192.78{\mu}g/kg$, $886.04-3,070.87{\mu}g/kg$ and $1,188.15-3,814.33{\mu}g/kg$; $T_{max}$ (time for maximum concentration)= every 1 day; $MRT_{0-{\infty}}$ (mean residence time)= 1.51-4.74, 2.12-3.06, 4.25-13.18, 1.37-18.66 and 1.78-29.76 days; $T_{1/2}$ (half-life)= 1.08-3.47, 1.14-5.42, 3.56-10.99, 1.17-14.93 and 1.25-28.55 days.

Pharmacokinetics of Propentofylline and the Quantitation of Its Metaolite Hydroxypropentofylline in Human Volunteers

  • Kwon, Oh-Seung;Chung, Youn-Bok;Kim, Min-Hee;Hahn, Hoh-Gyu;Rhee, Hee-Kyung;Ryu, Jae-Chun
    • Archives of Pharmacal Research
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    • v.21 no.6
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    • pp.698-702
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    • 1998
  • Propentofylline (PPF, 3-methyl-1-(5-oxohexyl)-7-propylxanthine) has been reported to be effective for the treatment of both vascular dementia and dementia of the Alzheimer type. The pharmacological effects of PPF may be exerted via the stimulation of nerve growth factor, increased cerebral blood flow, and inhibition of adenosine uptake. The objectives of this experiment are to determine the kinetic behavior of PPF, to identify, and to quantify its metabolite in human. Blood samples were obtained from human volunteers following oral administration of 200mg of PPF tablets. For the identification and quantification of the metabolite, 3-methyl-1-(5-hydroxyhexyl)-7-propylxanthine (PPFOH), PPFOH was synthesized and identified by gas chromatography/mass spectroscopy (GC/MS) and $^1H$-nuclear magnetic resonance spectroscopy. The molecular weight of synthesized metabolite is 308 dalton. The PPF and PPFOH in plasma were extracted with diethyl ether and identified by electron impact GC/MS. The plasma concentrations of PPF and PPFOH were determined by gas chromatography/nitrogen phosphorus detector in plasma and their pharmacokinetic parameters were determined. The mean half-life of PPF was 0.74 hr. The areas under the curve (AUCs) of PPF and PPFOH were 508 and 460ng.hr/ml, respectively. $C_{max}$ of PPF was about 828.4ng/ml and the peak concentration was achieved at about 2.2 hr ($T_{max}$). These results indicate that PPF is rapidly disappeared from blood due to extensive metabolism into PPFOH.

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Evaluation of Classifiers Performance for Areal Features Matching (면 객체 매칭을 위한 판별모델의 성능 평가)

  • Kim, Jiyoung;Kim, Jung Ok;Yu, Kiyun;Huh, Yong
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.31 no.1
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    • pp.49-55
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    • 2013
  • In this paper, we proposed a good classifier to match different spatial data sets by applying evaluation of classifiers performance in data mining and biometrics. For this, we calculated distances between a pair of candidate features for matching criteria, and normalized the distances by Min-Max method and Tanh (TH) method. We defined classifiers that shape similarity is derived from fusion of these similarities by CRiteria Importance Through Intercriteria correlation (CRITIC) method, Matcher Weighting method and Simple Sum (SS) method. As results of evaluation of classifiers performance by Precision-Recall (PR) curve and area under the PR curve (AUC-PR), we confirmed that value of AUC-PR in a classifier of TH normalization and SS method is 0.893 and the value is the highest. Therefore, to match different spatial data sets, we thought that it is appropriate to a classifier that distances of matching criteria are normalized by TH method and shape similarity is calculated by SS method.

Investigating an Automatic Method for Summarizing and Presenting a Video Speech Using Acoustic Features (음향학적 자질을 활용한 비디오 스피치 요약의 자동 추출과 표현에 관한 연구)

  • Kim, Hyun-Hee
    • Journal of the Korean Society for information Management
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    • v.29 no.4
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    • pp.191-208
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    • 2012
  • Two fundamental aspects of speech summary generation are the extraction of key speech content and the style of presentation of the extracted speech synopses. We first investigated whether acoustic features (speaking rate, pitch pattern, and intensity) are equally important and, if not, which one can be effectively modeled to compute the significance of segments for lecture summarization. As a result, we found that the intensity (that is, difference between max DB and min DB) is the most efficient factor for speech summarization. We evaluated the intensity-based method of using the difference between max-DB and min-DB by comparing it to the keyword-based method in terms of which method produces better speech summaries and of how similar weight values assigned to segments by two methods are. Then, we investigated the way to present speech summaries to the viewers. As such, for speech summarization, we suggested how to extract key segments from a speech video efficiently using acoustic features and then present the extracted segments to the viewers.

Variation of Sink Components in Response to Removal Time of Upper Leaf on Main Stem in Soybean (주경 상부엽 제거시기가 콩의 절위별 Sink형질 변이에 미치는 영향)

  • 박춘봉;이중호
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.40 no.1
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    • pp.16-25
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    • 1995
  • The effects of leaf removal time on variation of nodal sink components in determinated soybean [Glycine max (L.) Merr.] cultivar 'Danyeobkong' were measured at the experiment field of Chonbuk Provincial Rural Development Administration in 1991. Node order in this experiment was calculated from terminal node to bottom node to clarify the photosynthetic ability of canopy leaves. The upper 5 leaves from terminal node of main stem were removed at 5, 15, 25, 35 and 45 days after flowering(DAF) respectively. In spite of light-receiving increment in lower part of main stem and in branch by removing the upper part leaves of main stem, seed weight of that part was not increased in leaf removal treatment compared with control block. The node position reducing pod went down from terminal to bottom by delaying leaf removal time, and the influence of pod number reduction was bigger in DAF 25 than in DAF 15. But the seed number reduction per pod was the biggest in DAF 35. Cracked seed coat ratio ranged from 25% to 35% in control block, while that of leaf removal block had mostly 10% gap compared with the control block.rol block.

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Material properties and clinical application of zirconia-reinforced lithium silicate ceramics (지르코니아 강화 리튬 실리케이트 세라믹의 특성과 임상적용)

  • Kim, Jong-Eun;Kim, Jee-Hwan;Shim, June-Sung;Park, Young-Bum
    • The Journal of the Korean dental association
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    • v.56 no.3
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    • pp.159-166
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    • 2018
  • The zirconia-reinforced lithium silicate ceramic material is a material in which lithium silicate glass contains about 10% by weight of zirconia oxide (zirconia oxide). This material has both the advantages of glass ceramics and zirconia, and it is attracting attention as a CADCAM material for single tooth restoration. ZLS materials have improved strength compared to widely used e.max (lithium disilicate ceramic) materials. It can be used for single crown restoration and ensuring a thickness of 1.5 mm is very important for reliable treatment. In the case of Celtra Duo, heat treatment may be helpful in terms of strength and abrasion resistance. Hydrofluoric acid treatment is helpful for bonding and hydrofluoric acid for a short time may not help to improve the bonding strength. Although zirconia-reinforced lithium silicate ceramic materials have been continuously conducted and published in the laboratory, reliable clinical studies are still lacking. Additional clinical studies will be a very important part of establishing a scientific basis.

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