• Journal of Pharmacopuncture
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• v.25 no.2
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• pp.71-78
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• 2022

Objectives: Post-term pregnancy is a condition associated with increased maternal and fetal complications. Administration of castor oil causes cervical stimulation by increasing the production of prostaglandins. We examined the effects of castor oil on cervical ripening and labor induction through a systematic review and meta-analysis. Methods: The search process was performed to obtain relevant articles from databases including Pubmed, Cochrane library, Scopus, Science direct, SID, Iran Medex, and Google Scholar using the English keywords of cervical ripening, post-term, castor oil, labor induction, Bishop score, and pregnancy considering all possible combinations without time constraints and their Persian equivalents from national databases. Results: A total of eight related articles from the 19 primary studies were extracted and systematically reviewed. According to a cumulative chart, the difference in the post-intervention Bishop score was statistically significant (standard mean difference [SMD]: 1.64, 95% confidence interval [CI]: 1.67-2.11, p = 0.001), indicating an effect of castor oil on increasing the Bishop score. In addition, the difference in labor induction was statistically significant after the intervention (odds ratio: 11.67, 95% CI: 3.34-40.81, p = 0.001), indicating an effect of castor oil on increasing the odds ratio of labor induction (experience of vaginal delivery). Conclusion: This meta-analysis showed that oral administration of castor oil is effective for cervical ripening and labor induction. Midwives should closely monitor pregnant women with prolonged labor and collaborate with obstetricians to employ castor oil as a safe intervention to induce cervical ripening and labor to prevent undue caesarean surgery.

• Korean Parent-Child Health Journal
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• v.21 no.1
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• pp.20-27
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• 2018

Purpose: The purpose of this study was to review the literature on paternity leave and family health over the last 10 years. Methods: Nine studies that met the criteria were selected from sixty-four studies. General characteristics, study design, and major findings about paternity leave were analyzed using an established analysis framework. Results: From the integrative review, paternity leave was found to affect the health of fathers, mothers, and children, as well as family health and gender equality. The father's paternity leave resulted in an increase in mothers' breast feeding rate, a decrease in maternal depression, a reduction in parenting stress, a reduction in all-cause mortality of men, feelings of instinctive paternal love, increased parenting, skills, and positive parent-child relationships. It was interpreted that paternity leave had a positive effect on the mental and physical health of individual members of the family. Conclusion: This study provides the basic data on the health effects of father's parental leave on the family system in a holistic view. In addition, this study proposes the direction of paternity leave and family health research and policy needs.

• Journal of Preventive Medicine and Public Health
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• v.13 no.1
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• pp.67-75
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• 1980

Natural increase rate in population is reached to 1.7% in 1975 fron 2.5% in 1966 because of the effect of Govermental Family Planning Program. The average number of present children and ideal children is just the same, 2.4 people, in this investigation. So, I assume that the number of present and ideal children is approaching each other. The rate of unmarried female workers who don't know even one thing about the know ledge of contraception was 23.9%, and especially that of rural women was 31.5% and 41.3% of them has never experienced contraception. 'Boy-preference' presented 60.1% of unmarried female workers and 79.1% of married women. 'Connection of a family line' related to 'Transfer to next generation of a family line' presented 38.0% and 'Trustworthiness' related to 'Leadership of a family' presented 26.0% (total 64.0%). As this point, Ive can find that this rate reveals the traditional sense of patriarchal system in society and family. The rate of women of experienced artificial abortion has been 52.1% and that of women using it as birth control caused by 'Many children' and 'Short brith-interval' 46.6% of women of experienced pregnancy. So, we can see that artificial abortion is a main cause of Maternal Health destruction.

• Toxicological Research
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• v.11 no.1
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• pp.91-101
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• 1995

A perinatal and postnatal study of KTC-1, a new semisyntheitic rifamycin antituberculous drug, was conducted in Sprague-Dawley rats. Dosages of KTC-1 0, 12, 27.6, and 63.5 mg/kg/day were administered to dams orally by gavage from day 17 of gestation to day 21 of lactation. All pregnant rats were allowed to deliver naturally for postnatal examination of their offspring. At 63.5 mg/kg/day, weakness, dark-red discharge around eyes, a loss in body weight, and a decrease in food and water consumption were observed in dams. An increase in the weight of adrenal gland and spleen, and a decrease in the weight of kidney and heart were also found. An increase in neonatal deaths during the lactation period, a loss in body weight, a delay in physical development, a decrease in traction ability, an increase in the number of errors and the time required for the multiple T-maze trial were found in F1 offspring. In addition, an increase in the incidence of visceral variations and retarded ossification were observed in F1 4 day old rats. An increase in the incience of skeletal anomalies was seen in F2 fetuses. There were no sings of maternal toxicity or embryotoxicity at 12 and 27.6 mg/kg/day. From the results mentioned above, it can be concluded that the no-effect dose levels(NOELs)for dams, F1 offspring, and F2 fetuses are 27.6 mg/kg/day.

• Toxicological Research
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• v.11 no.1
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• pp.81-89
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• 1995

A teratogenicity study of KTC-1, a new semisynthetic rifamycin antituberculous drug, was conducted in Sprague-Dawley rats. Dosages of KTC-1 0, 7, 21, and 63 mg/kg/day were administered to darns orally gayage from day 7 to day 17 of gestation. Two-third of dams per group were subjected to cesarean section on day 21 of pregnancy for examination of their fetuses, and the remaining one-third of darns per group were allowed to deliver naturally for postnatal examination of their offspring. At 21 mg/kg/day, an increase in the skeletal variations of F1 fetuses and a decrease in the body weight of F1 offspring were seen. At 63 mg/kg/day, a loss in body weight was observed in darns. An increase in fetal death rate, a decrease in litter size and body weight, and an increase in the incidence of visceral malforrnations and skeletal variations were found in F1 fetuses. In particular, lumar rib occurred at an incidence of 31%. In addition, an increase in the dead newborns at birth and neonatal deaths during the lactation period, a loss in body weight, and a decrease in spleen weight were observed in F1 offspring. There were no signs of maternal toxicity or embryotoxicity at 7 mg/kg/day. The results suggest that the no-effect dose level(NOEL)for dams is 21 mg/kg/day, and NOELs for F1 fetuses and offspring are 7 mg/kg/day.

• Journal of Nutrition and Health
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• v.17 no.3
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• pp.199-209
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• 1984

Pregnant rats were fed a pyridoxine deficient diet during the gestation and lactation. DEF I group received the deficient diet from delivery ; DEF II group, from the 15 th day of gestation. Body and brain weights, brain protein, DNA, RNA, plasma GOT and GPT, and catecholamines were measured. Effect of MAO inhibiting drug, pargyline, was determined. Brain protein, DNA, and RNA of offsprings of deficient groups were significantly lower than the control group, but RNA/ DNA, brain weight/DNA, and protein/DNA show that cell number were more affected than cell size by the pyridoxine deficiency during the 3rd week of gestation and lactation. Plasma GOT activities were more significantly different than plasma GPT between the control and deficient group. Brain norepinephrine of offsprings of deficient group were significantly lower than the control, but brain dopamine content was not significantly different from the control. At 2nd and 3rd week, norepinephrine was significantly depressed in deficient groups. Pargyline treatment affected a 1.2 fold increase in catecholamines in 3hr while the control had a 1.5 fold increase. Thus norepinephrine and dopamine synthesis was depressed in the deficient groups. Dopaminergic neurons may be less dependent on pyridoxine level than neurons from norepinephrine. Pyridoxine deficiency in maternal diet is not so critical to brain catecholamines of offspring except to the neonatal rats.

• Korean Journal of Community Nutrition
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• v.5 no.1
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• pp.120-129
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• 2000

Very little is known about the relation between isoflavone intake and menopausal symptoms in Korean woman To find the effects and correlations between these factors, questionnaires(maternal factors, menopausal symptoms) anthropometric measurement, 24hr dietary recalls, and urinary isoflavones analysis were conducted in 100 postmenopausal women residing in the Kyunggi-do rural area. The average age hight and weight of the subject were 61.5 years, 153.6 cm and 56.2kg. The average age at menarche, menopause, and menstrual cycle were 16.7 years, 47.2 years, 29.8 years, respectively. Most of the postmenopausal women experienced mildly menopausal symptoms. The mean calorie, protein and calcium intake were 1417.6 kcal(74.7% of the Korean RDA) 53.2 g(88.6% of the Korean RDA) and 454.0mg(65.6% of the Korean RDA) respectively. The ration of energy from carbohydrate, protein, and fat was 68: 15: 17 The average isoflavone intake from soy foods was 27.27 mg. The major food source of the isoflavone were soybeans and soybean curd. The average urinary isoflavone excretion was 2. 78nmol/mg Cr and showed significant positive correlation with isoflavone intake. Isoflavone intake from soy foods had a negative correlation with the severity of menopausal symptoms. Therefore, soy foods which contain isoflavone may have a protective effect on menopausal symptoms of women in Korea.

• Women's Health Nursing
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• v.19 no.3
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• pp.153-165
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• 2013

Purpose: The purpose of this study was to review the literature on intervention for breast cancer survivors and their partners. Methods: The literature search was performed using MEDLINE, Pubmed, and Proquest to summarize the current state of knowledge regarding intervention for breast cancer survivors and their partners. Articles published between January 2000 and December 2011 were included. Results: A total of 14 studies were identified. Couple-base d intervention was more effective than intervention for survivors alone. Intervention to partners had also effects on their wives. Most studies were conducted in USA with Caucasian women. Sample size of intervention studies was small with most being pilot studies. Conclusion: Providing couple-based intervention to breast cancer survivors could have positive impacts on physical, interpersonal, and social aspects in breast cancer survivors. Future studies with large sample and different ethnicity are needed to confirm the effects of couple-based interventions for breast cancer survivors.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.sup1
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• pp.1-6
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• 2008

Previous infant feeding guidelines recommended a delayed introduction of solids to beyond 6 months of age to prevent atopic diseases. However, scientific evidence supporting a delayed introduction of solids for prevention of atopic diseases is scarce and inconsistent. Current evidence does not support a major role for maternal dietary restrictions during pregnancy or lactation in the prevention of atopic disease. In studies of infants at high risk of developing atopic disease, there is evidence that exclusive breastfeeding for at least 4 months compared with feeding intact cow milk protein decreases the incidence of atopic dermatitis, cow milk allergy, and wheezing in early childhood. For infants at high risk of developing atopic disease who are not breastfed exclusively for 4 to 6 months, there is modest evidence that atopic dermatitis may be delayed or prevented by the use of extensively or partially hydrolyzed formulas, compared with cow milk formula, in early childhood. There is no convincing evidence that a delayed introduction of solid foods beyond 4 to 6 months of age prevents the development of atopic disease. For infants after 4 to 6 months of age, there are insufficient data to support a protective effect of any dietary intervention for the development of atopic disease.

• Journal of environmental and Sanitary engineering
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• v.21 no.2 s.60
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• pp.36-46
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• 2006

The purpose if this study was to investigate mother' oral health management behavior to their children. Two hundreds sixty seven mothers with elementary school students were surveyed among the residents living of Iksan city, Korea. A questionnaire was constructed and administered to the samples. The research focused in the following items: the subjects' socio-demographic factors such as education level and employment and so on; their knowledge of plaque; the leading causes of caries, regular dental examinations; dental treatment; their interest in their children's dental health; the frequency of the subjects examining their children's teeth; non-cariogenic food preparation, etc. Being based in collected data, mothers' oral health management behavior to their children were analyzed according to maternal socio-demographic factor and result were following. There was a difference in the subjects knowledge of dental plaque in accordance with their employment or unemployment and family income. There was no difference in mother's oral health management behavior to their children according to parents' education level, the subjects' age and family income. Most of mother answered the main reason of dental caries was that their children did not toothbrush their teeth regularly and there was a difference in the understanding of the subjects in accordance with the education level of fathers and family income. The subjects had a low understanding of the effect of preventing caries with the help of fluoride. They didn't have enough understanding of water fluoridation. So it is necessary that active campaigns should be launched to enlighten people in relation to the ways of preventing dental caries with fluoride.