• Proceedings of KHEA Conference
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• 1997.07a
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• pp.59-59
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• 1997

• Journal of Ginseng Research
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• v.46 no.1
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• pp.62-70
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• 2022

Background: Maternal Toxoplasma gondii (T. gondii) infection during pregnancy has been associated with various mental illnesses in the offspring. Ginsenoside Rh2 (GRh2) is a major bioactive compound obtained from ginseng that has an anti-T. gondii effect and attenuates microglial activation through toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling pathway. GRh2 also alleviated tumor-associated or lipopolysaccharide-induced depression. However, the effects and potential mechanisms of GRh2 on depression-like behavior in mouse offspring caused by maternal T. gondii infection during pregnancy have not been investigated. Methods: We examined GRh2 effects on the depression-like behavior in mouse offspring, caused by maternal T. gondii infection during pregnancy, by measuring depression-like behaviors and assaying parameters at the neuronal and molecular level. Results: We showed that GRh2 significantly improved behavioral measures: sucrose consumption, forced swim time and tail suspended immobility time of their offspring. These corresponded with increased tissue concentrations of 5-hydroxytryptamine and dopamine, and attenuated indoleamine 2,3-dioxygenase or enhanced tyrosine hydroxylase expression in the prefrontal cortex. GRh2 ameliorated neuronal damage in the prefrontal cortex. Molecular docking results revealed that GRh2 binds strongly to both TLR4 and high mobility group box 1 (HMGB1). Conclusion: This study demonstrated that GRh2 ameliorated the depression-like behavior in mouse offspring of maternal T. gondii infection during pregnancy by attenuating the excessive activation of microglia and neuroinflammation through the HMGB1/TLR4/NF-κB signaling pathway. It suggests that GRh2 could be considered a potential therapy in preventing and treating psychiatric disorders in the offspring mice of mothers with prenatal exposure to T. gondii infection.

• Korean Journal of Child Studies
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• v.38 no.1
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• pp.251-262
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• 2017

Objective: This study analyzed mother-child interactions in a stressful situation each second by mother's emotional regulation level. Methods: The study was conducted with 16 mothers and their 5-year-old children playing a teaching task for 15 min. During the interactions, the participants were videotaped and examined. Furthermore, qualitative analysis was used for analyzing mother-child interactions in detail by creating a situation that maximizes the stress and frustration of the mother and child. Results: The results showed that maternal humor and affection were significantly related to child positive emotion and that maternal coaching closely correlated with the child pride, pleasure, and whining. Additionally, maternal intrusive behavior showed a positive correlation with child anger. Lastly, mothers with higher levels of emotional regulation more often expressed affection to their children. They were more actively involved in the tasks and used fewer positive or negative directive expressions. Therefore, children of this group expressed more positive emotions. Conclusion: These findings suggests that programs improving parental emotional reaction and emotion regulation should be developed.

• Journal of Korean Academy of Nursing
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• v.35 no.2
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• pp.419-427
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• 2005

Purpose: The purpose of this study was to identify the effects of a workbook program on percieved stress levels, maternal role confidence and breastfeeding practices of mothers of premature infants. Method: This study employed a quasi-experimental non-equivalent pre-and-post test to compare the two groups. Data was collected from 32 subjects from March 10. to September 5, 2003 at an NICU located in S. city. In the sample, fifteen mothers were in the experimental group and seventeen were in the control group. A workbook program was provided twice during a period from two-three days after the baby's admission to one week after the first intervention. The instruments used were the PSS and self confidence scale. Data was analyzed by means of frequency, SD, $x^2-test$, Fisher's exact test, Mann-Whitney test, and the Wilcoxon signed rank test. Result: There was a significant difference in perceived stress levels between the experimental and control group (U=2.366, p=.018). There was not a significant difference in maternal role confidence between the two groups (U=1.002, p=.316). There was a significant difference in breastfeeding practice between the two groups ($x^2=4.910$, p=.035). Conclusion: It is concluded that a program using a workbook has a positive effect on decreasing the perceived stress level and increasing breastfeeding practice.

• The Korean Journal of Community Living Science
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• v.25 no.2
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• pp.131-145
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• 2014

This study examines the effects of maternal behaviors and children's self-control ability on their subjective well-being. Data were collected from 416 fifth- and sixth-graders residing in Kwangju, Korea. Cronbach's ${\alpha}$ and the hierarchical regression analysis method were employed for a statistical analysis. According to the results of the hierarchical multiple regression analysis, children's self-control ability best explained their subjective well-being. For individual factors, motivational self-control had the greatest effect on subjective well-being, followed by behavioral self-control, cognitive self-control, the level of income, gender, and the employment status, in that order. The results for effects of maternal behaviors and children's self-control ability on children's subjective well-being highlight. The important roles played by the mother and the child's self-control ability in improving the child's subjective well-being. The study contributes to the literature by providing fundamental insights into children's higher quality of life.

• Korean Journal of Child Studies
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• v.36 no.1
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• pp.163-185
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• 2015

This study examined the influences of general characteristics, maternal parenting behaviors and children's self-control ability on children's social competence. A total of 416 children in the fifth and sixth grades responded to questionnaires, which included items related to their social competence, their mothers' parenting behavior, as well as their own self-control ability. Data were analyzed by means of Pearson correlation analysis and the hierarchical regression analysis method. According to the results of the hierarchical multiple regression analysis, children's self-control ability best explained their social competence. In terms of individual factors, motivational self-control had the greatest effect on social competence, followed by cognitive self-regulation, behavioral self-regulation, economic level, gender and grades, in that order. The results for the effects of maternal parenting behaviors and children's self-control ability on children's social competence highlighted the important roles played by the mother and the child's self-control ability in improving the child's social competence. The study contributes to the literature by providing fundamental insights into children's higher quality of life.

• Korean Parent-Child Health Journal
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• v.6 no.2
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• pp.103-114
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• 2003

This descriptive study was conducted to explore the mothers' perceived temperament of their preschoolers, and its related factors. Survey from 212 mothers of preschoolers residing in Seoul, Daejeon, and Suwon was performed, and Schaefer's MBRI(Maternal Behavior Research Instrument), and PTQ(Parent Temperament Questionnaire) by Thomas and Chess, Child-rearing burden instrument by Han were used to collect data from September 15 to October 31, 2002. Data was analyzed with SPSS 10.0 Win program. Summaries of results were as follows: 1. There was no significant difference in temperament type-easy or difficult child-depending upon the demographic characteristics. 2. In temperament subscale, boys showed higher activity level than girls, and in working mothers group, adaptability was significantly lower although mood was higher. Preschoolers with expanded families were higher in activity level and intensity of reaction than with nuclear families. 3. Approach-withdrawal, adaptability, and mood showed significant negative relationship with maternal childrearing burden. 4. Temperament showed significant positive or negative relationship with maternal childrearing attitudes. In conclusion, it determined preschoolers' temperament was affected by primary environment such as maternal attitude, childrearing burden, and family type as well as children's gender. It was suggested that parent education and counselling program in nursing would be needed to promote children's desirable temperament.

• Korean Journal of Human Ecology
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• v.21 no.6
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• pp.1029-1042
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• 2012

The purpose of this study was to explore relationships between preschooler's aggression and social skills, maternal management strategies of peer relations and parenting behaviors and preschoolers' internet-game addictive inclination. Participants included seventy-seven (77) 5 to 6-year-old preschoolers (44 boys, 33 girls) and their mothers. The Aggressive Behavior Scale (Lee & Choi, 2001), the Social Skill Rating Scale (Suh, 2004), the Maternal Parenting Behaviors Scale (Rhu & Lee, 2007) and the Parental Involvement Checklist (Park, 2001) were used in this study. The Internet Game Addiction Scale (Korea Agency for Digital Opportunity and Promotion, 2006) was used to identify higher and lower addictive level of internet-game inclination. Collected data were analyzed by descriptive statistics and t-test. Major findings revealed that preschooler's social skills, maternal management strategies of peer relations and parenting behaviors showed a predictable correlation to preschooler's internet-game addictive inclination.

• Journal of Korean Academy of Nursing
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• v.26 no.2
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• pp.443-466
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• 1996

Young children need continuous care and fostering by their family. They help children organize and develop their potential and grow to be and integrated individuals. Children are influenced by then family at first and continuously when they grow up and develop their capability. Especially, mothers spend a lot of time with time to their children, encourage children's growth, give advice, and do their best to take care of their children. The ethnographic study is to understand the patterns and rules of human behaviors. This study utilized this method in order to interpret the maternal health promoting behaviors for their children. The data were collected through the participant observation and direct interview for about 18 months in P city. The participants were 7 mothers, from 32 to 37 years old. They have children of ages 3 to 10 and 1 or 2 children in total. The data were analyzed through the Spradley's Ethnographic method and the results were summarized as follows : The viewpoints which influence maternal health promoting behaviors include “having childlike appearance”. “having childlike character”, “living without illness”, and “eating well”. The maternal health promoting behaviors for children are classified as “adapting to nature”, “supporting of ability”, “sharing with the family”, “training”, and “praying”. The adapting behaviors include “recognizing child's innate character”, “controlling maternal desires”, “preparing natural food”, which includes breast feeding. The supporting behaviors include “recognizing childlikeness”, “empowering”, and “restricting certain actions to preventing accidents”. In order to promote child's health, it is essential to promote mother's health first of all. The sharing with the family includes “promoting family concord or acquaintanceships concord” and “adapting to circumstances beyond family”. The training behaviors include “forming good habits” and “having good moral value”. It is very important to form good habits in childhood. The praying behavior include “waiting for opportunities” and “endeavoring activity to promote child's health”. The above 5 behaviors by mothers appeared to be able to promote children's health. The results of this study can be utilized to provide the basic information necessary to develop the patterns of maternal health promoting behaviors consistent with our culture and can contribute us develop the body of knowledge about the maternal health promotion for children in nursing.

• Korean Journal of Community Nutrition
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• v.3 no.1
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• pp.3-11
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• 1998

This study was aimed to evaluate any influence of environmental factors associated with feeding on infants' growth. One hundred infants(62 males and 38 females) aged 4-9 months were measured for length and were weighed. Their mothers were interviewed using questionnaires including general and environmental characteristics and maternal feeding attitude, ideal body habitus, infant's food behavior, and infant's food behavior, and infant's temperament. A further study was conducted on 29 infants at the time their ages reached 12 months. Their dietary intakes were assessed, and blood hemoglobin and serum ferritin concentrations were measured. Z-scores of weight-for-age(WAZ) and Z-scores of height-for-age(HAZ) of 4-9 month- old infants were not correlated with age, education level, income, weight, and height of their parents. Formula-fed infants had significantly lower WAZ and body mass index (BMI) than those of breast fed infants. WAZ was significantly correlated with maternal feeding attitude, but not with ideal body habitus, infant's food behavior or infant's temperament. WAZ of 12-months after birth because of supplementary foods introduced from 6 months of age. WAZ and BMI were positively correlated with blood hemoglobin concentration. Therefore, to ensure proper growth of infants, efforts should be given to postental factors such as breast-feeding, maternal feeding attitude, adequate iron status as well as prenatal factors. (Korean J Community Nutrition 3(1) : 3∼11, 1998)