• Microbiology and Biotechnology Letters
• /
• v.20 no.5
• /
• pp.597-606
• /
• 1992

Effects of dilution rate, inlet glucose and ammonium chloride concentrations on ,he performance of continuous culture of Alcaligenes eutrQPhus for poly-p-hydroxybutyrate (PHB) production were investigated. When inlet substrate concentrations were maintained constant (inlet glucose concentration = 20 g/l, inlet ammonium chloride concentration = 2 g/l), growth rate of residual biomass and PHB production rate showed its maximum at $0.1h^{-1}$ and $0.06h^{-1}$, respectively, and washout at $0.13h^{-1}$. PHB content decreased from 50% to 25% by increasing dilution rate, while specific PHB production rate increased continuously. Cell mass and PHB concentration gave its maximum values at inlet ammonium chloride concentration of 2 g/l and thereafter decreased, which showed the existence of substrate inhibition by ammonium. When inlet glucose concentration was 30 g/l, cell mass reached its maximum value, while PHB concentration increased continuously. The parameters of kinetic model were evaluated by the graphical and parameter estimation methods. The computer simulation results for the effects of dilution rate, inlet glucose and ammonium chloride concentrations fitted the experimental data very well.

• Geomechanics and Engineering
• /
• v.24 no.4
• /
• pp.323-335
• /
• 2021

This paper aims to estimate the range of the excavation damaged zone (EDZ) formation caused by the tunnel boring machine (TBM) advancement through dynamic three-dimensional large deformation finite element analysis. Large deformation analysis based on Coupled Eulerian-Lagrangian (CEL) analysis is used to accurately simulate the behavior during TBM excavation. The analysis model is verified based on numerous test results reported in the literature. The range of the formed EDZ will be suggested as a boundary under various conditions - different tunnel diameter, tunnel depth, and rock type. Moreover, evaluation of the integrity of the tunnel structure during excavation has been carried out. Based on the numerical results, the apparent boundary of the EDZ is shown to within the range of 0.7D (D: tunnel diameter) around the excavation surface. Through series of numerical computation, it is clear that for the rock of with higher rock mass rating (RMR) grade (close to 1st grade), the EDZ around the tunnel tends to increase. The size of the EDZ is found to be direct proportional to the tunnel diameter, whereas the depth of the tunnel is inversely proportional to the magnitude of the EDZ. However, the relationship between the formation of the EDZ and the stability of the tunnel was not found to be consistent. In case where the TBM excavation is carried out in hard rock or rock under high confinement (excavation under greater depth), large range of the EDZ may be formed, but less strain occurs along the excavation surface during excavation and is found to be more stable.

• The Korean Journal of Pain
• /
• v.36 no.2
• /
• pp.184-194
• /
• 2023

Background: Degenerative lumbar spondylolisthesis (DLS) is frequently associated with lumbar spinal stenosis (LSS) and conservative treatments such as epidural steroid injection do not have long-term benefits in LSS patients with DLS. This study evaluated the effectiveness of percutaneous epidural neuroplasty using a balloon catheter in patients with LSS and DLS. Methods: Patients' sex, age, body mass index, diabetes, hypertension, stenosis grading, pain duration, location, pain intensity, and medications were retrieved from electronic medical records. At 1, 3, and 6 months following the procedure, data on pain severity, medication usage, and physical functional status were analyzed. A generalized estimating equations model was used at the six-month follow-up. Patients were divided into those with DLS (the spondylolisthesis group) and those without DLS (the no spondylolisthesis group) to evaluate whether the effects of percutaneous epidural neuroplasty using a balloon catheter were different. Results: A total of 826 patients were included (spondylolisthesis: 433 patients, 52.4%; no spondylolisthesis: 393 patients, 47.6%). Age, body mass index, hypertension, pain location, and stenosis grading were statistically different between the two groups. The generalized estimating equations analyses with unadjusted and adjusted estimation revealed a significant improvement in the estimated mean numerical rating scale of pain intensities compared to that at baseline in both groups (P < 0.001). Any adverse events that occurred were minor and temporary. Conclusions: Percutaneous epidural neuroplasty using a balloon catheter may be an alternative treatment option for patients with chronic LSS, regardless of accompanying DLS, who have had failed conservative management.

• The Journal of Engineering Geology
• /
• v.10 no.1
• /
• pp.13-25
• /
• 2000

A three-dimensional discrete fracture network model based on probabilistic characteristics of fracture geometry and transmissivity was designed to calculate the conductivity tensor and to estimate theanisotropy of conductivity. The conductivities, $K_p$, obtained from the numerical simulation of single-holepacker test corresponded well to those from the field tests. From this, it can be concluded that thefracture network model designed in this study can represent hydraulic characteristics of in-situ fractured rock mass. Block-scale conductivities, $K_b$, estimated from the modelling of steady-state flow through the REV-scale block were ranged between the arithmetic mean and harmonic mean of theconductivity estimates from packer tests. The conductivity along north-south direction was 1.4 timesgreater than that along the east-west direction. It was concluded that the anisotropy of conductivitywas insignificant. It was also found that there was a little correlation between $K_b$ and $K_p$. This would be to that the conductivities from the packer test simulation was strongly dependent on thetransmissivity and the number of fractures within the packer test intervals.

• Tunnel and Underground Space
• /
• v.27 no.2
• /
• pp.109-119
• /
• 2017

A lot of twin tunnels were modelled with different pillar widths, rock mass classes and stress ratios in order to consider various site conditions, and the stabilities of the pillars were estimated by numerical analyses and scaled model tests. The strength-stress ratios of the pillar were obtained from three different methods which were using the stresses appeared at the middle point, the whole average and the left/right edges of the pillar. The strength-stress ratio of the pillar edges showed relatively conservative values among them, and it was also practically consistent with the tunnel excavating steps comprising the construction sequence analyses which included the partial excavation and the support system. Scaled model tests were also performed to investigate the tunnel stability, where it was found that cracks were progressively generated from the pillar edges toward the middle point of the pillar. Therefore, in order to both prevent the local damage of pillar and conservatively estimate the tunnel stability, it was thought to be an appropriate method using the strength-stress ratio obtained from the left/right edges of the pillar.

• Atmosphere
• /
• v.24 no.2
• /
• pp.245-251
• /
• 2014

Statistical trajectory analysis has been widely used to identify potential source regions for chemically and radiatively important chemical species in the atmosphere. The most widely used method is a statistical source-receptor model developed by Stohl (1996), of which the underlying principle is that elevated concentrations at an observation site are proportionally related to both the average concentrations on a specific grid cell where the observed air mass has been passing over and the residence time staying over that grid cell. Thus, the method can compute a residence-time-weighted mean concentration for each grid cell by superimposing the back trajectory domain on the grid matrix. The concentration on a grid cell could be used as a proxy for potential source strength of corresponding species. This technical note describes the statistical trajectory approach and introduces its application to estimate potential source regions of $CO_2$ enhancements observed at Korean Global Atmosphere Watch Observatory in Anmyeon-do. Back trajectories are calculated using HYSPLIT 4 model based on wind fields provided by NCEP GDAS. The identified $CO_2$ potential source regions responsible for the pollution events observed at Anmyeon-do in 2010 were mainly Beijing area and the Northern China where Haerbin, Shenyang and Changchun mega cities are located. This is consistent with bottom-up emission information. In spite of inherent uncertainties of this method in estimating sharp spatial gradients within the vicinity of the emission hot spots, this study suggests that the statistical trajectory analysis can be a useful tool for identifying anthropogenic potential source regions for major GHGs.

• Advances in environmental research
• /
• v.9 no.2
• /
• pp.97-107
• /
• 2020

The indiscriminate growth in global population poses a threat to the world in handling and disposal of Municipal solid waste. Rapid urban growth increases the production, consumption and generation of Municipal solid waste which leads to a drastic change in the environment. The methane produced from the Municipal Solid waste accounts for up to 11% global anthropogenic emissions, which is a major cause for global warming. This study reports the methane emission estimation using IPCC default, TNO, LandGEM, EPER and close flux chamber from open dump yards at Perungudi and Kodungaiyur in Chennai, India. The result reveals that the methane emission using close flux chamber was in the range of 8.8 Gg/yr-11.3 Gg/yr and 6.1Gg/yr to 9.1 Gg/yr at Kodungaiyur and Perungudi dump yard respectively. The per capita waste generation was estimated based on waste generation and population. The waste generation potential was projected using linear regression model for the period 2017-2050. The trend of CH₄ emission in the actual field measurement were increased every year, similarly the emission trend also increased in IPCC default method (mass balance approach), EPER Germany (zero order decay model) where as TNO and Land GEM (first order decay model) were decreased. The present study reveals that Kodungaiyur dump yard is more vulnerable to methane emission compared to Perungudi dump yard and has more potential in waste to energy conversion mechanisms than compare to Perungudi dump yard.

• Journal of Convergence for Information Technology
• /
• v.11 no.10
• /
• pp.36-44
• /
• 2021

Estimation on SW Sizing applied to fintech is very difficult, a task requiring long time, it is difficult for client companies and developer companies to accurately calculate the size of software development. The size is generally estimated based on the experience of project managers and the general functional scoring method. In this paper, propose a model that can be applied to fintech development projects by quantitatively calculating the required functions from the user's point of view, measuring the scale, and calculating the scale in real time. Through the proposed model, the amount of work can be estimated prior to development and the size can be measured, and the M/M and the estimated quotation amount can be calculated based on the program list by each layer. In future studies, by securing size computation data on existing the Fintech Project in mass, research on accurate size computation would be required.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2010.10a
• /
• pp.491-496
• /
• 2010

The direct design modification of problematic component is disallowed in order to sacrifice other major factors such as a stability or a major performance. So, the best design policy is to risvise the immature structural medchanism under the minimal design change as soon as possible. For this paper presents a new design sensitivity analysis based on transmissibility rtio (TR) of response acceleration to find a proper candidate for the minimal design modification. The new sensitivity analysis is based on the fact that the sensitivity of TR over a small design change is inversly proportinal to the magnitude of TR. The theory of proposed design sensitivity analysis is simulated with the variance of TR over a dynamic change. Then, new methodology is appplied for a linear elastic specimen to detect the most sensitive node over a design change using measured accleration data during uni-axial vibration test, The physical verification of the sensitivity method is conducted on the CAE model of a linear elastic specimen by adding concentration mass and the vibration fatigue of the simple specimen is analyzed to estimate the relationship between fatigue behaviors and sensitivity consequences.

• Proceedings of the Korean Environmental Sciences Society Conference
• /
• 2003.05a
• /
• pp.155-160
• /
• 2003

Indoor air quality can be affected by indoor sources, ventilation, decay and outdoor levels. Although technologies exist to measure these factors, direct measurements are often difficult. The purpose of this study was to develop an alternative method to characterize indoor environmental factors by multiple indoor and outdoor measurements. Daily indoor and outdoor $NO_2$ concentrations were measured for 30 consecutive days in 28 houses in Brisbane, Australia, and for 21 consecutive days in 37 houses in Seoul, Korea. Using a mass balance model and regression analysis, penetration factor (ventilation rate divided by the sum of ventilation rate and deposition constant) and source strength factor (source strength divided by the sum of ventilation rate and deposition constant) were calculated using multiple indoor and outdoor measurements. Subsequently, the ventilation rate and $NO_2$ source strength were estimated. Geometric means of ventilation rate were 1.44 ACH in Brisbane, assuming a residential $NO_2$ deposition constant of 1.05 $hr^{-1}$, and 1.36 ACH in Seoul, with the measured residential $NO_2$ deposition constant of 0.94 $hr^{-1}$. Source strengths of $NO_2$ were 15.8 $\pm$ 18.2 ${\mu}g$/$m^3$.hr and 44.7 $\pm$ 38.1${\mu}g$/$m^3$.hr in Brisbane and Seoul, respectively. In conclusion, indoor environmental factors were effectively characterized by this method using multiple indoor and outdoor measurements.