• 제목/요약/키워드: mass balance method

검색결과 237건 처리시간 0.024초

Characterizing a Full Spectrum of Physico-Chemical Properties of Ginsenosides Rb1 and Rg1 to Be Proposed as Standard Reference Materials

  • Kim, Il-Woung;Hong, Hee-Do;Choi, Sang-Yoon;Hwang, Da-Hye;Her, Youl;Kim, Si-Kwan
    • Journal of Ginseng Research
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    • 제35권4호
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    • pp.487-496
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    • 2011
  • Good manufacturing practice (GMP)-based quality control is an integral component of the common technical document, a formal documentation process for applying a marketing authorization holder to those countries where ginseng is classified as a medicine. In addition, authentication of the physico-chemical properties of ginsenoside reference materials, and qualitative and quantitative batch analytical data based on validated analytical procedures are prerequisites for certifying GMP. Therefore, the aim of this study was to propose an authentication process for isolated ginsenosides $Rb_1$ and $Rg_1$ as reference materials (RM) and for these compounds to be designated as RMs for ginseng preparations throughout the world. Ginsenoside $Rb_1$ and $Rg_1$ were isolated by Diaion HP-20 adsorption chromatography, silica gel flash chromatography, recrystallization, and preparative HPLC. HPLC fractions corresponding to those two ginsenosides were recrystallized in appropriate solvents for the analysis of physico-chemical properties. Documentation of the isolated ginsenosides was made according to the method proposed by Gaedcke and Steinhoff. The ginsenosides were subjected to analyses of their general characteristics, identification, purity, content quantitation, and mass balance tests. The isolated ginsenosides were proven to be a single compound when analyzed by three different HPLC systems. Also, the water content was found to be 0.940% for $Rb_1$ and 0.485% for $Rg_1$, meaning that the net mass balance for ginsenoside $Rb_1$ and $Rg_1$ were 99.060% and 99.515%, respectively. From these results, we could assess and propose a full spectrum of physicochemical properties for the ginsenosides $Rb_1$ and $Rg_1$ as standard reference materials for GMP-based quality control.

물질수지를 이용한 학교 실내환경의 포름알데히드(HCHO) 배출량 산정에 의한 실내공기질 개선 평가 (Evaluation of Indoor Air Quality Improvement by Formaldehyde Emission Rate in School Indoor Environment Using Mass Balance)

  • 양원호;손부순;김대원;김영희;변재철;정순원
    • 한국산업보건학회지
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    • 제15권3호
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    • pp.160-165
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    • 2005
  • Schools have significant and serious indoor environmental health problem, of which indoor air quality (IAQ) in school building may affect the health of the students and indirectly affect learning performance. Schools are of special concern when regarding indoor exposure to air pollutants, because students are particularly sensitive to pollutants and spend a significant amount of time in that environment. Therefore researches for improvement of indoor air quality have been developed such as installation of air cleaning device, ventilation system, titanium dioxide(TiO2) coating and so on. However, it is difficult to evaluate the magnitude of improvement of indoor air quality in field study because indoor air quality can be affected by source generation, outdoor air level, ventilation, decay by reaction, temperature, humidity, mixing condition and so on. In this study, evaluation of reduction of formaldehyde emission rate in school indoor environments by far-Infrared ray coating material was carried out using mass balance model in indoor environment. we proposed the evaluation method of magnitude of improvement in indoor air quality, considering outdoor level and ventilation. Since simple indoor concentration measurements could not properly evaluate the indoor air quality, outdoor level and ventilation should be considered when evaluate the indoor air quality.

가축분뇨로부터 질소 회수 연구 현황 및 시사점 분석 (Analysis of the current status and implications of nitrogen recovery from livestock manure)

  • 임성원;김상미;김지민;김동훈
    • 유기물자원화
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    • 제29권1호
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    • pp.37-46
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    • 2021
  • 가축분뇨에 함유된 질소와 인은 환경오염 유발 물질이지만 다양한 산업에서 사용되는 필수 자원이기도 하다. 본 연구에서는 가축분뇨에서 질소 회수에 활용되고 있는 스트리핑, 건조 및 탄화, 이온 교환, 전기투석에 대해 소개하였고, 2011년부터 2020년도까지 국내·외에서 수행한 실규모 연구 현황과 해외 실증플랜트 운영 사례를 분석하였으며 상기 조사결과를 바탕으로 공정별 평가를 실시하였다. 또한, 대표적인 기술인 스트리핑의 주요 운전인자인 pH, 온도, 기액비 등의 적정 범위를 제시하였고, 바이오가스화 공정 연계 시 예상되는 물질수지를 제공하였다. 본 연구에서 제시한 정보는 향후 관련 국내 정책 수립 및 실규모 플랜트 운전 시 유용한 자료로 활용이 가능할 것으로 판단된다.

간헐포기공정과 막결합 간헐포기공정의 오염물질 제거특성 비교 (Comparison of Pollutants Removal between the Intermittently Aerated Bioreactor(IABR) and Intermittently Aerated Membrane Bioreactor(IAMBR))

  • 최창규;이광호
    • 대한토목학회논문집
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    • 제26권1B호
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    • pp.119-124
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    • 2006
  • 본 연구의 목적은 간헐포기공정(IABR)과 막결합 간헐포기공정(IAMBR)의 오염물질 제거능력과 영양염류 제거 mechanism을 비교 검토하여 막침적의 타당성을 확보하고 질산화율 및 탈질율을 산정하였으며, 질소물질수지를 수립하고자 하였다. 그 결과로서 IAMBR과 IABR의 경우 유기물 제거에 있어서는 큰 차이를 보이지 않았으나 영양염류 제거능력은 IAMBR이 IABR에 비해 높게 나타났다. 또한, 무산소 상태에서 반응조 내의 질산성 질소 농도가 IAMBR이 낮게 유지되는 것으로 보아 높은 탈질화 반응이 일어난 것으로 판단되며, 질소물질수지의 결과에서도 IAMBR에서 탈질된 질소성분이 40.9%로 IABR의 10.7%보다 4배 이상 높은 탈질능력을 보였다. 따라서, 높은 MLSS 농도의 유지와 간헐적 유입 유출 방식의 적용이 가능한 장점을 지니고 있는 막이 월등한 질소제거능력의 차를 보임으로써 간헐포기공정에 대한 막결합의 타당성이 충분한 것으로 사료된다.

저항운동과 유산소운동이 여성노인의 보행능력, 체력 및 신체구성에 미치는 효과 (The Effects of Resistance and Aerobic Exercise on Gait Ability, Physical Fitness, and Body Composition in Older Women)

  • 변재철
    • 대한통합의학회지
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    • 제6권3호
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    • pp.103-112
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    • 2018
  • Purpose : The purpose of this study was to determined the effects of resistance and aerobic exercise on gait ability, physical fitness and body compositions in older women. Method : The subjects were 24 older women who were randomly divided into two groups (resistance exercise, n=12, and aerobic exercise, n=12). They 65~80 years old. The subjects done the Gym-ball, Togu, and senior dance exercise three times per week-for 70 minutes each time for 16 weeks. Body compositions, physical fitness, and gait ability were measured in this study. Result : There were significantly improved the walk performance after exercise training for 16 weeks. In particular, it was more effective on resistance exercise training in older women. There were significant differences in muscle endurance, flexibility, balance, body weight, percent of body fat, and body mass index (BMI) after the exercise program. Conclusion : It was more effective improved on muscle endurance, flexibility, and balance performance after resistance exercise program than an aerobic exercise program in older women.

SenSation : A New Translational 2 DOF Haptic Device with Parallel Mechanism

  • Chung, Young-Hoon;Lee, Jae-Won
    • Transactions on Control, Automation and Systems Engineering
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    • 제3권4호
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    • pp.217-222
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    • 2001
  • We propose a new two-degree of freedom parallel mechanism for a haptic device and will refer to the mechanism as the SenSation. The SenSation is designed in order to improve the kinematic performanced and to achieve static balance. We use the panto graph mechanisms in order to change the location of active joints, which leads to transform a direct kinematic singularity into a nonsingularity. The direct kinematic singular configurations of the SenSation occur near the workspace boundary. Using the property that position vector of rigid body rotating about a fixed point is normal to the velocity vector, Jacobian matrix is derived. Using the vector method, two different types of singularities of the SenSation can be identified and we discuss the physical significance of each of the three types of singularities. We will compare the kinematic performances(force manipulability ellipsoid, kinematic isotropy) of the SenSation with those of five-var parallel mechanism. By specifying that the potential energy be fixed, the conditions for the static balancing of the SenSation is derived. The static balancing is accomplished by changing the center of mass of the links.

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노르딕 워킹이 퇴행성 무릎 관절염 노인여성의 근력과 유연성, 균형 및 통증에 미치는 영향 (Effects of Nordic Walking Exercise on muscular strength, Flexibility, Balance and Pain in Older Woman with Knee Osteoarthritis)

  • 오유성;김지선;장우성
    • 한국응용과학기술학회지
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    • 제36권4호
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    • pp.1312-1326
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    • 2019
  • 본 연구는 퇴행성 무릎 관절염을 가진 노인여성을 대상으로 12주간의 노르딕 워킹을 통해 신체 기능과 관절염 통증 정도의 개선에 어떠한 효과를 미치는지 규명하는데 목적이 있다. 본 연구의 대상자는 퇴행성관절염으로 진단받은 노인여성 16명(나이: 73.00±3.70year, 신장: 154.30±4.07cm)을 대상으로 무선배정 된 노르딕 워킹 운동그룹(n=9)과 통제그룹(n=7)으로 나누었다. 운동 그룹은 노르딕 스틱을 이용하여 12주간 주 3회, 1회 30분 노르딕 워킹 운동을 실시하였고, 운동 강도는 HRR의 40-60%로 설정하였다. 통제그룹은 동일한 기간 동안 일상생활을 유지하도록 하였다. 종속변인으로 신체조성(체중, 체지방률, 근골격량)과 근력 과 유연성(상·하지 근력, 상·하지 유연성), 균형능력(정적균형, 동적균형) 및 통증정도를 측정하였다. 이러한 지표들의 측정은 운동프로그램을 진행하기 전과 후로 나누어 2번 측정하였다. 자료처리는 SPSS-PC version 25.0을 이용하여 실험집단과 통계집단간의 생리학적 특성 비교를 위해 독립표본 t-test를 사용하였으며, 노르딕 워킹 운동그룹과 통제그룹의 그룹 간, 시기간의 변화를 알아보기 위해 2×2 반복측정 이원배치분산분석을 사용하였다. 연구 결과는 첫째, 12주간의 노르딕 워킹을 통해 신체조성 기능에서 체지방률은 운동 처치 후에 감소하는 결과가 나타났으며(p=.004), 집단 간과 시기 간의 상호작용에서도 감소하는 결과가 나타났다(p=.003). 골격근량은 운동처치 후에 증가하는 결과가 나타났으며(p=.018), 집단 간과 시기 간의 상호작용에서도 증가하는 결과가 나타났다(p=.005). 둘째, 근력과 유연성은 상지근력과 하지유연성에서 집단 간과 시기 간 상호작용에서 증가하는 결과가 나타났으며(p=.009)(p=036), 하지근력에서는 운동집단과 통제집단 간 개선효과가 나타났다(p=.006). 또한, 상지유연성은 운동처치 후에 증가하는 결과가 나타났다(p=.020). 셋째, 균형능력 요인은 정적균형에서 운동처치 후 개선 효과가 나타났으며(p=.016), 동적균형에서는 차이가 나타나지 않았다(p>.05). 넷째, 통증정도는 운동처치 후 개선 효과가 나타났으며(p=.022), 운동집단과 통제집단 간에 개선 효과도 나타났다(p=.013). 결론적으로 12주간의 노르딕 워킹은 퇴행성 무릎 관절염을 가진 노인여성의 신체조성과 근력과 유연성에 긍정적인 영향을 미치는 것으로 나타났다. 따라서 노르딕 워킹은 퇴행성 무릎 관절염을 가진 노인여성에게 신체조성과 안정성, 균형성을 높여 주였으며, 무릎 관절의 통증을 낮춰주어 재활 운동 기능 개선에 효과적인 운동방법이라고 사료된다.

녹지의 대기정화효과 분석을 위한 해석적 대기확산모델의 유도 (Analytic Model for Concentration Deficit Profile Caused by a Large Vegetated Area)

  • 김석철
    • 한국대기환경학회지
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    • 제16권5호
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    • pp.539-544
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    • 2000
  • A simple analytic model is proposed here to analyze the concentration deficit field caused by a large area of vegetated area. With non-dimensional deposition velocity chosen as small parameter, the regular perturbation method is exploited to derive the mass balance equation and the dynamic equations for the concentration deficit field, Analytic solutions to those equations are obtained in a closed form for several cases of interest, assuming that the concentration field is stationary and the plume can be nicely approximated as Gaussian for a point source. The results suggest that quite a negligible fraction (less than 1%) of the gaseous air pollutants emitted into the air is removed by the vegetated area of which width is 4 km in wind-wise direction, the typical dimension of the Restricted Development Zones around the metropolitan regions in South Korea.

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가스화 용융로의 운전성능 예측기법에 관한 연구 (A Study of Operation Performance Prediction Method for the Gasification Melting Furnace)

  • 이민도;최상민
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2005년도 제31회 KOSCO SYMPOSIUM 논문집
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    • pp.43-49
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    • 2005
  • Social interest and request about low pollution waste treatment process are growing and gasification melting method, as a new technology concept, is risen. The necessity of engineering analysis to determine design standards and operation condition is required. In this study, the objective and function of components and operation process of various gasification melting furnaces such as shaft type, fluidized bed and Rotary Kiln type gasification melting furnace are reviewed and the design standard and operation range of gasification melting furnace are determined by inspecting the change of output and operation condition with input condition change.

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자동차용 에어컨 시스템의 성능해석에 관한 연구 (A Study on the Performance Analysis of Automotive Air Conditioning System)

  • 이대웅;유성연
    • 설비공학논문집
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    • 제14권4호
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    • pp.304-314
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    • 2002
  • Performance analysis of the automotive air-conditioning system is conducted by using computer simulation, and performance tests are carried out by using the climate wind tunnel in order to verify simulation. Evaporator and condenser were modeled by using empirical correlation which was obtained from calorimeter data, and compressor was modeled by using map based method. The steady state thermodynamic conditions of refrigerant satisfying mass and energy balance were assumed in the simulation program for automotive airconditioning system. The system performance was analyzed by finite difference method until differential air enthalpy between evaporator inlet and outlet becomes converged. Simulation results are in good agreement with experimental results at most operating conditions. Variation of discharge temperature and pressure of compressor, outlet temperature of evaporator, cooling capacity, and COP were investigated in term of air volume flow rate for evaporator, compressor capacity, compressor speed, superheat of thermostatic expansion valve, and diameter of suction line.