• Animal Systematics, Evolution and Diversity
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• v.23 no.2
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• pp.169-173
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• 2007

Two new marine sponges in the family Chalinidae, Haliclona (Haliclona) uljinensis n. sp. and Haliclona (Reniera) hongdoensis n. sp., are collected from Uljin and Hongdo Island, Korea during 2004-2007. H. (H.) uljinensis n. sp. is closely related to H. (H.) oculata in type of spicules. However, ectosomal skeleton of H. (H.) uljinensis n. sp. is reticulated and isodictyal reticulated type but H. (H.) oculata has not any dermal specialization in skeleton. The growth form of H. (H.) uljinensis n. sp. is thin encrusting with numerous cylindrical tubes on the surface but H. (H.) oculata is solid branch form. Haliclona (R.) hongdoensis n. sp. is closely related to H. (R.) aquaeductus in skeletal structure and growth form. However, oxeas of H. (R.) hongdoensis n. sp. are larger than H. (R.) aquaeductus's.

• Animal Systematics, Evolution and Diversity
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• v.34 no.2
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• pp.79-91
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• 2018

Three new genera and species of siphonostomatoid copepods are described as associates of sponges from shallow water of Samar Island in the Philippines: Samarus filipes n. gen., n. sp., Paurocheres dentatus n. gen., n. sp., and Platymyzon umbonatum n. gen., n. sp. A new family Samarusidae is proposed to accommodate Samarus n. gen. which has rudimentary legs 1-5 represented only by filiform setae. Paurocheres n. gen. is characterized by 2-segmented endopod of leg 4 and reduced setation of legs, and Platymyzon n. gen. by missing of mandibular gnathobase.

• Animal Systematics, Evolution and Diversity
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• v.33 no.2
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• pp.73-99
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• 2017

Six new species of siphonostomatoid copepods are described from sponges collected in the Philippines and Vietnam. Two new genera of Asterocheridae, Andapontius and Holobinus, are proposed. The new species are Andapontius granulatus n. gen. n. sp., Holobinus angustus n. gen. n. sp. and Dermatomyzon boxshalli n. sp. in the family Asterocheridae and Entomopsyllus brevicaudatus n. sp., Paralepeopsyllus leei n. sp. and P. dambayensis n. sp. in the family Entomolepididae. Doropontius denticornis Thompson and Scott, 1903, is redescribed for the first time since its original record.

• 한국생물공학회:학술대회논문집
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• 2003.10a
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• pp.67-67
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• 2003

• Proceedings of the Microbiological Society of Korea Conference
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• 2002.10a
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• pp.94-99
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• 2002

The oceans cover about $71\%$ of the Earth's crust and contain nearly 300,000 described species. Free-living bacteria in the sea and symbiotic bacteria of marine invertebrates are proving to be valuable sources of useful bioactive compounds. Marine sponges, in particular, which contain diverse communities of bacteria, produce many classes of compounds that are unique to the marine environment. Uncultured microorganisms are commonly believed to represent $99.9\%$ of the whole microbial community. They have been investigated for the possibility of isolating and over-expressing genes in viable microorganisms. Strict symbiotic species that have been adapted to the host are candidate unculturable species. With the enormous potential for discovery, development, and market value of marine derived compounds, supply of the products is a major limiting factor for further development.

• Fisheries and Aquatic Sciences
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• v.17 no.2
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• pp.215-222
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• 2014

To explore marine microorganisms with medical potential, we isolated and identified marine bacteria from floats, marine algae, animals, and sponges collected from Jeju Island, Korea. We isolated and identified 21 different strains from the marine samples by 16S rRNA analysis, cultured them in marine broth, and extracted them with ethyl acetate (EtOAc) to collect secondary metabolite fractions. Next, we evaluated their anti-oxidative and anti-inflammatory effects. Among the 21 strains, the secondary metabolite fraction of Bacillus badius had both strong antioxidant and anti-inflammatory activity, and thus was selected for further experiments. An antioxidant compound detected from the secondary metabolite fraction of B. badius was purified by preparative centrifugal partition chromatography (n-hexane:EtOAc:methanol:water, 4:6:4:6, v/v), and identified as diolmycin A2. Additionally, diolmycin A2 strongly inhibited nitric oxide production. Thus, we successfully identified a significant bioactive compound from B. badius among the bacterial strains collected from Jeju Island.

• Fisheries and Aquatic Sciences
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• v.17 no.3
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• pp.275-290
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• 2014

The marine ecosystem represents a vast and dynamic array of bio-resources attributed with its huge diversity and considered as potential untapped reservoirs for the development of functional foods for future health markets. Basically, marine microorganisms, sponges, algae, invertebrates such as crustaceans and mollusks along with marine fish species can be considered as marine bio-resources, which can be utilized to obtain different health benefits for humans, directly or after processing. Most of the bio-molecular components, such as lipids and proteins from these marine bio-resources, which can be extracted in large scale using the modern and advanced biotechnological approaches, are suitable drug candidates for the pharmaceutical industry as well as functional food ingredients for the food industry. Moreover, the furtherance of high throughput molecular biological techniques has already been incorporated with identification, mining and extraction of molecular components from marine bio-resources. In this review, potential marine bio-resources with respect to their extractable bio-molecules were described in details, while explaining the present and prospective methods of identification and extraction, which are integrated with advanced techniques in modern biotechnology. In addition, this provides an overview of future trends in marine biotechnology.

• Journal of Microbiology
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• v.40 no.2
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• pp.161-165
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• 2002

Isolation frequency of microorganisms from marine sources was examined with different media and samples collected from the coastal area of Cheju Island. From sea water samples, about 1% of microorganisms from the total number of bacteria were recovered. Microorganisms were cultured at the much lower frequency of 10$\^$-4/-10$\^$-6/ from other marine sources such as sediment, sponges and corals. The frequency of duplicated isolation was examined with 140 morphologically different colonies isolated on different media. Fourteen percent of them exhibited the same morphology on two different media. The duplication frequency of the isolates among three different media was 33%.

• Korean Journal of Pharmacognosy
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• v.31 no.4
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• pp.401-406
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• 2000

Marine sponges are known to be a source of diverse sterols. In our study on the cytotoxic components of the marine sponge Spirastrella abata, $5{\alpha},8{\alpha}-epidioxy\;{\Delta}^6$ sterols (1-5) and $5{\alpha},8{\alpha}-epidioxy\;{\Delta}^{6,9(11)}$ sterols (6-7) were isolated. The structures were identified based on the analyses of $^1H-NMR,\;^{13)C-NMR$, and MS data. These compounds were assayed for cytotoxicity against 5 human solid tumor cell lines including A549, SK-OV- 3, SK-MEL-2, XF498, and HCT15.

• Animal Systematics, Evolution and Diversity
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• v.35 no.4
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• pp.200-203
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• 2019

A new marine sponges, Mycale (Carmia) ieoensis n. sp., of the family Mycalidae was collected SCUBA diving in June 2017 from Ieodo Ocean Research Station, Korea. M. (C.) ieoensis n. sp. is encrusting to irregular massive type, yellow in life. This new species is similar to M. nullarosette Hoshino, 1981 in color and growth form but it differs in spicule size and sigma shape. Spicule size of M. (C.) ieoensis n. sp. smaller than that M. nullarosette. Also, M. (C.) ieoensis n. sp. has two size toxa, but M. nullarosette is not. The new species are compared to other Mycale species from the Korean region, and similar species from elsewhere.