• Korean Journal of Clinical Laboratory Science
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• v.49 no.4
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• pp.323-328
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• 2017

Angiogenesis is a process including members of the angiogenic factors. In particular, fibroblast growth factor 2 (FGF2) is considered the most potent angiogenic factor because it promotes cell proliferation and tube formation. A recent study reported that fucoidan derived from marine plant potentiated FGF-2 induced tube formation in human endothelial cells. On the other hand, the molecular mechanisms involved in the angiogenic activity of fucoidan and FGF2 are unknown. In this study, a fucoidan treatment promoted angiogenesis induced by FGF2. The effects of fucoidan on FGF2-induced angiogenesis were confirmed by a proliferation assay using a CellTiter96 Aqueous One solution after a treatment with fucoidan and FGF2. The tube formation and wound healing assay for the angiogenic activity were also confirmed. Reverse transcription PCR showed a change in the mRNA of vascular endothelial growth factor-A (VEGF-A), intercellular adhesion molecule-1 (ICAM-1), matrix metallopeptidase9 (MMP9), and the signal transducer and activator of transcription3 (STAT3). In summary, the Fucoidan/FGF2 treatment induced an increase in cell proliferation, improved the tube formation and wound healing activity, and altered the STAT3, VEGF-A, ICAM-1, and MMP9 mRNA expression levels. Further research will be needed to provide a scientific explanation in terms of cell-signaling and confirm the present findings.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.14 no.4
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• pp.423-434
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• 2016

The importance of severe nuclear accidents and probabilistic safety assessment (PSA) were brought to international attention with the occurrence of severe nuclear accidents caused by the extreme natural disaster at Fukushima Daiichi nuclear power plant in Japan. In Korea, studies on level 3 PSA had made little progress until recently. The code systems of level 3 PSA, MACCS2 (MELCORE Accident Consequence Code System 2, US), COSYMA (COde SYstem from MAria, EU) and OSCAAR (Off-Site Consequence Analysis code for Atmospheric Releases in reactor accidents, JAPAN), were reviewed in this study, and the disadvantages and limitations of MACCS2 were also analyzed. Experts from Korea and abroad pointed out that the limitations of MACCS2 include the following: MACCS2 cannot simulate multi-unit accidents/release from spent fuel pools, and its atmospheric dispersion is based on a simple Gaussian plume model. Some of these limitations have been improved in the updated versions of MACCS2. The absence of a marine and aquatic dispersion model and the limited simulating range of food-chain and economic models are also important aspects that need to be improved. This paper is expected to be utilized as basic research material for developing a Korean code system for assessing off-site consequences of severe nuclear accidents.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.4
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• pp.191-199
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• 2013

It is estimated and analyzed that the design wave height and the confidence interval (hereafter CI) according to the return period using the fourteen-year wave data obtained at Pusan New Port. The functions used in the extreme value analysis are the Gumbel function, the Weibull function, and the Kernel function. The CI of the estimated wave heights was predicted using one of the Monte-Carlo simulation methods, the Bootstrap method. The analysis results of the estimated CI of the design wave height indicate that over 150 years of data is necessary in order to satisfy an approximately ${\pm}$10% CI. Also, estimating the number of practically possible data to be around 25~50, the allowable error was found to be approximately ${\pm}$16~22% for Type I PDF and ${\pm}$18~24% for Type III PDF. Whereas, the Kernel distribution method, a typical non-parametric method, shows that the CI of the method is below 40% in comparison with the CI of the other methods and the estimated design wave height is 1.2~1.6 m lower than that of the other methods.

• Journal of the Korean Society of Food Science and Nutrition
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• v.9 no.1
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• pp.15-22
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• 1980

In this study, two species of algae, Ecklonia stolonifera, Sargassum thunbergii and one species of marine plant, Zostera marina(rhizoid and stem) were collected and extamined to determine the extractability of water soluble protein and the influences of various factors including extraction time, temperature, ratio of sample vs solvent and pH upon the extractability were tested. The effects of precipitation treatments for isolation of algal protein from the extracts(TCA treatment, methanol treatment and pH control) were also tested. Amino nitrogen and total nitrogen of purified samples made by obtained optimum conditions were estimated. The effect of the ratio of sample vs solvent on extractability differed from species to species which was enhances at 1:100(w/v) in Sargassum thunbergii and Zostera marina while 1:150(w/v) for Ecklonia stolonifera. The effect of extraction time and temperature was revealed differently in all species which might be considered to be caused by differences in the constitution of algal tissues. But in case of TCA insoluble nitrogen, it was showed the maximum extractability at $40-50^{\circ}C$ for 1 hour extraction. The optimum pH for the ext action of total nitrogen was 9-12 while the optimum pH was 6-7 for TCA insoluble nitrogen. And the pH control appeared to be most effective in the influence of precipitation treatment for isolation of algal protein.

• 한국지구물리탐사학회:학술대회논문집
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• 2002.09a
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• pp.46-66
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• 2002

High-resolution multichannel seismic data were collected in the coastal area near the Gori nuclear power plant to investigate Quaternary fault pattern and timing. A 12 channel streamer, a sparker, and a portable recorder were used for data acquisition. Because the group interval of the streamer was 6.25 m and the sparker can generate acoustic waves with the frequency content of up to 500 Hz, the data show a significant improvement both in horizontal and vertical resolution. The area surveyed is covered with 30-40 m thick Holocene sediments that constitute the mud belt along the southeastern coast of Korea. The survey area is characterized by the well discriminated Pleistocene and Holocene boundary and shallow gas-charged zones. A number of Quaternary faults were found in the sediment column, that are nearly vertical and extend north-south. The Quaternary faults, arranged at a spacing of a few hundred meters, suggest that they were formed in response to compression, although some of them reveal extensional characteristics. Locally, faults disrupt Incised-channel fills that are interpreted to have formed in the early stage of transgression after the beginning of the Holocene. Seismic sections suggest that shallow gas in the mud belt sediments made its way upward through the fractured fault planes. The tectonism responsible for the opening of the East Sea has not persisted since the late Miocene, but vigorous Quaternary faulting activity in the vicinity of the southeastern Korean Peninsula indicates that tectonic stability has yet to be achieved in this region underlain by the hotter than normal mantle.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.31 no.1
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• pp.56-62
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• 1998

Seasonal variations of eelgrass and epiphytic algae in eelgrass beds in Kwangyang Bay were studied from January 1994 to December 1994. A peak of the shoot length and standing crop of eelgrass occurred in summer, but low values were observed in fall and winter. The dominant species of epiphytic algae were Callophyllis rhynchocarpa and Champia sp. In spring and summer, while Polysiphonia japonica and Lomentaria hakodatensis in fall and winter. In contrast to the eelgrass, the standing crop of epiphytic algae showed a minimum in summer. There was a gradual increase in the standing crop of epiphytic algae during fall, and a peak of standing crop occurred in winter. Epiphytic algae accounted for approximately $15\~20\%$ of total plant standing crops of the eelgrass meadows. Correlation analysis with environmental factors indicated that temperature influences on both the standing crop of eelgrass and epiphytic algae. There was a positive relationship between the standing crop of eelgrass and temperature, while there was a reverse relationship between that of epiphytic algae and temperature.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.32 no.4
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• pp.444-451
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• 1999

The effect of individual density on the growth and survival of Laminaria japonica was experimentally evaluated. Four density treatments of young sporophytes (0.63 cm In maximum length) grown in the laboratory were transplanted to the southeastern coast of Korea and their survivorship and growth rate were measured twice a month from January to July, 1996. Plants showed higher survivorship at low density. Final densities at three lowest densities were similar, ranging from 34 to 38 inds${\cdot}100 cm^{-2}$. Planis at the highest density, however, suffered greater decline than at lower densities, and only 21 plants remained at the end of this study. Mean frond size (length and width) fluctuated throughout the study period at four densities. During the first two mouths after outplanting, mean frond size was negatively correlated with initial density, However, the size was density independent after three months. As stand density increased, size-frequency distribution through time tended to be more positively skewed. The 10 largest plants grew faster in frond size and attained larger size in the lower density. There was a positive relationship between plant size and relative growth rate (or survival). The slope of yield-density (Y-D) relationships at four densities ranged from -0.060 to -0.137. The study suggests that density can strongly affect the survival and growth of this alga. The density-dependent survival and growth patterns, however, were not strictly consistent with those of terrestrial plants.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.6
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• pp.123-132
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• 2012

Gas sensors has been used very differently that depending on following purposes; Automotive (exhaust gas, fuel mixture gas, oxygen, particulates), agriculture / food industry (fresh, stored, CO2, humidity, NH3, nitrogen oxide gas, organic gas, toxic gas emitted from pesticides and insecticides), industrial / medical (chemical gas, hydrogen, oxygen and toxic gases), military (chemical weapon), environmental measurements (CO and other air pollution consisting of sulfur and nitrogen gas), residential (LNG, LPG, butane, indoor air, humidity). The types of industrial toxic substances are known about 700 species and many of these exist in gaseous form under normal conditions. he multi-gas detection sensors will be developed for casualties that detect the most important and find easy three kinds of gases in marine plant; carbon dioxide(CO2), carbon(CO), ammonia(NH3). Package block consists of gas sensing device minor ingredient, rf front end, zigbee chip. Develope interworking technology between the sensor and zigbee chip inside a package. Conduct a performance test through test jig about prototype zigbee sensor module with rf output power and unwanted emission test. This research task available early address when poisonous gas leaked from large industrial site and contribution for workers' safety at the enclosed space.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.373-378
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• 2019

In the marine area, the salt concentration in the soil increases, and the inland heavy metal pollution increases the damage of plants. In the inland industrial development area, researches on the genetic resources of plants together with the heavy metal accumulation of Co, Ni, Zn, and so on are required. Both of these problems have caused scientists to work hard to find plants that are likely to cause stress in plant roots. In this study, seeds of Arabis stelleri var. japonica collected near the shore were used for germination. The growth and development and tolerance of both Arabis and Arabidopsis seeds were investigated under laboratory culture conditions. As a result, Arabis showed resistance about 3 times in 250 mM nickle and cobalt, and more than 4 times in 1 mM zinc when compared to Arabidopsis. The tolerance of Arabis to Na salts increased by 20% or more at 50 mM concentration and Arabis was resistant to heavy metals and salt concentration. The accumulation of Na ions in the body was measured as a preparation for studying the intracellular mechanism. As a result, it showed a further decrease in resistance to ground water roots. It is considered that the activity of the exporting gene is important rather than the mechanism of accumulation.

• Ecology and Resilient Infrastructure
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• v.8 no.2
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• pp.97-111
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• 2021

This study was conducted to develop a habitat type classification system and its map based on the ecological characteristics of species, spatial type, vegetation, topography, and geological conditions preferred by species. To evaluate the relationships between species and their habitats in Korean national parks, we prepared a classification standard table for systematic classification of habitat types. This classification system divides habitats into 6 low-level and 59 mid-level ecological classes based on habitat structure. The mid-level system divided forest ecosystems into 20 subtypes, stream and wetland ecosystems into 8 types, coastal ecosystems into 7 types, arable land into 6 types, development land into 9 types, and 1 type of marine ecosystem. A habitat classification map was drawn utilizing square images, detailed vegetation maps, and forest stand maps, based on the above habitat classification system, and it covered 1,461 plots spanning 21 national parks. The habitat classification system and survey protocol, which consider domestic habitat conditions, should be further developed and applied to habitat assessment, to enhance the utility of this study.