• East Asian mathematical journal
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• v.37 no.2
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• pp.265-288
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• 2021

In the 2015 revised mathematics curriculum, the system of equations is first introduced in 'Variables and Expressions' of [Middle School Grades 1-3]. Then, It is constructed that after learning the linear function in 'Functions', the relationship between the graphs of two linear functions and the systems of linear equations are learned so that students could improve the geometric representation of the systems of equations. However, in of Elective-Centered Curriculum Common Courses, Instruction is limited to algebraic manipulation when teaching and learning systems of quadratic equations. This paper presented the teaching and learning method that can improve students' mathematical connection through various representations by providing geometric representations in parallel using GeoGebra, a mathematics learning software, with algebraic solutions in the teaching and learning situation of simultaneous quadratic equations.

• Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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• 2001.06a
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• pp.1191-1191
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• 2001

Generation of precise, accurate, and robust calibration models for spectroscopic methods of analysis can be time-consuming, expensive, and sometimes difficult to achieve. For these reasons, efforts have been made to find ways in which the calibration from one instrument can be moved to another with minimal performance reduction. A slight shift in nomenclature from the common term calibration transfer to the term calibration transport is used here to help resolve the subtle difference between two means of moving a calibration from one instrument to another. The former term denotes a transfer procedure that includes mathematical manipulation of the calibration data via some determined transfer function, whereas the latter term does not. Todays generation of process and laboratory FTNIR analyzers is capable of not only achieving calibration transfer, but also calibration transport often without the need of slope or bias adjustments. Several studies are used to examine the boundaries of the extent to which calibration transport is achieved in the refining industry. Data collected on multiple on-line and laboratory FTNIR analyzers located in multiple countries are considered, and the ultimate limitations discussed.

• Journal of the Korean Society for Precision Engineering
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• v.13 no.3
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• pp.150-157
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• 1996

In this paper, to develop a smart CAD/CAM system for systematically performing from the 3-D solid shape design of products to the CNC cutting operation of products by a machining center, a B-Rep solid modeler is realized based on the half edge data structure. Because the B-Rep solid modeler has the various capabilities related to the solid definition functions such as the creation operation of primitives and the translational and rotational sweep operation, the solid manipulation functions such as the split operation and the Boolean set operation, and the solid inversion function for effectively using the data structure, the 3-D solid shape of products can be easily designed and constructed. Also, besides the automatic generation of CNC code, the B-Rep solid modeler can be used as a powerful tool for realizing the automatic generation of finite elements, the interfer- ence check between solids, the structural design of machine tools and robots and so on.

• IMMUNE NETWORK
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• v.20 no.1
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• pp.4.1-4.17
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• 2020

Tregs have a role in immunological tolerance and immune homeostasis by suppressing immune reactions, and its therapeutic potential is critical in autoimmune diseases and cancers. There have been multiple studies conducted on Tregs because of their roles in immune suppression and therapeutic potential. In tumor immunity, Tregs can promote the development and progression of tumors by preventing effective anti-tumor immune responses in tumor-bearing hosts. High infiltration of Tregs into tumor tissue results in poor survival in various types of cancer patients. Identifying factors specifically expressed in Tregs that affect the maintenance of stability and function of Tregs is important for understanding cancer pathogenesis and identifying therapeutic targets. Thus, manipulation of Tregs is a promising anticancer strategy, but finding markers for Treg-specific depletion and controlling these cells require fine-tuning and further research. Here, we discuss the role of Tregs in cancer and the development of Treg-targeted therapies to promote cancer immunotherapy.

• Korean Journal of Acupuncture
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• v.25 no.4
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• pp.73-88
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• 2008

Objective : The aim of this research was to investigate the effect on five element constitutional acupuncture(Sa-am acupuncture) at 4 acupoints by needle manipulation to sedate Six Fu-Organ on hyperlipidemia induced by high fat diet in rats. Method : We recorded data of weight gain, food intake, food efficiency, weight of liver, heart, spleen, lung, kidney, levels of total cholesterol, triglyceride, HDL-cholesterol, AST, ALT in serum of rats fed high fat diet for 5 weeks. Spraque Dawley rats were divided into eight groups(normal; normal diet and non-acupuncture group, control; non-acupuncture group, Acu-LI; acupuncture at $SI_5{\cdot}LI_5{\cdot}BL_{66}{\cdot}LI_2$ group, Acu-ST; acupuncture at $GB_{41}{\cdot}ST_{43}{\cdot}LI_1{\cdot}ST_{45}$, Acu-SI; acupuncture at $BL_{66}{\cdot}SI_2{\cdot}ST_{36}{\cdot}SI_8$, Acu-BL; acupuncture therapy at $ST_{36}{\cdot}BL_{40}{\cdot}GB_{41}{\cdot}BL_{65}$, Acu-TE; acupuncture at $BL_{66}{\cdot}TE_2{\cdot}ST_{36}{\cdot}TE_{10}$, Acu-GB; acupuncture at $LI_1{\cdot}GB_{44}{\cdot}SI_5{\cdot}GB_{38}$. After needles inserted, it was rotated clockwise and anticlockwise 12 times on rats fed high fat diet. Results : The body weight was decreased in Acu-SI, Acu-TE, Acu-GB group, /the food intake was decreased in Acu-TE, / the food efficiency was decreased in Acu-SI, /serum triglyceride was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-GB, /serum total cholesterol was decreased in Acu-LI, Acu-BL, serum ALP was decreased in Acu-LI, Acu-ST, Acu-BL, Acu-TE, Acu-GB. While the relative weight of heart was increased in Acu-LI, Acu-SI, the relative weight of kidney was increased in Acu-SI, Acu-GB. Conclusion : These results suggest that five element constitutional acupuncture(Sa-am acupuncture) may be having an therapeutic influence on hyperlipidemia induced by high fat diet. Further researches of acupuncture manipulation are needed in the future based on our study.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.3
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• pp.157-161
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• 2010

Heat shock proteins (HSPs) are specifically induced by various forms of stress. Hsp70.1, a member of the hsp70 family is known to play an important role in cytoprotection from stressful insults. However, the functional role of Hsp70 in motor function after spinal cord injury (SCI) is still unclear. To study the role of hsp70.1 in motor recovery following SCI, we assessed locomotor function in hsp70.1 knockout (KO) mice and their wild-type (WT) mice via the Basso, Beattie and Bresnahan (BBB) locomotor rating scale, before and after spinal hemisection at T13 level. We also examined lesion size in the spinal cord using Luxol fast blue/cresyl violet staining. One day after injury, KO and WT mice showed no significant difference in the motor function due to complete paralysis following spinal hemisection. However, when it compared to WT mice, KO mice had significantly delayed and decreased functional outcomes from 4 days up to 21 days after SCI. KO mice also showed significantly greater lesion size in the spinal cord than WT mice showed at 21 days after spinal hemisection. These results suggest that Hsp70 has a protective effect against traumatic SCI and the manipulation of the hsp70.1 gene may help improve the recovery of motor function, thereby enhancing neuroprotection after SCI.

• Journal of the Korea Society of Computer and Information
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• v.12 no.6
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• pp.69-76
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• 2007

The main stream of presentation is interrupted because of the direct manipulation of their PC frequently so as to control the screen and file open and so on. A variety of products have been developed to solve these inconveniences of the conventional laser beam pointer [LBP] by simply adding a mouse function to the previous LBP. However. the LBPs fully supporting a mouse function are not yet appeared. In this paper. we developed the LBP fully fulfilling a mouse function using mono-camera as well as a robust image processing and analyzed the position detection accuracy. Finally we verified the developed LBP does not only fulfill a mouse function but also solve the defects of the current laser pointer such as inconvenient installation and Position detection errors due to the illumination and viewing direction changes.

• Journal of the Korean Society of Clothing and Textiles
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• v.16 no.3 s.43
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• pp.181-195
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• 1992

The purposes of this study were to investigate 1) the effect of body exposure and color of a woman's suit on the perception of modesty, and 2) the effect of perceiver's sex and age on impression formed by the function of clothing variables. The instrument of this study consisted of a response scale and stimuli. Thirteen items of 7-point semantic differential scales were developed to measure the perceiver's impression on wearer's modesty. Stimuli were color pictures of a model wearing one of 8 types of suit constructed by a 2 $\times$ 2 $\times$ 2 factorial design. The manipulation of each level of the clothing variables were: color of the suit by black and red, leg exposure by varying skirt lengths to a Chanel-line and mini skirt, and neck exposure by shirt collar blouse and scarf. Two models, representing typical female college students living in Seoul, were selected to eliminate model effect. The sample include 384 subjects, consisting of 4 groups of male and female college students and middle aged men and women. Eight experimental groups were randomly assigned to one of eight stimuli based on between-subject design. One half of each group responded to model 1 and the other half to model 2 of same stimulus. Responses to the semantic differential scales were factor analyzed (pc model, Varimax rotation) to identify factors constructing impression of modesty. Two factors emerged regard­less of subgroups; Elegance and Extroversion factor. The first factor was found to be dominant, accounting for 60 percent of the total variance. The other accounted for just 11 percent. Multidimensional ANOVA (5-way, 3-way) was conducted to test the effect of the clothing variables against two factors identified from the factor analysis. Leg exposure was the most powerful variable affecting the impression of Elegance and Extroversion factor for all per. ceiver subgroups. Neck exposure had primary effect on the impression of Elegance, whereas it partially influenced that of Extroversion. Color of suit had only partial effect on the impression of Extroversion. Hypothesis I was partially supported from the findings above. The effect of perceiver's age and sex on impression by the function of clothing variables was tested by comparing the result between four subgroups. In forming an impression of the wearer's modesty, male college students were least affected by the manipulation of clothing variables, while middle aged males were affected most. In the female groups, there was no age difference and they fell between the male groups in the degree to which they were affected. Hypothesis II was supported only by age difference in two male groups, and by sex difference in two student groups.

• KIPS Transactions on Computer and Communication Systems
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• v.8 no.9
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• pp.217-224
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• 2019

Recently, sensor networks are built and used on many kinds of fields such as home, traffic, medical treatment and power grid. Sensing data manipulation on these fields could be a serious threat on property and safety. Thus, a proper way to block sensing data manipulation is necessary. In this paper, we propose IoT(Internet of Things) sensing data validation mechanism based on data obfuscation and variance analysis to remove manipulated sensing data effectively. IoT sensor device modulates sensing data with obfuscation function and sends it to a user. The user demodulates received data to use it. Fake data which are not modulated with proper obfuscation function show different variance aspect with valid data. Our proposed mechanism thus can detect fake data by analyzing data variance. Finally, we measured data validation time for performance analysis. As a result, block rate for false data was improved by up to 1.45 times compared with the existing technique and false alarm rate was 0.1~2.0%. In addition, the validation time on the low-power, low-performance IoT sensor device was measured. Compared to the RSA encryption method, which increased to 2.5969 seconds according to the increase of the data amount, the proposed method showed high validation efficiency as 0.0003 seconds.

• Journal of the Korea Convergence Society
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• v.10 no.9
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• pp.55-61
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• 2019

The purpose of this study was to investigate the correlation between the hand dexterity and grip strength of 8-10 year elementary school children and 20-24 year college students. This study was conducted on 77 elementary school children aged 8-10 years old and 50 college students aged 20-24 years. The chopsticks manipulation test (CMT) and dymanomenter were used to evaluated hand dexterity and grip strength. In this study, the correlation between hand dexterity and grip strength, and the age, hand dexterity and grip strength of the subjects were compared. hand dexterity between 8-10 year old and 20-24 year old students were statistically different between 8 and 9 year olds, and the control was between 8 and 20-24 year old students. There were statistically significant differences. In addition, in the correlation between age, hand dexterity and grip strength, age and grip strength were positively correlated, and age and hand dexterity were negatively correlated. These results may contribute to the development of children's hand function and the fusion approach.