• 한국재난정보학회 논문집
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• 제19권4호
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• pp.882-896
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• 2023

연구목적: 국가산업단지 공장시설물이 보유한 내진설계의 잠재적 위험과 안전지도 및 점검의 미비점을 효과적으로 향상시킬 수 있는 안전관리 및 내진보강대책 마련을 목적으로 한다. 연구방법: 본 연구에서는 국가산업단지의 지진재난 대비 안전관리 현황 및 관리체계 등 지진재난 안전관리 전반에 관한 조사·분석을 통해 문제점 및 개선방안을 도출하였고, 국가산업단지 내 입주기업체 내진설계 실태조사를 실시하여 시설유형과 구조적 특성에 기반한 개선방안을 제시하였다. 연구결과: 결론적으로 국가산업단지 지진재난 대비 안전관리 및 내진보강에 대한 문제점을 정리하여 4가지 유형별(내진성능 평가 및 관련 제도 보완, 입주기업 및 지자체 권한, 내진보강 및 안전관리 지원대책, 조직의 역량강화)로 개선방안을 도출하였다. 결론: 이를 기반으로 국가산업단지 입주기업이 지진재난을 대비하여 추진해야 하는 내진보강 대책을 마련하였으며, 각 대책별 세부적인 방안을 제시하였다.

• 한국화재소방학회논문지
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• 제27권6호
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• pp.115-121
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• 2013

산업시설의 대형, 첨단화에 따라 각 산업현장에서 다양한 종류의 유해 위험물질이 대량으로 사용되고 있다. 이에 따라 독성누출, 화재, 폭발 등의 중대산업사고가 지속적으로 발생되고 있으며 그 위험은 점점 높아지고 있는 실정이다. 여러 예방 시스템 중 Process Safety Management (PSM, 공정안전관리)제도가 있지만 아직까지도 제도의 취지와는 다르게 자율적인 운영보다는 해당 관청의 지도 점검에 맞추어 PSM 제도가 운영되고 있어 보이지 않는 중대위험이 잠재한 대규모 PSM 사업장의 안전성 확보에는 한계가 있다고 할 수 있다. 사업장의 안전시스템을 검증하기 위해서는 기존 시스템의 보완이 절실히 요구된다. 이에 본 연구에서는 PSM 자체감사의 중요성을 강조하고, 현재 제도의 문제점을 분석하여, 이에 대한 시스템 검증으로 제도 개선의 제안과 효율적인 자체감사 운영을 통해 자율 안전성을 강화하도록 하였으며, 또한 제도적으로도 이를 뒷받침할 수 있는 방법을 연구하여 제안하였다.

• Nutrition Research and Practice
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• 제16권2호
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• pp.161-172
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• 2022

BACKGROUND/OBJECTIVES: Colorectal cancer (CRC) is the third most common cancer worldwide and has a high recurrence rate, which is associated with cancer stem cells (CSCs). β-carotene (BC) possesses antioxidant activity and several anticancer mechanisms. However, no investigation has examined its effect on colon cancer stemness. MATERIALS/METHODS: CD133⁺CD44⁺ HCT116 and CD133⁺CD44⁺ HT-29 cells were isolated and analyzed their self-renewal capacity by clonogenic and sphere formation assays. Expressions of several CSCs markers and Wnt/β-catenin signaling were examined. In addition, CD133⁺CD44⁺ HCT116 cells were subcutaneously injected in xenograft mice and analyzed the effect of BC on tumor formation, tumor volume, and CSCs markers in tumors. RESULTS: BC inhibited self-renewal capacity and CSC markers, including CD44, CD133, ALDH1A1, NOTCH1, Sox2, and β-catenin in vitro. The effects of BC on CSC markers were confirmed in primary cells isolated from human CRC tumors. BC supplementation decreased the number and size of tumors and delayed the tumor-onset time in xenograft mice injected with CD133⁺CD44⁺ HCT116 cells. The inhibitory effect of BC on CSC markers and the Wnt/β-catenin signaling pathway in tumors was confirmed in vivo as well. CONCLUSIONS: These results suggest that BC may be a potential therapeutic agent for colon cancer by targeting colon CSCs.

• 한국가스학회지
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• 제27권2호
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• pp.16-24
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• 2023

산업에서 발생할 수 있는 각종 위험을 발굴하고 제어하는 리스크관리에서 기업의 지속 가능한 발전을 목표로 ESG(환경·사회·지배구조)경영을 도입하고 있다. 앞으로는 기업 지속가능성에 대한 가치 판단 도구로써 ESG 평가가 더욱 활용될 것이다. 이러한 ESG 평가를 활용하여 기업의 사고 예방 정도를 관리하고 있다. 현행 ESG 평가체계에 대한 형태소 분석을 통하여 안전에 대한 평가항목을 분석하여, ESG에서 활용 가능한 정량적 '안전평가지표'가 미흡함을 알았다. 본 연구에서는 국내외 산업 사고 데이터를 분석하고 집중 관리가 필요한 '사고 기여 인자'를 도출했으며, 해당 결과를 기반으로 보완이 필요한 주요 안전관리 항목을 선정했다. 선정한 항목들은 '사고 예방 관리'에 적합한 평가 요소로 최적화시키는 과정을 거쳐, ESG 안전 평가지표를 개발하였다.

• 한국직업건강간호학회지
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• 제21권3호
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• pp.308-316
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• 2012

Purpose: The purpose of this study was to describe the perception and practice of hospital infection control of nursing staff in long-term care hospitals by the level of supplementation of nurses. Methods: The participants were 212 nurses and nurse assistants in 13 long-term care hospitals in a metropolitan city and the data were gathered by self-reported questionnaires during August 2011 and analyzed by SPSS/WIN program. Results: The beds per a nurse were 15, and the proportion of nurses among nursing staff in long-term care hospitals was about 33%. In general, the level of infection control in practice was lower than that of perception. The highest perception and practice domain was 'Management of disinfection/contamination', and the lower level domains were 'Personal hygiene' and 'Hand washing' There were statistically significant differences in the hospital infection control of perception and practice depending on age, education, career in long-term care hospital, job position, the quantity of beds, nurse, and nurse assistant, beds per a nurse and proportion of nurses in hospitals. Conclusion: According to these results, the systematic and continual education on hospital infection control of the nursing staff in long-term hospitals should be carried out. In addition, the policy to add more nurses into long-term care hospitals must be implemented.

• Preventive Nutrition and Food Science
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• 제22권1호
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• pp.45-49
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• 2017

The anti-obesity effects of yeast hydrolysate (YH) supplementation (1.0 g/d) have already been demonstrated. We investigated whether a low dose of YH (0.5 g/d, YH-500) also has the anti-obesity effects. Thirty obese women were randomly assigned to the control or YH-500 groups. After 8 weeks, weight and body mass index were significantly reduced by the YH treatment (0.5 g/d) (P<0.05). The YH-500 group lost a significant amount of body fat after the 8-week treatment: fat mass 25.9 kg (baseline) versus 23.8 kg (8th week), P<0.01; fat mass ratio 38.8% (baseline) versus 36.5% (8th week), P<0.05. The YH-500 group showed a significant reduction in calorie intake during the 8-week treatment (P<0.001). The control group wanted to eat much more food (P<0.05) and sometimes thought about eating more often compared with the YH-500 group (P<0.05). Whereas the control group showed a slightly increased sweet preference, the YH-500 group showed a significant reduction in sweet preference (P<0.05). In conclusion, low dose YH supplementation (0.5 g/d) may induce a reductions in weight and body fat in obese women via the reduction of calorie intake.

• 디지털융복합연구
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• 제15권1호
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• pp.571-581
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• 2017

본 연구는 12주간 대사증후군 중년 여성들의 코코넛 오일 섭취와 복합운동이 신체조성, 산화스트레스 및 혈압에 미치는 영향을 규명하고자 하였다. 측정항목은 체지방(체중, 체지방, BMI, WHR), 산화스트레스(MDA, SOD), 혈압(SBP, DBP)을 측정하였다. 그 결과, 체중과 체지방에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 감소하였다. BMI, WHR에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 감소하였다. MDA에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 감소하였다. SOD에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 증가하였다. 수축기 혈압에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 감소하였다. 이완기 혈압에 있어서 코코넛 오일, 복합운동 프로그램 참여 전에 비해 후에 유의하게 감소하였다. 결론적으로 대사증후군 중년 여성들에 있어서 코코넛 오일 섭취와 복합운동은 체지방, 산화스트레스, 혈압 관리에 효과적인 것으로 나타났다.

• Journal of Ginseng Research
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• 제38권4호
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• pp.239-243
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• 2014

Background: To investigate the antidiabetic effects of hydrolyzed ginseng extract (HGE) for Korean participants in an 8-wk, randomized, double-blinded, placebo-controlled clinical trial. Methods: Impaired fasting glucose participants [fasting plasma glucose (FPG) ${\geq}5.6mM$ or < 6.9mM who had not been diagnosed with any disease and met the inclusion criteria were recruited for this study. The 23 participants were randomly divided into either the HGE (n = 12, 960 mg/d) or placebo (n = 11) group. Outcomes included measurements of efficacy (FPG, postprandial glucose, fasting plasma insulin, postprandial insulin, homeostatic model assessment-insulin resistance, and homeostatic model assessment-${\beta}$) and safety (adverse events, laboratory tests, electrocardiogram, and vital signs). Results: After 8 wk of HGE supplementation, FPG and postprandial glucose were significantly decreased in the HGE group compared to the placebo group. No clinically significant changes in any safety parameter were observed. Our study revealed that HGE is a potent antidiabetic agent that does not produce noticeable adverse effects. Conclusion: HGE supplementation may be effective for treating impaired fasting glucose individuals.

• 한국식품영양학회지
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• 제28권4호
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• pp.685-694
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• 2015

In the present study, we conducted in-depth interviews with school dieticians and nutrition teachers to determine the local foods they were aware of and their experiences with local foods. We also aimed to obtain more detailed measures for local food vitalization and suggestions for improvements. In-depth interviews were performed with 8 school dieticians and nutrition teachers, who stated that local food vitalization was needed for school food services, because it could be a foundation for securing safefood products, student healthi mprovements, environmental protection, and the establishment of a general consumption market. However, they were aware of a higher number of disadvantages than advantages in school situations and indicated the deterioration of the quality of food products as the biggest disadvantage. The most-suggested measurement items for local food vitalization in schools included improvement of the food distribution system, expansion of education, information sharing, prevention of monopolies, improvement of food-product quality, and mass production. In addition, it was suggested that school dieticians and nutrition teachers should invest efforts in the development of excellent recipes and varied diets utilizing local foods. Therefore, system supplementation is urgently required in order for school food service officials, and consumers, to efficiently introduce and vitalize local foods. It is also necessary to foster an environment that encourages trust-based relationships with producers to maximize the effect of system supplementation. This would be the foundation for improving the health of students, improving food-service quality, nutrition management, and vitalization of the regional economy in the future, and will positively affect students' food consumption patterns even after they become adults.

• 한국의류학회지
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• 제35권11호
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• pp.1285-1296
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• 2011

This study examines the effects of fashion and beauty consumption behavior on self-satisfaction. A questionnaire method was used for the study method and the subjects of the study were females in their 20s- 50s. A total of 580 sets of questionnaires were distributed and 554 sets were used for the final analysis; in addition, SPSS 12.0 statistics program was utilized for factor analysis, reliability analysis, correlation analysis, one-way ANOVA, Duncan test and multiple regression analysis. The results of this study were: First, the factors of fashion consumption behavior are composed of physical supplementation, social symbolism, appearance styling, sexuality and conformity and those of beauty involvement consisted of hair styling, skin management, make-up and body shaping. Self-satisfaction was divided into living satisfaction, appearance satisfaction, economic satisfaction and interpersonal relations satisfaction. Second, (because of the examination of the effects of fashion consumption behavior on self-satisfaction) fashion physical supplementation and appearance styling of fashion consumption behavior influenced living satisfaction and interpersonal relations satisfaction for females in their 20s. However, fashion consumption behavior did not influence satisfaction for those in their 30s. It was shown that the social conformity factor of fashion consumption behavior influenced appearance satisfaction of self- satisfaction for those in their 40s and the conformity factor of fashion consumption behavior gave a negative influence on life satisfaction and economic satisfaction of self-satisfaction for those in their 50s. It was found (for beauty consumption behavior) that the body-shaping factor influenced economic satisfaction and interpersonal relations satisfaction of self-satisfaction for all age levels.