• CELLMED
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• v.3 no.1
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• pp.9.1-9.10
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• 2013

In traditional systems of medicine including homeopathy, the Condurango extract (Con) is often used to cure stomach cancer mainly, without having any scientific validation of its anti-cancer ability. Con has therefore been tested against non-small-cell lung cancer cells (NSCLC) A549 and NCI-H522 (H522) known to contain the KRAS mutation, making them resistant to most chemotherapeutic agents. As cancer cells generally defy cytotoxicity developed by chemopreventive agents and escape cell death, any drug showing the capability of preferentially killing cancer cells through apoptosis is worth consideration for judicious application. A549 and H522 cells were exposed to $0.35{\mu}g/{\mu}l$ and $0.25{\mu}g/{\mu}l$ of Con, respectively, for 48 h and analysed based on various protocols associated with apoptosis and DNA damage, such as MTT assay to determine cell viability, LDH assay, DNA fragmentation assay, comet assay, and microscopical examinations of DNA binding fluorescence stains like DAPI, Hoechst 33258 and acridine orange/ethidium bromide to determine the extent of DNA damage made in drug-treated and untreated cells and the results compared. Changes in mitochondrial membrane potential and the generation of reactive oxygen species were also documented through standard techniques. Con killed almost 50% of the cancer cells but spared normal cells significantly. Fluorescence studies revealed increased DNA nick formation and depolarized membrane potentials after drug treatment in both cell types. Caspase-3 expression levels confirmed the apoptosis-inducing potential of Con in both the NSCLC lines. Thus, overall results suggest considerable anticancer potential of Con against NSCLC in vitro, validating its use against lung cancer by practitioners of traditional medicine including homeopathy.

• Journal of Advanced Navigation Technology
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• v.2 no.1
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• pp.53-60
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• 1998

This paper describes some design concepts and design parameters of RZ-SSB which allows full carrier insertion into the single side band to overcome the severe fading in aeronautical telecommunication, and it is described in ARINC Spec. in the name of AME(AM Equivalent), and the necessary transmission bandwidth of RZ-SSB is similar to that of a aeronautical telecommunication. As an amplitude limiter manage to remove the amplitude fading without degrading the quality of output signal, the receiver acts like the FM demodulators. Using the digital Signal Processing(DSP) techniques in the design of transceiver systems has become a performance enhancement of the signal quality and reliability, and making use of DSP, it's able to design low cost, compact transceiver and reduce its weight. For avionics systems is able to eliminate the inherent disadvantages in RZ-SSB, the results of experimental tests suggest that the adoption of RZ concepts is suitable for aeronautical telecommunication transceiver systems use in HF band.

• Conservation Science in Museum
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• v.20
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• pp.93-106
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• 2018

The musical instruments displayed in Korean Museums consist of various materials such as wood, stone, metal, leather, and soil. As for instruments manufactured of organic materials, as time passed, they became damaged due to physical, chemical and biological effects. In order to restore these instruments, studies on the materials as well as the manufacturing techniques should be simultaneously conducted because of the characteristics of sound making instruments. In this study, 17th century Double bass were chosen as the model for the restoration study. The type of wood was identified and the finishing layer was analyzed. To investigate the finishing layer, the surface observation was conducted and the component analysis was also conducted by using both FT-IR and SEM-EDS. As a result, the species of wood were identified as the maple trees. In case of the finishing layer of it, the diluted Goma Lacca, a type of resin, with alcohol as the main solvent was covered for varnishing layer. These results were combined to determine the restoration of Double bass Maggini Giovanni Paolo varnishing layer and by this Violin was made.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.9
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• pp.1153-1158
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• 2018

Online customer evaluations and social media information among a variety of information sources are critical for businesses as it influences the customer's decision making. There are limitations on the time and money that the survey will ask to identify a variety of customers' needs and complaints. The customer review data at online shopping malls provide the ideal data sources for analyzing customer sentiment about their products. In this study, we collected product reviews data on the smartphone of Samsung and Apple from Amazon. We applied five classification algorithms which are used as representative sentiment analysis techniques in previous studies. The five algorithms are based on support vector machines, bagging, random forest, classification or regression tree and maximum entropy. In this study, we proposed entropy score which can comprehensively evaluate the performance of classification algorithm. As a result of evaluating five algorithms using an entropy score, the SVMs algorithm's entropy score was ranked highest.

• The KIPS Transactions:PartD
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• v.12D no.4 s.100
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• pp.657-662
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• 2005

The Non-Sampling Error can happen any time by means of the intended or unintended error by the interviewer or respondent, but it is very difficult to find the error in survey database because it can hardly be computed mathematically and systematically. Until now, we have found it accidentally through the simple relation between the items or through the inspection from the random field. Therefore we introduced an heuristic methodology that can detect the interviewer's error by statistical decision-making or data mining techniques with a case study. It will be helpful so as to improve the statistical duality and provide efficient field management for the supervisor.

• The KIPS Transactions:PartD
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• v.12D no.4 s.100
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• pp.569-582
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• 2005

As information and business communication via Internet are growing up, web-based software is wide spread and more important on the viewpoint of software qualify than stand-alone. Research on verification of web content links and web-based Program was tried, but has short on covering various types of web based software and making experiments to be applied in real testing practice. This paper suggests a modeling technique to be applied to dynamic and various types of web-based software. First, it identifies each elements consisting of web-based software and then construct a model of Object Control Flow Graph and Object Relationship Diagram. We can generate test cases covering all test paths of ORD or invoking key points test route. Suggested modeling method and test case selection technique are verified by applying five types of web-based software and compared with other web-based test techniques.

• Journal of KIISE
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• v.42 no.4
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• pp.512-521
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• 2015

Internet users purchase goods on the Internet and express their positive or negative emotions of the goods in product reviews. Analysis of the product reviews become critical data to both potential consumers and to the decision making of enterprises. Therefore, the importance of opinion mining techniques which derive opinions by analyzing meaningful data from large numbers of Internet reviews. Existing studies were mostly based on comments written in English, yet analysis in Korean has not actively been done. Unlike English, Korean has characteristics of complex adjectives and suffixes. Existing studies did not consider the characteristics of the Internet language. This study proposes an emotional classification method which increases the accuracy of emotional classification by analyzing the characteristics of the Internet language connoting feelings. We can classify positive and negative comments about products automatically using the Internet emoticon. Also we can check the validity of the proposed algorithm through the result of high precision, recall and coverage for the evaluation of this method.

• Journal of Korean Society for Geospatial Information Science
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• v.11 no.3 s.26
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• pp.55-63
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• 2003

Korean cadastral system is primarily based on the graphical maps, thus, map reproduction by excessive shrinkage or extension, map mishandling and imperfection of surveying techniques have created cadastral non-coincident areas, which caused public distrust as well as considerable difficulties in land administration and policy making. Therefore, in this study, the methodologies for the resolution of the non-coincident problem are presented by means of a comparative analysis between cases of the non-coincident areas. The non-coincidence caused by the mismatch of parcel boundaries can be settled by introducing a coordinate-based system namely ${\ulcorner}$Integrated Land Information System${\lrcorner}$, meanwhile, those by other reasons can be done by establishing and executing a plan that can deliver the unification of the cadasoal and the land registration systems. Governmental intention and budgetary measures for securing the project expenses are essential to make this feasible. If the comprehensive improvement project is completed, the cadastral registers that define the parcel boundary, area and ownership will recover public confidence, which in turn secures land owners' rights by promoting land markets and stabilizing land prices.

• Journal of Conservation Science
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• v.30 no.1
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• pp.81-93
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• 2014

As the Seated Iron Buddha Statues, Vairocana Buddha of Dopiansa Temple in Cheolwon, Nosana Buddha of Samhwasa Temple in Donghae and Sakyamuni of Mangisa Temple in Pyeongtaek were made during Unified Silla to Koryo Dynasty. These are damaged degradation which are crack, break-out, peel off and various pollutant. As a result of deterioration evaluation using radiography, crack, gap, break-out, pore space and restoration material are confirmed inside in the Buddha Statues. Based on iron strength, the Buddha Statues will be maintain current state as long as a high external impact is not applied. Also, iron core and nails used for fixing of internal and external framework were observed in the Buddha Statues. According to prominent line of surface, embossed inscription, hands cast separately and combined, the Buddha Statues were made by using division casting.

• Journal of the Korean Association of Geographic Information Studies
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• v.11 no.2
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• pp.1-12
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• 2008

This paper identifies public transit-poors and derives spatial characteristics of the poors' distribution in an urban area by utilizing buffering analysis of geographic information systems and remote sensing techniques in the case of Daegu metropolitan city. Since special attention is given to elderlies, this study assigns three hundred meter buffer from bus/subway station as service boundary for elderlies. The results of this study tell us that 1) the transit-poors are concentrated on suburban and rural regions, 2) high proportions of the transit poors are elderlies with spatial variations in many regions, 3) the main housing type of the transit-poors is single detached house. We expect that this study can contribute to build an effective policy-making by showing essential technical processes and methods in identifying policy-need groups and their characteristics of spatial distribution.