• Asian Pacific Journal of Cancer Prevention
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• v.16 no.1
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• pp.253-258
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• 2015

Background: Development of squamous cell cancer of head and neck (SCCHN) is associated with human papillomavirus (HPV) infection, which in turn is closely related with expression of $p16^{INK4A}$. Loss of $p16^{INK4A}$ expression by deletion, mutation, or hypermethylation is common in SCCHN. We here evaluated $p16^{INK4A}$ as a prognostic marker of treatment response and survival in our SCCHN patients with laryngeal, hypopharyngeal or nasopharyngeal cancers. Materials and Methods: 131 patients diagnosed with SCCHN between January 2,2006 and July 17, 2010 were examined for $p16^{INK4A}$. The median age was 60 years (15-82 years). Fifty one patients were stage I-II and 80 were stage III-IV. Immunohistochemical expression of $p16^{INK4A}$ was analyzed in pretreatment paraffin-embedded tumor blocks. The influence of $p16^{INK4A}$ status on disease-free survival, and overall survival after treatment was evaluated. Results: $p16^{INK4A}$ positivity was found in 58 patients (44%). Tumor-positivity for$ p16^{INK4A}$ was correlated with improved disease free survival (70.1 months vs 59 months) and improved overall survival (2, 3 and 5-year values; 77% vs 72%, 70% vs 63% and, 63% vs 55%; respectively). On multivariate analysis, stage was determined as independent prognostic factor for disease-free survival. Conclusions: Stage was the major prognostic factor on treatment response and survival in our patients. $p16^{INK4A}$ status predicts better outcome in laryngeal, hypopharyngeal or nasopharyngeal cancer cases treated with surgery plus adjuvant radiochemotherapy as well as with definitive radiation therapy and/or chemotherapy.

• Journal of the Korean Geographical Society
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• v.39 no.2
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• pp.229-240
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• 2004

This article aimed to suggest a program for environmental protection and sustainable development in southwest Primorskii Krai of the Russian federation by analysis of Natural conditions, natural resources and current economic activities. Issues relating to protecting unique biodiversity toward economic development are examined. Special attention is given to functional zoning of the Russian part of lower Tumen River drainage. Functional zoning is key to protecting the unique biodiversity found in wet and marshlands of the lower Tumen River. Recommendations for acceptable economic activity are provided. The major components for a Sustainable Development Program in this area are: to define economically effective and ecologically acceptable types of regional activity (aquaculture; deer farming; recreation) and effective forms of territorial organization; to determine the restrictions on regional industrial and economic development; to organize rational regional land use by carrying out functional zoning and by coordinating this activity with all land users, including restructuring existing protected territories into a single system and include it into an international biospheric network.

• Journal of The Korean Association For Science Education
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• v.39 no.1
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• pp.59-72
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• 2019

The purpose of this study is to show that epistemic considerations can be used meaningfully in the argumentation of elementary students, and to provide data on students' epistemic considerations that will be the basis for designing and evaluating scientific argumentation. The epistemic considerations in students' small group argumentations were explored based on Epistemic Considerations in Students' Epistemologies in Practice: EIP' suggested by Berland et al. (2016). The major results of this study are as follows: First, epistemic considerations in elementary school students' small group argumentation appeared in all four aspects: Nature, generality, justification and audience. The epistemic considerations varied according to context in each discussion situation. Second, epistemic considerations did not exist independently. They influenced each other and helped to reveal new types of considerations. The results of this study confirmed that argumentation can be used in elementary school science class. Understanding how students are involved in argumentation and how these epistemic considerations can affect students' argumentation can be helpful to teachers who design and evaluate small group argumentation. Students' achievement level affected epistemic considerations but learning approach types did not affect on. In addition, epistemic considerations may have a positive or negative effect on each other depending on the discussion situation in the process of interaction. So consideration of normative argumentation rules and teaching strategies should be considered in order for epistemic considerations to positively affect each other.

• Journal of Marine Life Science
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• v.4 no.2
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• pp.91-95
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• 2019

The changes of plasma cortisol concentration to high water temperature on common carp, Cyprinus carpio were studied. 20℃, 24℃ and 28℃ groups showed significantly increased plasma cortisol levels until 6 hours, and decreased plasma cortisol levels after 24 hours. Cortisol levels of 20℃ and 24℃ groups decreased to values close to the cortisol content before the experiment. However, 32℃ group showed significantly increased plasma cortisol levels until 24 hours, and maintained plasma cortisol level until 48 hours. The Cumulative mortality rates of 20℃, 24℃ and 28℃ groups increased until 12 hours, and maintained until 48 hours. Cumulative mortality rate of 32℃ group increased continuously until the end of the experiment. Using the results of this study, it could be used as a method to confirm the risk of mass perish in a specific area through hormone analysis.

• Journal of Preventive Medicine and Public Health
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• v.38 no.1
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• pp.16-24
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• 2005

Objectives : To help develop strategies to cope with the changes arising from the rapid aging process by predicting the determining factors of intention to actual use of the charged long-term care services for elderly as perceived by the middle aged who play the major role of supports. Methods : Subjects were the parents (men 177, women 507) in their 40s of the students selected from a university of Busan city. A questionnaire survey was conducted for 4 weeks in October 2003 about the knowledge for long-term care service, the intention of actual use, and the preferences about the type of service suppliers. Data analysis was performed with frequency, chi-square test, and t-test using SPSS program (ver 10.0K), along with data mining using decision tree of Enterprise Miner V8.2 by SAS. Results : About half of the subjects (53.7%) had the actual experiences of elderly supports. Intentions to use the charged services were relatively high in home visiting nursing care service (40.1%) and long-term care facilities service (40.4%), and were influenced by previous knowledge about the services. The intentions were stronger in women, those with higher education, and those with greater income levels. Actual elderly supports were mostly (80%) done by women, and the perceived burdens for the supports were bigger in women and those of lower socioeconomic level. Desired charges were about 10,000 won for the bath service, 20,000 won for the rests services per day, and about 500,000 won for the long-term care facilities service per month. From the result of decision tree analysis, the job professionalism was the most important determining factor of intention to actual use of the services with validation as $63{\sim}71%$. Health and welfare mixed type facilities were preferred, and the most important consideration was the level of professionalism. Conclusions : Intention to actual use of the charged services was largely determined by the aspects of time and cost. Polices to increase the number of service suppliers and to decrease the burdens perceived by actual supporters were strongly recommended.

• Journal of Environmental Science International
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• v.25 no.7
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• pp.1017-1028
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• 2016

Wind information is one of the major inputs for the prediction of urban air flow using computational fluid dynamic (CFD) models. Therefore, the numerical characteristics of the wind data formed at their mother domains should be clarified to predict the urban air flow more precisely. In this study, the formation characteristics of the wind data in the Seoul region were used as the inlet wind information for a CFD based simulation and were analyzed using numerical weather prediction models for weather research and forecasting (WRF). Because air flow over the central part of the Korean peninsula is often controlled not only by synoptic scale westerly winds but also by the westerly sea breeze induced from the Yellow Sea, the westerly wind often dominates the entire Seoul region. Although simulations of wind speed and air temperature gave results that were slightly high and low, respectively, their temporal variation patterns agreed well with the observations. In the analysis of the vertical cross section, the variation of wind speed along the western boundary of Seoul is simpler in a large domain with the highest horizontal resolution as compared to a small domain with the same resolution. A strong convergence of the sea breeze due to precise topography leads to the simplification of the wind pattern. The same tendency was shown in the average vertical profiles of the wind speed. The difference in the simulated wind pattern of two different domains is greater during the night than in the daytime because of atmospheric stability and topographically induced mesoscale forcing.

• Journal of the Korean Society of Clothing and Textiles
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• v.29 no.9_10 s.146
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• pp.1265-1273
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• 2005

The objective of this study is to examine the images of the current uniforms and to provide the basic references in designing female flight attendants uniforms. In Incheon International Airlines, 11 of the major airlines with the most passengers along with the highest capacity were chosen and 22 pieces of photographs were collected, two photos coming from each airline companies. The semantic differential scale has been formed by 16 pairs of adjectives. Then, it has conducted a statistical analysis using a SPSS WINDOWS that contains 475 copies of the selected questionnaires (375 of the non-flight attendants, and 100 of the female flight attendants). The following are the results and the conclusion of this study. According to this study, four main components of the uniforms of the female flight attendants were attractiveness, femininity, noticeability, and activity, which have occupied $65.9\%$ of the total variance. It was concluded that attractiveness and femininity were two main factors in perceiving the females' uniforms. According to the results of the uniform image difference, it was shown that Asiana Airline's uniform is the most attractive and Cathay Pacific Airline uniform is the most feminine. The most noticeable uniform was from Singapore airline which included cultural and traditional components of its own national colors. Pants suits of Lufthansa airline and Northwest airline were shown as the most active uniforms. There were significant differences in uniform images according to subjects' gender, age, education, and occupation. Men perceived uniforms more attractive, feminine, and active than women. People over 40 perceived uniforms more attractive, feminine, and active, and the High School graduates perceived uniforms more feminine and active. On occupational basis, Federal workers and Educators perceived uniforms more active on uniforms. Passengers who take planes once a month perceived uniforms more attractive, feminine, and active.

• 재활복지
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• v.20 no.3
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• pp.83-104
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• 2016

The purpose of this study was to identify improvement in locomotor skills by physical activity programs. Method of this study indicates that the current literature (2004-2015) were reviewed and the data from 24 studies with 518 disabled children were analyzed by using CMA3 (Comprehensive Meta-Analysis ver.3) program. Analyzing the data of the primary studies included gender, age, type of disabilities, duration of the physical activity program intervention(weeks, session per week, minutes per session), run, gallop, hop, leap, horizontal jump, and slide. For sensitivity analysis, publication bias and outlier were reviewed. Results of analysis indicates that the overall effect size of improvement in locomotor skills by physical activity programs was 1.143. There were large effect size in categorical analyses. Autistic spectrum among type of disabilities was 1.697 and run among 6 of locomotor skills was 1.019. 8~10 aged was 0.920 and the intervention of 100~120minutes(1.261)per session, 3sessions(1.078) per week, 16~20(1.587)weeks was found to be more larger than the others. In conclusion, improvement in locomotor skills by program participation showed that treated group was 37% more effective than control group.

• Korean Journal of Applied Biomechanics
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• v.21 no.3
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• pp.317-325
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• 2011

The purpose of this study was to investigate the contributions of body joints to the kinetic energy of the clubhead in the golf swing. Three dimensional swing analysis was conducted on the seven KPGA golfers. The subjects were asked to swing with 45 inches of driver. The work done by body joints were computed by utilizing the inverse dynamics method. The order of work done by the body joints was lumbar > left hip > right shoulder > left wrist > right wrist > right hip at the first phase. At the second phase, the order of work done by the body joints was trunk > left elbow > right wrist > right shoulder > left wrist > right wrist. At the third phase, the order of work done by body joints was lumbar > right shoulder > left shoulder > left elbow > right wrist > right elbow. The sum of the work done by the body joints was lumbar > shoulder > wrist on the average. The kinetic energy of the club head was 430.11${\pm}$24.35 J and the subject's swing efficiency was shown as 31.82${\pm}$4.86% on the average. The contributions of body joints to the kinetic energy of the clubhead was the order of lumbar > upper right shoulder > left elbow > right wrist during the down swing.

• Journal of Digital Convergence
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• v.11 no.11
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• pp.621-631
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• 2013

This study aimed to investigate that what factors affect the volunteer activities of dental hygiene students and present a plan and problems with devising a program for activating their volunteer activities. A self-administered questionnaire survey was conducted in 265 dental hygiene students in Gwangju from November to December 2012, obtaining the following results: 51.3% of the respondents were freshmen; 74.3% had experience of volunteer activities; and 31.7% had the activities in the field of disabilities. 56.2% were motivated to participate in the activities by 'credit-earning and volunteer activity achievements'. Most of students participated in volunteer activities through clubs. Satisfaction with major-related volunteer activities was associated with higher support by others, higher job perception, higher job adequacy, and higher support by family. To increase satisfaction with major-related volunteer activities of students research is needed to develop systematic education for volunteers, subjects suitable for colleges, and an effective program in order to alter students' perception.