• Title/Summary/Keyword: main agent of research

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Inference of Aspergillus fumigatus Pathways by Computational Genome Analysis: Tricarboxylic Acid Cycle (TCA) and Glyoxylate Shunt

  • Do, Jin-Hwan;Anderson, Michael-J.;Denning, David-W.;Erich, Bornberg-Bauer
    • Journal of Microbiology and Biotechnology
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    • v.14 no.1
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    • pp.74-80
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    • 2004
  • Aspergillus fumigatus is one of the most common fungi in the human environment, both in-doors and out-doors. It is the main causative agent of invasive aspergillosis, a life-threatening mycosis among immunocompromised patients. The genome has been sequenced by an international consortium, including the Wellcome Trust Sanger Institute (U.K.) and The Institute for Genomic Research (TIGR, U.S.A.), and a ten times whole genome shotgun sequence assembly has been made publicly available. In this study, we identified tricarboxylic acid (TCA) cycle enzymes of A. fumigatus by comparative analysis with four other fungal species. The open reading frames showed high amino acid sequence similarity with the other fungal citric acid enzymes and well-conserved functional domains. All genes present in Saccharomyces cerevisiae, Schizosaccharomyces pombe, Candida albicans, and Neurospora crassa were also found in A. fumigatus. In addition, we identified four A. fumigatus genes coding for enzymes in the glyoxylate shunt, which may be required for fungal virulence. The architecture of multi-gene encoded enzymes, such as isocitrate dehydrogenase, 2-ketoglutarate, succinyl-CoA synthetase, and succinate dehydrogenase was well conserved in A. fumigatus. Furthermore, our results show that genes of A. fumigatus can be detected reliably using GlimmerM.

Recovery of Ammonium Salt from Nitrate-Containing Water by Iron Nanoparticles and Membrane Contactor

  • Hwang, Yu-Hoon;Kim, Do-Gun;Ahn, Yong-Tae;Moon, Chung-Man;Shin, Hang-Sik
    • Environmental Engineering Research
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    • v.17 no.2
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    • pp.111-116
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    • 2012
  • This study investigates the complete removal of nitrate and the recovery of valuable ammonium salt by the combination of nanoscale zero-valent iron (NZVI) and a membrane contactor system. The NZVI used for the experiments was prepared by chemical reduction without a stabilizing agent. The main end-product of nitrate reduction by NZVI was ammonia, and the solution pH was stably maintained around 10.5. Effective removal of ammonia was possible with the polytetrafluoroethylene membrane contactor system in all tested conditions. Among the various operation parameters including influent pH, concentration, temperature, and contact time, contact time and solution pH showed significant effects on the ammonia removal mechanism. Also, the osmotic distillation phenomena that deteriorate the mass transfer efficiency could be minimized by pre-heating the influent wastewater. The ammonia removal rate could be maximized by optimizing operation conditions and changing the membrane configuration. The combination of NZVI and the membrane contactor system could be a solution for nitrate removal and the recovery of valuable products.

Does Public Diplomacy Need a Theory of Disruption? The Role of Nonstate Actors in Counter-branding the Swedish COVID-19 Response

  • Pamment, James
    • Journal of Public Diplomacy
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    • v.1 no.1
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    • pp.80-110
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    • 2021
  • Public diplomacy (PD) scholars tend to consider two main principals: the country or agent that conducts PD (Actor A), and target groups in the host country in which PD is conducted (Actor B). The field currently lacks theories of how communications between Actors A and B can be disrupted by a third party, such as a group of motivated trolls, an organised advocacy group, or a hostile country and its agents. The purpose of this article is to outline some theoretical considerations for how the PD research field might move away from a two-actor model of PD to one in which disruption is part of the discussion. The case study explores the activities of an interest group called Media Watchdogs of Sweden (MEWAS). MEWAS was a group of around 200 members who met in a hidden Facebook group to coordinate off-platform activities aimed at influencing perceptions of how the Swedish government handled the COVID-19 pandemic in the eyes of foreign governments, researchers, decision-makers, and media. Much critical news coverage in the international press has been linked to this group. Unpacking some of MEWAS' activities, which can be considered a quite typical mixture of legitimate and illegitimate communication techniques used by activist groups, can help to shed light on some difficult questions regarding disruption in PD.

De-colonialism and the Collection Study - Research on Bias of Library Collection with Reference to History of Social Thoughts (탈식민주의 글쓰기와 장서 연구 -도서관 장서의 편향성에 관한 사회사상사적 접근)

  • Kim Young-Gi
    • Journal of Korean Library and Information Science Society
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    • v.36 no.1
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    • pp.173-193
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    • 2005
  • The modern society is one of knowledge and information, and the library is one of the important routes through which they are obtained. But the collection in the library, from the onset of its creation and the process of accumulation, could only be bent and biased due to the prejudice and distortion, inevitably acting as an agent that mires the essence of the library as a distribution channel for knowledge and information of modern society. This study is the discussion about the necessity, main assignment and the methodology of library collection study. The collection study needs to focus on the process of accumulating the collection in the library to track down the Process of becoming biased.

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A Study on the Futurist Manifestos and Clothing in Italy (이탈리아의 미래주의 복식 선언문과 그 복식연구)

  • Keum Hee Lee
    • The Research Journal of the Costume Culture
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    • v.8 no.1
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    • pp.102-114
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    • 2000
  • The works of the Futurism were developed along with manifestos and statement in publishing. Futurist aesthetic and ideological agenda on futurist fashion displayed in manifestos on clothes. Futurist fashion propagated in consummate Futurist style through the written manifesto. The Futurists anticipated much of modern fashion phenomenon. In Futurist Men's Clothing, men's clothing is aggressive, agile, dynamic, simple and comfortable, hygienic, gay, luminous, volatile, asymmetric and variable. In Futurist Manifesto on Woman's Clothing, woman is now a principal agent of revolt, a walking synthesis of the audacious, performance-oriented aesthetic of the futurist universe. For Futurist woman's clothing they claimed ingenuity, daring, and economy. The Futurist Manifesto of Italian Hat was continued with their provocative style and radical ambition. Their innovation will rescue a lagging Italian expert and restore the Italian male to his former Iatin Vigor. Speed, dynamic, utility, and funtionality are the main characters. In Futurist Manifesto of Italian Cravat, Futurist cravat is called Anti-cravatta, which is anti-traditional style and made of unconventional materials. In general, the Futurist argued for clothes that promoted simple and functionality. These Futurist fashion project were invention of the new style, avant-garde style, in daily wear and were realized for the renewal of taste in clothing design as a modernizing factors.

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The Combustion Characteristics of a Subscale Engine of KSRIII(I) (KSR-III 엔진 축소형 모델 연소 특성(I))

  • Kim, Young-Han;Kim, Yong-Wook;Ko, Young-Sung;Lee, Soo-Yong;Ryu, Chul-Song;Seol, Woo-Seok
    • Proceedings of the KSME Conference
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    • 2001.06d
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    • pp.846-851
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    • 2001
  • For the successful development of the main engine of KSR(Korea Sounding Rocket)-III, Korea Aerospace Research Institute(KARI) carried out the experimental study on the subscale model engines. Several types of engines were tested on the Small Liquid Rocket Engine Test Facility. One of the typical test results of a Sub. engine(Sub. Mod.3) is presented here. It uses the Jet A-1 as fuel, liquid oxygen as oxidizer, and Tri-Ethyl Aluminium(TEA1) as ignition agent. The gas pressure feed system is adopted as a feeding mechanism and the design chamber pressure is 200psia. The physical phenomena are described in three regimes(ignition, transient, and steady state) with the pressure, thrust, flowrate and image data. And the pressure oscillation is analyzed in Fourier domain (<500Hz). Then we conclude that in this experiment, the engine shows the characteristic low frequency of 80Hz and it is stable for that frequency of pressure oscillation.

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A Study on Dusting of Formed Concrete Surface (목제(木製)거푸집 사용으로 콘크리트표면(表面)에 발생(發生)하는 경화불량현상(硬化不良現象)에 대한 연구(研究))

  • Moon, Han Young;Choi, Jae Jin
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.3 no.2
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    • pp.73-85
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    • 1983
  • We occasionally find a thin layer of imperfectly hardened concrete surface when the wood form is stripped off. It has been generally believed that the principal causes were the effects of reactive form oil, adhesive agent or formalin which has been used in the course of plywood manufacturing. However, in this experiment, it became clear that the concrete surface could be influenced more harmfully by a certain species of wood form and the storage conditions of wood form rather than any other causes. Especially, the main cause of the severely dusty layer is the use of wood form exposed to sun for a long period. Countermeasures, therefore, for preventing concrete surface from dusting are also discussed in this paper.

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The Identity of Eggplant Powdery Mildews Collected in Korea (한국에서 채집된 가지 흰가루병균의 실체)

  • Cho, Sung-Eun;Choi, In-Young;Shin, Hyeon-Dong
    • The Korean Journal of Mycology
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    • v.45 no.2
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    • pp.91-101
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    • 2017
  • Three species of powdery mildew (Erysiphales) on eggplant (Solanum melongena L.) have been listed in Korea, namely Erysiphe cichoracearum (now genus Golovinomyces), Leveillula taurica, and Sphaerotheca fusca (now genus Podosphaera; syn. Podosphaera xanthii). Since E. cichoracearum was recorded on eggplant for the first time in Korea in 1969, it has been regarded as a major powdery mildew agent on that plant. In 1998, the causal agent of powdery mildew on eggplant was recorded as L. taurica, then as S. fusca in 2002. During our extensive field surveys in Korea, we collected 22 samples of eggplant powdery mildews. Our microscopic observations and molecular sequence analyses showed that all of our samples belonged to the genus Podosphaera, in the absence of either E. cichoracearum or L. taurica, suggesting that P. xanthii is the dominant agent of powdery mildew disease on eggplants in Korea. As there have been no additional findings on L. taurica after the first report on the species, it seems to be a minor species that is rarely found in greenhouses. The presence of E. cichoracearum (syn. Golovinomyces cichoracearum s. lat.) on eggplants is questionable, as the morphological characteristics of E. cichoracearum in the original description of the Korean collection deviate from the morphological variations of this species. In addition, no herbarium material of E. cichoracearum remains. Consequently, it seems that P. xanthii is the main species of powdery mildew on eggplants, whereas L. taurica occurs rarely on eggplants, in Korea. This review provides the historical and recent taxonomy of eggplant powdery mildews in detail.

A Study on the Use of Facet Analysis for Ontology Modeling (온톨로지 모델링에서 패싯 분석 활용 연구)

  • Park, Heejin;Yi, Myongho;Kim, Seonghun;Oh, Sam Gyun
    • Journal of Korean Library and Information Science Society
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    • v.46 no.2
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    • pp.257-287
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    • 2015
  • This study proposes a methodology for using facet analysis in ontology modeling and investigates how facet analysis could be utilized in ontology design processes. We applied facet analysis methods developed by Ranganathan and CRG (Classification Research Group) to modeling Smartphone ontology. Utilizing the guiding principles of Ranganathan and CRG, main facets, such as Type, Spec, Function, Operation, Product, Person, Agent, Space and Time, are derived for Smartphone ontology. It is hoped that the methods and procedures employed in identifying and categorizing facets and ontology in this study will provide insights into designing future ontologies.

Developing a New Algorithm for Conversational Agent to Detect Recognition Error and Neologism Meaning: Utilizing Korean Syllable-based Word Similarity (대화형 에이전트 인식오류 및 신조어 탐지를 위한 알고리즘 개발: 한글 음절 분리 기반의 단어 유사도 활용)

  • Jung-Won Lee;Il Im
    • Journal of Intelligence and Information Systems
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    • v.29 no.3
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    • pp.267-286
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    • 2023
  • The conversational agents such as AI speakers utilize voice conversation for human-computer interaction. Voice recognition errors often occur in conversational situations. Recognition errors in user utterance records can be categorized into two types. The first type is misrecognition errors, where the agent fails to recognize the user's speech entirely. The second type is misinterpretation errors, where the user's speech is recognized and services are provided, but the interpretation differs from the user's intention. Among these, misinterpretation errors require separate error detection as they are recorded as successful service interactions. In this study, various text separation methods were applied to detect misinterpretation. For each of these text separation methods, the similarity of consecutive speech pairs using word embedding and document embedding techniques, which convert words and documents into vectors. This approach goes beyond simple word-based similarity calculation to explore a new method for detecting misinterpretation errors. The research method involved utilizing real user utterance records to train and develop a detection model by applying patterns of misinterpretation error causes. The results revealed that the most significant analysis result was obtained through initial consonant extraction for detecting misinterpretation errors caused by the use of unregistered neologisms. Through comparison with other separation methods, different error types could be observed. This study has two main implications. First, for misinterpretation errors that are difficult to detect due to lack of recognition, the study proposed diverse text separation methods and found a novel method that improved performance remarkably. Second, if this is applied to conversational agents or voice recognition services requiring neologism detection, patterns of errors occurring from the voice recognition stage can be specified. The study proposed and verified that even if not categorized as errors, services can be provided according to user-desired results.