• IMMUNE NETWORK
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• v.3 no.1
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• pp.53-60
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• 2003

Background: The role of macrophages in tumor angiogenesis is known to be the production of angiogenic cytokines and growth factors including TNF-${\alpha}$. Recently, macrophage also can produce the INF-${\gamma}$ that is being studied to be involved in angiogenic inhibition. Thus, the importance of macrophages in tumor angiogenesis is might being an angiogenic switch. Thus, the hypothesis tested here is that TNF-${\alpha}$ can modulate the INF-${\gamma}$ production in the macrophages from tumor environment as a part of tumor angiogenic switch. Methods: Macrophages in tumor environment were obtained from the peritoneal cavity of C57BL/6 mice injected with B16F10 melanoma cell line for 6 or 11 days. $Mac1^+$-macrophages were purified using magnetic bead ($MACs^{TM}$; Milteny Biotech, Germany) and cultured with various concentrations of TNF-${\alpha}$ for various time points at $37^{\circ}C$. The supernatants were analyzed for IFN-${\gamma}$ or VEGF by ELISA kit (Endogen, Woburn, MA). Results: Residential macrophages from the peritoneal cavity did not respond to LPS or TNF-${\alpha}$ to produce INF-${\gamma}$. However, the cells from tumor environment produced IFN-${\gamma}$ as well as VEGF and upregulated by the addition of LPS or TNF-${\alpha}$. RT-PCR analysis revealed the external TNF-${\alpha}$-induced IFN-${\gamma}$ gene expression in the macrophages from tumor environment. Conclusion: The overall data suggest that the macrophages in tumor environment might have an important role not only in angiogenic signal but also in anti-angiogenic signal by producing related cytokines. And TNF-${\alpha}$ might be a key cytokine in tumor angiogenic switch.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.8
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• pp.1125-1131
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• 2013

Wireless power transmission technology has been studied variety. Recently, wireless power transmission technology used by resonance and magnetic induction field is applied to various fields. However, magnetic resonance and inductive coupling are have drawbacks - power transmission distance is short. Microwave transmission and accept techniques have been developed to overcome short distance. However, improvement in efficiency is required. This paper, propose a high-efficiency microwave energy acceptor IC(EAIC). Suggested EAIC is consists of RF-DC converter and DC-DC converter. Wide Input power range is -15 dBm ~ 20 dBm. And output voltage is boosted up to 5.5 V by voltage boost-up circuit. EAIC can keep the output voltage constant. Available efficiency of RF-DC converter is 95.5 % at 4 dBm input. And DC-DC efficiency is 94.79 % at 1.1 mA load current. Fully EAIC efficiency is 90.5 %.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.51 no.8
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• pp.434-440
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• 2002

Switched Reluctance Motor (SRM) has been not commonly used because of the severe noise and vibration, although it has many advantages as solidity and economical efficiency. The origin of the acoustic noise and vibration in SRM's can be broadly classified into two types, mechanical and magnetic. Therefore this paper verifies the origin of vibration induced by radial magnetic forces from various experiments, and then studies the relationship between the output and vibration characteristics of SRM according to switch-on and off angles. Acceleration, torque and efficiency is measured by changing switching angles. From the comparison and analysis of the experimental results, a proper switching angle is presented for both satisfying electric performance and reducing vibration.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.55-55
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• 2010

We use ab initio density functional theory to determine the effect of bundling on the equilibrium structure, electronic and magnetic properties of $Mo_6S_{9-x}I_x$nanowires with x = 0, 3, 4.5, 6. Each unit cell of these systems contains two $Mo_6S_{6-x}I_x$ clusters connected by S3 linkages to form an ordered linear array. Due to the bi-stability of the sulfur linkages, the total energy of the nanowires exhibits typically many minima as a function of the wire length. We find that nanowires can switch over from metallic to semiconducting by applying axial stress. Structural order is expected in bundles with x=0 and x=6, since there is no disorder in the decoration of the Mo clusters. In bundles with other stoichiometries, we expect structural disorder to occur. We find the optimum inter-wire distance to depend sensitively on the orientation of the wires, but only weakly on x. It is also found that the electronic properties of nanowires are affected strongly due to bundling of nanowires exhibiting very unusual Fermi surfaces. Furthermore, ferromagnetic behaviors are observed in selected stable and many more unstable atomic arrangements in nanowire bundles.

• Proceedings of the KIPE Conference
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• 2015.11a
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• pp.95-96
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• 2015

In this paper, a single-sourced PV PCS using the trinary asymmetric MLI with a single-ended pre-regulator is proposed. Trinary based asymmetric CHB inverters provide higher output levels for the same number of cells compared to other CHB inverters. However, there is an issue of regeneration with trinary asymmetric inverters and this complicates the system with requirement of bi-directional converters at the input. Modified commutation strategies have been used to remove the regeneration issue with compromise in THD. The single-ended pre-regulator provides the isolated dc-link voltage for the individual H-bridge cells with the advantage of having a single switch and magnetic component. This implementation increases the magnetic utilization of the inductor core and reduces the switching loss in the pre-regulator and also the reduced parts count contributes to the cost competiveness of the proposed PCS. The proposed PV PCS has been verified using simulation results in this paper.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.12
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• pp.85-91
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• 2021

In our daily life, artificial intelligence performs simple and complicated tasks like us, including operating mobile phones and working at homes and workplaces. Artificial intelligence is used in industrial technology for diagnosing various types of equipment using the machine learning technology. This study presents a fault mode effect analysis (FMEA) of start motors using machine learning and big data. Through multiple data collection, we observed that the primary failure of the start motor was caused by the melting of the magnetic switch inside the start motor causing it to fail. Long-short-term memory (LSTM) was used to diagnose the condition of the magnetic locations, and synthetic data were generated using the synthetic minority oversampling technique (SMOTE). This technique has the advantage of increasing the data accuracy. LSTM can also predict a start motor failure.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.3
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• pp.729-736
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• 2010

In this study, a magnetic stimulation (MS) device with controllable pulse forming technology and pulse shape (MS) is described. The MS device uses an IGBT with appropriate snubbers to switch coil currents up to 6 kA, enabling pulse forming technology control from 5 s to over 100 s. The induced electric field pulses use 2% - 34% less energy and generate 57% - 67% less coil heating compared to matched conventional cosine pulses. MS is used to stimulate rhesus monkey motor cortex in vivo with pulse forming technology of 20 to 100 s, demonstrating the expected decrease of threshold pulse amplitude with increasing pulse forming technology. The technological solutions used in the MS prototype can expand functionality, and reduce power consumption and coil heating in MS, enhancing its research and therapeutic applications.

• Analytical Science and Technology
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• v.29 no.5
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• pp.225-233
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• 2016

The chemical engrafting of polymers on particle surface, plays an important role on selective partitioning of micro/nano-particles in the separated layers of liquid media, such as aqueous two phase systems (ATPSs). Three polymers, dextran, poly (ethylene glycol) and albumin were chosen and chemically conjugated to the polystyrene (PS) magnetic microparticle surface. The attachment of long-chained polymer chains which may switch the partition behavior, can be simply performed by S_N2 substitution of various polymers having primary amine functional groups, with p-toluenesulfonyl (tosyl)-activated polystyrene magnetic micro-particles. The surface modification of microparticle was probed by infrared microscopy. The distinctive peak represents N-H stretching vibration mode for microparticles after the reaction and it is common for all three polymers examined. The locations of main peaks are similar for all micro-particles but different and distinguishable in fingerprint region.

• Proceedings of the KIEE Conference
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• 2002.07b
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• pp.888-890
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• 2002

We derived a theory of increasing electromagnetic force acting on arc column for reducing arcing time between electric contacts. A simulation method of arc velocity is presented by calculating blowout force using 3D FEM and drag acting on arc column. This paper is proposed 3 types arc extinguish chamber of different fulx path and is presented electromagnetic force and arc velocity of each model.

• Proceedings of the KIPE Conference
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• 2008.06a
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• pp.391-393
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• 2008

A modified boost converter with magnetic coupling is presented to reduce the reverse recovery loss while maintaining low conduction loss of the rectifiers. By utilizing a coupled inductor and a set of diodes, the current passing the boost rectifier is transferred to an auxiliary loop before turn-off, allowing low di/dt for reduced recovery loss. Moreover, the boost inductor is brought inside the bridge rectifier to reduce conduction loss by decreasing the number of conducting diodes during switch turn-off. Experimental results of a 500W prototype are provided to verify the increase in efficiency and validity of the proposed converter.