• Title/Summary/Keyword: macro cell

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Design of a Low Power High Speed Conditional Select Adder/Subtracter for Next Generation ASIC Library (차세대 ASIC 라이브러리를 위한 고속 저전력 조건 선택 덧셈기/뺄셈기의 설계)

  • Cho, Ki-Seon;Song, Min-Kyu
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.11
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    • pp.59-66
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    • 2000
  • As multimedia applications become popular, computers increasingly require high-speed DSP for 3-DIM computer graphic. In this Paper, a Macro-cell Library of conditional select adder/subtracter is proposed for DSP within high speed and low power consumption. Using, this design method, we are able to obtain an auto generation of the adder or(and) subtracter from 8-bit to 64-bit. The proposed adder/subtracter has been fabricated with a 0.25${\mu}m$, single-poly, five-metal, N-well CMOS technology. From the experimental results, delay time is 3.43ns, and the power consumption is 42.8${\mu}w$/MHz at the input frequency of 50MHz, at 2.5V single power supply, in case of the 32-bit adder/subtracter.

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Microchips and their Significance in Isolation of Circulating Tumor Cells and Monitoring of Cancers

  • Sahmani, Mehdi;Vatanmakanian, Mousa;Goudarzi, Mehdi;Mobarra, Naser;Azad, Mehdi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.879-894
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    • 2016
  • In micro-fluid systems, fluids are injected into extremely narrow polymer channels in small amounts such as micro-, nano-, or pico-liter scales. These channels themselves are embedded on tiny chips. Various specialized structures in the chips including pumps, valves, and channels allow the chips to accept different types of fluids to be entered the channel and along with flowing through the channels, exert their effects in the framework of different reactions. The chips are generally crystal, silicon, or elastomer in texture. These highly organized structures are equipped with discharging channels through which products as well as wastes of the reactions are secreted out. A particular advantage regarding the use of fluids in micro-scales over macro-scales lies in the fact that these fluids are much better processed in the chips when they applied as micro-scales. When the laboratory is miniaturized as a microchip and solutions are injected on a micro-scale, this combination makes a specialized construction referred to as "lab-on-chip". Taken together, micro-fluids are among the novel technologies which further than declining the costs; enhancing the test repeatability, sensitivity, accuracy, and speed; are emerged as widespread technology in laboratory diagnosis. They can be utilized for monitoring a wide spectrum of biological disorders including different types of cancers. When these microchips are used for cancer monitoring, circulatory tumor cells play a fundamental role.

Fabrication of BCP/Silica Scaffolds with Dual-Pore by Combining Fused Deposition Modeling and the Particle Leaching Method (압출 적층 조형법과 입자 추출법을 결합한 이중 공극 BCP/Silica 인공지지체의 제작)

  • Sa, Min-Woo;Kim, Jong Young
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.10
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    • pp.865-871
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    • 2016
  • In recent years, traditional scaffold fabrication techniques such as gas foaming, salt leaching, sponge replica, and freeze casting in tissue engineering have significantly limited sufficient mechanical property and cell interaction effect due to only random pores. Fused deposition modeling is the most apposite technology for fabricating the 3D scaffolds using the polymeric materials in tissue engineering application. In this study, 3D slurry mould was fabricated with a blended biphasic calcium phosphate (BCP)/Silica/Alginic acid sodium salt slurry in PCL mould and heated for two hours at $100^{\circ}C$ to harden the blended slurry. 3D dual-pore BCP/Silica scaffold, composed of macro pores interconnected with micro pores, was successfully fabricated by sintering at furnace of $1100^{\circ}C$. Surface morphology and 3D shape of dual-pore BCP/Silica scaffold from scanning electron microscopy were observed. Also, the mechanical properties of 3D BCP/Silica scaffold, according to blending ratio of alginic acid sodium salt, were evaluated through compression test.

Reduced Feedback Beamforming with a Large Antenna Array in Wireless Backhaul Downlink Systems (거대 배열 안테나 무선 백홀 하향 링크 시스템에서 피드백 량을 줄이기 위한 빔 형성 방법)

  • Park, Jaebum;Kwon, Girim;Park, Hyuncheol
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.12
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    • pp.1903-1913
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    • 2016
  • In this paper, we propose 2-stage beamformer with linear receiver in wireless backhaul downlink system where macro base station has large antenna array with sub-array structure. Also, to compare the system capacity, we apply 3-stage beamformer with zero-forcing precoder and calculate the achievable sum rate of received small cell base stations. Considering scattering and path-loss property of wireless backhaul channel, we combine precoding technique for spatial multiplexing and beamforming technique to overcome path-loss. Therefore, we design DFT-based fixed beam patterns for the first stage. The simulation results show that considering spatial multiplexing, proposed 2-stage beamformer with linear receiver can increase the achievable sum rate as well as reduce the feedback information.

Adventitious Root Cultures of Panax ginseng C.V. Meyer and Ginsenoside Production through Large-Scale Bioreactor System

  • Hahn, Eun-Joo;Kim, Yun-Soo;Yu, Kee-Won;Jeong, Cheol-Seung;Paek, Kee-Yoeup
    • Journal of Plant Biotechnology
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    • v.5 no.1
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    • pp.1-6
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    • 2003
  • The adventitious root of Panax ginseng C.A. Meyer is regarded as an efficient alternative to cell culture or hairy root culture for biomass production due to its fast growth and stable metabolite production. To determine optimal culture conditions for the bioreactor culture of ginseng roots, experiments have been conducted on physical and chemical factors such as bioreactor type, dissolved oxygen, gas supply, aeration, medium type, macro- and micro-elements, medium supplement during culture period, sucrose concentration, osmotic agents, medium pH and light. Elicitation is a key step to increase ginsenoside accumulation in the adventitious roots but biomass growth is severely inhibited by elicitor treatment. To obtain high ginsenoside content with avoiding biomass decrease, we applied two-stage bioreactor culture system. Ginseng adventitious roots were cultured for 40 days to maximize biomass increase followed by elicitation for 7 days to enhance ginsenoside accumulation. We also experimented on types and concentrations of jasmonate to determine optimal elicitation methods. In this paper, we discussed several factors affecting the root propagation and ginsenoside accumulation. Based on the results obtained from previous experiments we have established large-scale bioreactor system (1 ton-10 ton) for the efficient production of ginseng adventitious roots and bioactive compounds including ginsenoside. Still, experiments are on going in our laboratory to determine other bioactive compounds having effects on diet, high blood pressure, DPPH elimination and increasing memories.

Preliminary assessment of correlation between T-lymphocyte responses and control of porcine reproductive and respiratory syndrome virus (PRRSV) in piglets born after in-utero infection of a type 2 PRRSV

  • Cha, Sang-Ho;Bandaranayaka-Mudiyanselage, Carey;Bandaranayaka-Mudiyanselage, Chandima B.;Ajiththos, Dharani;Yoon, Kyoung-Jin;Gibson, Kathleen A.;Yu, Ji-Eun;Cho, In-Soo;Lee, Stephen S.;Chung, Chungwon J.
    • Korean Journal of Veterinary Research
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    • v.58 no.1
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    • pp.9-16
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    • 2018
  • A preliminary study into the protective mechanisms of adaptive immunity against porcine reproductive and respiratory syndrome virus (PRRSV) in piglets (n = 9) born to a gilt challenged intranasally with a type-2 PRRSV. Immune parameters (neutralizing antibodies, $CD3^+CD4^+$, $CD3^+CD8^+$, $CD3^+CD4^+CD8^+$ T-lymphocytes, and PRRSV-specific interferon $(IFN)-{\gamma}$ secreting T-lymphocytes) were compared with infection parameters (macro- and microscopic lung lesion, and PRRSV-infected porcine alveolar macrophages ($CD172{\alpha}^+PRRSV-N^+\;PAM$) as well as with plasma and lymphoid tissue viral loads. Percentages of three T-lymphocyte phenotypes in 14-days post-birth (dpb) peripheral blood mononuclear cell (PBMC) had significant negative correlations with percentages of $CD172{\alpha}^+PRRSV-N^+\;PAM$ (p < 0.05) as well as with macroscopic lung lesion (p < 0.01). Plasma and tissue viral loads had significant (p < 0.05) negative correlations with $CD3^+CD4^+CD8^+$ T-lymphocyte percentage in PBMC. Frequencies of $CD3^+CD8^+$ and $CD3^+CD4^+$ T-lymphocytes in 14-dpb PBMC had significant negative correlations with of lymph node (p = 0.04) and lung (p = 0.002) viral loads. $IFN-{\gamma}$-secreting T-lymphocytes frequency had a significant negative correlation with gross lung lesion severity (p = 0.002). However, neutralizing antibody titers had no significant negative correlation (p > 0.1) with infection parameters. The results indicate that T-lymphocytes contribute to controlling PRRSV replication in young piglets born after in-utero infection.

Cross-Layer Optimized Resource Allocation Scheme for OFDMA based Micro Base Stations (OFDMA 기반 마이크로 기지국을 위한 계층간 최적화된 자원할당 기법)

  • Cho, Sung-Hyun
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.6
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    • pp.49-56
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    • 2010
  • In this paper, a joint PHY-MAC layer optimized resource allocation scheme for OFDMA based micro base stations is investigated. We propose cross-layer optimized two-stage resource allocation scheme including cross-layer functional description and control information flow between PHY-MAC layers. The proposed two-stage resource allocation scheme consists of a user grouping stage and a resource allocation stage. In the user grouping stage, users are divided into a macro base station user group and a micro base station user group based on the PHY-MAC layer characteristics of each user. In the resource allocation stage, a scheduling scheme and an allotment of resources are determined. In the proposed scheme, diversity and adaptive modulation and coding (AMC) schemes are exploited as schedulers. Simulation results demonstrate that the proposed scheme increases the average cell throughput about 40~80 % compared to the conventional system without micro base stations.

Design and Implementation of Multimedia Education System on Mobile Device (모바일 단말에서의 SMIL을 이용한 멀티미디어 교육 시스템 설계 및 구현)

  • Lim Young-Jin;Seo Jung-Hee;Park Hung-Bog
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.581-584
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    • 2006
  • Cellular phones have been popularized and some of them even have access to the Internet. But the utilization of mobile phones has not been for education but only focused on particular services due to the text-based low capacity. This thesis proposes a multimedia education system using cell phones with SMIL. We can decrease the size of the parser and refute the resources of CPU by designing SMIL tag only, which is needed for multimedia education. In addition, the macro method for producing information for lectures will make possible decreased transmission quantity of multimedia contents and increased transmission efficiency. This will lead to overcoming the matter of insufficient CPU and memory, which is common to most mobile phone terminals.

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Mineral Uptake and Soluble Carbohydrates of Tomato Plants as Affected by Air Temperatures and Mineral Treatment Levels

  • Sung, Jwakyung;Yun, Hejin;Cho, Minji;Lee, Yejin;Chun, Hyenchung;Ha, Sangkeun;Sonn, Yeonkyu
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.4
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    • pp.305-311
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    • 2015
  • Both low and high temperatures affect plant growth and development at whole plant level, tissue and even cell level through a variety of metabolic changes. Temperature stress is one of frequently occurring problems in greenhouse crops in summer and winter seasons due to the wide-spread year-round cultivation. In the present study, we investigated the extent of the inhibition of growth, macro-element uptake and soluble carbohydrate production, and the effect of extra-supply of minerals as a means of the recovery from temperature damage. Tomato plants were grown five different growth temperatures (15/8, 20/13, 28/21, 33/23 and $36/26^{\circ}C$), and extra-supply of minerals was composed of 1.5- and 2.0-fold stronger than the standard nutrition (1/2 strength of Hoagland's solution). Temperature stress significantly adversely affected tomato growth and mineral uptake, whereas soluble carbohydrate accumulation represented temperature-dependent response, more accumulation at low temperature and more consumption at high temperature. The soluble sugars in leaves and stems were mostly declined with the supply of extra-minerals at low and optimal temperatures, whereas remained unchanged at high temperature. The starch levels also remained unchanged or slightly decreased.

Gerneral concept of dietary fiber and it's functionality (식품 중 식이섬유(Dietary fiber)의 의미와 기능성 고찰 -식이섬유의 특성과 기능을 중심으로-)

  • Shin, Dong-Hwa
    • Food Science and Industry
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    • v.52 no.1
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    • pp.84-99
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    • 2019
  • Dietary fiber is defined as soluble and insoluble polysaccharide consisted in the plant cell wall-associated fibers naturally occurring in fruits, vegetables, and cereal products, and of isolated fibers that are added to processed foods which are also artificially modified. There are so many difference types of dietary fibers as arabinoxylan, polydextrose chicory, oligosccharide. inulin, pectin, bran, cellulose, ${\beta}$-glucan, resistant starch and some seaweed polymers as alginate. Most of them provide many biological benefits in the intestine, as lower risk for developing coronary heart disease, stroke, hypertension, diabetes, obesity and some of the gastrointestinal disease like as colon cancer. And also lowering cholesterol levels, improves glycemic and insulin sensitivity to non-diabetic and diabetic persons including immune system. Beside of many benefits, average consumers in developed and under developing countries take far less amounts of dietary fiber that international organization recommended. Adequate intake of dietary fiber is 14g/1,000kcal base using the energy guide line of 2,000kcal/day for women and 26,000 kcal/day for men, dietary intake is 28g/day of adult women and 36g/day for adult men. The mechanisms behind the reported effects of dietary fiber on metabolic health are not fully well established. It is suggested that changes in intestinal viscosity resulting mucus increasing, macro-nutrients absorption, rate of passage of large intestinal, production of short chain fatty acids by fermentation. Production of gut hormones and changes of microbiota in intestine. It is necessary to do more research in this field in the future and combined interdisciplinary works together.