• 제목/요약/키워드: m-Healthcare

검색결과 574건 처리시간 0.027초

The Level of UVB-induced DNA Damage and Chemoprevention Effect of Paeoniflorin in Normal Human Epidermal Kerationcytes

  • Lim, Jun-Man;Park, Mun-Eok;Lee, Sang-Hwa;Kang, Sang-Jin;Cho, Wan-Goo;Rang, Moon-Jeong
    • Molecular & Cellular Toxicology
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    • 제1권2호
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    • pp.111-115
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    • 2005
  • Ultraviolet (UV) radiation to mammalian skin is known to alter cellular function via generation of Reactive Oxygen Species (ROS), DNA damage and DNA lesions, such as pyrimidine dimmers and photoproducts, which could lead to DNA mutation if they are not repaired. In this study, we have investigated the reduction of DNA damage and of apoptosis with a particular attention to genetic effect of paeoniflorin in Normal Human Epidermal Keratinocytes (NHEK). After UVB irradiation from $10\;to\;500mJ/cm^{2}$ to NHEK, Mean Tail Moments (MTM) were increased with UVB dose increase. The greatest amount of strand breaks was induced at $500mJ/cm^{2}$ of UVB. Even at the lowest dose of UVB ($10mJ/cm^{2}$), change in MTM was detected (P<0.0001). Pretreated cell with 0.1% paeoniflorin maximally reduced the level of DNA damage to about 21.3%, compared to untreated cell. In the lower concentrations less than 0.01% of paeoniflorin, MTM had a small increase but paeoniflorin still had reductive effects of DNA damage. We measured the apoptosis suppression of paeoniflorin with annexin V flous staining kit. As we observed under the fluorescence microscopy to detect apoptosis in the irradiated cell, the fluorescence intensity was clearly increased in the untreated cell, but decreased in treated cells with paeoniflorin. These results suggest that paeoniflorin reduces the alteration of cell membranes and prevents DNA damage. Therefore, the use of paeoniflorin as a free radical scavenger to reduce the harmful effects of UV lights such as chronic skin damage, wrinkling and skin cancer can be useful to prevent the formation of photooxidants that result in radical damage.

U-Healthcare 표준화 기술 동향에 관한 연구 (A Study of U-Healthcare Standardization Technology Trends)

  • 허윤아;이근호
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2014년도 추계학술발표대회
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    • pp.787-789
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    • 2014
  • U-Health Care 서비스를 제공하려면 때와 장소를 가리지 않고 어디서든 건강상태를 진단 할 수 있는 생체측정기술이 필요하다. 그래서 현재는 정보통신기술을 이용하여 당뇨병, 고혈압 등 만성질환을 앓고 있는 환자들을 대상으로 환자들의 생활공간과 진료가 결합된 서비스가 U-Healthcare서비스이다. 본 논문은 최근 U-Healthcare 분야에서 가장 최근의 표준흐름을 분석한다. U-Healthcare에서 호환성과 신뢰성의 문제가 생기지 않도록 하기위해 표준화가 가장 활발하게 진행 중인 국제 표준화 동향과 IEEE 11073 PHD, HL7 CDA 등의 국제 표준화 동향에 대해 살피면서 국제 표준기반 U-Healthcare 플랫폼에 대해 알아본다.

U-Healthcare 서비스의 개인정보보호를 위한 보안 요구사항에 관한 연구 (A Study on The Security Requirements for Privacy of U-Healthcare Service)

  • 채하나;송양의
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2012년도 추계학술발표대회
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    • pp.1092-1095
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    • 2012
  • IT융합기술인 U-Healthcare 서비스는 건강관리, 질병 예방, 사후관리 등 필요한 의료 서비스를 의료기관외의 장소에서 언제 어디서나 서비스를 제공받을 수 있다는 점에서 각광을 받고 있다. U-Healthcare 서비스에서 다루는 대다수의 정보는 개인정보 중에서도 민감한 개인의 건강정보를 포함하고 있어 개인정보보호에 대한 사회적 요구가 높아지는 시점에서 유출에 대한 피해 우려는 더 커지고 있다. 본 논문에서는 U-Healthcare 서비스에서 개인정보를 보호받을 수 있는 보안 요구사항을 도출해낸다. 이 연구를 통해 U-Healthcare 서비스의 보안 수준을 향상 시키고 일반 개인정보보다 피해가 큰 개인건강정보의 유출을 예방한다.

Influences and Barriers in the Kingdom of Saudi Arabia Affecting Technology Adoption in Healthcare: A Review Paper

  • Abdulaziz Alomari;Ben Soh
    • International Journal of Computer Science & Network Security
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    • 제23권6호
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    • pp.59-67
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    • 2023
  • The healthcare industry continues to adopt and integrate smart technology in its operations, from medical devices to managing operations. However, the adoption curve has not been smooth, and the historical record of technology adoption in the Kingdom of Saudi Arabia reveals the existence of both known and unknown issues. This review paper is aimed to explain the influences and barriers present in the Saudi healthcare sector affecting IoT technology adoption. A comprehensive discussion of the literature illustrated that Vision 2030, the privatisation trend, transformation in disease patterns and ageing, issues in management and increasing public awareness are the key drivers that may influence the need for the medical Internet of Things (mIoT) in Saudi healthcare. However, based on the past trend, the introduction and adoption of mIoT will likely experience issues such as noncompliance from doctors and nurses due to negative beliefs, lack of knowledge and inadequate perception of effort requirements. Thus, in-depth research of the factors associated with mIoT technology adoption is suggested for a smooth transition.