• 대한약침학회지
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• 제10권1호통권22호
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• pp.23-36
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• 2007

Objective : We performed this study in order to investigate the effects of Paljeongsan-gamibang(八正散加味方) on the renal failure. Methods : We injected 8ml/kg of 50% glycerol on the rats. And then administered Paljeongsan-gamibang extract ; 209mg/200g/day to sample group during 3 days and observed the body temperature, urine volume, stool volume and the levels of creatinine, glucose, inorganic phosphorus, Na+, K+, Cl-, threonine, tyrosine in blood and creatinine, glucose, threonine, tyrosine in urine. Results : 1, The sample group administered Paljeongsan-gamibang showed a suppressive effect of body temperature, an improving effect in capability of concentrating urine at convoluted tubule and showed an increasing effect of stool volume. 2. The sample group administered Paljeongsan-gamibang showed a lowering effect in creatinine level in blood and showed an increasing effect in the levels of inorganic phosphorus, Na+, K+, Cl-, threonine and tyrosine in blood. 3. The sample group administered Paljeongsan-gamibang showed an increasing effect in creatinine level in urine and showed a lowering effect in the levels of glucose, inorganic phosphorus, threonine and tyrosine in urine. Conclusions : Conclusively, Paljeongsan-gamibang was recognized to have a curative effect against the damage of rat kidney induced by 50% glycerol, especially to improve the capability of reabsorption in proximal convoluted tubule.

• 산경연구논집
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• 제8권7호
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• pp.63-70
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• 2017

Purpose - Due to the lack of physical activities and the increase of sedentary behaviors such as screen time, the health condition for contemporaries has been deteriorating. This study is designed to investigate how the use of worktable or tools unfit for body and sedentary behaviors can exercise influence on muscular skeletal disease and how it has an impact on lowering work efficiency and the quality of life with the medium of the muscular skeletal disease. Research design, data, and methodology - The research has developed a questionnaire with 5 hypothesis. The questionnaires were also made by interview and E-mail. 350 copies of questionnaires were distributed and 315 questionnaire were used for the analysis as valid data responses. SPSS ver.22.0 were used and made Cronbach's and reliability test, correlation, Baron & α Kenny 3 step mediated regression analysis. Results - The research has found that living environment factors have positive effect on the occurrence of musculosketal disease. Particularly, repeated use of unfit worktable or tools has a positive effect on the muscular skeletal disorder. And sedentary lifestyle also has a positive effect on the disease. The musculoskeletal disease caused by living environment has a positive impact on lowering the work efficiency. This study has also showed that the muscular skeletal disease has mediated the relationship between the living environment factors and the decrease of work efficiency due to musculoskeletal disease. The musculoskeletal disorders can effect the decrease of the quality of life as well, for the decrease of work efficiency has a positive effect on lowering the quality of life. Conclusions - Sedentary lifestyles, the use of worktable unfit for body, and the repeated use of a tool have caused the increase of muscular-skeletal diseases, and reduction of productivity as well as the hight cost of medical treatment for our contemporaries. Understanding the cause of disease morbidity, finding ways to prevent the disease, and educating people about them would contribute not only to improvement of individual health but also to the advancement of welfare for all.

• Journal of Nutrition and Health
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• 제23권7호
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• pp.477-491
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• 1990

To observe the effect of dietary n6 linoleic acid, n6 gamma-linolenic acid and n3 alphalinolenic acid aon plasma lipid composition and platelet aggregation, twenty college women were divided into 4 groups and treated for 2 weeks with experimental diets supplying fat at 23% cal which were different only in fatty acid composition. Dietary fat was corn oil(CO) as a source of n6 linoleic acid(LA), perilla oil(PO) for n3 alpha-linolenic acid(ALA) and evenign primrose oil(EPO) for n6 gamma-linolenic acid(GLA). Plasma cholesterol level was slightly decreased by PL(13.5g) but significantly increased by equal amount of CO. However, there was similar hypocholeaterolemic effect when double amount of CO(27.0g), was supplemented. Therefore, total fat unsaturation may be more important factor for plasma cholesterol-lowering effect than the structure of fatty acid itself. Plasma cholesterol level was not lowered by supplement of GLA in CO diet. There was similar trend in hypotriglyceridemic effect by PO and CO as in plasma cholesterol. Plasma TG level was rather increased but not significantly by GLA supplement to CO diet. Overall, plasma lipid-lowering effect was greater by ALA than LA and GLA effect was not greater than by LA. GLA supplement did not significantly improve lipid compositions to prevent against CHD. There was no significant change both in fatty acid composition in platelet and ADP-induced platelet aggregation by GLA supplement to corn oil diet and by ALA in PO diet in young women.

• 한국지역사회생활과학회지
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• 제16권3호
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• pp.127-132
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• 2005

The aim of this study is to investigate the effects of hot water soluble extract from Angelicae Radix on the components of serum and liver and the effects on the antioxidant system. For this purpose, five experimental groups were set up. And for fat source, perila oil enough with unsaturated fatty acid and beef tallow enough with saturated fatty acid were supplemented to the rats together with hot water soluble extract from Angelicae Radixs. Five experimental groups kept eight Sprague-Dawley rats respectively. They were CO group supplemented with basic diet of AIN-93, PO group supplemented with perila oil, POA group supplemented with perila oil and hot water soluble extract from Angelicae Radix, BT group supplemented with beef tallow, and BTA group supplemented with beef tallow and hot water soluble extract from Angelicae Radix. The results were; 1) Final weight, weight gain, fluid intake and FER were not different significantly among the experimental groups, 2) Significant difference of food intake was observed(p<0.05) in BTA group only, 3) No significant difference was observed in serum total lipid, serum triglyceride and HDL cholesterol among experimental groups. Serum total cholesterol and LDL cholesterol were significantly low(p<0.05) in the group supplemented with beef tallow which was with hot water soluble extract from Angelicae Radix (BTA group). 4)Liver total cholesterol in liver was low in groups supplemented with perila oil and hot water soluble extract from Angelicae Radix. In summary, hot water soluble extract from Angelicae Radix did not affect the weight gain, fluid intake and food efficiency ratio among the experimental groups, but had an effect of lowering food intake, serum total cholesterol and serum LDL cholesterol significantly in the groups which were supplemented with beef tallow and hot water soluble extract from Angelicae Radix. The effect of lowering liver total cholesterol with the supplementation of hot water soluble extract from AnRelicae Radix was observed in perila oil group only. The effect of lowering cholesterol with the supplementation of hot water soluble extract from Angelicae Radix was observed both in serum and in liver.

• Nutrition Research and Practice
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• 제10권4호
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• pp.418-423
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• 2016

BACKGROUND/OBJECTIVES: Spirulina, a blue-green alga, is widely produced and commercialized as a dietary supplement with bio- and immune-modulatory functions. We have previously shown that spirulina had favorable effects on lipid profiles, immune functions, and antioxidant capacity in healthy Korean elderly. Despite favorable effect of spirulina supplementation, some sub-populations have shown a poor response to supplementation. Obesity is a factor related to poor-response. Therefore, the purpose of this study was to determine the immuno-modulation, antioxidant capacity, and lipid-lowering effect of spirulina in obese and non-obese Korean elderly. SUBJECTS/METHODS: The subjects were 78 elderly aged 60-87 years. In a randomized double blind, placebo-controlled study, subjects were fed either placebo or spirulina daily, at 8 g for 12 weeks. Subjects were divided into the non-obese group and the obese group based on body mass index (BMI) criteria for Asians suggested by the International Obesity Task Force: $BMI<25kg/m^2$ (non-obese) and $BMI{\geq}25kg/m^2$ (obese). RESULTS: In the non-obese group, spirulina supplementation showed a significant lowering effect on plasma concentration of total cholesterol and LDL-cholesterol, a significant increase in interleukin (IL)-2 concentration (P < 0.01) and a significant increment (P < 0.05) in IL-2/IL-6 ratio, and a significant increase in total antioxidant status level and a significant decrease in thiobarbituric acid reactive substances level. However, these effects were not observed in the obese group. CONCLUSION: These results demonstrated that blood lipid lowering and immune and antioxidant improving response for spirulina supplement was affected by obesity in Korean elderly.

• Journal of Nutrition and Health
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• 제36권5호
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• pp.425-436
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• 2003

The present study was conducted to evaluate the usefulness of common Korean legumes as a high-fiber supplement in therapeutic diets for diabetic patients. Streptozotocin-induced diabetic rats were used as animal models and four kinds of legumes, black soybean (BS), yellow soybean (YS), green pea (GP) and soybean curd residue (SCR) were tested as high-fiber supplements. Seven groups of normal and streptozotocin-induced diabetic rats were fed isocaloric experimental diets containing 8％ dietary fiber from one of four legumes or purified cellulose and pectin for 6 weeks. The effects of the legumes on the glucose and lipid metabolism of diabetic rats was examined and compared with the effects of cellulose and pectin. The legume supplementation did not show any beneficial effect on glucose tolerance, however, it exhibited a plasma cholesterol-lowering effect in diabetic rats. The cholesterol-lowering action was especially strong in BS and the degree of the effect was comparable to that of pectin. The levels of total lipids, cholesterol, and triglyceride in the hepatic tissues of rats fed legume diets were similar to those of the pectin group. All legume supplements induced an increase in fecal steroid excretion. The fecal cholesterol contents were significantly high following the supplementations of YS and SCR (p < 0.05). The excretion of fecal bile acids in the BS and YS groups was significantly higher than it was in the pectin group (p < 0.05). Concentration of lipid peroxidation products in the blood and urine of diabetic animals was lower in the legume groups than in the cellulose group. The levels of hepatic lipid peroxidation products were significantly lower in the BS and YS groups than in the pectin group (p < 0.05). From the results of this study, the plasma cholesterol-lowering effect of BS is possibly due to the significant (p < 0.05) in-crease in fecal steroid excretion, which suggests that BS could be beneficial in improving abnormal lipid metabolism in diabetic rats. (Korean J Nutrition 36(5): 425∼436, 2003)

• 한국지역사회생활과학회지
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• 제15권1호
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• pp.77-83
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• 2004

The aim of this study was to investigate the effects of L-carnitine on the components of serum and liver and the effects on the anti-oxidant system. For this purpose, five experimental groups were setup. For fat source, perilla oil enough with unsaturated fatty acid and beeftallow enough with saturated fatty acid were supplemented together with L-carnitine to the rats. Five experimental groups kept eight Sprague-Dawley rats respectively, They were co group supplemented with basic diet or AIN-93, PO group supplemented with perilla oil, POC group supplemented with perilla oil and L-carnitine, BT group supplemented with beeftallow, and BTC group supplemented with beeftallow and L- carnitine. The results are. 1) Weight gain, food intake and FER were not different significantly among the experimental groups. 2) Significant difference was observed in serum total lipid(P<0.05), serum triglyceride(P<0.05), serum total cholesterol (P<0.05)and serum LDL cholesterol(P<0.05). Serum total lipid and serum triglyceride were significantly low in the groups supplemented with L-carnitine. Serum total cholesterol showed difference with the supplementation of L-carnitine in BTC only. LDL cholesterol showed no significant difference with the supplementation of L-carnatine, but total values of LDL-cholesterol were high in groups supplemented with beeftallow. 3) Total cholesterol in liver was low in POC group with the supplementation of L-carnitine however, there was no difference in BTC group with the supplementation of L-carnitine. In summary, dietary L-carnitine did not influence the weight gain, food intake and food efficiency ratio among the experimental groups, but had an effect of lowering the serum total lipid and triglyceride significantly in both groups which were supplemented with L-carnitine. The effect of lowering of sew total cholesterol with the supplementation of L-carnitine in beeftallow group(BTC) only. The effect of lowering of liver total cholesterol with the supplementation of L-carnitine in perilla oil group(POC) only.

• 한국건설관리학회논문집
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• 제10권3호
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• pp.72-82
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• 2009

건설서비스 양허하한선 인하 문제는 국내 중 소 건설업체의 이해관계와 밀접하게 연관되어 있는 바, 국내 관련 제도 및 건설시장에 미치는 영향에 대한 세부적 분석이 필요하다. 특히 중 소 건설업체를 위한 '지역제한입찰제도' 및 '지역의무공동도급제도' 등에 영향을 미치고, 궁극적으로는 이들 업체의 수주시장에도 변화가 예상되므로 이에 대한 사전적 검토가 필수적이다. 그러나 이러한 양허하한선을 낮출 경우 우리나라의 건설산업에 어떤 영향을 미치는지에 대한 연구는 없는 실정이다. 따라서 본 연구에서는 건설서비스 양허하한선 조정으로 인한 실제 수주시장의 변화를 전망해 보고 그 실질적인 효과를 분석하여 '건설서비스 양허하한선 인하' 문제에 대한 기본 입장 정립의 근거 자료를 제시하고자 한다. 현재 WTO GPA의 적용을 받는 우리나라의 양허하한선은 정부발주공사의 경우는 500만 SDR(74억원)이며, 지자체와 기타공사의 경우에는 1,500만 SDR(222억원)이다. 정부는 지방자치단체 및 공기업 등 기타기관의 건설서비스 양허하한선에 대하여 '지역의무공동도급제도' 등을 고려하여 높은 수준을 유지하는 것이다. 우리나라의 지방정부기관 및 공기업의 건설서비스의 양허하한선은 일본과 함께 현재 1,500만 SDR로서, 여타국의 500만 SDR에 비해 월등히 높게 설정된 상황이며 최근 미국을 중심으로 EC 등 주요 회원국은 지방정부기관 및 공기업의 하한선을 외국의 경우와 같이 500만 SDR로 인하할 것을 요구하고 있다. 분석결과 이러한 500만 SDR로의 개방 확대는 '07년 기준으로 총 2조 105억원 규모의 시장이 축소되어, 이는 지역업체들에게 부담을 줄 것으로 예상된다. 지역업체들의 수주 비중은 규모가 작은 공사일수록 높아지므로, 총 2조 105억원 규모의 시장감소(공동도급 1조 6,802억원, 단독도급 3,407억원)는 지역업체 수주활동에 적지 않은 영향을 미칠 것으로 분석된다.

• 아시안잔디학회지
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• 제17권4호
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• pp.165-172
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• 2003

본 연구는 녹지의 배치와 식재형태가 기온저감효과에 미치는 영향을 파악한 결과 다음과 같은 점이 밝혀졌다. 1) 녹지의 기온분포도로부터 고온역은 주변시 가지에서, 저온역은 각 녹지내의 식재지주변과 소하천주변에서 확인되었다. 2) 녹지의 배치와 기온과의 관계를 보면, 저온역은 각 녹지와 거의 일치하고 녹지간 시가지 및 풍하쪽에도 저온역이 형성되었다. 3) 녹지간 시가지와 기온과의 관계를 보면 저온역은 풍하쪽 시가지뿐 아니라 녹지간 시가지에서도 나타났다. 또한, 풍상쪽에 녹지가 존재하지 않은 경우에도 녹지간 시가지는 주변 시가지 보다 낮은 기온이었다. 4) 토지피복비율과 기온에서 식재지, 초지 및 수면이 증가하면 모두 기온저감에 효과적이고, 나지의 증가는 기온상승에 효과적이다. 5) 교목, 소교목의 순으로 그 그루의 증가는 기온저감에 유효하게 관련되어 있는 것이 파악되었다.

• 한국정보통신학회논문지
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• 제19권11호
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• pp.2643-2648
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• 2015

본 연구에서는 비대칭 이중게이트 MOSFET의 채널 내 도핑농도분포에 대한 드레인유도장벽감소(Drain Induced Barrier Lowering; DIBL)에 대하여 분석하고자한다. DIBL은 드레인 전압에 의하여 소스 측 전위장벽이 낮아지는 효과로서 중요한 단채널 효과이다. 이를 분석하기 위하여 포아송방정식을 이용하여 해석학적 전위분포를 구하였으며 전위분포에 영향을 미치는 채널도핑농도의 분포함수변화에 대하여 DIBL을 관찰하였다. 채널길이, 채널두께, 상하단 게이트 산화막 두께, 하단 게이트 전압 등을 파라미터로 하여 DIBL을 관찰하였다. 결과적으로 DIBL은 채널도핑 농도분포함수의 변수인 이온주입범위 및 분포편차에 변화를 나타냈다. 특히 두 변수에 대한 DIBL의 변화는 최대채널도핑농도가 $10^{18}/cm^3$ 정도로 고도핑 되었을 경우 더욱 현저히 나타나고 있었다. 채널길이가 감소할수록 그리고 채널두께가 증가할수록 DIBL은 증가하였으며 하단 게이트 전압과 상하단게이트 산화막 두께가 증가할수록 DIBL은 증가하였다.