• 제목/요약/키워드: low-fertility

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한국의료패널을 이용한 구급 이송 서비스 이용 특성 분석: 임신, 출산, 산후기 여성을 중심으로 (Analysis of the Use of Ambulance Services Among Pregnant, Childbearing, and Postpartum Women Using Data from the Korea Health Panel)

  • 강경희
    • 한국화재소방학회논문지
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    • 제33권6호
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    • pp.152-158
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    • 2019
  • 본 연구에서는 한국보건사회연구원과 국민건강보험공단의 한국의료패널 2008-2016년 연간 데이터(Version 1.5)를 이용해 임신, 출산, 산후기 여성의 구급 이송 서비스 이용 특성을 분석하였다. 분석 결과를 요약하면, 첫째, 임신, 출산 및 산후기 여성의 119 구급차, 민간 구급차 등 구급 이송 서비스 이용률은 12.0%로 전체 구급 이송 서비스 이용률 18.9%보다 상대적으로 낮았다. 둘째, 임신, 출산 및 산후기 여성의 응급에서 분만이 38.7%로 가장 큰 비중을 차지하였으며, 진통 및 분만의 합병증이 20.0%, 유산된 임신이 17.3% 등의 순으로 나타났다. 셋째, 임신, 출산 및 산후기 여성의 구급 이송 서비스 이용 특성 중 연 평균 가구소득, 응급실 도착 소요시간, 응급실 도착 지연 인식 등에서 구급 이송 서비스의 이용자 집단과 비이용자 집단 사이에 통계적으로 유의한 차이가 나타났다. 따라서 저출산과 고령 산모로 인하여 분만 취약지가 늘어날수록 임신, 출산, 산후기 여성을 위한 사회안전망으로서 구급 이송 서비스의 양적 확대와 질적 제고는 더욱 시급한 과제가 될 것이다.

Impact of sperm DNA fragmentation on clinical in vitro fertilization outcomes

  • Choi, Hwa Young;Kim, Seul Ki;Kim, Seok Hyun;Choi, Young Min;Jee, Byung Chul
    • Clinical and Experimental Reproductive Medicine
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    • 제44권4호
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    • pp.224-231
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    • 2017
  • Objective: We studied the association between sperm DNA fragmentation (SDF) and several clinical in vitro fertilization outcomes. Methods: We retrospectively analyzed 169 consecutive fresh IVF cycles. Semen was collected on the day of oocyte retrieval, and we assessed standard semen parameters and the SDF level (by terminal deoxynucleotidyl transferase dUTP nick-end labeling). Poor ovarian response (POR) was defined as the collection of three or fewer mature oocytes. Oocytes were inseminated by the conventional method or intracytoplasmic sperm injection. Results: SDF did not affect the fertilization or pregnancy rate, but did have a significant effect on the miscarriage rate. In the miscarriage group (n = 10), the SDF level was significantly higher (23.9% vs. 14.1%) and number of mature oocytes was significantly lower (4.3 vs. 7.6) than in the live birth group (n = 45). Multiple regression analysis showed that SDF was an independent predictor of miscarriage (odds ratio, 1.051; 95% confidence interval, 1.001-1.104). The cutoffs for the SDF level and number of mature oocytes that could predict miscarriage were > 13% and ${\leq}3$, respectively. In the low-SDF group (${\leq}13%$), the miscarriage rate was similar in POR patients and those with a normal ovarian response (NOR; 14.2% vs. 4.3%). In the high-SDF group ( > 13%), the miscarriage rate was significantly higher in the POR group than in the NOR group (60.0% vs. 13.3%, p= 0.045). Conclusion: Our study demonstrated that a high SDF level ( > 13%) was associated with a high miscarriage rate, and that it mainly contributed to miscarriage in the POR group. The results suggest that SDF measurements should be considered in couples with POR in order to predict the prognosis of the pregnancy.

우울증과 생활사건 스트레스에 대한 폐경전${\cdot}$후 비교 (A Comparative Study of Depression and Stress Related Life Events among Women in the Menopausal Stage)

  • 정은순
    • 대한간호학회지
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    • 제30권4호
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    • pp.956-966
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    • 2000
  • The purpose of this study was to examine the comparative between depression and stress related to life events among women in the menopausal stage. Menopausal stages were divided into two groups: Pre and post-menopausal stages. The degree of depression and stress related to life events between pre and post menopausal women were compared to each other. Women, aged between 41 and 59 years, answered self-reported questionnaires which included Zung's depression scale and life events scale modified by Lee (1984). Findings were as follows; 1) The mean score of premenopausal women who experienced depression was 39.66, and for post-menopausal women the score was 41.45. There was no significant differences in depression levels between pre and post menopausal group.s (t=-1.55, p=.122). 2) Menopausal women experienced low levels of stress related to life events. There were no significant differences between pre and post menopausal groups(t=.527, p>.05). Both pre and post menopausal groups were highly concerned about education issues of their children and disharmony between couples. 3) There was a significant relationship between depression and stress related to life events among post-menopausal groups (r=.22, p<.01). Based on the findings of this study, the menopausal depression was associated with stress related to life events, especially among post-menopausal women. Feelings of lost fertility and feminine attributies result in menopausal depression, which is significantly correlated with women's negative perception of their life events. Therefore, nursing intervention needs to develop to help reduce the levels of depression and overcome their negative perception of the menopausal experience. Nurses should develop nursing strategies to help menopausal women to have positive perceptions and enhance quality of life by assisting their adaptability to physiological and psychological changes related to menopause.

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A Study on BMPR-IB Genes of Bayanbulak Sheep

  • Zuo, Beiyao;Qian, Hongguang;Wang, Ziyu;Wang, Xu;Nisa, Noor;Bayier, Aierdin;Ying, Shijia;Hu, Xiaolong;Gong, Changhai;Guo, Zhiqin;Wang, Feng
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권1호
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    • pp.36-42
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    • 2013
  • The average twin lambing rate of Bayanbulak sheep is 2% to 3%. However, a flock of sheep with a close genetic relationship and an average of 2 to 3 lambs per birth has been found recently. To determine the major genes controlling the prolificacy of the flock in the present study, the flock was designated A while 100 normal Bayanbulak sheep were randomly selected to comprise the control flock B. Ligase detection reaction method was applied to detect and analyze the 10 mutational loci of the 3 candidate prolificacy genes including bone morphogenetic protein type I receptors, bone morphogenetic protein 15, and growth differentiation factor 9. The 10 mutational loci are as follows: FecB locus of the BMPR-IB gene; $FecX^I$, $FecX^B$, $FecX^L$, $FecX^H$, $FecX^G$, and $FecX^R$ of the BMP15 gene; and G1, G8, and FecTT of the GDF9 gene. Two mutations including BMPR-IB/FecB and GDF9/G1 were found in Bayanbulak sheep. Independence test results of the two flocks demonstrate that the FecB locus has a significant effect on the lambing number of Bayanbulak sheep. However, the mutation frequency of the G1 locus in GDF9 is very low. Independence test results demonstrate that the GDF9 locus does not have a significant impact on the lambing performance of Bayanbulak sheep. Among the 10 detected loci, BMPR-IB/FecB is the major gene that influences the high lambing rate of Bayanbulak sheep.

대두근류균(大豆根瘤菌)의 질소고정(窒素固定)에 관한 연구 -III. 신개간지(新開墾地) 토양에서 근류균(根瘤菌)의 접종(接種) 및 개량제시용이 질소고정(窒素固定)과 대두수량에 미치는 효과 (Studies on Symbiotic Nitrogen Fixation in Soybeans -III. Effects of Soil Improvement on N2 Fixation and Yield of Soybean Inoculated with Rhizobium japonicum in Newly Reclaimed Upland Soil)

  • 류진창;이상규;이혁호;홍종운;조무제
    • 한국토양비료학회지
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    • 제16권2호
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    • pp.188-194
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    • 1983
  • 토양비옥도가 극(極)히 낮은 신개간지(新開墾地)에 있어서 근류균(根瘤菌)의 접종(接種) 및 비료(肥料)와 개량제 시용(施用)이 질소고정(窒素固定)과 대두수량에 미치는 영향(影響)을 밝히고자 pot시험(試驗)을 수행하였던 바 그 결과(結果)를 요약(要約)하면 다음과 같다. 1. 대두(大豆) 근류(根瘤)에 의(依)한 질소고정량(窒素固定量)은 근류균(根瘤菌)의 접종(接種)과 비료(肥料) 및 개량제 시용(施用)으로 현저히 증가하였다. 2. 근류균(根瘤菌) 접종(接種)으로 질소흡수량 및 질소고정량(窒素固定量)을 높여 콩수량을 4~10% 증대시켰다. 3. 콩 다수확재배기술체계 확립(確立)을 위하여 토양비옥도가 극(極)히 낮은 신개간지(新開墾地)에서는 개량제의 시용(施用)과 근류균(根瘤菌)과 접종(接種)이 병행되어야 할 것으로 나타났다.

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Efficacy of Cyanobacterial Biofertilizer (CBB) on Leaf Yield and Quality of Mulberry and its Impact on Silkworm Cocoon Characters

  • Dasappa D.M. Ram Rao;Ramaswamy S.N.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제13권1호
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    • pp.15-22
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    • 2006
  • An experiment was conducted to study the efficiency of cyanobacterial biofertilizer (CBB) with chemical (NPK) fertilizer on quantitative and qualitative characters of mulberry variety Kanva-2. Their influences on silkworm growth and cocoon characters were also studied. Ten different CBB and NPK fertilizer treatments were given to 5000 plants of established mulberry garden. Treatments were of four types viz., (i) T1 to T7: single and combination dose of CBB+50% NPK (ii) T8: combination dose of CBB + 25%NPK, (iii) T9: CBB only and (iv) T10: control-l00% NPK. Soil pH decreased and nutrients status increased in CBB (T1- T9) treated plots. Average of ten crops data on quantitative traits revealed that T7 (CBB [N. muscorum (1.0 g), A. variahilis (1.0) and S. millei (1.0 g)] + 50% NPK) was very effective in improving growth parameters. Leaf yield was also found high in treatment T7 (32.12 tons/ha/yr.) followed by T10 (31.17 tons/ha/yr.) and T8 (27.67 tons/ha/yr.). Leaf quality characters were found high in T7 and low in T9. Most of the quality traits in T7 are on par with control no. The results revealed that reduction in the dose of chemical fertilizers in T7 did not affect the leaf yield and leaf quality traits of mulberry. This clearly indicates that the efficiency of CBB (T7) provides nitrogen, increases essential nutrients available in soil, maintain soil pH and supply growth substances required for the improvement of leaf yield and leaf quality of mulberry. Bioassay study also revealed no significant difference in silkworm growth and cocoon characters between treatments T7 and T10. Economics calculated revealed that T7 is highly economical and beneficial over T10 by gaining an amount of Rs. 660/-/acre/crop. Thus, treatment T7 containing N. muscorum (1.0 g), A. variahilis (1.0 g) and S. millei (1.0 g) + 50% NPK fertilizers can be recommended to sericulturists mainly to reduce the use of NPK fertilizers, by saving 50% of its cost and to improve soil fertility conditions, which in turn improves leaf yield and quality of mulberry.

일본 분양아파트의 생활서비스프로그램 운영실태 사례 연구 (A Case Study on the Operation and Management of Community Service Programs in Japanese Condominiums)

  • 강순주
    • 한국실내디자인학회논문집
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    • 제20권2호
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    • pp.85-93
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    • 2011
  • The Japanese housing market has implemented management and operation systems of community service ahead of the Korean market. This paper examines case studies of Japanese community services by reviewing related studies, studying homepages, and conducting in-depth interviews with management staff. The goal of this study is to find marketing strategies and the proper management practices in preparation for the upcoming low-fertility and aging society. The results of this study are as follows: 1) After Japan's bubble economy burst in 1985, so called that incorporated various community facilities with life services were introduced to the Japanese housing market in order to cope with the diversifying family types and lifestyles. This new trend was also due in part to customers' increasing demands for convenient urban condominiums. 2) In Japan, many developers and construction companies have run the management of community service programs and created new business models in collaboration with other affiliated companies. However, many of these programs have been found even more successful and reliable when the facility management companies collaborate with local service providers instead of relying solely on affiliated companies. 3) The early stage of life services began with "front-desk services", but these have evolved into more upgraded "concierge services" that can provide residents with tailored services and conveniences. Furthermore, some of the service providers have encouraged resident participation in the process of designing and implementing their community services. 4) In Korea, most construction companies and developers are still oriented toward providing hardware such as spaces and facilities in developing their community services. Therefore, companies with high market reputations must seek alternative ways to maintain and enhance their brand values by implementing new approaches in collaboration with both affiliated companies and local service providers. This can be done by finding new notions of managing and operating community services through research and development.

한국 30대 미혼여성의 결혼견해 영향요인: 2012 사회조사 기반 (Factors Affecting Opinions on Marriage of Unmarried Women in Their 30's in Korea: Based on 2012 Social Survey)

  • 이성희;권현수
    • 한국산학기술학회논문지
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    • 제16권1호
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    • pp.606-616
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    • 2015
  • 본 연구는 한국 30대 미혼여성의 결혼견해에 영향을 미치는 요인을 파악하기 위해 수행되었다. 2012년 사회조사 자료 중 30대 미혼여성 529명의 자료가 분석에 이용되었다. 자료는 SPSS Ver. 20.0을 이용하여 ${\chi}^2$ test와 위계적 로지스틱 회귀분석을 통해 분석되었다. 연구결과 대상자의 연령(Exp(b)=.90,p=.025), 이혼에 대한 견해(Exp(b)=3.81,p<.001), 재혼에 대한 견해(Exp(b)=3.09,p=.001) 그리고 결혼관(Exp(b)=.80,p<.001)이 결혼견해에 영향하는 요인으로 밝혀졌다. 또한 30에서 34세 미혼여성과 35에서 39세 미혼여성간의 결혼견해에 영향을 미치는 요인의 차이는 경제 활동 여부(Exp(b)=19.58,p=.003)였다 연구결과는 가족과 결혼가치관 교육과 경제활동을 하는 35세에서 39세 미혼여성의 결혼견해에 영향을 미치는 요인을 고려한 저출산 정책이 필요함을 시사한다.

작물의 유황영양에 관한 연구( I ) -포장재배수도의 유황영양실태- (Studies on the sulfur nutrition of crop plants (I) -The nutritional status of sulfur in the field-grown rice plants-)

  • 박훈;김영섭;이춘영
    • Applied Biological Chemistry
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    • 제14권2호
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    • pp.109-116
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    • 1971
  • 기후 토양 시비조건이 다른 수개포장에서 자란 벼의 유황영양상태를 조사한 결과 아래와 같다. 1. 이앙후 30 일경 유황결핍포장의 수도체내 유황의 임계함량(critical percentage)은 0.2%이상인것 같다. 2. 수확기 S 함량평균치는 이삭과 짚에서 각각 0.22% 및 0.43%이고 유안시비는 짚에서의 농도를 더욱 높였다. 3. 볏짚과 이삭의 S 함량비는 유안시비구에서만 위도가 낮을수록 증가하는 경향이나 이삭에의 전이율은 이와 관계없고 시비구에서 평균 26% 무비구에서 29%였다. 4. 유황흡수량은 무비구에서 6kg/10a 시비구에서 10 kg이었다. 5. 부위별 유량함량은 엽신+엽초>간>이삭의 순서이며 어느부위서나 저수답벼에서 높았다.

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Increase of ICSI Efficacy with Hyaluronic Acid-Binding Sperm for Low Aneuploidy Frequency in Pig

  • Park, Chun-Young;Uhm, Sang-Jun;Song, Sang-Jin;Kim, Kwag-Sung;Hong, Seung-Bum;Chung, Kil-Saeng;Lee, Hoon-Taek
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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    • pp.26-26
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    • 2003
  • Hyaluronic acid (HA)-binding sites have been shown the diagnostic potential fur assessment of sperm maturity, which is related to male fertility. This study was designed to evaluate chromosomal patterns in porcine embryos produced by in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with non- or HA-binding sperm (HABS). For binding of sperm with HA, sperm incubated in 10 ${mu}ell$ drop containing HA (0.8 mg/ml)-agarose (0.8%) mixture for 15 min. IVF and ICSI with non- or HA-bound sperm examined with matured oocytes at 44 hr after in vitro maturation. Embryos were cultured in 50 ${mu}ell$ of NCSU 23 containing 0.5% BSA for 5 days and then in 50 ${mu}ell$ of NCSU 23 containing 10% FBS for 2 days. For the evaluation of chromosomal aneuploidies, chromosome 1 sub-metacentric specific probe was used in sperm and embryos by fluorescence in situ hybridization (FISH). The frequency of aneuploidy sperm for chromosome 1 was 6.25%. The significant differences following IVF and ICSI with non- or HA-bound sperm were not observed in blastocyst formation rates (18.6, 23.5, and 23.8%) and cell number (61.8 $\pm$ 12.5, 55.5 $\pm$ 7.3, and 59.3 $\pm$ 9.6). Moreover, the percentage of diploidy in 4-cell stage embryos was 57.1% (IVF), 68.8% (ICSI), and 76.3% (ICSI-HABS). These results suggest that HA-binding sites may be a material for selection of normal sperm for ICSI. Therefore HA selection of normal sperm may be reduce the loss to embryonic mortality prior to embryo transfer in pig.

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