• Title/Summary/Keyword: low velocity

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Pharmacoat Coating in an Aqueous System : The Dissolution Behavior and Reduction in Coating Time

  • Sekigawa Fujio;Muto Hiroaki;Araume Kiyoshi
    • Journal of Pharmaceutical Investigation
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    • v.20 no.3
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    • pp.51-76
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    • 1990
  • It is sometimes said lately that the pH of the human gastric juice is significantly different among individuals. Thus, the dissolution behavior of coated solid dosage forms should preferably be independent of the pH of the test solution. With these points as a background, the effect of pH on the dissolution velocity of coated tablets was studied to compare that of Pharmacoat with other gastric soluble film coating materials. Three viscosity types of Pharmacoat have been available(3, 6 and 15cP) until now. the 6cP type has been considered to be the most suitable for a tablet coating amongst the three types. The 3 cP type with a low degree of polymerization, is capable of providing high concentration, but the film strength is so inferior that sometimes cracking of the film may occur. On the other hand, in the case of the 15cP type, high polymer concentration cannot be achieved because of the high dgree of polymerization, and thus it is uneconomical for coating. Now, there is a strong demand to reduce the coating time even when HPMC is used in the 6cP type in order to reduce the coating cost. In order to improve this problem, we have concentrated our attention on reducing the viscosity value of HPMC to an allowable lower limit from 6cP. As a result of this study, it was found that the reduction of the viscosity value to around 4.5cP enabled the use of a higher solution concentration and an incidental shorter coating time without giving any substantial adverse effects on the properties of coated preparations. These experiment results are presented in the later part of this presentation. Based on this study, we have added the viscosity type of 4.5cP as one of the Pharmacoat products as Pharmacoat-645.

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Adsorption Characteristics of VOCs in Activated Carbon Beds (활성탄 흡착탑을 이용한 휘발성 유기화합물의 흡착특성)

  • Noh, Soon-Young;Kim, Ki-Ho;Choi, Jae-Ho;Han, Sam-Duck;Kil, In-Sub;Kim, Duk-Hyun;Rhee, Young-Woo
    • Journal of Korean Society for Atmospheric Environment
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    • v.24 no.4
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    • pp.455-469
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    • 2008
  • VOCs (Volatile organic compounds) are known as one of the harmful chemicals, causing cancer and global warming. Therefore, the proper control, removal, and reduction of the emission of VOCs are important tasks for the environmental protection. Among the method of VOCs removal activated carbon bed is the most efficient and economical method. In this study, the adsorption performance of toluene gas was investigated using various activated carbons. To find out the adsorption efficiency, the H/D (Height/Diameter) of the activated carbon and GHSV (Gas Hourly Space Velocity) of the toluene gas were manipulated with various conditions. The effect of the temperature, humidity and toluene-MEK-IPA mixed gas on adsorption were also investigated. As a result, a high adsorption performance was found when GHSV is lower at room temperature and low humidity. It was also found that the adsorption efficiency of toluene-MEK-IPA mixed gas system was lower than that of toluene gas system.

Influence of Impact Angle on Deformation in Proximal Femur during Slide Falling (측방 낙상시의 충격 각도가 대퇴골 근위부의 변형에 미치는 영향)

  • 김병수;배태수;김정규;최귀원
    • Journal of Biomedical Engineering Research
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    • v.24 no.3
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    • pp.233-239
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    • 2003
  • Falling related injuries are categorized as the most serious and common medical problems experienced by the elderly, hip joint fracture, one of the most serious consequences of falling in the elderly, occurs in only about 1% of falling. Nevertheless, hip fracture accounts for a considerable part of the disability, death, and medical costs associated with falling. In this study, we considered the impact angle and displacement rate in falling as another factor affecting femoral strength. Using a fresh-frozen human femur, we developed system to simulate the falling condition and then conducted the experiments changing the impact angle (0$^{\circ}$, 15$^{\circ}$, 30$^{\circ}$) of proximal femur. Also, in order to analyze the relative risk due to falling to normal situation in proximal femur, we did the static test simulating the two-legged stance condition. The results showed that the change in impact angle affected the strain distribution in proximal femur, and that a large deformation in femoral neck than in other sites. Furthermore despite low impact velocity, a large deformation in proximal femur occurred in the impact test and different strain distribution was observed compare to the static case.

Study on the measurement of blasting vibration response in construction a subway station at East gate of cultural treasure (지하철건설에 따른 문화재 보호와 동대문역사시공 보고서(1))

  • Choi, Sang-Yol;Ree, Soo-Book;Huh, Ginn;Chai, Soo-Yun
    • Journal of the Korean Professional Engineers Association
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    • v.17 no.3
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    • pp.32-49
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    • 1984
  • The East gate station area is 205M long and 24m deep which is located 13 meter in front of cultural treasure east gate. The area to be excavated by blasting is composed of granite rocks from 10M depth to 25M. Surface earth extends to up 10M depth. This job site has in involves heavy traffic congestion such as over 10,000 cars passing in rush hour where clossing No 1 lint of subway running 3 minitues head way. This east gate station construction is to be executed for the provent of the setting down of underground level and blasting vibration effects to cultural treasure east gate. Therefore, the caltural treasure committee approved this execution subject to the following condition. 1. Subway gelogical foundation and measured natural frequency 2. Execution of water tight wall 3. Sellection and test of damping material for wall and under rail 4. Measurement of monitoring system during the execution 5. Measurement of histogram system The above two projects was carried out by Dr. Kwang team in KAIST and prof, Han in Hanyang University under accadamic study contract. In the blasting work, for the pourpose of reduced vibration and low explosion velocity such as CCR, Kovex slurry. The 2nd, used electrical caps shall be delay cap and M/S caps in multi delay. The 3rd, drilling pattern is bench cut in open cut and applied control blasting in tunnelling and also shall drill anti-vibration holes as line drilling.

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Experimental Study on Effect of Stranded Oil on the Penetration of Particulate Matters in Tidal Flat (연안 조간대에 표착된 기름이 입자상 물질의 토양침투에 미치는 영향의 실험적 연구)

  • Cheong, Cheong-Jo;Lee, Young-Sik
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.10
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    • pp.1030-1034
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    • 2005
  • The purpose of this study was to clarify the penetration behavior of particulate matters by wave and tidal actions in sandy beach located in enclosed bay and to evaluate the effect of stranded oil on penetration of particulate matters. Experiments were rallied out using a model sandy beach facility. The particulate matters penetrated into saturated sediments by wave action from breaking wave run-up point with a semi-circular forming in low energy beach as enclosed bay. On the other hand, the penetration velocity of the particulate matters was to be faster according to the increase of slope and breaking wave height. The particulate matters by tidal action penetrated into the sediments at an angie of 45 degrees in the direction of porous water flow. The stranded oil completely blocked the penetration of the particulate matters into the sediments. These results indicate that the penetrated oil prevents the penetration of the particulate matters into the sediments and, therefore, results in the reduction in the supply of plankton, bacteria and organic detritus for the benthic organisms in the sandy beach.

A Nonlinear Friction Torque Compensation of Servo System with Double Speed Controller (이중 속도 제어 구조에 의한 서보 제어기의 비선형 마찰 토크 보상)

  • Lee Dong-Hee;Choi Cheol;Kim Cheul-U
    • The Transactions of the Korean Institute of Power Electronics
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    • v.9 no.6
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    • pp.612-619
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    • 2004
  • Servo motor systems with ball-screw and timing-belt are widely used in NC, robot, FA and industrial applications. However, the nonlinear friction torque and damping effect in machine elements reduce the control performance. Especially tracking errors in trajectory control and very low velocity control range are serious due to the break-away friction and Stribeck effects. In this paper, a new double speed controller is proposed for compensation of the nonlinear friction torque. The proposed double speed controller has outer speed controller and inner friction torque compensator. The proposed friction torque compensator compensates the nonlinear friction torque with actual speed and speed error information. Due to the actual information for friction torque compensator without parameters and mathematical model of motor, proposed compensator is very simple structure and the stability is very high. The proposed compensator is verified by simulation and experimental results.

Ship Positioning Estimation Using Phased Array Antenna in FMCW Radar System for Small-Sized Ships (소형 선박용 FMCW 레이더 시스템에서의 위상 배열 안테나를 사용한 선박의 위치 추정)

  • Lee, Seongwook;Lee, Seong Ro;Kim, Seong-Cheol
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.40 no.6
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    • pp.1130-1141
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    • 2015
  • Conventionally, a pulse radar is used for middle-sized or large-sized ships to detect other ships or obstacles located at a long distance. However, it is hardly equipped for most of the small-sized ships due to mounting and maintenance costs. Therefore, FMCW(frequency modulated continuous wave) radar is suggested as an alternative for the small-sized ships. Since it operates with low power and has good range resolution for relatively close objects, it is eligible for the small-sized ships. In previously proposed FMCW radar system, it only estimates distance and velocity of a target ship placed in the direction of main beam and is hard to detect several ships simultaneously. Thus, we suggest the method for detecting several ships at the same time by applying MUSIC(multiple signal classification) algorithm to FMCW radar signal received by a phased array antenna. In addition, by combining digital beam forming with the MUSIC algorithm, better angle resolution is achievable.

Application of Artificial Neural Network to the Prediction of Pollutant Concentration in Road Tunnels (인공신경망을 이용한 도로터널 오염물질 농도 예측)

  • Lee, Duck-June;Yoo, Yong-Ho;Kim, Jin
    • Tunnel and Underground Space
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    • v.13 no.6
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    • pp.434-443
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    • 2003
  • In this study, it was purposed to develop the new method for the prediction of pollutant concentration in road tunnels. The new method was the use of artificial neural network with the back-propagation algorithm which can model the non-linear system of tunnel environment. This network system was separated into two parts as the visibility and the CO concentration. For this study, data was collected from two highway road tunnels on Yeongdong Expressway. The tunnels have two lanes with one-way direction and adopt the longitudinal ventilation system. The actually measured data from the tunnels was used to develop the neural network system for the prediction of pollutant concentration. The output results from the newly developed neural network system were analysed and compared with the calculated values by PIARC method. Results showed that the prediction accuracy by the neural network system was approximately five times better than the one by PIARC method. In addition, the system predicted much more accurately at the situation where the drivers have to be stayed for a while in tunnels caused by the low velocity of vehicles.

A Study on the Stability Analysis of the Bank Revetment at Urban Streams in Flood Times (홍수시 도시하천의 호안 안정성 분석에 관한 연구)

  • Kim, Chul;Park, Nam-Hee
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.6
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    • pp.139-145
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    • 2010
  • Recently, close-to-nature stream improvement works have been carried out in urban streams, where eco-friendly bank revetment methods have been adopted. These bank revetment methods are vulnerable to be damaged or washed away by floods compared to the traditional methods which use concrete materials. Damage analysis methods on the urban streams by the floods of severe rain storm are presented. The analysis methods are the graph-using method and the grid method, which are derived from the survey results at Gwangju stream. Damage analysis grid which is intersected velocity grid and material strength grid is the highest correlation with the damage survey grid. The biggest damage on the bank revetments have been occurred around the crossing structures. Big damages have also been occurred in the connection of low water revetment and the terrace land, and around the structures in the terrace land of the stream.

Germination Characteristics and Early Growth of Acer pictum subsp. mono (Maxim.) H. Ohashi by Harvesting Dates (고로쇠나무 종자 수확시기에 따른 발아특성 및 초기생육)

  • Song, Ki Seon;Yoon, Jun Hyuck;Jeon, Kwon Seok;Kim, Chang Hwan;Park, Yong Bae;Kim, Jong Jin
    • Korean Journal of Medicinal Crop Science
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    • v.24 no.1
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    • pp.21-26
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    • 2016
  • Background : Acer pictum is a deciduous tree belonging to the family Aceraceae. This study was conducted to collect basic data on mass propagation techniques by surveying the germination and growth characteristics of A. pictum seeds. Methods and Results : A. pictum seeds were harvested in 2014 on August 19, September 5, September 29 and October 31. The seeds were then sown on the same dates they were harvested. A portion of seeds harvested in August 2014 were stored at low temperatures and subsequently sown on March 11, 2015. The germination rate of A. pictum seeds was highest in seeds that were stored harvested on October 31. Mean germination time (MGT) was shortest and germination velocity (Rs) was fastest in seeds harvested on October 31. Root collar diameter, total root length, and dry weight were also highest from seeds collected October 31. Conclusions : A. pictum seeds harvested on October 31 had highest germination and growth rates compared with seeds harvested on earlier dates. It is expected that these results demonstrating optimum harvesting and sowing dates will be applicable to future seedling production for this tree species.