• Journal of Nutrition and Health
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• 제43권1호
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• pp.46-56
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• 2010

This study was intended to assess the effects of low glycemic index (LGI) nutrition education on dietary management and glycemic control of patients with type 2 diabetes mellitus. The subjects were 48 sex-matched patients with type 2 diabetes mellitus, aged $66.5\;{\pm}\;6.2$ years, visiting a public health center. They were divided into two groups: the control group (males 10, females 14) and the educated group (males 10, females 14). The educated group was provided with a LGI nutrition education program for 7 weeks. The control group was educated only one time for general diabetic education. Anthropometric indices, knowledge and perception of efficacy of low glycemic index carbohydrates, dietary glycemic index (DGI) and glycemic load (DGL), fasting blood glucose, and HbA1c were assessed. In the educated group body weight, body mass index and systolic blood pressure (from $138.0\;{\pm}\;18.9\;mmHg$ to $130.6\;{\pm}\;15.0\;mmHg$) were significantly reduced after the nutrition education (p < 0.05). The scores of knowledge and perception of efficacy of low glycemic index carbohydrates increased significantly in the educated group. Dietary glycemic index and glycemic load of the educated group decreased significantly from $103.4\;{\pm}\;67.6$ to $45.4\;{\pm}\;27.1$ (p < 0.001), and from $173.3\;{\pm}\;135.9$ to $66.8\;{\pm}\;50.4$ (p < 0.001), respectively. Also fasting blood glucose and HbA1c levels of the educated group significantly decreased from $124.5\;{\pm}\;28.8\;mg/dL$ to $96.7\;{\pm}\;21.6\;mg/dL$ (p < 0.001) and from $7.1\;{\pm}\;1.3%$ to $6.4\;{\pm}\;1.2%$ (p < 0.05), respectively. The score of knowledge and perception of efficacy of low glycemic index significantly correlated with fasting blood glucose and HbA1c levels negatively. DGI, DGL and duration of diabetes significantly correlated with HbA1c level positively. From stepwise multiple linear regression analysis, DGI, DGL and the duration of diabetes were extracted as factors influencing HbA1c level of the subjects. The results of this study suggest that low glycemic index nutrition education programs is an effective intervention measure for the glycemic control in type 2 diabetic patients.

• 대한영양사협회학술지
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• 제10권3호
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• pp.322-332
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• 2004

The possibility that high, long-term intake of carbohydrates that are rapidly absorbed as glucose may increase the risk of type 2 diabetes has been long-standing controversy. A high consumption of carbohydrates with a high glycemic index produces greater insulin resistance than did the intake of low glycemic index carbohydrates. This study was designed to evaluate the cabohydrate intake status include glycemic index and correlation carbohydrtae intake status with anthropometry factors & other nutrients in usual diet of the Korean type 2 diabetes mellitus. In 104 tpye 2 diabetes mellitus patients(mean age : 51.8yr, male=44.femal=60), we determined carbohydrte intake status include glycemic index with 24hr recall method and measured anthropometry. Mean daily carbohydrtae intakes and glycemic index were 307.3g(male 323.1g, female 295.5g) and 90.7(male 93.4, female 88.8), respectively. We found a strong and statistically significant association between carbohydrate ratio and glycemic index in obese factors, other nutrient. But carbohydrate intake/kg of body weight was low a significant differences in obese factors, other nutrient. Also glycemic index was effected by total energy intake and carbohydrate ratio than carbohydrate intake/kg of body weight. In conclusion, emphasis for dietary modification should be total energy intake and carbohydrate ratio in diabetes mellitus patient.

• 한방비만학회지
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• 제5권1호
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• pp.121-131
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• 2005

During last few decades dietary guidelines for the weight management mainly have focused on a low-fat, high carbohydrate diet. Carbohydrate was supposed to be low-dense, highly satiating as well as it affects little on the lipogenesis. Although low-fat diet has significant weight-reducing effect, the loss was modest and usually regained after cessation of the diet. Furthermore, low-fat, modest-carbohydrate diet did not impact on the ever increasing rates of overweight and obesity. Alternative approaches include low-carbohydrate diet, high-carbohydrate diet and low-glycemic index diet. Although none of above mentioned diet have sufficient evidence for standard weight management diet, short-term efficacy and safety are being approved continuously. Low-carbohydrate diet contains less than 45% of carbohydrate in daily energy consumption, it is claimed to have more satiating effect and to improve metabolism. However, low compliance due to the limitation of food choice should be considered on prescribing the diet. High-carbohydrate which contains 90% of carbohydrate in total daily energy consumption, is effective in providing satiety and lowering total calorie intake and cholesterol. On the other hand, nutritional unbalance should be took into account. Low-glycemic index diet is based on the theory that contemporary diet contains significantly less fiber and unrefined carbohydrate, therefore insulin secretion is disturbed. Because low glycemic index food slowly increase blood glucose and insulin level, it induces much satiating effect and may decrease calorie ultimate intake. However, poor standardization of glycemic index is one of the main obstacle for the diet to be applied in the clinic. Meanwhile, high fructose food and beverage should be discouraged because it has little satiating effect and may cause insulin resistance. High fiber food is another recommendation for healthy, lean diet.

• Nutrition Research and Practice
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• 제7권5호
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• pp.385-392
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• 2013

Although several studies have assessed the influence of the glycemic index on body weight and blood pressure among adults, limited evidence exists for the pediatric age population. In the current study, we compared the effects of low glycemic index (LGI) diet to the healthy nutritional recommendation (HNR)-based diet on obesity and blood pressure among adolescent girls in pubertal ages. This 10-week parallel randomized clinical trial comprised of 50 overweight or obese and sexually mature girls less than 18 years of age years, who were randomly assigned to LGI or HNR-based diet. Macronutrient distribution was equivalently prescribed in both groups. Blood pressure, weight and waist circumference were measured at baseline and after intervention. Of the 50 participants, 41 subjects (include 82%) completed the study. The GI of the diet in the LGI group was $42.67{\pm}0.067$. A within-group analysis illustrated that in comparison to the baseline values, the body weight and body mass index (not waist circumference and blood pressure) decreased significantly after the intervention in both groups (P = 0.0001). The percent changes of the body weight status, waist circumference and blood pressure were compared between the two groups and the findings did not show any difference between the LGI diet consumers and those in the HNR group. In comparison to the HNR, LGI diet could not change the weight and blood pressure following a 10-week intervention. Further longitudinal studies with a long-term follow up should be conducted in this regard.

• Preventive Nutrition and Food Science
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• 제21권3호
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• pp.165-170
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• 2016

Recent trial results suggest that the consumption of a low glycemic index (GI) diet is beneficial in the prevention of high blood glucose levels. Identifying active hypoglycemic substances in ordinary foods could be a significant benefit to the management of blood glucose. It has been hypothesized that noodles with Bombyx mori powder are a low GI food. We evaluated GI and changes in postprandial glucose levels following consumption of those noodles and compared them with those following consumption of plain wheat flour noodles (control) and glucose (reference) in healthy subjects. Thirteen males (age: $34.2{\pm}4.5years$, body mass index: $23.2{\pm}1.1kg/m^2$) consumed 75 g carbohydrate portions of glucose and the 2 kinds of noodle after an overnight fast. Capillary blood was measured at time 0 (fasting), 15, 30, 45, 60, 90, 120, and 180 min from the start of each food intake. The GI values were calculated by taking the ratio of the incremental area under the blood glucose response curve (IAUC) for the noodles and glucose. There was a significant difference in postprandial glucose concentrations at 30 and 45 min between the control noodles and the noodles with Bombyx mori powder: the IAUC and GI for the noodles with Bombyx mori powder were significantly lower than those for glucose and plain wheat flour noodles. The wheat flour noodles with Bombyx mori powder could help prevent an increase in postprandial glucose response and possibly provide an alternative to other carbohydrate staple foods for glycemic management.

• Nutrition Research and Practice
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• 제7권4호
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• pp.302-308
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• 2013

The emerging role of endothelial inflammation in diabetes has stimulated research interest in the effects of nutrition on related indices. In the current study we investigated whether the nutrient composition of dietary formula as reflected in glycemic index (GI) may be predictive of postprandial endothelial inflammation in non-diabetic subjects. A double-blinded, randomized, crossover study was conducted in non-diabetic subjects (n = 8/group). Each subject consumed three types of diabetes-specific dietary formulas (high-fiber formula [FF], high-monounsaturated fatty acid (MUFA) formula [MF] and control formula [CF]) standardized to 50 g of available carbohydrates with a 1-week interval between each. The mean glycemic index (GI) was calculated and 3-hour postprandial responses of insulin, soluble intercellular adhesion molecule-1 (sICAM-1), nitrotyrosine (NT) and free fatty acids (FFA) were measured. The MF showed the lowest mean GI and significantly low area under the curve (AUC) for insulin (P = 0.038), but significantly high AUCs for sICAM-1 (P<0.001) and FFA (P < 0.001) as compared to the CF and FF. The FF showed intermediate mean GI, but significantly low AUC for NT (P<0.001) as compared to the CF and MF. The mean GI was not positively correlated to any of the inflammatory markers evaluated, and in fact negatively correlated to changes in FFA (r = -0.473, P = 0.006). While the MF with the lowest GI showed the highest values in most of the inflammatory markers measured, the FF with intermediate GI had a modest beneficial effect on endothelial inflammation. These results suggest that nutrient composition of dietary formula as reflected in the GI may differently influence acute postprandial inflammation in non-diabetic subjects.

• 한국한의학연구원논문집
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• 제17권2호
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• pp.173-181
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• 2011

Objective : The purpose of this study is to evaluate the effect of Yuebijiashu-tang with Low-Glycemic Diet on the obesity and to improve the oriental medical methods of treatment in obesity patients. Methods : Forty one patients were classified into four groups(Normal, Overweight, 1st Obesity, 2nd Obesity) by Body Mass Index(BMI). Weight, Body Fat Mass, Body Fat Rate, Waist Hip Rate, BMI and Obesity Index were compared in each group by t-test. Results : In distribution of sex, male was 7(17.1%), female was 34(82.9%). Mean age was 37${\pm}$11 and the patients in twenties were the most. Among four groups, the number of 1st obesity groups was the most. In the change of body composition, the reduction of weight was 6.82${\pm}$2.67kg, the reduction of body fat mass was 5.53${\pm}$2.30kg, the reduction of BMI was $2.51{\pm}0.85kg/m^2$, the reduction of body fat rate was 4.61${\pm}$2.17%, the reduction of waist hip rate was 0.019${\pm}$0.013. Conclusion : This study shows that Yu$\'{e}$biji$\~{a}$sh$\`{u}$-t$\~{a}$ng with low-glycemic diet is effective on weight reduction.

• 대한지역사회영양학회지
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• 제12권2호
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• pp.189-197
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• 2007

Low glycemic index (GI) foods have been reported to be very important in the control of blood glucose levels in diseases such as diabetes mellitus and obesity, which are becoming more prevalent in Korea. Bread consumption at breakfast and as a snack is also on the rise. To provide low GI alternatives, breads supplemented with dietary fibers-fructooligosaccharide (FOS), ground whole rye, and 2 types of resistance starch (RS2 and RS4)-were developed. The GIs for these breads were evaluated with 13 healthy college students (M6, F7) and sensory tests were done. Four kinds of breads were made through the modification of a basic recipe for white bread (the control, B) as follows: for Bf, the entire amount of sugar was replaced with FOS. For Ryef, 50% of the white wheat flower was replaced with roughly ground wholerye (20 mesh: 12-20 mesh = 1 : 3) in addition to replacing sugar with FOS. For RS2f and RS4f, 20% of the white wheat flower was replaced with RS2 or RS4, in addition to replacing sugar with FOS. The overall preference score of Bf was similar to that of B, while those of Ryef, RS2f and RS4f were lower than that of B, but showed the acceptable degree of the overall preference. The glycemic indices of Ryef and RS2f were 46.1 and 45.9 respectively, which were significantly lower than the GI of B, 67.8. The GIs of Bf and RS4f were, however, 66.7 and 80.5 respectively, showing no significant difference compared to B. The glycemic loads for a 30 g serving were 9.5, 5.9, 6.2, 11.0 and 9.0 for B, Bf, Ryef, RS2f and RS4f, respectively. In conclusion, addition of RS2 or roughly ground whole rye to the dough formula significantly lowered the GI. Since the preferences shown for those two breads were acceptable, they may be recommended as a substitute for white bread fir persons who need blood glucose management. More studies on the bread making process are required to improve preference and acceptance. Although GI lowering effects for F and RS4 were not found in this study, further studies are needed to verify their effects.

• Journal of Nutrition and Health
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• 제48권5호
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• pp.398-406
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• 2015

본 연구는 8주 동안 건강한 성인남녀를 대상으로 설탕과 자일로 올리고당 함유비율이 다른 설탕 2종의 혈당 반응을 통한 GI를 비교하여 혈당 저하 효과를 확인하였다. 설탕의 GI는 68.9로 기존의 선행연구에서의 GI와 유사하였다. Xylo 7 (Xylooligosaccaride X2~X7 7% 함유), Xylo 10 (Xylooligosaccaride X2~X7 10% 함유)은 포도당이나 설탕에 비해 섭취 후 최대 혈당 상승량이 낮았으며, Xylo 7과 Xylo 10은 통계적으로 유의하게 최대 혈당 상승량이 적었다. Xylo 7와 Xylo 10의 GI는 각각 54.7, 52.5으로 모두 저GI식품에 해당하여 일반 설탕과 비교하여 혈당상승을 유의하게 억제하였다. 또한 체지방률이 높을수록 Xylo 10의 섭취는 GI를 더 낮추는 경향이었다. 따라서 자일로올리고당 유효성분 X2~X7을 함유한 설탕은 혈당상승을 억제하는 건강 기능성을 갖춘 것으로 사료된다.

• 농촌의학ㆍ지역보건
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• 제39권2호
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• pp.104-115
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• 2014

저당지수 식사는 비만, 당뇨병의 발병 감소 및 심혈관질환의 발생을 감소시키는 효과뿐만 아니라 당뇨병에서 혈당을 개선하는 것으로 알려져 있다. 이런 중요성에 비해 우리나라에서는 일반 성인의 당지수에 대한 인식도를 조사한 연구 자료가 드물다. 이에 본 연구에서는 당지수에 대한 인식도 차이를 정상인과 질환을 가진 환자군으로 나누어 조사하였다. 2011년 9월부터 2012년 2월까지 일개병원 건강증진 센터를 방문한 농촌 지역 사람들을 대상으로 당지수에 대한 인식도와 교육 정도, 교육 참석 의향, 일반적인 지식정도, 저당지수식 실천정도에 관한 내용을 설문지를 이용하여 조사하였다. 당지수에 대한 인식도에서는 당뇨병군이 다른 군에 비해 비교적 잘 알고 있었고, 교육여부도 당뇨병군이 비교적 높게 나타났다. 당지수와 비만, 당뇨병, 고혈압, 고지혈증과의 관련성에 대해 물었을 때도 당뇨병군이 다른 군들에 비해 옳은 응답률의 비율이 높았으나 당지수에 관한 일반적인 지식을 물었을 때는 당뇨병군과 다른 군간의 차이가 없거나 낮은 응답률을 보이기도 하였다. 그러나 전반적으로 당뇨병군을 포함한 모든 군에서 높은 응답률을 보이지 않았다. 평소에 당지수를 고려해서 식사를 하는지와 저당지수식 실천정도를 물었을 때는 당뇨병군이 더 높은 비율을 보였다. 전반적으로 당뇨병군을 제외한 나머지 군에서는 당지수에 대한 인식도가 낮고, 당지수에 대한 올바른 지식이 부족하며 당지수를 고려한 식생활도 잘 이루어지지 않는 것으로 조사되었다. 당뇨병군에서도 저당지수식의 효과 및 당지수 관련 자세한 지식은 부족한 것으로 보였다. 따라서 본 연구를 통해 농촌 지역 당뇨병 환자 뿐 만 아니라 만성질환자나 정상 성인에서도 당지수에 대한 교육이 좀 더 체계적이고 구체적으로 이루어져야 함을 시사하는 바이다.