• Title/Summary/Keyword: loop space

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Conformational Sampling of Flexible Ligand-binding Protein Loops

  • Lee, Gyu-Rie;Shin, Woong-Hee;Park, Hahn-Beom;Shin, Seok-Min;Seok, Cha-Ok
    • Bulletin of the Korean Chemical Society
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    • v.33 no.3
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    • pp.770-774
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    • 2012
  • Protein loops are often involved in diverse biological functions, and some functional loops show conformational changes upon ligand binding. Since this conformational change is directly related to ligand binding pose and protein function, there have been numerous attempts to predict this change accurately. In this study, we show that it is plausible to obtain meaningful ensembles of loop conformations for flexible, ligand-binding protein loops efficiently by applying a loop modeling method. The loop modeling method employs triaxial loop closure algorithm for trial conformation generation and conformational space annealing for global energy optimization. When loop modeling was performed on the framework of ligand-free structure, loop structures within $3\AA$ RMSD from the crystal loop structure for the ligand-bound state were sampled in 4 out of 6 cases. This result is encouraging considering that no information on the ligand-bound state was used during the loop modeling process. We therefore expect that the present loop modeling method will be useful for future developments of flexible protein-ligand docking methods.

Where is the coronal loop plasma located, within a flux rope or between flux ropes?

  • Lim, Daye;Choe, G.S.;Yi, Sibaek
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.1
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    • pp.66.3-67
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    • 2015
  • Without scrutinizing reflection, the plasma comprising a coronal loop is usually regarded to reside within a flux rope. This picture seems to have been adopted from laboratory plasma pinches, in which a plasma of high density and pressure is confined in the vicinity of the flux rope axis by magnetic tension and magnetic pressure of the concave inward magnetic field. Such a configuration, in which the plasma pressure gradient and the field line curvature vector are almost parallel, however, is known to be vulnerable to ballooning instabilities (to which belong interchange instabilities as a subset). In coronal loops, however, ideal MHD (magnetohydrodynamic) ballooning instabilities are impeded by a very small field line curvature and the line-tying condition. We, therefore, focus on non-ideal (resistive) effects in this study. The footpoints of coronal loops are constantly under random motions of convective scales, which twist individual loop strands quite randomly. The loop strands with the axial current of the same direction tend to coalesce by magnetic reconnection. In this reconnection process, the plasma in the loop system is redistributed in such a way that a smaller potential energy of the system is attained. We have performed numerical MHD simulations to investigate the plasma redistribution in coalescence of many small flux ropes. Our results clearly show that the redistributed plasma is more accumulated between flux ropes rather than near the magnetic axes of flux ropes. The Joule heating, however, creates a different temperature distribution than the density distribution. Our study may give a hint of which part of magnetic field we are looking to in an observation.

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Design and Performance Test of a Closed Loop Thermal Control System for Thermal Vacuum Chamber (열진공 챔버용 폐회로 열제어시스템 설계 및 성능평가)

  • Seo, Heejun;Cho, Hyokjin;Park, Sungwook;Moon, Gueewon;Jung, Sanghun;Huh, Hwanil
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.44 no.1
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    • pp.88-97
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    • 2016
  • A closed loop thermal control system simulates space thermal environment to verify the satellites' functionality in extremely cold/hot temperature. It is composed of a cryogenic blower, thermal shroud, heater, cryogenic valves. This paper presents an overview of closed loop thermal control system's design parameter and test results for control parameter. A capacity of blower is calculated through energy balance equation and an advantage/disadvantage for a shroud material and a type was analysed. The thermal control system is controlled by a constant density of fluid in the system. A requested performance of closed loop thermal control system was verified by measuring a homogeneity and stability of shroud through control parameter such as density and RPM of blower.

State-Space Model Identification of Arago's Disk System (아라고 원판 시스템의 상태공간 모델 식별)

  • Kang, Ho-Kyun;Choi, Soo-Young;Choi, Goon-Ho;Park, Ki-Heon
    • Proceedings of the KIEE Conference
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    • 2000.07d
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    • pp.2687-2689
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    • 2000
  • In many cases the systems are so complex that it is not possible to obtain reasonable models using physical insight. Also a model based on physical insight contains a number of unknown parameters even if the structure is derived from physical laws. These problems can be solved by system identification. In this paper, Arago's disk system which has both stable and unstable regions is selected as an example for identification and a state-space model is identified using tailor-made model structure of this system. In stable region, a state-space model of Arago's disk system is identified through open loop experiment and a state-space model of unstable region is identified through closed loop experiment after using fuzzy controller to stabilize unstable system.

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Printed Type Half-wavelength Small Loop Antenna (프린트형 반파장 소형 루프 안테나)

  • Ryu, Hong-Kyun;Woo, Jong-Myung
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2005.11a
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    • pp.245-248
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    • 2005
  • In this paper, small sized half-wavelength circular loop antenna which attached beneath a visor of helmet is designed and fabricated at the resonant frequency of 449MHz. To reduce the size of the antenna, double series-shorted stubs are inserted inside the loop for practical use of a vacant space of loop inside. Also, It is designed for the printed type to install the helmet easily. The size of antenna on helmet is reduced to 87.75%(diameter : 70mm, height :.36mm) compare with general type antenna(diameter : 200mm height 101mm). The return loss, -10dB bandwidth and gain are -13.2dB, 17.6MHz(3.9%), and -1.78dBd. And, radiation pattern is omni-directional pattern at H-plane. Therefore, it can be seen that the half-wavelength circular loop antenna using double series-shorted stubs is proper structure for the miniaturization and the installed antenna of the helmet.

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Design and Implementation of Carrier Recovery Loop for Satellite Telemetry and Tracking & Command (위성 관제용 반송파 복원부 설계 및 구현)

  • Lee, Jung-Su;Oh, Chi-Wook;Seo, Gyu-Jae;Oh, Seung-Han;Chae, Jang-Soo;Myung, Noh-Hoon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.39 no.1
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    • pp.56-62
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    • 2011
  • A Satellite transponder is mounted on the Satellite and performs radio communications with the ground station. A Digital transponder compared to The analog transponder is made easy and accurate performance prediction. Also Modulation Scheme, Data Rate, Loop Bandwidth, Modulation Index and etc. can be changed on orbit, by implementing FPGA can reduce the weight and volume. The core technology of digital transponder is Carrier Recovery loop. Dynamic Range, Frequency Tracking Range, Frequency Tracking Rate and Coherent performance are determined by the performance of the Carrier Recovery loop. In this paper, we proposed the structure of Carrier Recovery loop for the Satellite digital transponder, then tested and verified the structure.

Homing Loop Design for Missiles with Strapdown Seeker (스트랩다운 탐색기 기반 호밍루프 설계)

  • Hong, Ju-Hyeon;Ryoo, Chang-Kyung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.42 no.4
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    • pp.317-325
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    • 2014
  • For a missile with a strapdown seeker, line-of-sight rate for guidance is obtained by compensating the look angle rate from the strapdown seeker by the body angular rate from rate gyros. However, the body angular rate from rate gyros has different signal properties when it compared to the body angular rate implicitly included in the look angle rate. Typically this discrepancy causes instability of homing loop. In this paper, we propose a design method of homing loop where seeker delay is compulsively placed in the output signal of the rate gyros for accordance of both body rates. Also, PID control loop is considered for obtaining stabilized guidance command even though uncertainties of seeker delay is associated. The stability analysis for the linear homing loop before and after the compensation has been done. The stability and performance of the designed terminal homing loop is verified through full nonlinear 6-DOF simulations.

Performance Comparison of Three Different Types of Attitude Control Systems of the Quad-Rotor UAV to Perform Flip Maneuver

  • Lee, Byung-Yoon;Yoo, Dong-Wan;Tahk, Min-Jea
    • International Journal of Aeronautical and Space Sciences
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    • v.14 no.1
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    • pp.58-66
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    • 2013
  • This paper addresses the performance of three different types of attitude control systems for the Quad-rotor UAV to perform the flip maneuver. For this purpose, Quad-rotor UAV's 6-DOF dynamic model is derived, and it was used for designing an attitude controller of the Quad-rotor UAV. Attitude controllers are designed by three different methods. One is the open-loop control system design, another is the PD control system design, and the last method is the sliding mode control system design. Performances of all controllers are tested by 6-DOF simulation. In case of the open-loop control system, control inputs are calculated by the quad-rotor dynamic model and thrust system model that are identified by the thrust test. The 6-DOF realtime simulation environment was constructed in order to verify the performances of attitude controllers.

Robustness of Positive Position Feedback Control in the Independent Modal Space (독립된 모달공간에서 양 위치피드백 제어기법의 강인성)

  • 황재혁;백승호
    • Journal of KSNVE
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    • v.4 no.2
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    • pp.177-185
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    • 1994
  • In this study, the effect of parameter errors on the closed-loop behavior of flexible structure is analyzed for IMSC(Independent Modal Space Control) with PPF(Positive Position Feedback). If the control force designed on the basis of structure model with the parameter errors is applied to control the actual system, the closed-loop performance of the actural system will be degraded depending on the degree of the errors. An asymptotic stability condition has been derived, using Lyapunov approach, which is independent of the dynamic characteristics of the structure being controlled. The extent of deviation of the closed-loop performance from the designed one is also derived and evaluated using operator techniques. It has been found that the extent of the deviation is proportational to the magnitude of the parameter errors, and that the proportional coefficient depends on the control algorithm.

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U-loop emergence on the Sun

  • Magara, Tetsuya
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.1
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    • pp.34.2-34.2
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    • 2011
  • In this talk we explain U-loop emergence, in which U-shaped field lines emerge into the solar surface against gravitational force. In principle, they hardly emerge because mass tends to accumulate at the bottom of U-loops, thereby decreasing buoyancy. A key is found to be the shape of U-loops, that is, if U-loops have a shallow dip whose depth is of the order of the photospheric gravitational scale height, then a diverging flow is generated via a siphon-like mechanism by which the mass accumulated at the dip of the loops is drained out to enhance buoyancy. This successfully makes U-part of the loops emerge against gravity. We also discuss the relation between U-loop emergence and the so-called flux cancellation observed on the Sun in which opposite polarity regions apparently approach together and disappear.

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