• Molecules and Cells
• /
• v.45 no.7
• /
• pp.465-478
• /
• 2022

MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate the expression of target messenger RNA (mRNA) complementary to the 3' untranslated region (UTR) at the post-transcriptional level. Hsa-miR-422a, which is commonly known as miRNA derived from transposable element (MDTE), was derived from short interspersed nuclear element (SINE). Through expression analysis, hsa-miR-422a was found to be highly expressed in both the small intestine and liver of crab-eating monkey. AT-Rich Interaction Domain 5 B (ARID5B) was selected as the target gene of hsa-miR-422a, which has two binding sites in both the exon and 3'UTR of ARID5B. To identify the interaction between hsa-miR-422a and ARID5B, a dual luciferase assay was conducted in HepG2 cell line. The luciferase activity of cells treated with the hsa-miR-422a mimic was upregulated and inversely downregulated when both the hsa-miR-422a mimic and inhibitor were administered. Nuclear factor erythroid-2 (NF-E2) was selected as the core transcription factor (TF) via feed forward loop analysis. The luciferase expression was downregulated when both the hsa-miR-422a mimic and siRNA of NF-E2 were treated, compared to the treatment of the hsa-miR-422a mimic alone. The present study suggests that hsa-miR-422a derived from SINE could bind to the exon region as well as the 3'UTR of ARID5B. Additionally, hsa-miR-422a was found to share binding sites in ARID5B with several TFs, including NF-E2. The hsa-miR-422a might thus interact with TF to regulate the expression of ARID5B, as demonstrated experimentally. Altogether, hsa-miR-422a acts as a super enhancer miRNA of ARID5B by collaborating with TF and NF-E2.

• Journal of Marine Life Science
• /
• v.4 no.2
• /
• pp.53-62
• /
• 2019

Heterotrophic bacteria are a major member of the microbial loop in the marine ecosystem and play an important role in the biogeochemical cycle decomposing organic matter. Therefore study of bacterial variation is important to understand the material cycle and energy flow of marine ecosystems. We investigated the monthly variations of bacteria and environmental factors in the Youngsan River estuary, and the correlation between bacteria and phytoplankton biomass (chlorophyll-a) including size-structure. As a result, bacteria of the Youngsan River estuary were higher in the surface than in the bottom layer, and higher in the summer than in winter. And the closer to the dike, the abundance increased, and it increased to the peaks in August, September, and June 2019 at the station closest to the dike. The chlorophyll-a also increases at the stations and time when the bacterial abundance was high and they correlates positively displaying no difference between size fractions. The results indicate that organic matter derived from phytoplankton has an effect on bacterial variation but no size-dependent effects. In addition, the seasonal pattern of bacteria increasing in proportion to the water temperature suggests the effect of water temperature on the growth of bacteria. No association of bacterial abundance variation with nutrient supply due to freshwater input was observed. In this study, dissolved oxygen was depleted and hypoxia was observed for a short time when a strong stratification was not developed. This may be resulted from the supply of organic matter from phytoplankton and the consumption of oxygen due to bacterial decomposition.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.25 no.4
• /
• pp.222-237
• /
• 2022

This study was performed to predict change of forestland area in future to 2050 based on System Dynamics Model which is based on feedback loop by causal relationship. As forestland area change in the future depends on potential forestland conversion demands, each demand type of forestland conversion such as agricultural, industrial, public and residential/commercial use was modeled using annual GDP, population, number of household, household construction permission area (1981~2019). In results, all of conversion demands would have continuously decreased to 2050 while residential and commercial land would be reduced from 2034. Due to such shortage, eventually, total of forestland in South Korea would have decreased to 6.18 million ha when compared to current 6.29 million ha. Moreover, the forestland conversion to other use types must be occurred continuously in future because most of forestland is owned privately in South Korea. Such steady decrement of forestland area in future can contribute to the shortage of carbon sink and encumber achievement of national carbon-neutral goal to 2050. If forestland conversion would be occurred inevitably in future according to such change trends of all types, improved laws and polices related to forestland should be prepared for planned use and rational conservation in terms of whole territory management. Therefore, it is needed to offer sufficient incentive, such as tax reduction and payment of ecosystem service on excellent forestland protection and maintenance, to private owners for minimizing forestland conversion. Moreover, active afforestation policy and practice have to be implemented on idle land for reaching national goal 'Carbon Neutral to 2050' in South Korea.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
• /
• v.40 no.4
• /
• pp.261-273
• /
• 2022

This study aims to predict the land use demand of Seongnam-city using system dynamics and to simulate the effect of changes in family structure and land use density adjustment policy on land use demand. This study attempted to construct causal loop diagrams and an analysis model. The changes in land use demand over time were predicted through simulation results. As a result of the analysis, as of 2035, an additional supply of 2.08 km² for residential land and 1.36 km² for commercial land is required. Additionally, the current supply area of industrial land can meet the demand. Three policy experiments were conducted by changing the variable values in the basic model. In the first policy experiment, it was found that when the number of household members decreased sharply compared to the basic model, up to 7.99 km² of additional residential land were required. In the second policy experiment, if the apartment floor area ratio was raised from 200% to 300%, it was possible to meet the demand for residential land with the current supply area of Seongnam-city. In the third policy experiment, it was found that even if the average number of floors in the commercial area was raised from four to five and the building-to-land ratio in the commercial area was raised from 80% to 85%, the demand for commercial land exceeded the supply area of the commercial area in Seongnam-city. This study is meaningful in that it proposes a new analytical model for land use demand prediction using system dynamics, and empirically analyzes the model by applying the actual urban planning status and statistics of Seongnam-city.

• KIPS Transactions on Software and Data Engineering
• /
• v.11 no.5
• /
• pp.189-196
• /
• 2022

Skyline query is a scheme for exploring objects that are suitable for user preferences based on multiple attributes of objects. Existing skyline queries return search results as batch processing, but the need for real-time search results has increased with the advent of interactive apps or mobile environments. Online algorithm for Skyline improves the return speed of objects to explore preferred objects in real time. However, the object navigation process requires unnecessary navigation time due to repeated comparative operations. This paper proposes a Pre-processing Online Algorithm for Skyline Query (POA) to eliminate unnecessary search time in Online Algorithm exploration techniques and provide the results of skyline queries in real time. Proposed techniques use the concept of range-limiting to existing Online Algorithm to perform pretreatment and then eliminate repetitive rediscovering regions first. POAs showed improvement in standard distributions, bias distributions, positive correlations, and negative correlations of discrete data sets compared to Online Algorithm. The POAs used in this paper improve navigation performance by minimizing comparison targets for Online Algorithm, which will be a new criterion for rapid service to users in the face of increasing use of mobile devices.

• Journal of the Korean Society of Radiology
• /
• v.16 no.2
• /
• pp.87-94
• /
• 2022

In this study, 61 patients who underwent coronary angiography from March 2018 to August 2019 were divided into Group I (Radial, n=34 patients) and Group II (Femoral, n=27 patients), and compared and analyzed methods using radial and femoral arteries when coronary angiography was performed. As a result of comparative analysis, Catheter usage was reduced in the examination using radial artery, and in the abnormal shape of blood vessels, Loops arterial abnormalities were more in the radial artery (20.6% vs, 0%, p<0.05), and it was found that the abnormal shape of the radial vessels increased with age. 60s, 70s, 80s, 90s or older (0%, 18.2%, 25.0%, 100%)

• 지역과문화
• /
• v.8 no.3
• /
• pp.27-48
• /
• 2021

In recent years, China's tourism performing art in a series of new completion of the project, increase the box office of tourism performing arts industry, higher economic income, at the same time led to the formation of brand of tourism performing arts and has a good reputation, with the regional culture, has a certain role in promoting economic development, including Large scenario experience drama is one of the key projects. Large scenario experience drama is a new form of drama that simulates the space design of real environment and enables the audience to have active experience in visual, auditory, smell, taste, touch and other senses with strong interactivity.Large scenario experience drama are adapted from traditional Chinese culture, regional culture and long-passed stories, and combine high technology such as lighting, sound effects, special effects and 3D effects to make the audience's experience more real.As the first Large scenario experience drama in China, 'You Jian Ping-yao' reflects the profound culture of Shanxi with new forms of expression and creative means, in the form of scene experience and make the audience more intuitive feel the 'Shanxi emotion', 'Shanxi sentiment' and 'Shanxi Morality', carry forward the traditional culture at the same time, also passed the Shanxi ancient and great values, strengthened the drama of China's movie village, impetus the development of the tourism industry in Shanxi, drive the Shanxi region of jingjing, gradually formed a complete industrial chain. However, there are also limitations such as improper plot connection and improper tourist management, which can improve the performance effect through more audience interaction and guidance. Therefore, it can be seen that large-scale situational experience dramas play a great role in promoting the dissemination of traditional culture and values, the development of tourism industry, the formation of regional brand characteristics and economic development. Through these, it can be seen that large-scale situational experience plays have enlightenments such as innovative thinking content, gradually forming an industrial chain closed-loop, and broadening publicity channels for the development of live-action performances.

• Journal of the Korea Society of Computer and Information
• /
• v.27 no.11
• /
• pp.181-190
• /
• 2022

In this paper, we use a LiDAR sensor and an image camera to detect a left-turning waiting vehicle in two ways, unlike the existing image-type or loop-type left-turn detection system, and a left-turn traffic signal corresponding to the waiting length of the left-turning lane. A system that can efficiently assign a system is introduced. For the LiDAR signal transmitted and received by the LiDAR sensor, the left-turn waiting vehicle is detected in real time, and the image by the video camera is analyzed in real time or at regular intervals, thereby reducing unnecessary computational processing and enabling real-time sensitive processing. As a result of performing a performance test for 5 hours every day for one week with an intersection simulation using an actual signal processor, a detection rate of 99.9%, which was improved by 3% to 5% compared to the existing method, was recorded. The advantage is that 99.9% of vehicles waiting to turn left are detected by the LiDAR sensor, and even if an intentional omission of detection occurs, an immediate response is possible through self-correction using the video, so the excessive waiting time of vehicles waiting to turn left is controlled by all lanes in the intersection. was able to guide the flow of traffic smoothly. In addition, when applied to an intersection in the outskirts of which left-turning vehicles are rare, service reliability and efficiency can be improved by reducing unnecessary signal costs.

• Journal of Broadcast Engineering
• /
• v.28 no.1
• /
• pp.145-148
• /
• 2023

Open-loop Octonion space-time block code for 4 transmit antenna system is considered and random phases are applied to 4 transmit antennas for physical layer security. When an illegal hacker estimates the random phases of 1 through 4 transmit antennas with maximum likelihood (ML), this letter analyzes the bit error rate (BER) performances versus signal-to-noise ratio (SNR). And the Octonion code in the literature[1] does not have full orthogonality so, this letter employs the perfect orthogonal Octonion code. When the hacker knows that the random phases are 2-PSK constellations and he should estimate all the 4 random phases, the hacking is impossible until 100dB. When the hacker possibly know that some of the random phases, bit error rate goes down to 10^-3 so, the transmit message could be hacked.

• Analyses & Alternatives
• /
• v.7 no.2
• /
• pp.35-77
• /
• 2023

This study aims to solve the entangled loop between demographic transition (DT) and economic growth by analyzing cross-country data. We undertake a national-level group analysis to verify the compressed transition of demographic variables over time. Assuming that the LA (latecomer advantage) on DT over time exists, we verify that the DT of the latecomer is compressed by providing a formal proof of LA on DT over income. As a DT has the double-kinked functions of income, we check them in multiple aspects: early maturation, leftward threshold, and steeper descent under a contour map and econometric methods. We find that the developing countries (the latecomer) have speedy DT (CDT, compressed DT) as well as speedy income such that DT of the latecomers starts at lower levels of income, lasts for a shorter period, and finishes at the earlier stage of economic development compared to that of developed countries (the early mover). To check the balance of DT, we classify countries into four groups of DT---balanced, slow, unilateral, and rapid transition countries. We identify that the main causes of rapid transition are due to the strong family planning programs of the government. Finally, we check the effect of latecomer's CDT on economic growth inversely: we undertake the simulation of the CDT effect on economic growth and the aging process for the latecomer. A worrying result is that the CDT of the latecomer shows a sharp upturn of the working-age population, followed by a sharp downturn in a short period. Compared to early-mover countries, the latecomer countries cannot buy more time to accommodate the workable population for the period of demographic bonus and prepare their aging societies for demographic onus. Thus, we conclude that CDT is not necessarily advantageous to developing countries. These outcomes of the latecomer's CDT can be re-interpreted as follows. Developing countries need power sources to pump up economic development, such as the following production factors: labor, physical and financial capital, and economic systems. As for labor, the properties of early maturation and leftward thresholds on DTs of the latecomer mean that demographic movement occurs at an unusually early stage of economic development; this is similar to a plane that leaks fuel before or just before take-off, with the result that it no longer flies higher or farther. What is worse, the property of steeper descent represents the falling speed of a plane so that it cannot be sustained at higher levels, and then plummets to all-time lows.