• Korean Journal of Biological Psychiatry
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• v.23 no.4
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• pp.185-192
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• 2016

Objectives Treatment response of bipolar disorders (BDs) to long-term mood stabilizers maintenance has not been well explored because of complicated clinical and treatment courses. This study aims at investigating long-term clinical response of BDs to lithium and/or valproate in a naturalistic setting of a tertiary-care university-affiliated hospital. Methods Subjects were 65 patients with bipolar I (BD-I) disorders who had been treated with lithium and/or valproate for more than two years at single bipolar disorder clinic. Long-term response to the best treatment based on treatment algorithms and the current clinical standard of care was retrospectively evaluated using the Alda Scale and the Clinical Global Impression Scale for use in bi-polar illness (CGI-BP). Patients were classified into full responder and partial/non responder groups based on the total score of the Alda Scale with the cut-off score generated from the frequentist mixture analysis of the authors' previous study. Results The mean duration of treatment with the index medication was 69.2 months. Baseline demographic and clinical characteristics were not different among three mood stabilizer groups (valproate, lithium, and combination groups). Twenty-one subjects were classified into full responder group (32.3%). Treatment response assessed by the Alda Scale and CGI-BP scores was not different between lithium and valproate groups. The Alda Scale scores were well correlated with the CGI-BP scores (p < 0.05). Conclusions One third of the patients showed a full response to the long-term lithium and/or valproate treatment in BD-I. The degree of response was similar between lithium and valproate groups.

• Ocean and Polar Research
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• v.23 no.4
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• pp.433-440
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• 2001

Marine organisms in Antarctica live in an environment which exhibits variability in physical processes over a wide range of temporal scales, from seconds to millennia. This time scale tends to be correlated with the spatial scale over which a given process operates, though this relationship is influenced by biology. The way organisms respond to variability in the physical environment depends on the time-scale of that variability in relation to life-span. Short-term variations are perceived largely as noise and probably have little direct impact on ecology. Of much greater importance to organisms in Antarctica are seasonal and decadal variations. Although seasonality has long been recognised as a key feature of polar environments, the realization that decadal scale variability is important is relatively recent. Long-term change has always been a feature of polar environments and may be a key factor in the evolution of the communities we see today.

• Journal of the Korea Society of Computer and Information
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• v.24 no.5
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• pp.121-130
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• 2019

The purpose of this study was to explore the level of the moral distress for nurses working in long-term care hospitals or nursing homes, and identify factors that influence the moral distress. Data were collected through self-reported questionnaires including the Korean version of Moral Distress Scale-Revised (KMDS-R), Jefferson Empathy Scale for Health professionals (K-JSE-HP), Moral Sensitivity Questionnaire (K-MSQ), and the Hospital Ethical Climate Survey (HECS). A total of 194 nurses from 11 long-term care hospitals or 27 nursing homes completed the structured questionnaires. Data were analyzed using IBM SPSS Statistics version 25. As results, the mean score for moral distress was $73.81{\pm}51.29$ in this study. The moral distress of nurses working at nursing homes was higher than that of nurses working in long-term care hospitals. Among the sub-factors of moral distress, the 'futile care' was the highest score and the 'limit to claim the ethical issue' was the lowest. The main factor affecting moral distress among nurses in this study was the ethical climate of organization. In this paper, we propose that in order to effectively reduce the moral distress of nurses working in a long-term care hospital or a nursing home, it is more impactful to address structural issues related to the caregiver workplace than to adjust individual factors.

• Architectural research
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• v.23 no.2
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• pp.19-28
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• 2021

Reduction in competence makes older adults with dementia more sensitive to the influence of the physical environment. The aim of the longitudinal study was to examine whether residents with dementia in long-term facilities with variability in physical environmental characteristics in Vancouver (N= 11), Canada and Stockholm (N=13), Sweden had a difference in their quality of life (QoL). QoL was assessed using Dementia Care Mapping tool three times over one year for the reliability of data. The results of the study demonstrated that the residents with dementia living in a homelike and positive stimulating setting showed less withdrawn behaviors and a higher level of well-being compared to those in a large-scale institutional setting. This study also found that the residents living in a large-scale institutional environment spent more monotonous times than the other groups, which may be to provision of fewer structured activity programs or less social interaction with neighbors or staff members. Residents living in a large-scale institutional setting in Canada showed so far as five times more agitated/ distressed behaviors and twice more withdrawal compared to the ones living in a small-scale homelike setting in Sweden. The study supports that the large-scale institutional environment was considerably associated with levels of lower quality of life among the residents with dementia.

• Coupled systems mechanics
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• v.7 no.2
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• pp.233-254
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• 2018

In order to reduce the dependency on fossil fuels, a policy to increase the production capacity of wind turbine is set up. This can be achieved with increasing the dimensions of offshore wind turbine blades. However, this increase in size implies serious problems of stability and durability. Considering the cost of large turbines and financial consequences of their premature failure, it is imperative to carry out numerical simulations over long periods. Here, an energy-conserving time-stepping scheme is proposed in order to ensure the satisfying computation of long-term response. The proposed scheme is implemented for three-dimensional solid based on Biot strain measures, which is used for modeling flexible blades. The simulations are performed at full spatial scale. For reliable design process, the wind loads should be represented as realistically as possible, including the fluid-structure interaction (FSI) dynamic effects on wind turbine blades. However, full-scale 3D FSI simulations for long-term wind loading remain of prohibitive computation cost. Thus, the model to quantify the wind loads proposed here is a simple, but not too simple to be representative for preliminary design studies.

• Water Engineering Research
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• v.5 no.2
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• pp.81-99
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• 2004

Long term streamflow regime under virtual climate change scenario was examined. Rainfall forecast simulation of the Canadian Global Coupled Model (CGCM2) of the Canadian Climate Center for modeling and analysis for the IPCC SRES B2 scenario was used for analysis. The B2 scenario envisions slower population growth (10.4 billion by 2010) with a more rapidly evolving economy and more emphasis on environmental protection. The relatively large scale of GCM hinders the accurate computation of the important streamflow characteristics such as the peak flow rate and lag time, etc. The GCM rainfall with more than 100km scale was downscaled to 2km-scale using the space-time stochastic random cascade model. The HEC-HMS was used for distributed hydrologic model which can take the grid rainfall as input data. The result illustrates that the annual variation of the total runoff and the peak flow can be much greater than rainfall variation, which means actual impact of rainfall variation for the available water resources can be much greater than the extent of the rainfall variation.

• Journal of the Korea Society of Computer and Information
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• v.21 no.10
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• pp.157-166
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• 2016

The aims of this study are to contribute to efficient revenue management by analysis of the scale in elderly long-term care facilities. The data was used for input of the elderly long-term care costs Scale, and calculated the staffing standards and social welfare facilities workers with living wage guidelines in the Department of Health and Human Services. Revenue efficiency is the highest order of size are as follows. I8(98 people) \43,517,010, H6(86 people) \36,568,332, G8(78 people) \29,426,532, F8(68 people) \23,227,532, E8(58 people) \19,701,254, D8(48 people) \19,155,187, C6( 36) \14,389,109, B8(28 people) \9,920,031, A8(18 people) \3,721,031. It seems that its revenue efficiency even higher than the larger the scale. Meanwhile, The researchers focused on C6 (36 patients) model. Suggestion of this study are following; First, the arrangement can be provided based on needs of the elderly care facility staffing standards. Secondly, an elderly care facility selected wage guidelines. Thirdly, the elderly efficiency guidelines established by the size of a nursing facility. This study and other financial income factor are not the applicable limits.

• Journal of Korean Neurosurgical Society
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• v.29 no.4
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• pp.514-520
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• 2000

Objective : Stereotactic psychosurgery is known as one of effective means of treating in some medically intractable psychiatric illness. However, it is unfamiliar and it's long-term clinical result has not reported in our country. The authors evaluated its long-term results of pscychosurgery and discussed its neuroanatomical basis. Methods : Since 1993, eight patients underwent stereotactic psychosurgery for medically intractable psychiatric illnesses. All were referred from psychiatrist of these disorders, one was aggressive behavior, five were obsessive-compulsive disorders(OCD), and two were depression with anxiety disorders. Bilateral amygdalotomy and subcaudate tractotomy were done for aggressive behavior, and limbic leukotomy was done for OCD and depression with anxiety. The results of OCD were evaluated with with YBOCS(Yale-Brown obsessive compulsive scale) and VAS (visual analogue scale), CGI(clinical global impairment) in OCD, and OAS(overt aggression scale), MMS, WAIS were checked for the evaluation of aggressive behavior. Hamilton depression scale(HAMD) was used for evaluation of depression. Ventriculography was used in the first five patients and MR-guided stereotaxy was used in recent three cases for localization of target. The lesions were made with radiofrequency lesion generator. Results : With long-term follow up(mean 45 months) in five OCDs, mean YBOCS declined from 34 to 3(n=5). All returned to previous social life. In OAS scores of aggressive behavior during six-year follow up, scores declined from 8 to 2 with clinical improvement. In two patients with depression with anxiety, HAMD declined from 28.5 to 16.5(n=2). There was no operative mortality and no significant morbidity except one case of mild transient urinary incontinence. Conclusion : With these long-term results, authors assumed that stereotactic psychosurgery could be one of safe and effective mtherapeutic methods in several medically intractable psychiatric illness.

• Korea Trade Review
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• v.46 no.3
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• pp.65-79
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• 2021

This paper investigates how corporate governance characteristics are related to long-term corporate survival in an emerging economy. We used the data of 311 companies listed on the Korean Stock Exchange (KSE) in 1979 and examined the survival chances of those companies through the IMF crisis in 1998, upon governance characteristics that are expected to increase long-term strategic orientations. We utilized Cox regression model for the analysis. The results indicate that firms with particular governance characteristics that may be tied to CEO's long-term orientations show higher long-term survivability. Specifically, the probability of a firm's long-term survival is increased when founding family ownership is sustained, the company ownership is concentrated, and the CEO is the largest shareholder. This study has significance in that it is one of initial tries to examine the impact of corporate governance on long-term corporate survival with large scale statistical analysis. Also, the study findings provide some clues as to why the portion of family firms in emerging economies is continuously increased, thus providing meaningful insights to corporate governance literature.

• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.101-101
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• 2020

Traditional stochastic simulation of hydroclimatological variables often underestimates the variability and correlation structure of larger timescale due to the difficulty in preserving long-term memory. However, the Long Short-Term Memory (LSTM) model illustrates a remarkable long-term memory from the recursive hidden and cell states. The current study, therefore, employed the LSTM model in stochastic generation of hydrologic and climate variables to examine how much the LSTM model can preserve the long-term memory and overcome the drawbacks of conventional time series models such as autoregressive (AR). A trigonometric function and the Rössler system as well as real case studies for hydrological and climatological variables were tested. Results presented that the LSTM model reproduced the variability and correlation structure of the larger timescale as well as the key statistics of the original time domain better than the AR and other traditional models. The hidden and cell states of the LSTM containing the long-memory and oscillation structure following the observations allows better performance compared to the other tested conventional models. This good representation of the long-term variability can be important in water manager since future water resources planning and management is highly related with this long-term variability.