• Title/Summary/Keyword: log-rank score

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Change-point Estimation based on Log Scores

  • Kim, Jaehee;Seo, Hyunjoo
    • Communications for Statistical Applications and Methods
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    • v.9 no.1
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    • pp.75-86
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    • 2002
  • We consider the problem of estimating the change-point in mean change model with one change-point. Gombay and Huskova(1998) derived a class of change-point estimators with the score function of rank. A change-point estimator with the log score function of rank is suggested and is shown to be involved in the class of Gombay and Huskova(1988). The simulation results show that the proposed estimator has smaller rose, larger proportion of matching the true change-point than the other estimators considered in the experiment when the change-point occurs in the middle of the sample.

Comparison of Change-point Estimators with Scores

  • Kim, Jae-Hee;Seo, Hyun-Joo
    • Journal of the Korean Data and Information Science Society
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    • v.13 no.1
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    • pp.165-175
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    • 2002
  • We consider the problem of estimating the change-point in mean change model with the one change-point. Lombard (1987) suggested change-point estimation based on score functions. Gombay and Huskova (1998) derived a class of change-point estimators with the score function of rank. Various change-point estimators with the log score functions of ranks are suggested and compared via simulation.

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Efficient Score Estimation and Adaptive Rank and M-estimators from Left-Truncated and Right-Censored Data

  • Chul-Ki Kim
    • Communications for Statistical Applications and Methods
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    • v.3 no.3
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    • pp.113-123
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    • 1996
  • Data-dependent (adaptive) choice of asymptotically efficient score functions for rank estimators and M-estimators of regression parameters in a linear regression model with left-truncated and right-censored data are developed herein. The locally adaptive smoothing techniques of Muller and Wang (1990) and Uzunogullari and Wang (1992) provide good estimates of the hazard function h and its derivative h' from left-truncated and right-censored data. However, since we need to estimate h'/h for the asymptotically optimal choice of score functions, the naive estimator, which is just a ratio of estimated h' and h, turns out to have a few drawbacks. An altermative method to overcome these shortcomings and also to speed up the algorithms is developed. In particular, we use a subroutine of the PPR (Projection Pursuit Regression) method coded by Friedman and Stuetzle (1981) to find the nonparametric derivative of log(h) for the problem of estimating h'/h.

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NONPARAMETRIC ONE-SIDED TESTS FOR MULTIVARIATE AND RIGHT CENSORED DATA

  • Park, Hyo-Il;Na, Jong-Hwa
    • Journal of the Korean Statistical Society
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    • v.32 no.4
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    • pp.373-384
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    • 2003
  • In this paper, we formulate multivariate one-sided alternatives and propose a class of nonparametric tests for possibly right censored data. We obtain the asymptotic tail probability (or p-value) by showing that our proposed test statistics have asymptotically multivariate normal distributions. Also, we illustrate our procedure with an example and compare it with other procedures in terms of empirical powers for the bivariate case. Finally, we discuss some properties of our test.

A Test Procedure for Right Censored Data under the Additive Model

  • Park, Hyo-Il;Hong, Seung-Man
    • Communications for Statistical Applications and Methods
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    • v.16 no.2
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    • pp.325-334
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    • 2009
  • In this research, we propose a nonparametric test procedure for the right censored and grouped data under the additive hazards model. For deriving the test statistics, we use the likelihood principle. Then we illustrate proposed test with an example and compare the performance with other procedure by obtaining empirical powers. Finally we discuss some interesting features concerning the proposed test.

The Predictive Values of Pretreatment Controlling Nutritional Status (CONUT) Score in Estimating Short- and Long-term Outcomes for Patients with Gastric Cancer Treated with Neoadjuvant Chemotherapy and Curative Gastrectomy

  • Jin, Hailong;Zhu, Kankai;Wang, Weilin
    • Journal of Gastric Cancer
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    • v.21 no.2
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    • pp.155-168
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    • 2021
  • Purpose: Previous studies have demonstrated the usefulness of the controlling nutritional status (CONUT) score in nutritional assessment and survival prediction of patients with various malignancies. However, its value in advanced gastric cancer (GC) treated with neoadjuvant chemotherapy and curative gastrectomy remains unclear. Materials and Methods: The CONUT score at different time points (pretreatment, preoperative, and postoperative) of 272 patients with advanced GC were retrospectively calculated from August 2004 to October 2015. The χ2 test or Mann-Whitney U test was used to estimate the relationships between the CONUT score and clinical characteristics as well as short-term outcomes, while the Cox proportional hazard model was used to estimate long-term outcomes. Survival curves were estimated by using the Kaplan-Meier method and log-rank test. Results: The proportion of moderate or severe malnutrition among all patients was not significantly changed from pretreatment (13.5%) to pre-operation (11.7%) but increased dramatically postoperatively (47.5%). The pretreatment CONUT-high score (≥4) was significantly associated with older age (P=0.010), deeper tumor invasion (P=0.025), and lower pathological complete response rate (CONUT-high vs. CONUT-low: 1.2% vs. 6.6%, P=0.107). Pretreatment CONUT-high score patients had worse progression-free survival (P=0.032) and overall survival (OS) (P=0.026). Adjusted for pathologic node status, the pretreatment CONUT-high score was strongly associated with worse OS in pathologic node-positive patients (P=0.039). Conclusions: The pretreatment CONUT score might be a straightforward index for immune-nutritional status assessment, while being a reliable prognostic indicator in patients with advanced GC receiving neoadjuvant chemotherapy and curative gastrectomy. Moreover, lower pretreatment CONUT scores might indicate better chemotherapy responses.

Color Space Exploration and Fusion for Person Re-identification (동일인 인식을 위한 컬러 공간의 탐색 및 결합)

  • Nam, Young-Ho;Kim, Min-Ki
    • Journal of Korea Multimedia Society
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    • v.19 no.10
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    • pp.1782-1791
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    • 2016
  • Various color spaces such as RGB, HSV, log-chromaticity have been used in the field of person re-identification. However, not enough studies have been done to find suitable color space for the re-identification. This paper reviews color invariance of color spaces by diagonal model and explores the suitability of each color space in the application of person re-identification. It also proposes a method for person re-identification based on a histogram refinement technique and some fusion strategies of color spaces. Two public datasets (ALOI and ImageLab) were used for the suitability test on color space and the ImageLab dataset was used for evaluating the feasibility of the proposed method for person re-identification. Experimental results show that RGB and HSV are more suitable for the re-identification problem than other color spaces such as normalized RGB and log-chromaticity. The cumulative recognition rates up to the third rank under RGB and HSV were 79.3% and 83.6% respectively. Furthermore, the fusion strategy using max score showed performance improvement of 16% or more. These results show that the proposed method is more effective than some other methods that use single color space in person re-identification.

A Comparison Study of the Test for Right Censored and Grouped Data

  • Park, Hyo-Il
    • Communications for Statistical Applications and Methods
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    • v.22 no.4
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    • pp.313-320
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    • 2015
  • In this research, we compare the efficiency of two test procedures proposed by Prentice and Gloeckler (1978) and Park and Hong (2009) for grouped data with possible right censored observations. Both test statistics were derived using the likelihood ratio principle, but under different semi-parametric models. We review the two statistics with asymptotic normality and consider obtaining empirical powers through a simulation study. The simulation study considers two types of models the location translation model and the scale model. We discuss some interesting features related to the grouped data and obtain null distribution functions with a re-sampling method. Finally we indicate topics for future research.

Longitudinal Relationships between Cigarette Smoking and Increases Risk for Incident Metabolic Syndrome: 16-year Follow-up of the Korean Genome and Epidemiology Study (KOGES)

  • Sang Shin Pyo
    • Biomedical Science Letters
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    • v.29 no.4
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    • pp.355-362
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    • 2023
  • This study aimed to determine whether smoking affects the metabolic syndrome and its components through long-term follow-up. Of the 10,030 cohort subjects in the community-based Korean Genome and Epidemiology Study (KoGES) from 2001 to 2018, 2,848 people with metabolic syndrome and 4,854 people with insufficient data for analysis were excluded for this study. The study population comprised 2,328 individuals (1,123 men, 1,205 women) who were eligible for inclusion. The mean age of the participants was 49.2±7.5 years, and 21.9% were current smoker. In log rank test, current smoker had a significantly higher cumulative incidence of metabolic syndrome compared with non smoker (P<0.001). In the Cox proportional hazards model adjusted for key variables, metabolic syndrome (hazard ratio [HR] 1.57, P<0.001), high fasting glucose (HR 1.40, P<0.01), hypertriglyceridemia (HR 1.60, P<0.001), low HDL-cholesterol (HR, 1.30, P<0.01), and abdominal obesity (HR 1.32, P<0.01) in current smoker compared with non smoker were statistically significant, respectively, but not hypertension (HR 1.00, P>0.05). After adjustment for confounders, the time (P-time<0.001) and group (P-group<0.001) effects on metabolic syndrome score change were statistically significant. Furthermore, the interaction analysis of time and smoking group on the change in metabolic syndrome score was statistically significant (P-interaction<0.001). In long-term follow-up, smoking worsens metabolic syndrome.

CT-Based Leiden Score Outperforms Confirm Score in Predicting Major Adverse Cardiovascular Events for Diabetic Patients with Suspected Coronary Artery Disease

  • Zinuan Liu;Yipu Ding;Guanhua Dou;Xi Wang;Dongkai Shan;Bai He;Jing Jing;Yundai Chen;Junjie Yang
    • Korean Journal of Radiology
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    • v.23 no.10
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    • pp.939-948
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    • 2022
  • Objective: Evidence supports the efficacy of coronary computed tomography angiography (CCTA)-based risk scores in cardiovascular risk stratification of patients with suspected coronary artery disease (CAD). We aimed to compare two CCTA-based risk score algorithms, Leiden and Confirm scores, in patients with diabetes mellitus (DM) and suspected CAD. Materials and Methods: This single-center prospective cohort study consecutively included 1241 DM patients (54.1% male, 60.2 ± 10.4 years) referred for CCTA for suspected CAD in 2015-2017. Leiden and Confirm scores were calculated and stratified as < 5 (reference), 5-20, and > 20 for Leiden and < 14.3 (reference), 14.3-19.5, and > 19.5 for Confirm. Major adverse cardiovascular events (MACE) were defined as the composite outcomes of cardiovascular death, nonfatal myocardial infarction (MI), stroke, and unstable angina requiring hospitalization. The Cox model and Kaplan-Meier method were used to evaluate the effect size of the risk scores on MACE. The area under the curve (AUC) at the median follow-up time was also compared between score algorithms. Results: During a median follow-up of 31 months (interquartile range, 27.6-37.3 months), 131 of MACE were recorded, including 17 cardiovascular deaths, 28 nonfatal MIs, 64 unstable anginas requiring hospitalization, and 22 strokes. An incremental incidence of MACE was observed in both Leiden and Confirm scores, with an increase in the scores (log-rank p < 0.001). In the multivariable analysis, compared with Leiden score < 5, the hazard ratios for Leiden scores of 5-20 and > 20 were 2.37 (95% confidence interval [CI]: 1.53-3.69; p < 0.001) and 4.39 (95% CI: 2.40-8.01; p < 0.001), respectively, while the Confirm score did not demonstrate a statistically significant association with the risk of MACE. The Leiden score showed a greater AUC of 0.840 compared to 0.777 for the Confirm score (p < 0.001). Conclusion: CCTA-based risk score algorithms could be used as reliable cardiovascular risk predictors in patients with DM and suspected CAD, among which the Leiden score outperformed the Confirm score in predicting MACE.