• 정보저장시스템학회:학술대회논문집
• /
• 2005.10a
• /
• pp.185-189
• /
• 2005

We reported here nano-scale electrical phase-change recording in amorphous $Ge_2Sb_2Te_5$ media using an atomic force microscope (AFM) having conducting probes. In recording process, a pulse voltage is applied to the conductive probe that touches the media surface to change locally the electrical resistivity of a film. However, in contact operation, tip/media wear and contamination could major obstacles, which degraded SNR, reproducibility, and lifetime. In order to overcome tip/media wear and contamination in contact mode operation, we adopted the W incorporated diamond-like carbon (W-DLC) films as a protective layer. Optimized mutilayer media were prepared by a hybrid deposition system of PECVD and RF magnetron sputtering. When suitable electrical pulses were applied to media through the conducting probe, it was observed that data bits as small as 25 nm in diameter have been written and read with good reproducibility, which corresponds to a data density of $1 Tbit/inch^2$. We concluded that stable electrical phase-change recording was possible mainly due to W-DLC layer, which played a role not only capping layer but also resistive layer.

• Nuclear Engineering and Technology
• /
• v.45 no.1
• /
• pp.67-72
• /
• 2013

Stress corrosion cracking (SCC) behaviors of Alloy 690 were studied in lead-containing aqueous alkaline solutions using the slow strain rate tension (SSRT) tests in 0.1M and 2.5M NaOH with and without PbO at $315^{\circ}C$. The side and fracture surfaces of the alloy were then examined using scanning electron microscopy after the SSRT test. Microstructure and composition of the surface oxide layer were analyzed by using a field emission transmission electron microscopy, equipped with an energy dispersive X-ray spectroscopy. Even though Alloy 690 was almost immune to SCC in 0.1M NaOH solution, irrespective of PbO addition, the SCC resistance of Alloy 690 decreased in a 2.5M NaOH solution and further decreased by the addition of PbO. Based on thermodynamic stability and solubility of oxide, high Cr of 30wt% in the Alloy 690 is favorable to SCC in mild alkaline and acidic solutions whereas the SCC resistance of high Cr Alloy 690 is weakened drastically in the strong alkaline solution where the oxide is not stable any longer and solubility is too high to form a passive oxide locally.

• Journal of the Korean Institute of Telematics and Electronics B
• /
• v.31B no.8
• /
• pp.74-86
• /
• 1994

In this paper a hierarchical stereo matching algorithm to obtain the disparity in wavelet transformed domain by using locally adaptive window and weights is proposed. The pyramidal structure obtained by wavelet transform is used to solve the loss of information which the conventional Gaussian or Laplacian pyramid have. The wavelet transformed images are decomposed into the blurred image the horizontal edges the vertical edges and the diagonal edges. The similarity between each wavelet channel of left and right image determines the relative importance of each primitive and make the algorithm perform the area-based and feature-based matching adaptively. The wavelet transform can extract the features that have the dense resolution as well as can avoid the duplication or loss of information. Meanwhile the variable window that needs to obtain precise and stable estimation of correspondense is decided adaptively from the disparities estimated in coarse resolution and LL(low-low) channel of wavelet transformed stereo image. Also a new relaxation algorithm that can reduce the false match without the blurring of the disparity edge is proposed. The experimental results for various images show that the proposed algorithm has good perfpormance even if the images used in experiments have the unfavorable conditions.

• Tuberculosis and Respiratory Diseases
• /
• v.67 no.5
• /
• pp.449-453
• /
• 2009

Desmoid tumor (fibromatosis) is a histologically benign fibrous neoplasm showing locally infiltrating growth. This type of tumor commonly occurs in the abdomen, but intrathoracic desmoid tumor is uncommon. To date, 12 cases of intrathoracic desmoid tumor protruding into the pleural cavity, radiologically mimicking pleural masses, have been reported. Here, we report on a case of intrathoracic desmoid tumor protruding into the pleural cavity, and partially covered by parietal pleura. The main preoperative differential diagnoses included pleural solitary fibrous tumor, inflammatory pseudotumor or malignant mesothelioma. A near-total mass excision was performed. Pathologically, the tumor was composed of a paucicellular arrangement of spindle-shaped cells with fibromyxoid stroma. The resection margin was partially involved with spindle cells present. On histochemical staining, the spindle cells were strongly positive for vimentin and negative for CD34, consistent with a desmoid tumor. The patient was stable without further adjuvant treatment during 6-years of follow-up.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2012.05a
• /
• pp.249-252
• /
• 2012

Structural design of the injector head part of a 7ton class thrust chamber was preformed. Structural stability of an injector head part is a very important factor for a thrust chamber of a liquid rocket engine because it is loaded by high pressure of liquid oxidizer and fuel in addition to thrust load. Structural design requirements were first defined to design the injector head part of the 7ton class thrust chamber and the basic configuration was designed on the basis of the design requirements. A high strength steel that has been locally developed was applied to the injector head part of the thrust chamber. A total of twelve design configurations have been analyzed to select structurally the most stable design configuration.

• Advances in aircraft and spacecraft science
• /
• v.9 no.1
• /
• pp.59-68
• /
• 2022

The physical and mathematical foundations of the heat-shielding composite materials functioning under the conditions of aerodynamic heating of aircraft, as well as under the conditions of the point effect of high-energy radiation are considered. The problem of deformation of a thin shallow shell under the action of a local temperature field is approximately solved. Such problems arise, for example, in the case of local destruction of heat-protective coatings of aircraft shells. Then the aerodynamic heating acts directly on the load-bearing shell of the structure. Its destruction inevitably leads to the death of the entire aircraft. A methodology has been developed for the numerical solution of the entire complex problem on the basis of economical absolutely stable numerical methods. Multiple results of numerical simulation of the thermal state of the locally heated shallow shell under conditions of its thermal destruction at high temperatures have been obtained.

• Structural Engineering and Mechanics
• /
• v.84 no.2
• /
• pp.269-283
• /
• 2022

In this paper, a particular type of all-steel HSS brace members with a locally reduced cross-sectional area was experimentally and numerically investigated. The brace member was strengthened against local buckling with inner and outer boxes in the reduced area. Four single-span braced frames were tested under cyclic lateral loadings. Specimens included a simple steel frame with a conventional box-shaped brace and three other all-steel reduced section buckling-restrained braces. After conducting the experimental program, numerical models of the proposed brace were developed and verified with experimental results. Then the length of the proposed fuse was increased and its effect on the cyclic behavior of the brace was investigated numerically. Eventually, the brace was detailed with a fuse-to-brace length of 30%, as well as the cross-sectional area of the fuse-to-brace of 30%, and the cyclic behavior of the system was studied numerically. The study showed that the proposed brace is stable up to a 2% drift ratio, and the plastic cumulative deformation requirement of AISC (2016) is easily achieved. The proposed brace has sufficient ductility and stability and is lighter, as well as easier to be fabricated, compared to the conventional mortar-filled BRB and all-steel BRB.

• Tuberculosis and Respiratory Diseases
• /
• v.53 no.4
• /
• pp.369-378
• /
• 2002

Background : The effects of chemotherapy on pulmonary function are mainly a reduced diffusion capacity and a restrictive ventilatory impairment. Exercise can expose cardiovascular and pulmonary abnormalities not evident at rest. Exercise related cardiopulmonary function is important in patients with malignant disease as a determinant of quality of life. We performed this study to evaluate the changes of body composition and cadiopulmonary exercise perfoemance of patients with locally advanced, non-small cell, lung cancer (NSCLC) before and after chemotherapy. Methods : We evaluated resting pulmonary function, body composition, physiologic performance status, and cardiopulmonary exercise function in 11 patients with locally advanced NSCLC, at diagnosis and prior to the fourth cycle of chemotherapy. Results : After chemotherapy, 4 patients (36.4%) showed partial response and 7 (63.4%) had stable disease. After chemotherapy, diffusion capacity of the lung for carbon monoxide was reduced ($89.7{\pm}34.1%$, vs. $71.9{\pm}20.5%$) but not significantly. There were no significant changes in body composition or the state of physiologic performance after chemotherapy. There was a significant impairment of cardiopulmonary exercise tolerance in patients with NSCLC, evidenced by a reduction of maximal oxygen uptake ($VO_2$max, ml/kg/min, $17.9{\pm}2.6$ : $12.6{\pm}6.1$, <0.05) and $O_2$pulse ($O_2$ pulse, ml/beat, $7.0{\pm}1.7$, $5.2{\pm}2.1$, <0.05). Conclusion : Systemic chemotherapy resulted in a loss of cardiopulmonary exercise function in patients with locally advanced NSCLC within the short-term period, but not a physiologic change of body composition within the same period.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.11
• /
• pp.4791-4795
• /
• 2015

Purpose: This study was conducted to observe the efficacy and safety of pemetrexed based chemotherapy in treating patients with locally advanced or metastatic cancers as first-line, second-line or third-line therapy. Materials and Methods: From May 2011 to January 2015, we recruited 29 patients with advanced breast cancer, 19 patients with advanced ovary cancer, 17 patients with advanced esophageal cancer,5 patients with advanced gallbladder cancer,5 patients with advanced cervical cancer and 1 patient with advanced tongue cancer in Jiangsu Cancer Hospital and Research Institute.All of them were pathologically confirmed and treated with pemetrexed based chemotherapy. After two cycles of treatment,efficacy and safety can be evaluated. Results: For pemetrexed based regimens,including 76 patients with 6 kinds of advanced cancer were considered eligible for inclusion. Complete remission represents CR, partial remission represents PR, stable disease represents SD, progressive disease represents PD. Among 29 patients with advanced breast cancer, 4 patients chose pemetrexed based regimens as second-line treatment,1 of them was PR,the other 3 got SD. The last 25 patients made use of this chemotherapy as third-line treatment, except one patient could not be assessed, 2 of them got PR,6 of them got SD,the remaining 16 of them finally were PD.19 patients with advanced ovary cancer,5 patients used this regimens as second-line treatment, 3 of them got PD,the remaining patients got SD, respectively. The last 14 patients made use of pemetrexed based regimens as third-line treatment,. RR (CR+PR) was 28.5%. Among 17 patients with advanced esophageal cancer, 2 patients made use of pemetrexed based regimens as first-line treatment,both of them got PR.4 of them used this chemotherapy as second-line regimen, except 2 patients could not be assessed,the remaining 2 was PD at last. The last 11 patients was third-line users, RR (CR+PR) was 18.2%. Among 5 patients with advanced gallbladder cancer, pemetrexed based regimens was used in 1 patient as first-line treatment and 1 patient as second-line treatment. The curative effect was SD and PD, respectively. 3 patients accepted pemetrexed based regimens as third-line treatment, 2 of them got PD as results and another was SD. Among 5 patients with advanced cervical cancer, just 1 patient adopted pemetrexed based regimens as first-line treatment, whose curative effect was PR.2 patients chose this chemotherapy regimens as second-line treatment. Both of them got PD as their consequence. The last 2 patients made use of the regimens as third-line treatment, the effect of them was PD and SD, respectively. The one who with advanced tongue cancer, pemetrexed based regimens was used as second-line treatment, and the consequence was PD. About 71.1% patients experienced bone marrow suppression. Among them, 5 patients reached 4 grade. Other toxicity of pemetrexed were neurotoxicity, fatigue, diarrhea, dysphagia and vomiting. No treatment related death occurred with pemetrexed-based treatment. Conclusions: Pemetrexed based chemotherapy has considerable effect in patients with advanced cancers such as breast cancer,esophageal cancer and ovary cancer. More randomly clinical trials are needed to verify the results.

• Korean Journal of Bronchoesophagology
• /
• v.15 no.2
• /
• pp.49-56
• /
• 2009

Purpose : To evaluate the treatment outcome for patients with locally advanced, unresectable esophageal cancer treated with relatively high dose radiation therapy(RT). Materials and Methods : From January 2000 to December 2008, 32 patients with locally advanced unresectable or medically inoperable esophageal cancer were treated with radiation therapy(RT) with or without concurrent chemotherapy. Ten patients were excluded from analysis because of distant metastasis and drop off. Patient distributions according to AJCC stages II, III IVa were 7(31.8%), 12(54.6%), 3(13.6%) respectively. The locations of tumor were cervical/upper thorax 3 (13.6%), mid thorax 13(59.1%), and lower thorax/abdominal 6(27.3%), respectively. Eleven patients received RT only, and 11 patients received cisplatin based concurrent chemoradiotherapy(CCRT). Median radiation dose was 65 Gy(range 57.6~72 Gy). Results : The median follow-up was 9.1 months(range 1.9~43.8 months). The response rates for complete response, Partial response, stable disease and Persistent disease were 6(27.3%), 11(50.0%), 4(18.2%) and 1(4.5%), respectively. Two patients(9.1%) suffered from esophageal stenosis and stents were inserted. Two patients(9.1%) had Grade 3 radiation pneumonitis and one of them expired due to acute respiratory distress syndrome(ARDS) at 36 days after completion of radiation therapy. The recurrence rate was 11(50.0%). The patterns of recurrence were persistent disease and local progression in 5(22.7%), local recurrence 3(13.7%) and concomitant local and distant recurrence in 3(13.7%). The overall survival(OS) rate was 32.1% at 2 years and 21.4% at 3 years(median 12.0 months). Disease free survival(DFS) rate was 17.3% at 2 and 3 years. All patients who had no dysphagia at diagnosis showed complete response after treatment and 100% OS at 3 years(p=0.0041). The OS for above 64.8 Gy group and 64.8 Gy or below group at 3 years were 60.6% and 9.1%(p=0.1341). The response to treatment was the only significant factor affecting OS(p=0.004). Conclusion : Relatively high dose radiation therapy in unresectable esophageal cancer tended to have a better outcome without increased complication rate. Further study with more patients is warranted to justify improved result.