• Title/Summary/Keyword: local Optimum

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A Study on the Optimum Disaster Mitigation Activity to Establish the Early Counter System on the Industrial Accidents (산업체재난 조기 대응체계 구축을 위한 최적 재해경감활동 방안 연구)

  • Lee, Keun-Jae;Yoon, Myong-O;Lee, Won-Ho
    • Fire Science and Engineering
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    • v.24 no.2
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    • pp.9-20
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    • 2010
  • This study indicates direction on establishment of the operational plan for disaster mitigation and its implementation for maintaining business continuity of the local company of the first step, and seeks plans for maintaining their continuity through the establishment of early counter system constructed for achieving lasting safe at the any disaster. For achieving it, we investigated the standard of disaster management selected by the government called "Incident Preparedness and Operational Continuity Plan" Guideline, and investigated a guideline to be easily applied to domestic companies. And, we also studied on how to build the operational plan of disaster mitigation and apply IT techniques to A corporation. Especially, this study indicates the models of establishment of risk assessment, impact analysis, prevention and mitigation plan, response management plan for the establishment of plan among 5 main steps on "Incident Preparedness and Operational Continuity Management" Guideline. We devised the plan to activate the disaster mitigation activity throughout the country. It shows the skills to be prepared to upgrade the level of disaster response in this study.

In vitro and In vivo Activities Studies of Chois Mastic Using Self-microemulsifying Drug Delivery System (SMEDDS) against Helicobactor pylori (자가미세유화시스템을 이용한 매스틱의 헬리코박터파일로리 대한 In vitro 및 In vivo 활성 연구)

  • Kim, Su-Ji;Jeong, Sang-Young;Gil, Young-Sig;Shin, Byung-Cheol;Hwang, Sung-Joo;Cho, Sun-Hang
    • YAKHAK HOEJI
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    • v.55 no.1
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    • pp.1-10
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    • 2011
  • Mastic is a bleed resin formed in pistacia lentiscus tree extract form the anacatdiaceae family. Mastic is used as a food ingredient in the Mediteraanean resin, and has been used by local inhabitants as a traditional medicine for relief of upper abdominal discomfort, dyspepsiaand peptic ulcer. Clinically, mastic has been effective in the treatment of benign gastric and duodenal, ulcers, giving symptomatic relief and endoscopically proven healing. In this study, to enhance activiteies of poorly water soluble Mastic with oils, surfactants and cosurfactants and then the mixure was microemulsified in aqueous media under condition of gentle agitation and digestive motility that would be encountered in the gastrointestinal tract. Formulation development and screening were based on phase diagrams and characteristics of resultant microemulsion. For optimum mastic formulation, microemulsions with various ratio (w/w%) of mastics, oils, surfactants and cosurfactants were prepared and their solubility was evaluated by monitoring particles size in their buffer through visual asessment and electrophoretic light scattering spectrophotomerter (ELS). In vitro activity of self microemulsified mastic (SME mastic) was determined by minimum ingibition concentration (MIC) test against a panel of Helicobacter pylori (H. pylori) clinical strains. Additionally, in vivo activity of SME masitc was investigated us mouse infected by CH275 of H. pylori. The mean diameter of SME mastic was less then 100 nm in water and SME mastic was showed similar antiboisis effect compared to tometronidazole, clarithromycin and omeproazole. Consequently, SME mastic would be effective system to exterminate H. pylori. If mastic were dose with combined treatment, mastic might augur well for effect of H. pylori eradication as good remedy.

Formulation and Pharmaceutical Properties of Local Mucoadhesive-Patch Preparation (국소치료용 구강점막패취의 제제설계 및 약제학적 특성)

  • Lee, Gye-Ju;Shu, Hyun-Joo;Lee, Duck-Geun;Park, Jong-Bum;Shin, Kwang-Hyun;Hwang, Sung-Joo
    • YAKHAK HOEJI
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    • v.42 no.2
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    • pp.187-195
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    • 1998
  • In order to ameliorate disadvantages of buccal ointments and mucoadhesive tablets used for the treatment of aphthosis, a thin mucoadhesive patch containing triamcinolone acetoni de was designed and evaluated for the pharmaceutical properties. The adhesive gel layer consisting of Noveon AA-1, hydroxypropylcellulose-M and ethylcellulose N 100, and the protective gel layer of ethylcellulose N 100, Eudragit RSPO and castor oil have been formulated and various properties such as viscosity of drug gel layer, thickness, in vitro adhesion time, adhesive strength, surface pH, content uniformity and drug release are tested. The mean viscosity of drug-containing gel layer was found to increase with increasing amount of Noveon OAA-1 or hydroxypropylcellulose-M. The optimum formulation showed the thickness of 171 ${\mu}$m, surface pH of 4.6, in vitro adhesion time of 8 hours and adhesive strength of 272.7g/sheet. The drug content of each patch was relatively homogeneous with the value of 273${\pm}$6.77g. Drug release study showed that compared to mucoadhesive tablet, the patch showed a faster drug release. Drug release was delayed by hydroxypropylcellulose-M, but not by ethylcellulose N 100. The patches prepared were nonirritant and the muco adhesion was better than the commercial product (AftachR) on the market. Based on these results, this mucoadhesive patch is expected to be an effective dosage form for the treatment of aphthosis.

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Combined Artificial Bee Colony for Data Clustering (융합 인공벌군집 데이터 클러스터링 방법)

  • Kang, Bum-Su;Kim, Sung-Soo
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.203-210
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    • 2017
  • Data clustering is one of the most difficult and challenging problems and can be formally considered as a particular kind of NP-hard grouping problems. The K-means algorithm is one of the most popular and widely used clustering method because it is easy to implement and very efficient. However, it has high possibility to trap in local optimum and high variation of solutions with different initials for the large data set. Therefore, we need study efficient computational intelligence method to find the global optimal solution in data clustering problem within limited computational time. The objective of this paper is to propose a combined artificial bee colony (CABC) with K-means for initialization and finalization to find optimal solution that is effective on data clustering optimization problem. The artificial bee colony (ABC) is an algorithm motivated by the intelligent behavior exhibited by honeybees when searching for food. The performance of ABC is better than or similar to other population-based algorithms with the added advantage of employing fewer control parameters. Our proposed CABC method is able to provide near optimal solution within reasonable time to balance the converged and diversified searches. In this paper, the experiment and analysis of clustering problems demonstrate that CABC is a competitive approach comparing to previous partitioning approaches in satisfactory results with respect to solution quality. We validate the performance of CABC using Iris, Wine, Glass, Vowel, and Cloud UCI machine learning repository datasets comparing to previous studies by experiment and analysis. Our proposed KABCK (K-means+ABC+K-means) is better than ABCK (ABC+K-means), KABC (K-means+ABC), ABC, and K-means in our simulations.

Kinematic Optimization and Experiment on Power Train for Flapping Wing Micro Air Vehicle (날갯짓 초소형 비행체의 끈을 이용한 동력 전달 장치에 대한 기구학적 최적화 및 실험)

  • Gong, Du-Hyun;Shin, Sang-Joon;Kim, Sang-Yong
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.30 no.4
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    • pp.289-296
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    • 2017
  • In this paper, geometrical optimization for newly designed flapping mechanism for insect-like micro air vehicle is presented. The mechanism uses strings to convert rotation of motor to reciprocating wing motion to reduce the total weight and inertial force. The governing algorithm of movement of the mechanism is established considering the characteristic of string that only tensile force can be acted by string, to optimize the kinematics. Modified pattern search method which is complemented to avoid converging into local optimum is adopted to the geometrical optimization of the mechanism. Then, prototype of the optimized geometry is produced and experimented to check the feasibility of the mechanism and the optimization method. The results from optimization and experiment shows good agreement in flapping amplitude and other wing kinematics. Further research will be conducted on dynamic analysis of the mechanism and detailed specification of the prototype.

A hybrid identification method on butterfly optimization and differential evolution algorithm

  • Zhou, Hongyuan;Zhang, Guangcai;Wang, Xiaojuan;Ni, Pinghe;Zhang, Jian
    • Smart Structures and Systems
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    • v.26 no.3
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    • pp.345-360
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    • 2020
  • Modern swarm intelligence heuristic search methods are widely applied in the field of structural health monitoring due to their advantages of excellent global search capacity, loose requirement of initial guess and ease of computational implementation etc. To this end, a hybrid strategy is proposed based on butterfly optimization algorithm (BOA) and differential evolution (DE) with purpose of effective combination of their merits. In the proposed identification strategy, two improvements including mutation and crossover operations of DE, and dynamic adaptive operators are introduced into original BOA to reduce the risk to be trapped in local optimum and increase global search capability. The performance of the proposed algorithm, hybrid butterfly optimization and differential evolution algorithm (HBODEA) is evaluated by two numerical examples of a simply supported beam and a 37-bar truss structure, as well as an experimental test of 8-story shear-type steel frame structure in the laboratory. Compared with BOA and DE, the numerical and experimental results show that the proposed HBODEA is more robust to detect the reduction of stiffness with limited sensors and contaminated measurements. In addition, the effect of search space, two dynamic operators, population size on identification accuracy and efficiency of the proposed identification strategy are further investigated.

Experimental and Numerical Analysis for Effects of Two Inclined Baffles on Heat Transfer Augmentation in a Rectangular Duct (사각 덕트 내에 설치된 2개의 경사진 배플에 의한 열전달 증진 효과에 관한 실험 수치해석)

  • Kang, Ho-Keun;Ahn, Soo-Whan;Putra, Ary Bachtiar Krishna
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.11
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    • pp.751-760
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    • 2007
  • Baffles enhance heat transfer by disturbing boundary layer and bulk flow, creating impingement, and increasing heat transfer surface area. This study was performed to determine how the two inclined baffles (${\alpha}=5^{\circ}$ perforated models) placed at a rectangular channel affect heat transfer and associated friction characteristics. The parametric effects of perforated baffles (3, 6 and 12 holes) and flow Reynolds number ranging from 28,900 to 61,800 on the heated target surface are explored. Comparisons of the experimental data with the numerical results by commercial code CFX 10.0 are presented. As for the investigation of heat transfer behaviors on local Nusselt number with two baffles placed at $x/D_h=0.8$ and $x/D_h=8.0$ of the edge of baffles, it is evident that the inclined perforated baffles augment overall heat transfer significantly by both jet impingement and boundary layer separation. There exists an optimum perforation density to maximize heat transfer coefficients; i.e., the average Nusselt number increases with increasing number of holes, but the friction factor decreases with an increase in the hole number placed at baffles.

Implementation and Performance Analysis of Multi-GNSS Signal Collection System using Single USRP

  • Park, Kwi Woo;Choi, Yun Sub;Lee, Min Joon;Lee, Sang Jeong;Park, Chansik
    • Journal of Positioning, Navigation, and Timing
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    • v.5 no.1
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    • pp.11-20
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    • 2016
  • In this paper, a system that can collect GPS L1 C/A, GLONASS G1, and BDS B1I signals with single front-end receiver was implemented using a universal software radio peripheral (USRP) and its performance was verified. To acquire the global navigation satellite system signals, hardware was configured using USRP, antenna, external low-noise amplifier, and external oscillator. In addition, a value of optimum local oscillator frequency was selected to sample signals from three systems with L1-band with a low sampling rate as much as possible. The comparison result of C/N0 between the signal collection system using the proposed method and commercial receiver using double front-end showed that the proposed system had 0.7 ~ 0.8dB higher than that of commercial receiver for GPS L1 C/A signals and 1 ~ 2 dB lower than that of commercial receiver for GLONASS G1 and BDS B1I. Through the above results, it was verified that signals collected using the three systems with a single USRP had no significant error with that of commercial receiver. In the future, it is expected that the proposed system will be combined with software-defined radio (SDR) and advanced to a receiver that has a re-configuration channel.

Radar Target Segmentation via Histogram Chord Search Method (히스토그램 현 탐색방식에 의한 레이다 표적 분할 알고리즘)

  • Choi, Beyung-Gwan;Kim, WhAn-Woo
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.42 no.6
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    • pp.195-202
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    • 2005
  • An adaptive segmentation algorithm is used to efficiently target decisions in local non-stationary images. Until now, several adaptive approaches have been proposed as a method of segmentation. However, they can't be directly used for radar target detection because a radar signal has different characteristics from general images. Generally, a histogram of radar signal shows that targets have a relatively small number of frequency functions compared to the background and distribution of background, which have several shapes as the environment changes. In this paper, we propose an adaptive segmentation algorithm using a histogram chord which is a right-down line from maximum pick of frequency function. The proposed method provides thresholds which are optimum for several radar environments because the used chord for threshold search is not significantly effected by interference conditions. Simulation results show that the proposed method is superior to the traditional algorithms, global threshold method and distribution median method, with respect to detection performance.

A study on the design of an Dual Inverted-F Internal Antenna for the WLAN`s Band (WLAN대역의 듀얼 역-F형 내부 안테나 설계에 관한 연구)

  • Kang, Jeong-Jin;Kang, Seo;Jeung, Seung-Il;Kim, Wan-Sik;Lee, Jong-Arc
    • Journal of IKEEE
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    • v.7 no.2 s.13
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    • pp.223-229
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    • 2003
  • In this thesis, the characteristics of an inverted-F antenna for the 2.4GHz and 5.8GHz zwirless local area network(WLAN) have been analysed in terms of the variation of design parameters. The antenna can be integrated on WLAN for notebook printed circuit board, and the characteristics in terms of the variation of the gap between feed line and shorting stub, gap between antenna's leg and ground plane, antenna leg's width, substrate's height and dielectric constant are analysed. By using these characterization plot of design parameter, the tuning techniques are proposed to design optimum antenna. The designed antenna has 170MHz, 500MHz frequency bandwidth ,VSWR is 1.6, 1.14 and 3.5dBi gain.

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