• Journal of Pharmaceutical Investigation
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• v.30 no.1
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• pp.51-54
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• 2000

A column-switching high performance liquid chromatographic method has been developed for the determination of a fluconazole in human plasma. Each plasma sample was centrifuged for 10 min at 5000 g. After an aliqout of the supernatant was taken to nylon microcentrifuge filter, these samples were centrifuged for 10 min at 5000 g. An aliqout of the supernatant was injected directly onto the HPLC column. Deionized water was run for 2 min at a flow rate of 1.0 ml/min to retain fluconazole in an extration column, while proteins and endogenous interferences were eluted to the waste. The analyte was then back-flushed onto an analytical column, $C_{18}$ reversed-phase column. The mobile phase for analytical column, 0.01 M sodium acetate (pH 5.0)-methanol (65:35, v/v), was run at a flow rate of 1.0 ml/min. The column effluent was monitored by ultraviolet detection at 261 nm. The retention time for fluconazole was 11.76 min in human plasma. The detection limit for fluconazole in human plasma was $0.2\;{\mu}g/ml$. No interference from endogenous substances was observed.

• Journal of ILASS-Korea
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• v.10 no.1
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• pp.35-42
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• 2005

The present study has numerically and experimentally investigated the spray behavior of liquid jet injected in subsonic cross-flow. The corresponding spray characteristics are correlated with jet operating parameters. The spray dynamics are known to be distinctly different in the three regimes: the column, the ligament and the droplet regimes. The behaviors of column, penetration and breakup of liquid jet have been studied. Numerical and physical models are base on a modified KIVA code. The primary atomization is represented by a wave model base on the KH(Kelvin-Helmholtz) instability that is generated by a high interface relative velocity between the liquid and gas flows. In odor to capture the spray trajectory, CCD camera has been utilized. Numerical and experimental results indicate that the breakup point is delayed by increasing gas momentum ratio and the penetration decreases by increasing Weber number.

• Journal of ILASS-Korea
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• v.14 no.3
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• pp.97-102
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• 2009

The spray characteristics of the high speed rotating fuel injection system were studied. The five variants of rotating fuel nozzle were used by spray test. The diameter of single column injection orifices are varied from 1 mm, 2 mm, 3 mm, 4 mm and 5 mm. We constructed high speed rotating test rig and measured droplet size by PDPA (Phase Doppler Particle Analyzer) system. Also spray was visualized by using high speed camera. In the test results, we could understand that length of liquid column from the injection orifice is mainly controlled by the rotational speeds. SMD is decreased with increasing injection orifice diameter and rotational speeds. Furthermore, from the comparison to the theoritical calculation, we confirmed that SMD is influenced by the liquid film thickness which is formed inner surface of injection orifice.

• Structural Engineering and Mechanics
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• v.53 no.6
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• pp.1127-1141
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• 2015

The optimum design of liquid column dampers in seismic vibration control considering system parameter uncertainty is usually performed by minimizing the unconditional response of a structure without any consideration to the variation of damper performance due to uncertainty. However, the system so designed may be sensitive to the variations of input system parameters due to uncertainty. The present study is concerned with robust design optimization (RDO) of liquid column vibration absorber (LCVA) considering random system parameters characterizing the primary structure and ground motion model. The RDO is obtained by minimizing the weighted sum of the mean value of the root mean square displacement of the primary structure as well as its standard deviation. A numerical study elucidates the importance of the RDO procedure for design of LCVA system by comparing the RDO results with the results obtained by the conventional stochastic structural optimization procedure and the unconditional response based optimization.

• Transactions of the Korean Society of Mechanical Engineers
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• v.12 no.5
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• pp.984-991
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• 1988

Liquid column separation occurs when the valve on the pipeline is closed rapidly in an oil hydraulic system. In this case two-step pressure rise is sometimes observed in a comparatively short pipeline. In this study the two-step pressure rise phenomenon was investigated experimentally and theoretically. The experiments showed that maximum pressure values during two-step pressure rise might exceed extremely the values computed by the theory of rigid-liquid-column separation. So the two-step pressure rise phenomenon appears one of important factors of pipe strength design. From the theoretical considerations based on the experimental and numerical results, the mechanism of two-step pressure rise phenomenon could be explained clearly.

• Journal of the Korean Society of Propulsion Engineers
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• v.22 no.2
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• pp.1-10
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• 2018

This study investigated the acoustic forcing effects on the liquid column breakup length and the trajectory of liquid jets in crossflows. Cold-flow tests with a single hole circular nozzle injector were carried out by changing the injection pressure and acoustic forcing amplitude. Additionally, spray images were obtained at 12 phase angles to investigate the influence of the phage angle. The results revealed that the liquid column breakup lengths generally decreased under the acoustic forcing conditions, in comparison to those under the non-acoustic forcing conditions. However, they were not affected by the variation in the phase angles. On the contrary, it was found that the acoustic forcing hardly influenced the liquid column trajectories.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.19 no.8
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• pp.850-856
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• 2009

A new type bi-directional damper using a tuned liquid column damper(TLCD) and a tuned sloshing damper(TSD) is introduced in this study. Two dampers are usually needed to reduce wind-induced responses of tall buildings since they are along and across wind ones. The proposed damper has the advantage of controlling both responses with one damper. One of objectives of this study is to derive analytical dynamics to investigate coupled effects due to TLCD and TSD. Another objective is to address the effect of coupled control force due to TLCD and TSD on the dynamic characteristic of the damper based on analytical dynamics. Shaking table test is undertaken to experimentally grasp dynamic characteristics of the damper under white noise excitation. Its dynamic characteristic is expressed by the transfer function from the shaking table acceleration to the control force generated from the damper. Finally, its design parameters are identified based on the coupled dynamics, which include the mass ratio of horizontal liquid column to total liquid for a TLCD, the participation factor of the fundamental liquid sloshing for a TSD and damping ratio for both cases.

• Korean Journal of Food Science and Technology
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• v.30 no.6
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• pp.1247-1251
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• 1998

A method is developed for simultaneously determining ethanol and acetic acid in vinegars by quantitative packed-column gas chromatography. Vinegars were filtrated and directly chromatographed on a $2\;m{\times}2\;mm$ stainless steel column packed with Tenax-GC, 80/100. Ethanol, isopropy alcohol as an internal standard, and acetic acid were completely separated within 20 min of running time without any interfering peaks. The accuracy of packed column gas solid chromatography (PCGSC) was discussed compared to the analytical data by titration, high performance liquid chromatography and capillary column gas liquid chromatography (CCGLC).

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.12
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• pp.3276-3286
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• 1994

In most direct contact liquid-liquid heat exchangers, oil or hydrocarbon with a density less than water is normally used as dispersed working fluid. The main difficulty that arises with this arrangement lies in the control of the interface at the top of the column. When it is connected with a solar collector which uses water as its working fluid, the main difficulties arise from the fact that the water can be frozen during winter time. In order to solve these problems and to demonstrate the technical feasibility of a direct contact liquid-liquid heat exchanger, liquids heavier than water with low freezing temperature has been utilized as dispersed phase liquids in a small laboratory scale model made of pyrex glass. In the present investigation, dimethyl phthalate(C/sub 6/H/sub 4/)COOCH/sub 3/)/sub 2/) and diethyl phthalate (C/sub 6/H/sub 4/(CO/sub 2/C/sub 2/H/sub 5/)/sub 2/) are utilized as heavy dispersed phase working fluids. The results of the present investigation the technical in the utilization of heavier dispersed working liquid in the spray-column liquid-liquid heat exchanger for a solar system. The overall average temperature difference along the column is found to be almost half of the initial temperature difference between the dispersed and the continuous phase. Despite the fact that the two phthalates tested in the experiment differ significantly in some of their physical properties, the volumetric heat transfer coefficients in terms of dispersed fluid superficial velocities were found to be similar for both phthalates tested.

• Structural Engineering and Mechanics
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• v.83 no.5
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• pp.655-669
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• 2022

Passive vibration control devices like tuned liquid column dampers (TLCD) not only significantly reduce buildings' vibrations but also can serve as a water storage facility. The recently introduced modified form of TLCD known as tuned liquid column ball damper (TLCBD) suppressed external vibration efficiently compared to traditional TLCD. For excellent performance, the mass ratio of TLCBD should be in the range of 5% to 7%, which does not include the mass of the ball. This additional mass of the ball increases the overall structure mass. Therefore, in this paper, an effort is made to reduce the mass of TLCBD. For this purpose, a new modified version of TLCBD known as tuned liquid column hollow ball damper (TLCHBD) is proposed. The existing mathematical modeling of TLCBD is used for this new damper by updating the numerical values of the mass and mass moment of the ball. Analytically the optimal design parameters are obtained. Numerically the TLCHBD is investigated with a single degree of freedom structure under harmonic and seismic loadings. It is found that TLCHBD performance is similar to TLCBD in both loadings' cases. To validate the numerical results, an experimental study is conducted. The mass of the ball of TLCHBD is reduced by 50% compared to the ball of TLCBD. Both the arrangements are studied with a multi-degree of freedom structure under harmonic and seismic loadings using a shake table. The results of the experimental study confirm the numerical findings. It is found that the performance behavior of both the dampers is almost similar under harmonic and seismic loadings. In short, the TLCHBD is lighter in weight than TLCBD but has a similar vibration suppression ability.