• 제목/요약/키워드: liposarcoma

검색결과 79건 처리시간 0.023초

Induction of Heme Oxygenase-1 By 15-Deoxy-Delta12,14-Prostaglandin J2 Is Mediated Through Activation of Transcription Factor Nrf2 in Mcf-7 Cells

  • Kim, Eun-Hee;Surh, Young-Joon
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2003년도 추계학술대회
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    • pp.180-180
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    • 2003
  • Peroxisome proliferator-activated receptor gamma (PPAR-gamma), a member of the nuclear hormone receptor superfamily, is involved in the suppression of growth of several types of tumors such as liposarcoma, cancers of breast, prostate, and colon, possibly through induction of cell cycle arrest and/or apoptosis.(omitted)

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악성 섬유성 조직구종의 조직학적 소견에 의한 진단 (Diagnosis of Malignant Fibrous Histiocytoma(MFH) By Histologic Findings)

  • 최일용;김태승;박해인;임병구;고영혜
    • 대한골관절종양학회지
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    • 제1권1호
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    • pp.77-83
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    • 1995
  • 1. 연부 조직과 골 조직사이에서의 악성 섬유성 조직구종의 근본적인 조직학적 차이는 없었다. 2. 악성 섬유성 조직구종은 조직학적 소견이 다양하므로, 확진을 위해서는 다른 종양을 반드시 배제하여야한다. 3. 재발시 다른 형태의 조직 소견을 보여줄 수 있기 때문에 정확한 진단을 위해 환자의 과거력 및 과 거의 조직학적 검토가 필수적이라 사료된다.

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지방육종의 치료에서 술후 방사선 치료의 역할 (Role of Post-operative Irradiation in Treatment of Liposarcoma)

  • 강용구;박원종;송석환;김형민;이승구;우영균;김정만;문명상;인용
    • 대한골관절종양학회지
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    • 제1권2호
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    • pp.194-199
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    • 1995
  • To evaluate the role of post-operative irradiation in reducing local recurrence after surgical treatment of liposarcoma, 19 patients who were treated between July 1988 and June 1994 at Department of Orthopedic Surgery, Catholic University were studied retrospectively. The average follow up was 31 months. 1. There were 14 males and 5 females and an average age was 51 years old. 2. Thirteen cases were in extremities and buttock, 3 in neck, 2 in retroperitoneum and 1 in back. 3. Histologic types were 16 cases of myxoid type and 3 cases of well differentiated type. 4. Ten cases were achieved with wide margin and 9 with inadequate(intralesional or marginal) margin. 5. There were no local recurrence in 10 cases with wide margin, whereas 6(67%) local recurrences in 9 cases with inadequate margin. 6. Among 6 cases of local recurrence, 5 cases had been treated with post-operative irradiation. In conclusion, post-operative irradiation for inadequate margin(intralesional or marginal margin) was not sufficient to reducing local recurrence.

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목뒤부위에 발생한 방추세포 지방종의 치험례 (Spindle cell lipoma of the posterior neck: A case report)

  • 박선희;임영민;정성노;권호
    • Archives of Plastic Surgery
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    • 제36권2호
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    • pp.233-236
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    • 2009
  • Purpose: Spindle cell lipoma(SCL) is an uncommon subcutaneous soft tissue neoplasm that arises in the shoulder and posterior neck of older male patients. The imaging appearance of SCL is not pathognomonic and can display some features overlapping with liposarcoma. We report a case of SCL on the posterior neck. Method: The patient is a 50 - year - old man with a slowly enlarging subcutaneous mass on the right side of posterior neck. Computed tomographic imaging revealed a 7.0 cm sized, well - circumscribed, heterogenous and fatty mass with enhanced solid components. Whole body Fluorine - 18 Fluorodeoxyglucose Positron emission tomogram(FDG PET-CT) showed little increase of FDG uptake on the right posterior neck and there was no distant metastasis. Results: The mass was surgically removed. The resection margin was free of tumor on frozen biopsy. Histopathologic examination indicated spindle cell lipoma consisting of a mixture of mature adipocytes and uniform spindle cells within a matrix of mucinous material. Conclusion: Although CT image of solidtary mass in posterior neck is similar with the one of liposarcoma, we should consider that it may be a spindle cell lipoma if PET-CT and other systemic studies reveal no distant metastasis. And we should perform fine needle aspiration to differentiate SCL from malignant lesions.

개에서 겸상인대에서 유래된 분화지방육종의 영상의학증례 (Medical Imaging of Well-differentiated Liposarcoma Arising from the Falciform Fat in a Dog)

  • 정동인;김재환;하지영;박기태;연성찬;이희천
    • 한국임상수의학회지
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    • 제29권2호
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    • pp.186-189
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    • 2012
  • 7세령의 중성화수컷 코커스파니엘견이 심한 복부팽만을 주증으로 경상대학교 부속동물병원에 내원하였다. 복부방사선상에서 매우 크고 균일한 지방밀도를 보이는 종괴가 확인되었다. 복부초음파검사결과, 종괴는 불규칙한 고에코성의 피막으로 둘러싸여 있었으며, 내부는 세포성의 저에코 액체로 채워져 있었다. 컴퓨터 단층촬영결과, 내부는 지방감쇠를 보이며 주변부는 연부조직감쇠를 보이는 불균질한 종괴로 확인되었으며, 종괴의 기원은 수술적 적출시 겸상 인대에서 유래됨을 확인하였다. 절제된 종괴는 견고하고 적갈색의 표면을 나타내었다. 조직병리학적 검사결과, 분화 지방육종으로 진단되었다. 수술 1개월경과후 재검에서 환자는 특이적인 임상증상을 보이지 않았다.

광범위후외측개흉술에 의한 "Dumbbell" 종격동종양수술지험 -3례 보고- (Extended Posterolateral Thoracotomy for "Dumbbell" Mediastinal Tumor -Report of 3 Cases-)

  • Oh, Bong-Suk;Kim, In-Gwang;Kim, Su-Han;Jeong, Jae-Yoon
    • Journal of Chest Surgery
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    • 제28권11호
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    • pp.1071-1074
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    • 1995
  • Approximately 9.8% of neurogenic tumors of the mediastinum extend into the spinal column so that the composite neoplastic mass was dumbbell shaped. We experienced three patients confirmed by Dumbbell shaped mediastinal tumor radiologically and tried surgical resection by posterolateral thoracotomy only corpectomy and costotransversectomy was performed simultaneously in three patients and interbody fusion in two. In one patient the diagnosis was liposarcoma and in 1 neuroblastoma and in 1 neurilemmoma. then followed by radiation theraphy in case I and radiation and chemotheraphy in case II. All three cases showed satisfactory results clinically and radiographically.

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Cutaneous Liposarcoma in a Mongrel Dog

  • Lee, Jae-Hee;Hwang, Mee-Na;Han, Man-Gil;Jang, Se-Ung;Hong, Yeun-Jung;Lee, Gi-Jong;Jung, In-Sung
    • 한국임상수의학회:학술대회논문집
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    • 한국임상수의학회 2007년도 춘계학술대회
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    • pp.110-110
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    • 2007
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하퇴 슬와부 및 전외측 구획을 침범한 지방육종 환자의 절제 및 재건술 - 증례보고 - (Resection and Reconstruction for Liposarcoma Involving Popliteal Fossa and Antero-lateral Compartment of Lower Leg - A Case Report -)

  • 원호현;홍윤석;전대근
    • 대한골관절종양학회지
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    • 제15권1호
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    • pp.69-74
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    • 2009
  • 슬와부위의 연부조직육종은 사지의 연부조직 육종 중 5% 이하를 차지하는 드문 질환이다. 주요 혈관과 신경이 지나가는 슬와, 주와, 서혜부와 같은 구획외 공간에서는 사지 구제술 시 적절한 절제연을 얻으면서 절제를 시행하기가 쉽지 않으며 불가피하게 변연부 절제를 시행해야 하는 경우도 있다. 슬와부 종양 절제시는 후방 도달법을 시행하는 경우가 일반적이다. 크기가 작고 주변 조직에 유착이 없는 종양일 경우 후방 도달법으로 신경다발막과 혈관외막을 박리하여 종양을 쉽게 절제할 수 있다. 그러나 종양의 크기가 크고 주변조직으로 침범이 있는 경우에는 종양의 절제 자체가 어려울 수 있다. 이런 경우는 절단술의 상대적 적응증이며 종양이 전방 및 후방 구획을 동시에 침범하였을 경우에는 절단술이 불가피하다고 생각되는 경우가 많았다. 저자들은 전방 및 후방 구획을 동시에 침범한 연부조직종양을 골 외측으로 종괴를 형성한 골종양으로 간주하여 근위 경골과 비골을 종양과 함께 절제함으로써 적절한 절제연을 얻으면서 사지구제술이 가능하였기에 보고하는 바이다.

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대퇴골에 발생한 방골성 지방종 - 1례 보고 - (Parosteal Lipoma in the Femur - A Case Report -)

  • 강용구;이한용;고해석;유기원;송주현;장일석
    • 대한골관절종양학회지
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    • 제5권1호
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    • pp.82-85
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    • 1999
  • A parosteal lipoma is a benign tumor containing mature adipose tissue and is intimately related to the adjacent periosteum. We experienced a very rare case of parosteal lipoma arising from the shaft of femur. A 46 years old lady visited the hospital with complaining of slowly growing mass in her thigh for 7 month. Initially, it was difficult to differentiate from osteochondroma, parosteal osteosarcoma or liposarcoma. Based on the assessment of plain radiogram and magnetic resonance imaging, it was suspected the parosteal lipoma or osteosarcoma. Marginal excision was performed, and it was confirmed to parosteal lipoma histologically. We present the case with review of literatures.

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심낭종양[14례] (Pericardial Tumor: 14 cases)

  • 박희철;이홍균
    • Journal of Chest Surgery
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    • 제15권1호
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    • pp.118-123
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    • 1982
  • Fourteen cases of pericardia I tumor were clinically experienced from June 1966 to July 1981, for 15 years in St. Mary's Hospital, Department of Thoracic and Cardiovascular Surgery, Catholic Medical College. There were three primary tumors of the pericardium, liposarcoma, teratoma and malignant mesothelioma, and 11 metastatic pericardial tumors. In metastatic pericardial tumors, eight were originated from the lung, one was breast, and the other two cases were unknown origin. There were 6 adenocarcinoma, one small cell carcionoma ~nd one alveolar cell carcinoma in 8 cases from the lung, and 5 male and 3 female patients were composed the metastatic pericardial cancer from the lung. In clinical symptoms were dyspnea in all cases, and 9 cases had the generalized edema and enlarged liver size. Six patients had been operated, three of the primary pericardial tumor and three of metastatic pericardial tumor. Two of the primary tumors were cured satisfactorily by the mass removal, but one died due to cardiac arrest at postoperative one day. In metastatic tumors, operation were performed as two pericardial window formation and one left lower lobectomy with pericardial fenestration, but one was died in second operative day. Other nine metastatic tumors were diagnosed by needle biopsy in one case and by cell block of effusion in eight cases.

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