• Investigative Magnetic Resonance Imaging
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• v.26 no.1
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• pp.66-70
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• 2022

Paratesticular liposarcoma is a very rare tumor that is typically reported as isolated cases of or as components of larger studies of liposarcomas. Image findings are similar to those of other anatomic sites, but in less-common sites, their appearance may be less familiar, and they may be mistaken for other pathologies. In addition, atypical image findings of liposarcoma make diagnosis more difficult. Herein, we report on the case of a 45-year-old male patient who presented with a painless, palpable mass in the right scrotum. The patient was diagnosed with paratesticular liposarcoma by excisional biopsy.

• Korean Journal of Head & Neck Oncology
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• v.19 no.1
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• pp.71-74
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• 2003

Liposarcoma is one of the most common malignancies originating from human soft tissue. Because most of liposarcoma occur in the lower extremities or retroperitoneum, there are few reports about liposarcoma of head and neck region, including larynx and pharynx. Histologically, there are four types of liposarcoma, and prognosis and recurrence rate are different according to histologic subtype. Wide excision is the treatment of choice and liposarcoma hardly respond to primary radiotherapy. A 56-year-old man presented with voice change and foreign body sensation in laryngopharynx. Hypopharyngeal liposarcoma was diagnosed by surgical biopsy and performed totallaryngopharyngoesophagectomy and gastric pull-up. Here we report our experience on this case with review of literature.

• Archives of Plastic Surgery
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• v.34 no.1
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• pp.119-122
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• 2007

Purpose: Although liposarcoma is the second most common soft tissue sarcoma in adults, the incidence of liposarcoma of the head and neck is rare. There is only one reported case in Korea and moreover, only in adolescence. We report a case of liposarcoma on the neck in a 32-year-old male in adult. Methods: The patient had a slow growing, none tender mass on the posterior neck without lymphadenopathy, which has been present for 3 years and recurred twice during that time. MRI showed a 1.5 cm sized ovoid, well demarcated mass that was located in the subcutaneous layer of the posterior neck. Results: The mass was surgically removed. The resection margin was free of tumor on frozen biopsy and histopathologic examination indicated myxoid and round cell liposarcoma. The whole body F-18 FDG PET-CT applied on the fourteenth day postoperatively, revealed a moderate FDG-uptaking soft tissue lesion showing postoperative wound healing process on the posterior neck region and there was no distant metastasis. Conclusion: Liposarcoma is the second most common soft tissue sarcoma in adults. But, it rarely involves the head and neck region. Prognosis is principally dependent on histologic subtype and grade. Low grade liposarcoma such as well differentiated and myxoid liposarcoma tend to recur locally, rarely metastasize. On the other hand, high grade liposarcoma such as round cell and pleomorphic liposarcoma have higher rates of local recurrence and distant metastasis. Complete surgical excision provides the most effective means of treatment. Radiotherapy or chemotherapy can be used as an asjunctive treatment modality.

• Korean Journal of Head & Neck Oncology
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• v.28 no.2
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• pp.139-142
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• 2012

Liposarcoma is the second most common soft tissue sarcoma in adult. The incidence of liposarcoma in the head and neck area is very uncommon. Liposarcoma of the neck usually express non-tender palpable mass. The main treatment of cervical liposarcoma is surgical excision and adjuvant radiation therapy. Herein, we report a case of cervical liposarcoma with the review of literature.

• Investigative Magnetic Resonance Imaging
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• v.21 no.4
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• pp.252-258
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• 2017

Primary mesenteric liposarcoma is rare. It is difficult to make an accurate preoperative diagnosis of the myxoid type of liposarcoma by using imaging such as ultrasound or computed tomography (CT) due to the very small amount of fat that is located in the tumor. We report a case of primary myxoid liposarcoma of the mesentery which was difficult to differentiate from other solid mesenteric tumors with a myxoid component such as low grade fibromyxoid sarcoma, myxoid leiomyosarcoma or myxoma. Use of chemical shift magnetic resonance (MR) imaging to detect small fat components and its cystic appearance with solid components on the MR images can be useful to differentiate myxoid liposarcoma from the other mesenteric tumors with a myxoid component.

• Journal of Chest Surgery
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• v.37 no.11
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• pp.942-945
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• 2004

Primary pulmonary liposarcoma is extremely rare disease. It has poor prognosis with early multiple metastases and frequent local recurrences. Surgery is the choice of treatment for liposarcoma. Incomplete resection would result in rapid and aggressive growing of the tumor. We report a case of primary pulmonary liposarcoma which was successfully treated with complete resection without local recurrence and distant metastasis for 10 months.

• Journal of Clinical Otolaryngology Head and Neck Surgery
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• v.29 no.2
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• pp.295-300
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• 2018

Pleomorphic liposarcoma is extremely rare in the head and neck region. It can be diagnosed by identifying multivacuolated lipoblast with pleomorphism. Most studies have reported that pleomorphic liposarcoma shows an aggressive behavior with poor prognosis. The treatment of choice is wide resection to ensure negative margin. The authors report a case of pleomorphic liposarcoma in a 67-year-old female, who was treated with primary resection of tumor and postoperative radiation therapy. The patient is well without any recurrence or metastasis after 1 year of follow-up.

• Korean Journal of Head & Neck Oncology
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• v.37 no.2
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• pp.71-75
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• 2021

Liposarcoma is a very rare malignant tumor affecting the head and neck area. Since it is an invasive and life-threatening disease, active treatments is necessary. However, differential it from lipoma, its corresponding benign counterpart, may be difficult. Herein, we report a rare case of posterior neck myxoid liposarcoma in a 72-year-old man who was initially misdiagnosed with lipoma, including a literature review of differential diagnosis between lipoma and liposarcoma.

• Korean Journal of Head & Neck Oncology
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• v.26 no.2
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• pp.256-258
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• 2010

Although liposarcoma is the second most common soft tissue sarcoma in adults, the incidence of liposarcoma in the head and neck is low. The histologic nature of liposarcoma is correlated clinically with treatment outcome, but histologic classification of liposarcoma is controversial. Well-differentiated liposarcoma and atypical lipoma are pathologic synonyms because they are identical lesions both morphologically and karyotypically. They represent the lowest grade lesions in the spectrum of liposarcoma. The terms "atypical lipoma" were introduced specifically to describe well-differentiated liposarcomas occurring in the extremities, because of their better prognosis in comparison with their retroperitoneal counterparts. We present 1 case of atypical lipomatous tumor of the neck.

• Journal of the Korean Orthopaedic Association
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• v.55 no.4
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• pp.331-337
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• 2020

Purpose: The aim of this retrospective study was to define the prognostic factors for liposarcoma to aid in the selection of effective treatments. Materials and Methods: This study analyzed 41 cases out of 45 cases diagnosed with and treated for liposarcoma 2002 to 2015; 4 cases of well-differentiated liposarcoma were excluded. The effects of sex, age, site, stage, and histological classification on survival were analyzed retrospectively. For 28 cases diagnosed with myxoid liposarcoma, additional analysis was performed after the inclusion of round cell components. Results: The mean age at diagnosis was 52.05 years (range 25-82 years) and the average follow-up period was 63.7 months. The disease-free survival rate was 43.2%. Most factors, including sex and age, were not significantly associated with the survival rate. On the other hand, the stage (Musculoskeletal Tumor Society stage) was significantly associated with the survival rate. The survival rate of patients with myxoid liposarcoma was 69% and the local recurrence and metastasis results varied according to the presence of round cells. Conclusion: The stage of liposarcoma and the sex of the patient were found to be effective factors for prognosis. When planning the treatment for liposarcoma, the treatment outcome for liposarcoma differs according to several prognostic factors.