• Maxillofacial Plastic and Reconstructive Surgery
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• v.32 no.3
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• pp.218-228
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• 2010

Components of dental resin-based restorative materials are reported to leach from the filling materials even after polymerization. Hydroquinone (HQ) is one of the major monomers used in the dental resin and is known as a carcinogen. Thus, carcinogenic risk of HQ leaching from the dental resin becomes a public health concern. The present study attempted to examine the carcinogenic potentials of HQ on the human epithelial cell, which is the target cell origin of the most of oral cancers. Cytotoxicity of HQ was observed above 50${\mu}M$ as measured by LDH assay, indicating a relatively low toxicity of this substance in human epithelial cells. The parameters of neoplastic cellular transformation such as cell saturation density, soft agar colony formation and cell aggregation were analyzed to examine the carcinogenic potential of HQ. The study showed that 2-week exposure of HQ showed the tendency of increase in the saturation density and the significant enhancement of soft agar colony formation at the highest dose, 50 ${\mu}M$ only. It is suggested that HQ has a weak potential of carcinogenicity. When cells were treated with HQ and TPA, a well-known tumor promoter, the parameters of neoplastic cellular transformation was significantly increased. This result indicates that the potential risk of carcinogenicity from HQ is largely dependent upon the presence of promoter. Exposure of 50 ${\mu}M$ HQ increased the time-dependent apoptosis as measured by the ELISA kit. This concentration coincides with a dose of neoplastic transformation, indicating a possible link between apoptosis and HQ-induced cellular transformation. Hydroquinone generated Reactive Oxygen Species (ROS) which was evidenced by the treatment of antioxidants such as trolox and N-acetyl cysteine and the GSH depleting agent, BSO. Antioxidants blocked the generation of ROS and the GSH depleting agent, BSO dramatically increased the ROS production. Since HQ is known to increase ROS production thru activation of transcriptional factor such as c-Myb and Pim-1, it is speculated that ROS generation by HQ plays a role in the activation of oncogene, which may lead to neoplastic transformation. In addition, ROS is involved in the alteration of signal transduction, which regulates the apoptosis in many cellular systems. Thus, ROS-mediated apoptosis may be involved in the HQ-induced carcinogenic processes. Protein kinase C (PKC) is known to play pivotal roles in neoplastic transformation of cells and its high expression is often found in a variety of types of tumors including oral cancer. PKC translocation of PKC-${\alpha}$ was observed following HQ exposure. Altered signaling system may also play a role in the transformation process. Taken together, HQ leached from the dental resin does not pose a significant threat as a cancer causing agent, but its carcinogenic potential can be significantly elevated in the presence of promoter. The mechanism of HQ-induced carcinogenesis involved ROS generation, apoptosis and altered signaling pathway. The present study will provide a valuable data to estimate the potential risk of HQ as a carcinogen and understand mechanism of HQ-induced carcinogenesis in human epithelial cells.

• Korean Chemical Engineering Research
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• v.55 no.5
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• pp.586-592
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• 2017

In this study, acrylic resins with solids content of 75% were prepared by addition polymerization of n-butyl acrylate (BA), methyl methacrylate (MMA), 2-hydroxypropyl methacrylate (HPMA) and acetoacetoxyethyl methacrylate (AAEM) monomers. At this time, the glass transition temperature ($T_g$) of the acrylic resin was changed to 20, 30 and $40^{\circ}C$, and the hydroxyl value (OH value) was changed to 60, 90 and 120. As a result, the viscosity of acrylic resin increased with increasing $T_g$ and hydroxyl (OH) value. The synthesized acrylic resin was designed to have a high cross-link density to maintain high elasticity and high durability. The crosslinked acrylic resin was used to prepare an acrylic urethane clear coating by curing reaction with a block isocyanate (Desmodur BL-3175). The physical properties of the clear paints were analyzed by measuring viscosity, adhesion, pencil hardness and $60^{\circ}$ specular gloss. Acrylic urethane clear coatings were prepared as specimens and evaluated for various properties to be applied as top coatings for coil coating. The prepared coatings were excellent in adhesion, excellent in $60^{\circ}$ specular gloss and pencil hardness, and eco-friendly.

• Publications of The Korean Astronomical Society
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• v.32 no.1
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• pp.201-203
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• 2017

There exists strong evidence supporting the co-evolution of central supermassive black holes and their host galaxies; however it is still under debate how such a relation comes about and whether it is relevant for all or only a subset of galaxies. An important mechanism connecting AGN to their host galaxies is AGN feedback, potentially heating up or even expelling gas from galaxies. AGN feedback may hence be responsible for the eventual quenching of star formation and halting of galaxy growth. A rich multi-wavelength dataset ranging from the X-ray regime (Chandra), to far-IR (Herschel), and radio (WSRT) is available for the North Ecliptic Pole field, most notably surveyed by the AKARI infrared space telescope, covering a total area on the sky of 5.4 sq. degrees. We investigate the star formation properties and possible signatures of radio feedback mechanisms in the host galaxies of 237 radio sources below redshift z = 2 and at a radio 1.4 GHz flux density limit of 0.1 mJy. Using broadband SED modelling, the nuclear and host galaxy components of these sources are studied simultaneously as a function of their radio luminosity. Here we present results concerning the AGN content of the radio sources in this field, while also offering evidence showcasing a link between AGN activity and host galaxy star formation. In particular, we show results supporting a maintenance type of feedback from powerful radio-jets.

• Journal of the Korean Wood Science and Technology
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• v.46 no.5
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• pp.486-496
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• 2018

This study was conducted to confirm an effect of span length on bending properties of larch dimensional lumber in the four point bending test. The size of specimen in this study was 38 (width) ${\times}$ 89 (depth) ${\times}$ 3,600 (length) $mm^3$, and average air-dry density and moisture content of the specimens was $543.5kg/m^3$ and 10.5%, respectively. Visually graded No. 1 dimensional lumbers of 248 were divided by two groups to compare modulus of rupture (MOR) and modulus of elasticity (MOE). One group was tested in the four point bending test with span length of 1,650 mm, and other was tested with span length of 3,000 mm. While MOE was not different according to span length in 5% significance level, MOR was different in accordance with span lengths and was in inverse proportion to change of span length. Fifth percentiles of MOR in span length of 1,650 and 3,000 mm were 28.65 and 25.70 MPa, respectively. It was confirmed that the difference between MORs in each case increased as normalized rank increased. This is because of size effect in Weibull weakest link failure theory. Therefore, KS F 2150, in which there is only regulation about span to depth ratio of 15 or more, is needed to be revised to contain a method considering size effect for MOR. From the method, various results of bending test with different size of lumber could be used to determine design value of lumber.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.4
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• pp.195-200
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• 2020

With the growing interest in fossil fuel depletion and environmental pollution, railroad cars operating in Korea are in progress as the conversion from diesel to electric vehicles expands. The photovoltaic system, which is applied as an example of the conversion of electric vehicles, is infinite and pollution-free, and can produce energy without generating hazards such as air pollution, noise, heat, and vibration, and maintain fuel transportation and power generation facilities. There is an advantage that is rarely needed. However, the amount of electricity produced depends on the amount of solar radiation by region, and the energy density is low due to the power generation of about 25㎡/ kWp, so a large installation area is required and the installation place has limited problems. In view of these problems, many studies have been applied to fuel cells in the railway field. In particular, the plan to link the fuel cell power generation system railroad power supply system must be linked to the power supply system that supplies power to the railroad, unlike solar and wind power. Therefore, it has a close relationship with railroad cars and the linkage method can vary greatly depending on the system topology. Therefore, in this paper, we study the validity through simulation modeling related to linkage analysis according to system topology.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.1
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• pp.64-77
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• 2013

In this paper, we propose a joint bandwidth allocation and path selection scheme for IEEE 802.16j networks in uplink with cooperative relaying, and we evaluate the performance of the proposed scheme by using OPNET based simulation in hilly terrain with heavy tree density. The proposed scheme maximizes the system throughput in uplink with cooperative relaying in IEEE 802.16j networks. Then, we transform the proposed scheme into multi-dimensional multiple choice knapsack problem (MMKP) based scheme. We also propose uplink throughput maximization scheme and MMKP based scheme without cooperative relaying. We show that the system throughput of the proposed MMKP based scheme is higher than that of link quality based scheme, and cooperative relaying provides higher system throughput than the conventional case without cooperative relaying in uplink.

• KEPCO Journal on Electric Power and Energy
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• v.5 no.3
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• pp.141-147
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• 2019

Recently, the biggest issue in the electricity industry is the increase in renewable energy, and various technologies are being developed to ensure the capacity of the power system. In addition, super-grids linking power systems are being pushed to utilize eco-friendly energy between countries and regions worldwide. The HVDC transmission technology is required to link the power network between regions with different characteristics of the power system such as frequency and voltage. Until now, Korea has applied HVDC transmission technology that connects mainland and Jeju Island with submarine cables. But, the HVDC transmission technology is still developing for long-distance high-capacity power transmission from power parks on the east coast to load-tight areas near the metropolitan area. Considering the high population density and mountainous domestic environment, it is pushing for commercialization of the design technology of the ${\pm}500kV$ Double Bipole with metallic return wire transmission line to transmit large-scale power of 8 GW using minimal right of ways. In this paper, the insulation characteristics were studied for the design of double-bipole transmission tower with metallic return wire, which is the first time in the world. And the air insulation characteristics resistant to the various overvoltage phenomena occurring on transmission lines were verified through a full-scale impulse voltage test.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.3A
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• pp.305-313
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• 2008

A reliability based calibration of dynamic load allowance (DLA) of highway bridge is performed by numerical dynamic analysis of various types of bridges taking into account of the road surface roughness and bridge-vehicle interaction. A total of 10 simply supported bridges with three girder types in the form of prestressed concrete girder, steel plate girder, and steel box girder is analyzed. The cross sections recommended in "The Standardized Design of Highway Bridge Superstructure" by the Korean Ministry of Construction are used for the prestressed concrete girder bridges and steel plate girder bridges while the box girder bridges are designed by the LRFD method. Ten sets of road surface roughness for each bridge are generated from power spectral density (PSD) function by assuming the roadway as "Average Road". A three dimensionally modeled 5-axle tractor-trailer with its gross weight the same as that of DB-24 design truck is used in the dynamic analysis. For the finite element modeling of superstructure, beam elements for the main girder, shell elements for concrete deck, and rigid links between main girder and concrete deck are used. The statistical mean and coefficient of variation of DLA are obtained from a total of 100 DLA results for 10 different bridges with each having 10 sets of road surface roughness. Applying the DLA statistics obtained, the DLA is finally calibrated in a reliability based LRFD format by using the formula developed in the calibration of OHBDC code.

• Journal of dental hygiene science
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• v.18 no.4
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• pp.210-217
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• 2018

Periodontal disease is a chronic inflammatory disease that affects quality of life and nutrition. Several studies have demonstrated a link between periodontal disease and low bone density, and vitamin D is expected to have a beneficial effect on periodontal disease as well as on bone mineral density and anti-inflammatory effects. The purpose of this study was to identify the association between periodontal disease and vitamin D because the results are different in some studies and there is a lack of research in Korea. In this study, we conducted a multiple linear regression analysis of 8,783 subjects among 23,626 subjects who were older than 20 years of age, who had serum vitamin D levels and periodontal disease, who had three years of the National Health and Nutrition Survey that was conducted in Korea from 2012 to 2014. We examined the relationship between serum vitamin D levels and periodontal disease. Tooth loss and vitamin D levels were negatively correlated (${\beta}=-0.028$, p=0.008). In addition, the prevalence of periodontal disease was found to be higher in men younger than 50 years of age with lower vitamin D levels (Q1: 1.769 [1.125~2.782], Q2: 1.182 [0.743~1.881], Q3: 0.676 [0.400~1.881]; p=0.001). Low vitamin D levels and periodontal disease are common diseases in primary care. Vitamin D supplementation is expected to have favorable effect on periodontal disease and falls, osteoporosis, osteoarthritis, and cancer. Therefore, patients with periodontal disease may benefit from periodic vitamin D management to improve quality of life as well as to manage periodontal disease. In addition, as shown in this study, not only elderly individuals, but also men younger than 50 years of age are related to periodontal disease, so there should be interest in controlling the levels of vitamin D in adults.

• Korean Association of Arts Management
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• no.49
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• pp.5-35
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• 2019

The main purpose of this study was to use semantic network analysis to examine the international trend of arts management and other studies pertinent to this field. The subject was based on 357 keywords listed on the abstract of 185 research papers in the International Journal of Arts Management. To examine the most current trends of arts management based studies the time frame was restricted from 2008 to 2017. To briefly summarize the result, first, 'museum' was the most frequently appeared keyword. This was followed by 'performing arts' and 'arts' with more than 20 appearances. 'Motion picture industry' and 'theater' were the next frequently appeared keywords. 'Customer behavior' and 'market strategy', keywords related to management, were also included in the high ranked group along with art related keywords. Second, yearly research trend shows that arts management has been regularly studied for past ten years with average of 19 research papers with about 53 keywords. Keywords such as 'museum' and 'performing arts' has been regularly studied for past ten years. 'Culture', 'theater' and 'motion pictures industry' does not regularly appear in the result of yearly research trend but nevertheless they have sparsely made an appearance along the past decade. 'Art gallery' has not been cited till 2011 but from 2012 it was regularly and continuously made an appearance in the yearly research trend. Overall, the yearly trend result shows that the trend of international arts management studies within IJAM, was at first centered on fine arts but as the time passed there has been diversified keywords related to management. Third, 'performing art' and 'art' has the highest link frequency(34). Fourth, density result was 0.039 which shows that the keyword density is not very high. Fifth, 'art', 'performing art', 'museum', 'theater' and 'brand' were positioned in the middle when looking at the visualized version of centrality result. This means that these five keywords has the highest centrality among other keywords.